Article ; Online: Effect of the type of specialized nutrition support on the course of the patient with amyotrophic lateral sclerosis (ALS). Interhospital registry SCLEDyN.
Endocrinologia, diabetes y nutricion
2021 Volume 68, Issue 10, Page(s) 699–707
Abstract: Introduction: Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease in which specialized nutritional support is essential. The objectives of our study were to describe nutritional support at the beginning of follow-up and its impact on ... ...
| Abstract | Introduction: Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease in which specialized nutritional support is essential. The objectives of our study were to describe nutritional support at the beginning of follow-up and its impact on anthropometry and survival. Methods: An interhospital registry was created for the hospitals of Castilla-León through a web platform designed for this purpose. An anamnesis was carried out on the evolution and nutritional history of the disease; and classical anthropometry was determined. The prescribed nutritional treatment was recorded. The parameters were measured at the beginning, at six and twelve months of nutritional follow-up. Results: A total of 93 patients [49 (52.7%) spinal; 44 (47.3%) bulbar)] were analyzed. The nutritional support route at the beginning was oral diet in 36 (38.7%) patients; oral nutritional supplementation (SON) in 46 (49.5%) patients; and in 11 (11.8%) patients percutaneous endoscopic gastrostomy (PEG). A decrease in the body mass index (BMI) was observed between the first and second visit [Start: 24.18 (3.29) kg/m Conclusions: Patients with ALS present a severe deterioration in nutritional status before the start of nutritional support. After the nutritional intervention, a slowdown in weight loss and nutritional deterioration was observed. |
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| MeSH term(s) | Amyotrophic Lateral Sclerosis/therapy ; Gastrostomy ; Humans ; Neurodegenerative Diseases ; Nutritional Support ; Registries |
| Language | English |
| Publishing date | 2021-12-08 |
| Publishing country | Spain |
| Document type | Journal Article |
| ISSN | 2530-0180 |
| ISSN (online) | 2530-0180 |
| DOI | 10.1016/j.endien.2021.11.032 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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