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Article: Concomitant uterus agenesia and Marfan syndrome with systemic sclerosis: A rare case report.

Ebrahimi, Aliasghar / Panahi, Padideh / Tekantapeh, Sepideh Tahsini

2024 Volume 12, Issue 1, Page(s) e8408

Abstract: It seems that the association of two connective tissue disorders, including Marfan syndrome and systemic sclerosis, the first is associated with the loosening of the subcutaneous tissue and the second with its tightening, is a very interesting and ... ...

Abstract	It seems that the association of two connective tissue disorders, including Marfan syndrome and systemic sclerosis, the first is associated with the loosening of the subcutaneous tissue and the second with its tightening, is a very interesting and controversial paradox at the same time and need finding possible genetic etiologies.
Language	English
Publishing date	2024-01-02
Publishing country	England
Document type	Case Reports
ZDB-ID	2740234-4
ISSN	2050-0904
ISSN	2050-0904
DOI	10.1002/ccr3.8408
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Article: Therapeutic anticoagulation in patients with acute pancreatitis and splanchnic vein thrombosis: a best evidence topic.

Redman, Ishtar / Panahi, Pedram / Bananis, Kyriakos / Drymousis, Panagiotis

Annals of medicine and surgery (2012)

2023 Volume 86, Issue 1, Page(s) 271–278

Abstract: A best evidence topic in general surgery was written according to a structured protocol. The clinical question addressed was: in adult patients with splanchnic vein thrombosis in acute pancreatitis, would administration of therapeutic anticoagulation be ... ...

Abstract	A best evidence topic in general surgery was written according to a structured protocol. The clinical question addressed was: in adult patients with splanchnic vein thrombosis in acute pancreatitis, would administration of therapeutic anticoagulation be advisable considering the rates of vessel recanalization and bleeding complications? Four hundred twenty-four papers were found on Ovid Embase and Medline whilst 222 were found on PubMed using the reported literature search. From these, five articles represented the best evidence to the clinical question. The authors, publication dates, countries, patient groups, study outcomes, and results of these papers were tabulated. There were three systematic reviews with meta-analyses, one systematic review without meta-analysis and one randomized, retrospective study. The authors conclude that among patients with splanchnic vein thrombosis in the context of acute pancreatitis, therapeutic anticoagulation improved the rates of recanalization without increasing the risk of bleeding complications. However, there remains a need for randomized studies to address this clinical dilemma to further increase the quality of available evidence.
Language	English
Publishing date	2023-11-16
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2745440-X
ISSN	2049-0801
ISSN	2049-0801
DOI	10.1097/MS9.0000000000001440
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Article ; Online: Studying and simulation of ellipsoidal contact models for application in AFM nano manipulation.

Korayem, M H / Panahi, P / Khaksar, H

Micron (Oxford, England : 1993)

2020 Volume 140, Page(s) 102960

Abstract: Four contact models including Hertz, Jamari, Jeng-Wang and Weng-Tang-Zhou-Zhu were considered. To verify the results of contact mechanics, the indentation depth has been compared with spherical geometry. According to the obtained results, by comparing ... ...

Abstract	Four contact models including Hertz, Jamari, Jeng-Wang and Weng-Tang-Zhou-Zhu were considered. To verify the results of contact mechanics, the indentation depth has been compared with spherical geometry. According to the obtained results, by comparing the spherical and elliptical geometries, the indentation depth for spherical geometry is higher than for the ellipsoidal geometry, due to the existence of eccentricity in elliptical contact models which does not exist in spherical geometry. Among the models, the Jeng-Wang and Weng-Tang-Zhou-Zhu are models that are based on the contact of a particle with the substrate. Based on the existing experimental work, Jeng-Wang is the most suitable model for being applied in particle-substrate contact point. The Hertz model has been developed from crowned cylinder equations in order to be implemented for ellipsoidal geometry, moreover the Jamari model investigates two ellipses in contact with each other. By comparing Jeng-Wang and Weng-Tang-Zhou-Zhu models it is obvious that Jeng-Wang has the highest indentation depth while for the Weng-Tang-Zhou-Zhu model it is the lowest. These trends happen for two contact points. Also four materials are compared, among which graphite and chromium have the highest and the lowest indentation depths, respectively. Finally based on the obtained results Jeng-Wang and Jamari are the most suitable contact models that can be implemented in the manipulation of ellipsoidal nanoparticles.
Language	English
Publishing date	2020-10-28
Publishing country	England
Document type	Journal Article
ZDB-ID	207808-9
ISSN	1878-4291 ; 0047-7206 ; 0968-4328
ISSN (online)	1878-4291
ISSN	0047-7206 ; 0968-4328
DOI	10.1016/j.micron.2020.102960
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Article: Postoperative packing of perianal abscesses following incision and drainage.

