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  1. Article ; Online: Corrigendum to "ANXA2 and Rac1 negatively regulates autophagy and osteogenic differentiation in osteosarcoma cells to confer CDDP resistance" [Biochem. Biophys. Res. Commun. 676 (2023) 198-206].

    Pan, Baolong / Pan, Yanyu / Wang, Shuangneng / Bai, Yingying / Hu, Xuemei / Yang, Yang / Wu, Ling / Liu, Jianping

    Biochemical and biophysical research communications

    2024  Volume 704, Page(s) 149487

    Language English
    Publishing date 2024-02-24
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 205723-2
    ISSN 1090-2104 ; 0006-291X ; 0006-291X
    ISSN (online) 1090-2104 ; 0006-291X
    ISSN 0006-291X
    DOI 10.1016/j.bbrc.2024.149487
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 116: Show issues Location:
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  2. Article: Medium- and High-Entropy Rare Earth Hexaborides with Enhanced Solar Energy Absorption and Infrared Emissivity.

    Wang, Hongye / Pan, Yanyu / Zhang, Jincheng / Wang, Kaixian / Xue, Liyan / Huang, Minzhong / Li, Yazhu / Yang, Fan / Chen, Heng

    Materials (Basel, Switzerland)

    2024  Volume 17, Issue 8

    Abstract: The development of a new generation of solid particle solar receivers (SPSRs) with high solar absorptivity (0.28-2.5 μm) and high infrared emissivity (1-22 μm) is crucial and has attracted much attention for the attainment of the goals of "peak carbon" ... ...

    Abstract The development of a new generation of solid particle solar receivers (SPSRs) with high solar absorptivity (0.28-2.5 μm) and high infrared emissivity (1-22 μm) is crucial and has attracted much attention for the attainment of the goals of "peak carbon" and "carbon neutrality". To achieve the modulation of infrared emission and solar absorptivity, two types of medium- and high-entropy rare-earth hexaboride (ME/HEREB
    Language English
    Publishing date 2024-04-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma17081789
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  3. Article ; Online: ANXA2 and Rac1 negatively regulates autophagy and osteogenic differentiation in osteosarcoma cells to confer CDDP resistance.

    Pan, Baolong / Pan, Yanyu / Wang, Shuangneng / Bai, Yingying / Hu, Xuemei / Yang, Yang / Wu, Ling / Liu, Jianping

    Biochemical and biophysical research communications

    2023  Volume 676, Page(s) 198–206

    Abstract: Background: Cisplatin (CDDP) is a mainstay chemotherapeutic agent for OS treatment, but drug resistance has become a hurdle to limit its clinical effect. Autophagy plays an important role in CDDP resistance in OS, and in the present study we explored ... ...

    Abstract Background: Cisplatin (CDDP) is a mainstay chemotherapeutic agent for OS treatment, but drug resistance has become a hurdle to limit its clinical effect. Autophagy plays an important role in CDDP resistance in OS, and in the present study we explored the role of ANXA2 and Rac1 in dictating CDDP sensitivity in OS cells.
    Methods: ANXA2 and Rac1 expression levels were examined by Western blot and autophagy induction was detected by transmission electron miscroscope (TEM) in the clinical samples and OS cell lines. CDDP resistant cells were established by exposing OS cells to increasing doses of CDDP. The effects of ANXA2 and Rac1 knockdown on CDDP sensitivity were evaluated in the cell and animal models.
    Results: Reduced autophagy was associated with the increased expression of ANXA2 and Rac1 in CDDP resistant OS tumor samples and cells. Autophagy suppression promoted CDDP resistance and inducing autophagy re-sensitized the resistant cells to CDDP treatment in vitro and in vivo. Further, knocking down ANXA2 or Rac1 re-activated autophagy and attenuated CDDP resistance in OS cells. We further demonstrated that CDDP resistant OS cells displayed a poorer osteogenic differentiation state when compared to the parental cell lines, which was significantly reversed by autophagy re-activation and ANXA2 or Rac1 silencing.
    Conclusion: Our findings revealed a complicated interplay of ANXA2/Rac1, autophagy induction, and osteogenic differentiation in dictating CDDP resistance in OS cells, suggesting ANXA2 and Rac1 as promising targets to modulate autophagy and overcome CDDP resistance in OS cells.
    MeSH term(s) Animals ; Cisplatin/pharmacology ; Cisplatin/therapeutic use ; Osteogenesis ; Cell Line, Tumor ; Osteosarcoma/drug therapy ; Osteosarcoma/genetics ; Osteosarcoma/metabolism ; Bone Neoplasms/drug therapy ; Bone Neoplasms/genetics ; Bone Neoplasms/metabolism ; Autophagy ; Drug Resistance, Neoplasm ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Apoptosis
    Chemical Substances Cisplatin (Q20Q21Q62J) ; Antineoplastic Agents
    Language English
    Publishing date 2023-07-03
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 205723-2
    ISSN 1090-2104 ; 0006-291X ; 0006-291X
    ISSN (online) 1090-2104 ; 0006-291X
    ISSN 0006-291X
    DOI 10.1016/j.bbrc.2023.07.006
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  4. Article ; Online: Erratum:

