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  1. Article: Intrathymic growing bronchogenic cyst mimicking thymoma: A case report.

    Grigoroiu, Madalina / Paisley, Sarah / Brian, Emmanuel / Natali, Delphine

    Frontiers in oncology

    2023  Volume 13, Page(s) 1121321

    Abstract: Intrathymic bronchogenic cysts are extremely rare lesions, and the differential diagnosis with a banal thymic cyst or a solid tumor can be problematic. Thymic carcinomas arising within thymic cysts have also been reported. We report a case of radical ... ...

    Abstract Intrathymic bronchogenic cysts are extremely rare lesions, and the differential diagnosis with a banal thymic cyst or a solid tumor can be problematic. Thymic carcinomas arising within thymic cysts have also been reported. We report a case of radical thymectomy for a slowly growing small thymic cyst. The pathological finding revealed a bronchogenic cyst rather than a thymic neoplasm.
    Language English
    Publishing date 2023-02-20
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2023.1121321
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Identification of Evidence for Key Parameters in Decision-Analytic Models of Cost Effectiveness: A Description of Sources and a Recommended Minimum Search Requirement.

    Paisley, Suzy

    PharmacoEconomics

    2016  Volume 34, Issue 6, Page(s) 597–608

    Abstract: This paper proposes recommendations for a minimum level of searching for data for key parameters in decision-analytic models of cost effectiveness and describes sources of evidence relevant to each parameter type. Key parameters are defined as treatment ... ...

    Abstract This paper proposes recommendations for a minimum level of searching for data for key parameters in decision-analytic models of cost effectiveness and describes sources of evidence relevant to each parameter type. Key parameters are defined as treatment effects, adverse effects, costs, resource use, health state utility values (HSUVs) and baseline risk of events. The recommended minimum requirement for treatment effects is comprehensive searching according to available methodological guidance. For other parameter types, the minimum is the searching of one bibliographic database plus, where appropriate, specialist sources and non-research-based and non-standard format sources. The recommendations draw on the search methods literature and on existing analyses of how evidence is used to support decision-analytic models. They take account of the range of research and non-research-based sources of evidence used in cost-effectiveness models and of the need for efficient searching. Consideration is given to what constitutes best evidence for the different parameter types in terms of design and scientific quality and to making transparent the judgments that underpin the selection of evidence from the options available. Methodological issues are discussed, including the differences between decision-analytic models of cost effectiveness and systematic reviews when searching and selecting evidence and comprehensive versus sufficient searching. Areas are highlighted where further methodological research is required.
    MeSH term(s) Cost-Benefit Analysis ; Decision Support Techniques ; Delivery of Health Care/economics ; Health Status ; Humans ; Models, Economic ; Research Design ; Technology Assessment, Biomedical/methods
    Language English
    Publishing date 2016-02-09
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 1100273-6
    ISSN 1179-2027 ; 1170-7690
    ISSN (online) 1179-2027
    ISSN 1170-7690
    DOI 10.1007/s40273-015-0372-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3579: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  3. Article: Adaptive grazing and animal density implications for stocking rate and drought in northern mixed-grass prairie

    Scasta, J. D. / Gergení, T. / Mączko, K. / Tanaka, J. / Paisley, S.

    Livestock science

    2023  Volume 269, Issue -, Page(s) 105184

    Language English
    Document type Article
    ZDB-ID 2226176-X
    ISSN 1871-1413
    Database Current Contents Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Z 3115: Show issues

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  4. Article ; Online: The cost-effectiveness of follow-up strategies after cancer treatment: a systematic literature review.

    Barbieri, M / Richardson, G / Paisley, S

    British medical bulletin

    2018  Volume 126, Issue 1, Page(s) 85–100

    Abstract: Introduction: The cost of treatment and follow-up of cancer patients in the UK is substantial. In a budget-constrained system such as the NHS, it is necessary to consider the cost-effectiveness of the range of management strategies at different points ... ...

