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Article ; Online: Map-based B

Pan, Jullie W / Terpstra, Melissa J / Moon, Chan-Hong / Hetherington, Hoby P

2023 Volume 36, Issue 12, Page(s) e5021

Abstract: ... While ... ...

Abstract	While B
MeSH term(s)	Humans ; Brain/diagnostic imaging ; Head ; Magnetic Resonance Spectroscopy/methods ; Magnetic Resonance Imaging/methods ; Image Processing, Computer-Assisted/methods
Chemical Substances	benthiocarb (90LN6Y7I7H) ; methyl 3-mercaptopropionimidate (66592-92-5)
Language	English
Publishing date	2023-08-16
Publishing country	England
Document type	Journal Article
ZDB-ID	1000976-0
ISSN	1099-1492 ; 0952-3480
ISSN (online)	1099-1492
ISSN	0952-3480
DOI	10.1002/nbm.5021
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Article ; Online: Fast, regional three-dimensional hybrid (1D-Hadamard 2D-rosette) proton MR spectroscopic imaging in the human temporal lobes.

Tal, Assaf / Zhao, Tiejun / Schirda, Claudiu / Hetherington, Hoby P / Pan, Jullie W / Gonen, Oded

NMR in biomedicine

2021 Volume 34, Issue 6, Page(s) e4507

Abstract: ... ...

Abstract	1
MeSH term(s)	Adult ; Computer Simulation ; Female ; Humans ; Imaging, Three-Dimensional ; Magnetic Resonance Imaging ; Male ; Phantoms, Imaging ; Proton Magnetic Resonance Spectroscopy ; Signal-To-Noise Ratio ; Temporal Lobe/diagnostic imaging ; Young Adult
Language	English
Publishing date	2021-03-23
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	1000976-0
ISSN	1099-1492 ; 0952-3480
ISSN (online)	1099-1492
ISSN	0952-3480
DOI	10.1002/nbm.4507
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Article ; Online: Electromagnetic simulation of a 16-channel head transceiver at 7 T using circuit-spatial optimization.

Li, Xin / Pan, Jullie W / Avdievich, Nikolai I / Hetherington, Hoby P / Rispoli, Joseph V

Magnetic resonance in medicine

2021 Volume 85, Issue 6, Page(s) 3463–3478

Abstract: Purpose: With increased interest in parallel transmission in ultrahigh-field MRI, methods are needed to correctly calculate the S-parameters and complex field maps of the parallel transmission coil. We present S-parameters paired with spatial field ... ...

Abstract	Purpose: With increased interest in parallel transmission in ultrahigh-field MRI, methods are needed to correctly calculate the S-parameters and complex field maps of the parallel transmission coil. We present S-parameters paired with spatial field optimization to fully simulate a double-row 16-element transceiver array for brain MRI at 7 T. Methods: We implemented a closed-form equation of the coil S-parameters and overall spatial Results: As performed with Conclusion: This co-simulation methodology accurately simulates the transceiver, predicting consistent S-parameters, component values, and
MeSH term(s)	Computer Simulation ; Electromagnetic Phenomena ; Equipment Design ; Humans ; Magnetic Resonance Imaging ; Phantoms, Imaging
Language	English
Publishing date	2021-02-03
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	605774-3
ISSN	1522-2594 ; 0740-3194
ISSN (online)	1522-2594
ISSN	0740-3194
DOI	10.1002/mrm.28672
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Article ; Online: Cerebrospinal fluid-suppressed T

Pan, Jullie W / Moon, Chan Hong / Hetherington, Hoby P

Magnetic resonance in medicine

2018 Volume 81, Issue 5, Page(s) 2924–2936

Abstract: Purpose: T: Methods: The strategy uses a driven equilibrium spin-echo preparation within an inversion recovery with multiple 3D gradient-echo imaging blocks. Images are combined using the self-normalization approach, which achieves CSF suppression ... ...