    Liu, Qian / Xue, Lin / Wu, Kui / Fan, Guoyin / Bai, Xiangning / Yang, Xi / Cao, Lijiao / Sun, Hui / Song, Wentao / Pan, Yanyu / Chen, Shengen / Xiong, Yanwen / Chen, Haiying

    International journal of systematic and evolutionary microbiology

    2022  Volume 72, Issue 3

    Language English
    Publishing date 2022-03-22
    Publishing country England
    Document type Journal Article ; Published Erratum
    ZDB-ID 2002336-4
    ISSN 1466-5034 ; 1466-5026
    ISSN (online) 1466-5034
    ISSN 1466-5026
    DOI 10.1099/ijsem.0.005301
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Macrophages are needed in the progression of tuberculosis into lung cancer.

    Li, Jin / Pan, Yanyu / Zhang, Baohua / Chen, Qihuang

    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

    2015  Volume 36, Issue 8, Page(s) 6063–6066

    Abstract: Although the association of tuberculosis (TB) and the development of lung carcinoma (LC) has been acknowledged, the underlying mechanism remains not clarified. Since sustained and repeated local inflammation and tissue remodeling have been suggested to ... ...

    Abstract Although the association of tuberculosis (TB) and the development of lung carcinoma (LC) has been acknowledged, the underlying mechanism remains not clarified. Since sustained and repeated local inflammation and tissue remodeling have been suggested to be responsible for the high incidence of developing CL from TB, we hypothesize that macrophages may play a critical role in the process. To prove it, we induced TB in mice by injection of virulent Mycobacterium tuberculosis (MTB). Then the mice were allotted into two groups. One group received weekly tail vein injection of 20 μg saporin-conjugated antibody against the pan-macrophage surface marker CD11b to eliminate macrophages, while the other group received injection of control IgG in the same frequency. Six months later, the development of LC was determined by histology. We found that the occurrence of LC in TB mice that received macrophage depletion was significantly lower than those in control TB mice without macrophage intervention. These data suggest that macrophages may promote the progression of TB into LC.
    MeSH term(s) Animals ; Antibodies/administration & dosage ; Disease Models, Animal ; Disease Progression ; Humans ; Inflammation/complications ; Inflammation/microbiology ; Inflammation/pathology ; Lung Neoplasms/complications ; Lung Neoplasms/microbiology ; Lung Neoplasms/pathology ; Macrophages/microbiology ; Macrophages/pathology ; Mice ; Mycobacterium tuberculosis/pathogenicity ; Tuberculosis/complications ; Tuberculosis/microbiology ; Tuberculosis/pathology
    Chemical Substances Antibodies
    Language English
    Publishing date 2015-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605825-5
    ISSN 1423-0380 ; 0289-5447 ; 1010-4283
    ISSN (online) 1423-0380
    ISSN 0289-5447 ; 1010-4283
    DOI 10.1007/s13277-015-3283-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1598: Show issues Location:
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  6. Article: Antimicrobial Resistance of Non-O157 Shiga Toxin-Producing

    Pan, Yanyu / Hu, Bin / Bai, Xiangning / Yang, Xi / Cao, Lijiao / Liu, Qian / Sun, Hui / Li, Juan / Zhang, Ji / Jin, Dong / Xiong, Yanwen

    Antibiotics (Basel, Switzerland)

    2021  Volume 10, Issue 1

    Abstract: Non-O157 Shiga toxin- ... ...