    Abstract Introduction: The cost of treatment and follow-up of cancer patients in the UK is substantial. In a budget-constrained system such as the NHS, it is necessary to consider the cost-effectiveness of the range of management strategies at different points on cancer patients' care pathways to ensure that they provide adequate value for money.
    Sources of data: We conducted a systematic literature review to explore the cost-effectiveness of follow-up strategies of patients previously treated for cancer with the aim of informing UK policy. All papers that were considered to be economic evaluations in the subject areas described above were extracted.
    Areas of agreement: The existing literature suggests that intensive follow-up of patients with colorectal disease is likely to be cost-effective, but the opposite holds for breast cancer.
    Areas of controversy: Interventions and strategies for follow-up in cancer patients were variable across type of cancer and setting. Drawing general conclusions about the cost-effectiveness of these interventions/strategies is difficult.
    Growing points: The search identified 2036 references but applying inclusion/exclusion criteria a total of 44 articles were included in the analysis. Breast cancer was the most common (n = 11) cancer type followed by colorectal (n = 10) cancer. In general, there were relatively few studies of cost-effectiveness of follow-up that could influence UK guidance. Where there was evidence, in the most part, NICE guidance broadly reflected this evidence.
    Areas timely to develop research: In terms of future research around the timing, frequency and composition of follow-ups, this is dependent on the type of cancer being considered. Nevertheless, across most cancers, the possibility of remote follow-up (or testing) by health professionals other than hospital consultants in other settings appears to warrant further work.
    MeSH term(s) Continuity of Patient Care/economics ; Continuity of Patient Care/standards ; Cost-Benefit Analysis ; Follow-Up Studies ; Humans ; Neoplasms/rehabilitation ; Patient Discharge ; State Medicine ; United Kingdom
    Language English
    Publishing date 2018-04-16
    Publishing country England
    Document type Journal Article ; Systematic Review
    ZDB-ID 213294-1
    ISSN 1471-8391 ; 0007-1420
    ISSN (online) 1471-8391
    ISSN 0007-1420
    DOI 10.1093/bmb/ldy011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.277: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Are preferences over health states informed?

    Karimi, M / Brazier, J / Paisley, S

    Health and quality of life outcomes

    2017  Volume 15, Issue 1, Page(s) 105

    Abstract: Background: The use of preference-elicitation tasks for valuing health states is well established, but little is known about whether these preferences are informed. Preferences may not be informed because individuals with little experience of ill health ...

    Abstract Background: The use of preference-elicitation tasks for valuing health states is well established, but little is known about whether these preferences are informed. Preferences may not be informed because individuals with little experience of ill health are asked to value health states. The use of uninformed preferences in cost-effectiveness can result in sub-optimal resource allocation. The aim of this study was to pilot a novel method to assess whether members of the public are informed about health states they value in preference-elicitation tasks.
    Methods: The general public was said to be informed if the expectations of the public about the effect of ill health on people's lives were in agreement with the experience of patients. Sixty-two members of the public provided their expectations of the consequences of ill health on five life domains (activities, enjoyment, independence, relationships, and avoiding being a burden). A secondary dataset was used to measure patient experience on those five consequences.
    Results: There were differences between the expectations of the public and the experience of patients. For example, for all five life consequences the public underestimated the effects of problems in usual activities compared to problems in mobility. They also underestimated the effect of 'anxiety or depression' compared to physical problems on enjoyment of life and on the quality of personal relationships.
    Conclusions: This proof-of-concept study showed that it is possible to test whether preferences are informed. This study should be replicated using a larger sample. The findings suggest that preferences over health states in this sample are not fully informed because the participants do not have accurate expectations about the consequences of ill health. These uninformed preferences may not be adequate for allocation of public resources, and research is needed into methods to make them better informed.
    MeSH term(s) Activities of Daily Living ; Adult ; Attitude to Health ; Cost-Benefit Analysis ; Depression ; Female ; Health Status ; Humans ; Male ; Middle Aged ; Pain ; Pilot Projects ; Population Surveillance ; Quality of Life ; Self Care/psychology
    Language English
    Publishing date 2017-05-18
    Publishing country England
    Document type Journal Article
    ISSN 1477-7525
    ISSN (online) 1477-7525
    DOI 10.1186/s12955-017-0678-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: How do individuals value health states? A qualitative investigation.

    Karimi, M / Brazier, J / Paisley, S

    Social science & medicine (1982)

    2017  Volume 172, Page(s) 80–88

    Abstract: Despite the importance of health state values in informing resource allocation in health care, there is arguably little known about how individuals value health. Previous studies have shown that a variety of non-health factors and beliefs are important ... ...