Abstract	Purpose: T Methods: The strategy uses a driven equilibrium spin-echo preparation within an inversion recovery with multiple 3D gradient-echo imaging blocks. Images are combined using the self-normalization approach, which achieves CSF suppression through optimized timing of individual blocks and minimizes sources of variation due to coil receptivity, T Results: The specific absorption rate of the calculated MPFLAGRE sequence is 11.1 ± 0.5 W (n = 5 volunteers), which is 74 ± 2% of the US Food and Drug Administration guidelines. This method acquires both contrasts for CSF suppression with detection of long T Conclusion: As applied with the 8
MeSH term(s)	Algorithms ; Brain/diagnostic imaging ; Cerebrospinal Fluid/diagnostic imaging ; Female ; Humans ; Image Enhancement/methods ; Image Interpretation, Computer-Assisted/methods ; Imaging, Three-Dimensional/methods ; Magnetic Resonance Imaging ; Male ; Signal-To-Noise Ratio ; Whole Body Imaging
Language	English
Publishing date	2018-11-19
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	605774-3
ISSN	1522-2594 ; 0740-3194
ISSN (online)	1522-2594
ISSN	0740-3194
DOI	10.1002/mrm.27598
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Article: Utility of magnetic resonance spectroscopic imaging for human epilepsy.

Pan, Jullie W / Kuzniecky, Ruben I

Quantitative imaging in medicine and surgery

2015 Volume 5, Issue 2, Page(s) 313–322

Abstract: This review discusses the potential utility of broad based use of magnetic resonance (MR) spectroscopic imaging for human epilepsy and seizure localization. The clinical challenges are well known to the epilepsy community, intrinsic in the variability of ...

Abstract	This review discusses the potential utility of broad based use of magnetic resonance (MR) spectroscopic imaging for human epilepsy and seizure localization. The clinical challenges are well known to the epilepsy community, intrinsic in the variability of location, volumetric size and network extent of epileptogenic tissue in individual patients. The technical challenges are also evident, with high performance requirements in multiple steps, including magnet homogeneity, detector performance, sequence design, speed of acquisition in addition to large territory spectral processing. We consider how MR spectroscopy and spectroscopic imaging has been informative for epilepsy thus far, with specific attention to what is measured, the interpretation of such measurements and technical performance challenges. Examples are shown from medial temporal lobe and neocortical epilepsies are considered from 4T, 7T and most recently 3T.
Language	English
Publishing date	2015-03-25
Publishing country	China
Document type	Journal Article ; Review
ZDB-ID	2653586-5
ISSN	2223-4306 ; 2223-4292
ISSN (online)	2223-4306
ISSN	2223-4292
DOI	10.3978/j.issn.2223-4292.2015.01.03
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Article ; Online: Dynamic B

Hetherington, Hoby P / Moon, Chan Hong / Schwerter, Michael / Shah, Nadim Joni / Pan, Jullie W

Magnetic resonance in medicine

2020 Volume 85, Issue 1, Page(s) 531–543

Abstract: Purpose: To describe and implement a strategy for dynamic slice-by-slice and multiband B: Theory: For thin axial slices, spherical harmonic shims can be divided into pairs of shims (z-degenerate and non-z-degenerate) that are spatially degenerate, ... ...

Abstract	Purpose: To describe and implement a strategy for dynamic slice-by-slice and multiband B Theory: For thin axial slices, spherical harmonic shims can be divided into pairs of shims (z-degenerate and non-z-degenerate) that are spatially degenerate, such that only ½ of the shims (non-z-degenerate) are required for single slice optimizations. However, when combined, the pairs of shims can be used to simultaneously generate the same in-plane symmetries but with different amplitudes as a function of their z location. This enables multiband shimming equivalent to that achievable by single slice-by-slice optimization. Methods: All data were acquired at 7T using a spherical harmonic shim insert enabling shimming up through 4th order with two additional 5th order shims (1st-4th+). Dynamic shim updating was achieved using a 10A shim power supply with 2 ms ramps and constrained optimizations to minimize eddy currents. Results: In groups of eight subjects, we demonstrated that: 1) dynamic updating using 1st-4th+ order shims reduced the SD of the B Conclusion: High order spherical harmonics provide substantial improvements over static global shimming and enable dynamic multiband shimming with near equivalent performance to that of dynamic slice-by-slice shimming. This reduces distortion in echo planar imaging.
MeSH term(s)	Brain/diagnostic imaging ; Brain Mapping ; Echo-Planar Imaging ; Humans ; Image Processing, Computer-Assisted ; Magnetic Resonance Imaging
Language	English
Publishing date	2020-08-28
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	605774-3
ISSN	1522-2594 ; 0740-3194
ISSN (online)	1522-2594
ISSN	0740-3194
DOI	10.1002/mrm.28438
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Article: Modelling and B1 Shim Analysis of 16-Element Transceiver Array at 7 T.