    Abstract Non-O157 Shiga toxin-producing
    Language English
    Publishing date 2021-01-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics10010074
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  7. Article ; Online: Nanchangia anserum

    Liu, Qian / Xue, Lin / Wu, Kui / Fan, Guoyin / Bai, Xiangning / Yang, Xi / Cao, Lijiao / Sun, Hui / Song, Wentao / Pan, Yanyu / Chen, Shengen / Xiong, Yanwen / Chen, Haiying

    International journal of systematic and evolutionary microbiology

    2021  Volume 71, Issue 8

    Abstract: Two rod-shaped and Gram-stain-positive bacteria (strains ... ...

    Abstract Two rod-shaped and Gram-stain-positive bacteria (strains C64
    MeSH term(s) Actinomycetaceae/classification ; Actinomycetaceae/isolation & purification ; Animals ; Bacterial Typing Techniques ; Base Composition ; China ; DNA, Bacterial/genetics ; Fatty Acids/chemistry ; Feces/microbiology ; Geese/microbiology ; Phospholipids/chemistry ; Phylogeny ; RNA, Ribosomal, 16S/genetics ; Sequence Analysis, DNA ; Vitamin K 2/chemistry
    Chemical Substances DNA, Bacterial ; Fatty Acids ; Phospholipids ; RNA, Ribosomal, 16S ; Vitamin K 2 (11032-49-8)
    Language English
    Publishing date 2021-08-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 2002336-4
    ISSN 1466-5034 ; 1466-5026
    ISSN (online) 1466-5034
    ISSN 1466-5026
    DOI 10.1099/ijsem.0.004978
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Corynebacterium anserum

    Liu, Qian / Wu, Kui / Fan, Guoyin / Bai, Xiangning / Yang, Xi / Pan, Yanyu / Cao, Lijiao / Song, Wentao / Chen, Shengen / Xiong, Yanwen / Chen, Haiying

    International journal of systematic and evolutionary microbiology

    2020  Volume 71, Issue 2

    Abstract: Two Gram-stain-positive, facultatively aerobic, non-motile and rod- to coccoid-shaped bacterial strains, 23H37- ... ...

    Abstract Two Gram-stain-positive, facultatively aerobic, non-motile and rod- to coccoid-shaped bacterial strains, 23H37-10
    MeSH term(s) Animals ; Bacterial Typing Techniques ; Base Composition ; China ; Corynebacterium/classification ; Corynebacterium/isolation & purification ; DNA, Bacterial/genetics ; Fatty Acids/chemistry ; Feces/microbiology ; Geese/microbiology ; Lakes ; Nucleic Acid Hybridization ; Peptidoglycan/chemistry ; Phospholipids/chemistry ; Phylogeny ; RNA, Ribosomal, 16S/genetics ; Sequence Analysis, DNA ; Vitamin K 2/analogs & derivatives ; Vitamin K 2/chemistry
    Chemical Substances DNA, Bacterial ; Fatty Acids ; Peptidoglycan ; Phospholipids ; RNA, Ribosomal, 16S ; Vitamin K 2 (11032-49-8) ; menaquinone 9 (523-39-7)
    Language English
    Publishing date 2020-12-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 2002336-4
    ISSN 1466-5034 ; 1466-5026
    ISSN (online) 1466-5034
    ISSN 1466-5026
    DOI 10.1099/ijsem.0.004637
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: [Protective effect of silibinin on liver injury induced by antituberculosis drugs].