Redman, Ishtar A / Panahi, Pedram / Gill, Moneet / Drymousis, Panagiotis

British journal of hospital medicine (London, England : 2005)

2023 Volume 84, Issue 11, Page(s) 1–6

Abstract: A best evidence topic in general surgery was written according to a structured protocol, to address the question: in adult patients with perianal abscesses, should postoperative wound packing be undertaken considering the rates of pain experienced, wound ...

Abstract	A best evidence topic in general surgery was written according to a structured protocol, to address the question: in adult patients with perianal abscesses, should postoperative wound packing be undertaken considering the rates of pain experienced, wound healing and abscess recurrence? The literature search identified 159 papers on Ovid, Embase and Medline and 48 on PubMed. These were independently screened, and three articles were included in this review as these offered the best information to answer the question. One was a systematic review without meta-analysis, one was a randomised controlled trial and one was a multicentre observational study. Review of these articles led the authors to conclude that routine postoperative packing of perianal abscesses following incision and drainage is costly, associated with increased pain and confers no protection against recurrence of abscesses or formation of fistulae.
MeSH term(s)	Adult ; Humans ; Abscess/surgery ; Drainage ; Multicenter Studies as Topic ; Observational Studies as Topic ; Pain ; Postoperative Period ; Randomized Controlled Trials as Topic ; Skin Diseases
Language	English
Publishing date	2023-11-27
Publishing country	England
Document type	Journal Article ; Review
ISSN	1750-8460
ISSN	1750-8460
DOI	10.12968/hmed.2023.0308
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Article: Pelvic arteriovenous malformation (AVM) with recurrent hematuria: A case report.

Nazari, Iraj / Zargar, Mohammad Amin / Panahi, Pegah / Alavi, Seyed Mohammad Amin

International journal of surgery case reports

2023 Volume 110, Page(s) 108701

Abstract: Introduction: Arteriovenous malformation (AVM) leads to a direct connection between arterial and venous networks, in which capillary branches are not involved. Pelvic AVM is a benign and rare condition causing severe pain, hematuria, and rectal or ... ...

Abstract	Introduction: Arteriovenous malformation (AVM) leads to a direct connection between arterial and venous networks, in which capillary branches are not involved. Pelvic AVM is a benign and rare condition causing severe pain, hematuria, and rectal or vaginal bleeding. Case presentation: A 36-year-old woman presented with five months history of hematuria. Her medical history was unremarkable, and laboratory findings were all within normal ranges. Abdominopelvic computed tomography (CT) scan revealed a vascular mass in the left lateral pelvis that extended to the bladder neck and was suggestive of an AVM. The patient underwent a laparotomy for the resection of AVM. The first angiography revealed an AVM in the left internal iliac artery. The patient underwent embolization with coil and gel foam. The second angiography revealed complete obstruction of the left internal iliac artery due to multiple coils and AVM of the right internal iliac artery (RIIA), embolized with glue and lipiodol. A week later, venography revealed another left iliac vein malformation embolized with foam sclerotherapy. Forty days later, the third angiography revealed another AVM in the right iliac artery, embolized with three vials of polyvinyl alcohol (PVA). Following two months of follow-up, the symptoms did not return. Discussion: The present study reported a rare case of recurrent pelvic AVM causing painless hematuria in a female patient. The lesion was treated with several angioembolization sessions. Conclusion: Angioembolization is one of the main therapeutic options for AVM. Appropriate material should be precisely chosen for AVM embolization regarding the AVM's location, size, and condition.
Language	English
Publishing date	2023-08-22
Publishing country	Netherlands
Document type	Case Reports
ISSN	2210-2612
ISSN	2210-2612
DOI	10.1016/j.ijscr.2023.108701
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Article ; Online: Early Vitrectomy for Endophthalmitis: Are EVS Guidelines Still Valid?