Li, Xin / Gong, Haoda / Pan, Jullie W / Hetherington, Hoby P / Rispoli, Joseph V

International Conference on Electromagnetics in Advanced Applications : proceedings : ICEAA. International Conference on Electromagnetics in Advanced Applications

2019 Volume 2019, Page(s) 1291–1295

Abstract: The work examines the workflow of using commercially available software for electromagnetic modelling and validation of a transceiver array coil operating at 298 MHz for magnetic resonance imaging and spectroscopy at 7 T. The coneshaped, tight-fit ... ...

Abstract	The work examines the workflow of using commercially available software for electromagnetic modelling and validation of a transceiver array coil operating at 298 MHz for magnetic resonance imaging and spectroscopy at 7 T. The coneshaped, tight-fit parallel transmit head array consists of two rows with eight loop coils per row and transmits two distinct spatial distributions by means of
Language	English
Publishing date	2019-10-24
Publishing country	United States
Document type	Journal Article
DOI	10.1109/iceaa.2019.8879006
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Article ; Online: MR spectroscopic imaging at 3 T and outcomes in surgical epilepsy.

Pan, Jullie W / Antony, Arun / Tal, Assaf / Yushmanov, Victor / Fong, Joanna / Richardson, Mark / Schirda, Claud / Bagic, Anto / Gonen, Oded / Hetherington, Hoby P

NMR in biomedicine

2021 Volume 34, Issue 6, Page(s) e4492

Abstract: For the spectroscopic assessment of brain disorders that require large-volume coverage, the requirements of RF performance and field homogeneity are high. For epilepsy, this is also challenging given the inter-patient variation in location, severity and ... ...

Abstract	For the spectroscopic assessment of brain disorders that require large-volume coverage, the requirements of RF performance and field homogeneity are high. For epilepsy, this is also challenging given the inter-patient variation in location, severity and subtlety of anatomical identification and its tendency to involve the temporal region. We apply a targeted method to examine the utility of large-volume MR spectroscopic imaging (MRSI) in surgical epilepsy patients, implementing a two-step acquisition, comprised of a 3D acquisition to cover the fronto-parietal regions, and a contiguous parallel two-slice Hadamard-encoded acquisition to cover the temporal-occipital region, both with T
MeSH term(s)	Adult ; Aspartic Acid/analogs & derivatives ; Aspartic Acid/metabolism ; Case-Control Studies ; Epilepsy/diagnostic imaging ; Epilepsy/surgery ; Female ; Gray Matter/diagnostic imaging ; Gray Matter/pathology ; Humans ; Magnetic Resonance Spectroscopy ; Male ; Middle Aged ; Young Adult
Chemical Substances	Aspartic Acid (30KYC7MIAI) ; N-acetylaspartate (997-55-7)
Language	English
Publishing date	2021-03-10
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	1000976-0
ISSN	1099-1492 ; 0952-3480
ISSN (online)	1099-1492
ISSN	0952-3480
DOI	10.1002/nbm.4492
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Article ; Online: Resonant inductive decoupling (RID) for transceiver arrays to compensate for both reactive and resistive components of the mutual impedance.

Avdievich, Nikolai I / Pan, Jullie W / Hetherington, Hoby P

NMR in biomedicine

2013 Volume 26, Issue 11, Page(s) 1547–1554

Abstract: Transceiver surface coil arrays improve transmit performance (B1/√kW) and B1 homogeneity for head imaging up to 9.4 T. To further improve reception performance and parallel imaging, the number of array elements must be increased with a corresponding ... ...

