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  1. AU="Palfi Salavat, Mădălina-Casiana"
  2. AU="Mohamed, Eid"
  3. AU="Hudson, Lance"
  4. AU="Imane Mihoub" AU="Imane Mihoub"
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  1. Article ; Online: The role of Anti-VEGF agents in treatment of neovascular glaucoma.

    Palfi Salavat, Mădălina-Casiana / Șeclăman, Edward Paul / Barac, Ramona / Ungureanu, Emil / Iorgu, Gabriel / Artamonov, Andrada / Leuștean, Laurențiu / Borugă, Mădălina Veronica

    Romanian journal of ophthalmology

    2022  Volume 66, Issue 3, Page(s) 209–213

    Abstract: Aim: ...

    Abstract Aim:
    MeSH term(s) Male ; Humans ; Glaucoma, Neovascular/drug therapy ; Bevacizumab/therapeutic use ; Retrospective Studies ; Antibodies, Monoclonal, Humanized/therapeutic use ; Vascular Endothelial Growth Factor A ; Angiogenesis Inhibitors/therapeutic use ; Intraocular Pressure ; Intravitreal Injections
    Chemical Substances Bevacizumab (2S9ZZM9Q9V) ; Antibodies, Monoclonal, Humanized ; Vascular Endothelial Growth Factor A ; Angiogenesis Inhibitors
    Language English
    Publishing date 2022-10-27
    Publishing country Romania
    Document type Journal Article ; Review
    ZDB-ID 2842202-8
    ISSN 2501-2533 ; 2457-4325
    ISSN (online) 2501-2533
    ISSN 2457-4325
    DOI 10.22336/rjo.2022.41
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The role of vitreous management in the posterior capsule rupture associated with cataract surgery on the protection of the corneal endothelium.

    Milcu, Adina-Iuliana / Istrate, Sînziana Luminița / Ungureanu, Emil / Tătaru, Călin Petru / Munteanu, Mihnea / Borugă, Ovidiu / Palfi Salavat, Mădălina-Casiana / Anghel, Andrei

    Romanian journal of ophthalmology

    2022  Volume 66, Issue 2, Page(s) 132–134

    Abstract: ... ...

    Abstract Introduction
    MeSH term(s) Capsule Opacification ; Cataract ; Cataract Extraction/methods ; Endothelium, Corneal ; Humans ; Phacoemulsification ; Prospective Studies ; Vitrectomy/methods
    Language English
    Publishing date 2022-08-02
    Publishing country Romania
    Document type Journal Article
    ZDB-ID 2842202-8
    ISSN 2501-2533 ; 2457-4325
    ISSN (online) 2501-2533
    ISSN 2457-4325
    DOI 10.22336/rjo.2022.26
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Aflibercept Versus Bevacizumab as First-Line Therapy in Age-Related Macular Degeneration.

    Palfi Salavat, Mădălina-Casiana / Șeclăman, Edward Paul / Mușat, Andreea-Alexandra / Borugă, Mădălina / Patoni, Cristina / Popescu, Marius-Nicolae / Teodorescu, Oana Elena / Mușat, Ovidiu / Popescu Patoni, Stella Ioana

    Current health sciences journal

    2023  Volume 49, Issue 4, Page(s) 503–509

    Abstract: Background: AMD (age-related macular degeneration) is the main cause of central vision loss in the population over 60 years old. AMD does not affect peripheral vision and complete blindness does not occur, instead, central vision is affected both for ... ...

    Abstract Background: AMD (age-related macular degeneration) is the main cause of central vision loss in the population over 60 years old. AMD does not affect peripheral vision and complete blindness does not occur, instead, central vision is affected both for distance and for near. The purpose of this study is to evaluate the neovascular form of AMD treatment and compare ocular and systemic effects after intravitreal injection of aflibercept, respectively after bevacizumab when administered in comparable dosages and regimens. We conducted a retrospective, single-center study from June 2021 to December 2022 and enrolled 20 patients with neovascular AMD who had not received any prior treatment for this condition. We randomly assigned them to two groups of 10: group one received aflibercept and group two received bevacizumab as intravitreal injections under aseptic conditions. We excluded 2 patients who did not meet the criteria and ended up with two groups of 9 patients who received monocular treatment. We gave the patients 3 monthly injections of anti-VEGF agent and followed them up at 1 month, 3 months, and 9 months after the treatment. We assessed their visual acuity, intraocular pressure and OCT appearance at each follow-up visit. The primary outcome was visual acuity. All 18 patients included in the study reported an improvement in visual acuity after the intervention. When comparing the two anti-VEGF agents, data revealed the effect of aflibercept was prompter and more long-lasting. Areas of retinal ischemia appeared in both cases. However, they were observed faster in the case of patients treated with aflibercept. Thus, neovascular AMD is a disease that occurs with age, it can be early detected by OCT and slowed the progression to central blindness with intravitreal treatment.
    Language English
    Publishing date 2023-12-29
    Publishing country Romania
    Document type Journal Article
    ZDB-ID 2708703-7
    ISSN 2069-4032 ; 2067-0656
    ISSN (online) 2069-4032
    ISSN 2067-0656
    DOI 10.12865/CHSJ.49.04.4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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