Panahi, Parsa / Mirzakouchaki-Borujeni, Nasser / Pourdakan, Omid / Arévalo, J Fernando

Ophthalmic research

2023 Volume 66, Issue 1, Page(s) 1318–1326

Abstract: Background: Endophthalmitis, a potentially sight-threatening condition, remains a challenge for ophthalmologists worldwide. The endophthalmitis vitrectomy study (EVS) conducted in 1995 compared vitrectomy and intravitreal antibiotic injections to ... ...

Abstract	Background: Endophthalmitis, a potentially sight-threatening condition, remains a challenge for ophthalmologists worldwide. The endophthalmitis vitrectomy study (EVS) conducted in 1995 compared vitrectomy and intravitreal antibiotic injections to intravitreal antibiotic injections alone for acute post-cataract surgery and secondary intraocular lens endophthalmitis, setting treatment guidelines. However, the landscape of clinical practice has evolved considerably since then, raising questions about the applicability of EVS recommendations today. Summary: Recent studies have proposed that early and complete vitrectomy (CEVE) could potentially be an effective approach for managing endophthalmitis cases, irrespective of the initial visual acuity. However, it is important to note that the level of rigor in these recent studies may not match that of the EVS study, and as such, this assertion should be considered with caution. Furthermore, the EVS study exclusively focused on post-cataract surgery cases, leaving other endophthalmitis types, like post-intravitreal injection and post-traumatic endophthalmitis, without standardized treatment guidelines. Research exploring the role of early vitrectomy in these contexts yields mixed results, emphasizing the need for further investigation and well-designed prospective trials. Endogenous endophthalmitis, originating from systemic infections, adds complexity to the scenario. While early vitrectomy shows promise in specific cases, conflicting evidence necessitates comprehensive research. Key messages: This review underscores the necessity for tailored treatment strategies, supporting early vitrectomy when clinically indicated, and advocating for prospective trials to clarify its role in diverse endophthalmitis scenarios. As surgical techniques and antimicrobial therapies continue to advance, reevaluating treatment paradigms becomes crucial to enhance patient outcomes and protect ocular health.
MeSH term(s)	Humans ; Vitrectomy ; Anti-Bacterial Agents/therapeutic use ; Prospective Studies ; Eye Infections, Bacterial/therapy ; Eye Infections, Bacterial/drug therapy ; Endophthalmitis/diagnosis ; Endophthalmitis/drug therapy ; Cataract ; Retrospective Studies ; Postoperative Complications/drug therapy
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2023-10-19
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	205708-6
ISSN	1423-0259 ; 0030-3747
ISSN (online)	1423-0259
ISSN	0030-3747
DOI	10.1159/000534650
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Article ; Online: Biometry and intraocular power calculation using a swept-source optical coherence tomography: A repeatability and agreement study.

Hashemi, Hassan / Miraftab, Mohammad / Panahi, Parsa / Asgari, Soheila

Indian journal of ophthalmology

2022 Volume 70, Issue 8, Page(s) 2845–2850

Abstract: Purpose: To evaluate the repeatability of biometry and intraocular lens (IOL) power using Galilei G6 and to determine the agreement of its measurements with those of IOL Master 700 and IOL Master 500.: Methods: Hundred mature cataract eyes were ... ...