Abstract	Transceiver surface coil arrays improve transmit performance (B1/√kW) and B1 homogeneity for head imaging up to 9.4 T. To further improve reception performance and parallel imaging, the number of array elements must be increased with a corresponding decrease in their size. With a large number of small interacting antennas, decoupling is one of the most challenging aspects in the design and construction of transceiver arrays. Previously described decoupling techniques using geometric overlap, inductive or capacitive decoupling have focused on the elimination of the reactance of the mutual impedance only, which can limit the obtainable decoupling to -10 dB as a result of residual mutual resistance. A novel resonant inductive decoupling (RID) method, which allows compensation for both reactive and resistive components of the mutual impedance between the adjacent surface coils, has been developed and verified experimentally. This method provides an easy way to adjust the decoupling remotely by changing the resonance frequency of the RID circuit through the adjustment of a variable capacitor. As an example, a single-row (1 × 16) 7-T transceiver head array of n = 16 small overlapped surface coils using RID decoupling between adjacent coils was built. In combination with overlapped coils, the RID technique achieved better than -24 dB of decoupling for all adjacent coils.
MeSH term(s)	Electric Impedance ; Equipment Design ; Humans ; Magnetic Resonance Imaging/instrumentation ; Phantoms, Imaging
Language	English
Publishing date	2013-06-18
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	1000976-0
ISSN	1099-1492 ; 0952-3480
ISSN (online)	1099-1492
ISSN	0952-3480
DOI	10.1002/nbm.2989
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Article ; Online: Intracranial monitoring contributes to seizure freedom for temporal lobectomy patients with nonconcordant preoperative data.

Sokolov, Elisaveta / Sisterson, Nathaniel D / Hussein, Helweh / Plummer, Cheryl / Corson, Danielle / Antony, Arun R / Mettenburg, Joseph M / Ghearing, Gena R / Pan, Jullie W / Urban, Alexandra / Bagić, Anto / Richardson, R Mark / Kokkinos, Vasileios

Epilepsia open

2021 Volume 7, Issue 1, Page(s) 36–45

Abstract: Objective: The question of whether a patient with presumed temporal lobe seizures should proceed directly to temporal lobectomy surgery versus undergo intracranial monitoring arises commonly. We evaluate the effect of intracranial monitoring on seizure ... ...

Abstract	Objective: The question of whether a patient with presumed temporal lobe seizures should proceed directly to temporal lobectomy surgery versus undergo intracranial monitoring arises commonly. We evaluate the effect of intracranial monitoring on seizure outcome in a retrospective cohort of consecutive subjects who specifically underwent an anterior temporal lobectomy (ATL) for refractory temporal lobe epilepsy (TLE). Methods: We performed a retrospective analysis of 85 patients with focal refractory TLE who underwent ATL following: (a) intracranial monitoring via craniotomy and subdural/depth electrodes (SDE/DE), (b) intracranial monitoring via stereotactic electroencephalography (sEEG), or (c) no intracranial monitoring (direct ATL-dATL). For each subject, the presurgical primary hypothesis for epileptogenic zone localization was characterized as unilateral TLE, unilateral TLE plus (TLE+), or TLE with bilateral/poor lateralization. Results: At one-year and most recent follow-up, Engel Class I and combined I/II outcomes did not differ significantly between the groups. Outcomes were better in the dATL group compared to the intracranial monitoring groups for lesional cases but were similar in nonlesional cases. Those requiring intracranial monitoring for a hypothesis of TLE+had similar outcomes with either intracranial monitoring approach. sEEG was the only approach used in patients with bilateral or poorly lateralized TLE, resulting in 77.8% of patients seizure-free at last follow-up. Importantly, for 85% of patients undergoing SEEG, recommendation for ATL resulted from modifying the primary hypothesis based on iEEG data. Significance: Our study highlights the value of intracranial monitoring in equalizing seizure outcomes in difficult-to-treat TLE patients undergoing ATL.
MeSH term(s)	Craniotomy ; Freedom ; Humans ; Retrospective Studies ; Seizures/surgery ; Treatment Outcome
Language	English
Publishing date	2021-11-16
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	2470-9239
ISSN (online)	2470-9239
DOI	10.1002/epi4.12483
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