    Li, Jin / Lin, Wen-feng / Pan, Yan-yu / Zhu, Xiao-yan

    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology

    2010  Volume 18, Issue 5, Page(s) 385–386

    MeSH term(s) Adolescent ; Adult ; Aged ; Antitubercular Agents/adverse effects ; Child ; Female ; Hepatic Insufficiency/chemically induced ; Hepatic Insufficiency/prevention & control ; Humans ; Liver/drug effects ; Liver/physiopathology ; Male ; Middle Aged ; Silymarin/therapeutic use ; Tuberculosis, Pulmonary/drug therapy ; Tuberculosis, Pulmonary/physiopathology ; Young Adult
    Chemical Substances Antitubercular Agents ; Silymarin ; silybin (4RKY41TBTF)
    Language Chinese
    Publishing date 2010-05
    Publishing country China
    Document type Journal Article ; Randomized Controlled Trial
    ISSN 1007-3418
    ISSN 1007-3418
    DOI 10.3760/cma.j.issn.1007-3418.2010.05.019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: [Association of P450-2E1 and GSTM1 genetic polymorphisms with susceptibility to antituberculosis drug-induced hepatotoxicity].

    Wang, Tao / Wang, Wei / Wang, Zhong-yuan / Pan, Yan-yu / Su, Qiong-qiong / He, Lu-xing

    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases

    2009  Volume 32, Issue 8, Page(s) 585–587

    Abstract: Objective: To observe the relationship between the genetic polymorphism of P450-2E1 and the risk for antituberculosis drug-induced hepatotoxicity in a Chinese population.: Methods: Blood samples and clinical data were collected from 85 patients with ... ...

    Abstract Objective: To observe the relationship between the genetic polymorphism of P450-2E1 and the risk for antituberculosis drug-induced hepatotoxicity in a Chinese population.
    Methods: Blood samples and clinical data were collected from 85 patients with antituberculosis drug-induced hepatotoxicity and 100 tuberculosis patients without hepatotoxicity as the control. DNA was extracted from the blood samples, and the frequencies of P450-2E1 RsaI genotypes were analyzed using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). The relationship between the polymorphisms of P450-2E1 RsaI and the antituberculosis drug-induced hepatotoxicity was analyzed. Predisposing factors for antituberculosis drug-induced hepatitis, such as gender, age, and polymorphism of P450-2E1 RsaI were evaluated by using logistic regression analysis.
    Results: The frequencies of the 3 gene types P450-2E1 RsaI c1/c1, c1/c2, and c2/c2 were 75% (64/85), 20% (17/85) and 5% (4/85) respectively in patients with antituberculosis drug-induced hepatotoxicity, and 61% (61/100), 30% (30/100), and 9% (9/100) respectively in the controls. A statistical difference was found between the cases and the controls (chi(2) = 4.284, P < 0.05, OR = 2.016, 95%CI = 1.058 - 3.842). Logistic regression analysis showed that the polymorphism of P450-2E1 RsaI remained a significant independent risk factor for antituberculosis drug-induced hepatotoxicity after adjustment for age, gender and body mass index.
    Conclusion: Polymorphisms of P450-2E1 were found to be significantly associated with the risk of antituberculosis drug-induced hepatotoxicity, and the c1/c1 genotype was one of the risk factors.
    MeSH term(s) Adolescent ; Adult ; Aged ; Antitubercular Agents/adverse effects ; Case-Control Studies ; Chemical and Drug Induced Liver Injury/etiology ; Chemical and Drug Induced Liver Injury/genetics ; Cytochrome P-450 CYP2E1/genetics ; Female ; Gene Frequency ; Humans ; Male ; Middle Aged ; Polymorphism, Restriction Fragment Length ; Young Adult
    Chemical Substances Antitubercular Agents ; Cytochrome P-450 CYP2E1 (EC 1.14.13.-)
    Language Chinese
    Publishing date 2009-08
    Publishing country China
    Document type Journal Article
    ZDB-ID 1027965-9
    ISSN 1001-0939
    ISSN 1001-0939
    Database MEDical Literature Analysis and Retrieval System OnLINE

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