Abstract	Purpose: To evaluate the repeatability of biometry and intraocular lens (IOL) power using Galilei G6 and to determine the agreement of its measurements with those of IOL Master 700 and IOL Master 500. Methods: Hundred mature cataract eyes were examined twice with Galilei G6 and the results were compared with those of other two devices. Axial length (AL), minimum (K1), maximum (K2), and mean keratometry, anterior chamber depth (ACD), white-to-white (WTW) diameter, lens thickness (LT), and the calculated IOL power were the studied parameters. The correlation coefficient, within-subject standard deviation (Sw), Bland-Altman method, and 95% limits of agreement (LoA) were used for statistical analysis. Results: The intraclass correlation coefficient (ICC) was above 0.9 for all indices, and the LoA ranged from a minimum of 0.08 mm for AL to a maximum of 0.50 D for K1. Sw also ranged between a minimum of 0.02 for AL, ACD, and WTW and a maximum of 0.13 for K1. In the Galilei G6-IOL Master 700 pair, the narrowest and widest LoA were calculated for AL (0.07 mm) and K2 (0.49 D), respectively. In the Galilei G6-IOL Master 500 pair, the narrowest and widest widths of LoA were calculated for AL (0.17 mm) and K2 (0.92 D), respectively. In the first pair, the LoA of IOL power (0.57 D) were the best for Haigis formula and in the second pair, the best agreement (LoA: 0.35 D) was observed for Holladay-1. Conclusion: Galilei G6 provided repeatable biometric measurements. The agreement between biometry and IOL power calculation was better in the Galilei G6-IOL Master 700 pair compared to the Galilei G6-IOL Master 500.
MeSH term(s)	Axial Length, Eye ; Biometry/methods ; Humans ; Lenses, Intraocular ; Reproducibility of Results ; Tomography, Optical Coherence/methods
Language	English
Publishing date	2022-08-01
Publishing country	India
Document type	Journal Article
ZDB-ID	187392-1
ISSN	1998-3689 ; 0301-4738
ISSN (online)	1998-3689
ISSN	0301-4738
DOI	10.4103/ijo.IJO_249_22
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Article ; Online: Digoxin as a glycosylated steroid-like therapeutic drug: Recent advances in the clinical pharmacology and bioassays of pharmaceutical compounds.

Pashazadeh-Panahi, Paria / Hasanzadeh, Mohammad

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

2020 Volume 123, Page(s) 109813

Abstract: Digoxin is cardiac glycosylated steroid like drug which is the fifth most commonly prescribed in US. Since the health of human population is largely determined by pharmacy they utilized, toxicity and side effects of pharmaceutics can put the safety of ... ...

Abstract	Digoxin is cardiac glycosylated steroid like drug which is the fifth most commonly prescribed in US. Since the health of human population is largely determined by pharmacy they utilized, toxicity and side effects of pharmaceutics can put the safety of people in jeopardy and lead to some devastating impacts. Therefore, it is essential to detect and monitor small molecules like digoxin more meticulously. Although digoxin has positive inotropic and batmotropic impact on heart muscle, it has also negative chronotropic and dromotropic effect. The prescription dose of this drug is 1-2 ng/ml and more than 2.8 ng/ml of this medication cause toxicity. Hence, there is small variation between therapeutic and toxic dosage of digoxin. Abundant conventional methods have been introduced for digoxin monitoring such Liquid chromatography (LC), LC-MS, HPLC. However, they suffer expensive equipment, long lasting procedure and high limit of detection. Hence, various advance immunosorbent, biosensors and aptasensors have been introduced. The purpose of this review is limited to pointing convention methods drawbacks and introducing novel digoxin enzyme-linked or non-enzymatic immunosorbent assays, and biosensors paying special attention to their basic strategies and detection abilities. Future trends in Bio and immune sensors used for onset monitoring and detection of digoxin are also highlighted.
MeSH term(s)	Biological Assay ; Digoxin/pharmacology ; Digoxin/therapeutic use ; Glycosylation ; Humans ; Pharmaceutical Preparations/analysis ; Pharmacology, Clinical/trends ; Steroids/pharmacology ; Steroids/therapeutic use
Chemical Substances	Pharmaceutical Preparations ; Steroids ; Digoxin (73K4184T59)
Language	English
Publishing date	2020-01-07
Publishing country	France
Document type	Journal Article ; Review
ZDB-ID	392415-4
ISSN	1950-6007 ; 0753-3322 ; 0300-0893
ISSN (online)	1950-6007
ISSN	0753-3322 ; 0300-0893
DOI	10.1016/j.biopha.2020.109813
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Article: Long-Term Results of Laser In Situ Keratomileusis in Myopic Patients with Topographic Indices outside Suggested Ranges.

Hashemi, Hassan / Mehravaran, Shiva / Panahi, Parsa / Abdollahinia, Tahereh / Asgari, Soheila

Ophthalmology and therapy

2022 Volume 11, Issue 6, Page(s) 2285–2295

Abstract: Introduction: To investigate the long-term results of laser in situ keratomileusis (LASIK) in patients with one or more topographic indices outside the suggested range preoperatively.: Methods: Patients who had conventional or femtosecond laser- ... ...

