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  1. Article ; Online: Medicinal cannabis: new challenges for the anesthesiologist.

    Saffier, Igor P / Palmeira, Claudia C A

    Brazilian journal of anesthesiology (Elsevier)

    2021  Volume 71, Issue 3, Page(s) 306–307

    MeSH term(s) Anesthesiologists ; Humans ; Medical Marijuana
    Chemical Substances Medical Marijuana
    Language English
    Publishing date 2021-04-27
    Publishing country Brazil
    Document type Letter
    ISSN 2352-2291
    ISSN (online) 2352-2291
    DOI 10.1016/j.bjane.2021.02.056
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Intraoperative use of methadone improves control of postoperative pain in morbidly obese patients

    Machado FC / Palmeira CCA / Torres JNL / Vieira JE / Ashmawi HA

    Journal of Pain Research, Vol Volume 11, Pp 2123-

    a randomized controlled study

    2018  Volume 2129

    Abstract: Felipe Chiodini Machado, Claudia Carneiro de Araújo Palmeira, João Nathanael Lima Torres, Joaquim Edson Vieira, Hazem Adel Ashmawi Anesthesiology Department, hcFMUsP, Universidade de São Paulo, São Paulo, Brazil Objectives: Surgical patients still ... ...

    Abstract Felipe Chiodini Machado, Claudia Carneiro de Araújo Palmeira, João Nathanael Lima Torres, Joaquim Edson Vieira, Hazem Adel Ashmawi Anesthesiology Department, hcFMUsP, Universidade de São Paulo, São Paulo, Brazil Objectives: Surgical patients still commonly experience postoperative pain. With the increasing prevalence of obesity, there is a growing demand for surgical procedures by this population. Intraoperative use of methadone has not been well assessed in this population. Materials and methods: Patients with a body mass index of 35 kg/m2 or more undergoing bariatric surgery were randomly assigned to receive either fentanyl (group F) or methadone (group M) in anesthesia induction and maintenance. The primary outcome was morphine consumption during the first 24 hours after surgery through a patient-controlled analgesia device. Secondary outcomes were pain scores at rest and while coughing, opioid related side effects, and patient satisfaction. The patients were also evaluated 3 months after surgery for the presence of pain, dysesthesia, or paresthesia at surgical site. Results: Postoperative morphine consumption was significantly higher for patients receiving fentanyl than methadone during the postoperative period at 2 hours (mean difference [MD] 6.4 mg; 95% CI 3.1–9.6; P<0.001), 2–6 hours (MD 11.4 mg; 95% CI 6.5–16.2; P<0.001), 6–24 hours (MD 10.4 mg; 95% CI 5.0–15.7; P<0.001), and 24–48 hours (MD 14.5 mg; 95% CI 3.9–25.1; P=0.01). Patients from group F had higher pain scores until 24 hours postoperatively, higher incidence of nausea and vomiting, lower satisfaction, and more evoked pain at surgical scar at the 3-month postoperative evaluation than group M. Conclusion: Intraoperative methadone can safely lower postoperative opioid consumption and improve postoperative pain scores compared with fentanyl in morbidly obese patients. Keywords: postoperative pain, bariatric surgery, acute pain, postoperative pain, methadone
    Keywords Methadone ; Bariatric surgery ; Acute pain ; Postoperative pain ; Medicine (General) ; R5-920
    Language English
    Publishing date 2018-10-01T00:00:00Z
    Publisher Dove Medical Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    Inter-library loan at ZB MED

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  3. Article: Intraoperative use of methadone improves control of postoperative pain in morbidly obese patients: a randomized controlled study.

    Machado, Felipe Chiodini / Palmeira, Claudia Carneiro de Araújo / Torres, João Nathanael Lima / Vieira, Joaquim Edson / Ashmawi, Hazem Adel

    Journal of pain research

    2018  Volume 11, Page(s) 2123–2129

    Abstract: Objectives: Surgical patients still commonly experience postoperative pain. With the increasing prevalence of obesity, there is a growing demand for surgical procedures by this population. Intraoperative use of methadone has not been well assessed in ... ...

    Abstract Objectives: Surgical patients still commonly experience postoperative pain. With the increasing prevalence of obesity, there is a growing demand for surgical procedures by this population. Intraoperative use of methadone has not been well assessed in this population.
    Materials and methods: Patients with a body mass index of 35 kg/m
    Results: Postoperative morphine consumption was significantly higher for patients receiving fentanyl than methadone during the postoperative period at 2 hours (mean difference [MD] 6.4 mg; 95% CI 3.1-9.6;
    Conclusion: Intraoperative methadone can safely lower postoperative opioid consumption and improve postoperative pain scores compared with fentanyl in morbidly obese patients.
    Language English
    Publishing date 2018-10-02
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2495284-9
    ISSN 1178-7090
    ISSN 1178-7090
    DOI 10.2147/JPR.S172235
    Database MEDical Literature Analysis and Retrieval System OnLINE

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