    Abstract Despite the importance of health state values in informing resource allocation in health care, there is arguably little known about how individuals value health. Previous studies have shown that a variety of non-health factors and beliefs are important in valuing health, but there is less evidence in the literature about how individuals' beliefs affect their preferences or what role non-health factors play in the process of forming preferences. This study investigated the thought processes of 21 U.K. based participants in March 2013 who valued health states using semi-structured interviews and a think-aloud protocol, with the aim to better understand the relationship between health states, the individual's underlying beliefs, and the individual's preferences. Participants followed several stages in valuing health. First, participants interpreted the health states more concretely, relying on their imagination and their experience of ill health. Participants judged how the concrete health problems combined with their personal interests, circumstances, and environment would affect them personally. Ultimately, participants valued health by estimating and weighing the non-health consequences of the health states. Six consequences were most frequently mentioned: activities, enjoyment, independence, relationships, dignity, and avoiding being a burden. At each stage participants encountered difficulties and expressed concerns. The findings have implications for methods of describing health, for example, whether the focus should be on health or a broader notion of well-being and capability. This is because the consequences are similar to the domains of broader measures such as the ICECAP measures for adults and older people, and the Warwick-Edinburgh Mental Wellbeing Scale. The findings suggest the need for testing whether individuals are informed about the health states they are valuing. Participants valued health by estimating the non-health consequences of health states and these estimates relied on individuals' beliefs about the interaction of the health state and their personal and social circumstances.
    Language English
    Publishing date 2017
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 4766-1
    ISSN 1873-5347 ; 0037-7856 ; 0277-9536
    ISSN (online) 1873-5347
    ISSN 0037-7856 ; 0277-9536
    DOI 10.1016/j.socscimed.2016.11.027
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 625: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Innovation in information retrieval methods for evidence synthesis studies.

    Paisley, Suzy / Foster, Margaret J

    Research synthesis methods

    2018  Volume 9, Issue 4, Page(s) 506–509

    MeSH term(s) Algorithms ; Automation ; Computers ; Databases, Bibliographic ; Diffusion of Innovation ; Humans ; Information Storage and Retrieval/methods ; Information Storage and Retrieval/trends ; Review Literature as Topic
    Language English
    Publishing date 2018-11-12
    Publishing country England
    Document type Editorial
    ISSN 1759-2887
    ISSN (online) 1759-2887
    DOI 10.1002/jrsm.1322
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Innovation in information retrieval methods for evidence synthesis studies.

    Paisley, Suzy / Foster, Margaret J

    Research synthesis methods

    2018  

    Language English
    Publishing date 2018-10-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 2548499-0
    ISSN 1759-2887 ; 1759-2879
    ISSN (online) 1759-2887
    ISSN 1759-2879
    DOI 10.1002/jrsm.1325
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The Cost-Effectiveness of Expanding the UK Newborn Bloodspot Screening Programme to Include Five Additional Inborn Errors of Metabolism.

    Bessey, Alice / Chilcott, James / Pandor, Abdullah / Paisley, Suzy

    International journal of neonatal screening

    2020  Volume 6, Issue 4

    Abstract: Glutaric aciduria type 1, homocystinuria, isovaleric acidaemia, long-chain hydroxyacyl CoA dehydrogenase deficiency and maple syrup urine disease are all inborn errors of metabolism that can be detected through newborn bloodspot screening. This ... ...

    Abstract Glutaric aciduria type 1, homocystinuria, isovaleric acidaemia, long-chain hydroxyacyl CoA dehydrogenase deficiency and maple syrup urine disease are all inborn errors of metabolism that can be detected through newborn bloodspot screening. This evaluation was undertaken in 2013 to provide evidence to the UK National Screening Committee for the cost-effectiveness of including these five conditions in the UK Newborn Bloodspot Screening Programme. A decision-tree model with lifetable estimates of outcomes was built with the model structure and parameterisation informed by a systematic review and expert clinical judgment. A National Health Service/Personal Social Services perspective was used, and lifetime costs and quality-adjusted life years (QALYs) were discounted at 1.5%. Uncertainty in the results was explored using expected value of perfect information analysis methods together with a sensitivity analysis using the screened incidence rate in the UK from 2014 to 2018. The model estimates that screening for all the conditions is more effective and cost saving when compared to not screening for each of the conditions, and the results were robust to the updated incidence rates. The key uncertainties included the sensitivity and specificity of the screening test and the estimated costs and QALYs.
    Language English
    Publishing date 2020-11-20
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2409-515X
    ISSN (online) 2409-515X
    DOI 10.3390/ijns6040093
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Frame Score, Grazing and Delayed Feedlot Entry Effect on Performance and Economics of Beef Steers from Small- and Large-Framed Cows in an Integrated Crop-Livestock System.

    Şentürklü, Songul / Landblom, Douglas / Paisley, Steven / Wachenheim, Cheryl / Maddock, Robert

    Animals : an open access journal from MDPI

    2021  Volume 11, Issue 11

    Abstract: When selling small-framed steers at weaning, profitability is diminished. The hypothesis is that by using a vertically integrated business model that includes retained ownership, extended grazing, abbreviated feedlot finishing, and selling at slaughter, ... ...

    Abstract When selling small-framed steers at weaning, profitability is diminished. The hypothesis is that by using a vertically integrated business model that includes retained ownership, extended grazing, abbreviated feedlot finishing, and selling at slaughter, profitability would increase. Crossbred yearling steers (
    Language English
    Publishing date 2021-11-15
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani11113270
    Database MEDical Literature Analysis and Retrieval System OnLINE

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