Abstract	Introduction: To investigate the long-term results of laser in situ keratomileusis (LASIK) in patients with one or more topographic indices outside the suggested range preoperatively. Methods: Patients who had conventional or femtosecond laser-assisted LASIK for myopia correction between 2011 and 2015, and had at least one preoperative corneal topographic index outside the suggested range were contacted for a follow-up examination. Ranges were based on the cutoffs suggested for subclinical keratoconus: thinnest pachymetry (TP) < 497.50 µm, maximum keratometry (Kmax) > 47.20 D, maximum 8 mm best-fit-sphere anterior elevation (MaxAE) > 9.50 µm, maximum 8 mm best-fit-sphere posterior elevation (MaxPE) > 20.50 µm, and Belin/Ambrósio enhanced ectasia display-total deviation (BAD-D) > 1.60. Results: Two hundred thirty patients (377 eyes) were enrolled; their mean age at baseline and at follow-up was 30.78 ± 8.16 and 9.06 ± 1.91 years, respectively. Mean ± SD was 484.36 ± 11.49 for TP (n = 133), 48.17 ± 0.83 for Kmax (n = 133), 16.33 ± 5.39 for MaxAE (n = 35), 27.87 ± 7.86 for MaxPE (n = 34), and 1.97 ± 0.36 for BAD-D (n = 162). Post-LASIK and suspected ectasia was found in one (0.26%) and two (0.53%) eyes, respectively. In the remaining 374, the efficacy and safety indices were 0.96 ± 0.14 and 1.01 ± 0.08, respectively. Uncorrected distance visual acuity (UDVA) was not reduced in any eyes, and corrected distance visual acuity (CDVA) was reduced one line in 1.9% of the cases; 79.9% of the cases were emmetropic. The long-term changes in UDVA, CDVA, and spherical equivalent were not different between groups with one, two, or three out-of-range topographic indices (all P > 0.05). Conclusion: A single out-of-range topographic index is not a strong predictor for postoperative complications, and one should consider the combination of topographic and clinical findings, or the pattern they create in tandem. Developing a scoring system that would take a combination of indices and topographic patterns may help improve the predictive accuracy of these indices.
Language	English
Publishing date	2022-10-12
Publishing country	England
Document type	Journal Article
ISSN	2193-8245
ISSN	2193-8245
DOI	10.1007/s40123-022-00589-6
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Article ; Online: Revolution in biomedicine using emerging of picomaterials: A breakthrough on the future of medical diagnosis and therapy.

Pashazadeh-Panahi, Paria / Hasanzadeh, Mohammad

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

2019 Volume 120, Page(s) 109484

Abstract: Biomedicine is inseparable part of medicine that play vital role in modern medical progress. Bioimaging, smart drug delivery, safe cancer therapy and personalized medicine are some important properties of this science. Pico technology as a next frontier ... ...

Abstract	Biomedicine is inseparable part of medicine that play vital role in modern medical progress. Bioimaging, smart drug delivery, safe cancer therapy and personalized medicine are some important properties of this science. Pico technology as a next frontier in a scientific filed will revolutionized the scientist world ubiquitously. Extraordinary abilities of pico-particles will overcome convention obstacles and reveal spectacular impact on various scientific fields as well as biomedicine. Fabrication of pico-scale particles and developing pico-technology will be a breakthrough in biomedicine. Graphene Quantum Dots (GQDs) with the particle size of 1-5 nm are highly potential particles with an ability of converting to small molecules. Therefore, we hypothesis emerging of pico-technology based on graphene quantum dots on the future research and development. Therefore, GQDs will be applied as advanced Pico-materials instead of nanomaterials in the future biomedicine and healthcare studies.
MeSH term(s)	Animals ; Biocompatible Materials/chemistry ; Drug Delivery Systems/methods ; Graphite/chemistry ; Humans ; Nanostructures/chemistry ; Particle Size ; Quantum Dots/chemistry
Chemical Substances	Biocompatible Materials ; Graphite (7782-42-5)
Language	English
Publishing date	2019-09-28
Publishing country	France
Document type	Journal Article ; Review
ZDB-ID	392415-4
ISSN	1950-6007 ; 0753-3322 ; 0300-0893
ISSN (online)	1950-6007
ISSN	0753-3322 ; 0300-0893
DOI	10.1016/j.biopha.2019.109484
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