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  1. Book ; Online ; E-Book: Delirium

    Hughes, Christopher G. / Pandharipande, Pratik / Ely, Eugene Wesley

    acute brain dysfunction in the critically ill

    2020  

    Author's details Christopher G. Hughes, Pratik P. Pandharipande, E. Wesley Ely editors
    Keywords Intensive / Critical Care Medicine ; Anesthesiology ; Critical care medicine
    Subject code 616.028
    Language English
    Size 1 Online-Ressource (xiii, 237 Seiten), Illustrationen, Diagramme
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT030640369
    ISBN 978-3-030-25751-4 ; 9783030257507 ; 3-030-25751-7 ; 3030257509
    DOI 10.1007/978-3-030-25751-4
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book: Creating and implementing the 2013 ICU pain, agitation, and delirium guidelines for adult ICU patients

    Barr, Juliana / Pandharipande, Pratik

    (Critical care medicine ; 41,9, Suppl.)

    2013  

    Author's details guest ed.: Juliana Barr and Pratik P. Pandharipande
    Series title Critical care medicine ; 41,9, Suppl.
    Collection
    Language English
    Size S145 S.
    Publisher Wolters Kluwer Health/Lippincott Williams & Wilkins
    Publishing place Hagerstown, MD
    Publishing country United States
    Document type Book
    HBZ-ID HT017797674
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 1261 -41,9,Suppl.- not available for loan Zeitschriften-Lesesaal

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  3. Book: Sedation and analgesia in the ICU

    Pandharipande, Pratik

    pharmacology, protocolization, and clinical consequences

    (Critical care clinics ; 25,3)

    2009  

    Author's details guest ed. Pratik Pandharipande
    Series title Critical care clinics ; 25,3
    Collection
    Language English
    Size XVI S., S. 432 - 635 : Ill., graph. Darst.
    Publisher Saunders
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT016033323
    ISBN 1-4377-1203-7 ; 978-1-4377-1203-2
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    Se 990 -25,3- verfügbar in Königswinter Königswinter

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  4. Article ; Online: Early mobilisation during critical illness: good for the body and brain.

    Girard, Timothy D / Pandharipande, Pratik P

    The Lancet. Respiratory medicine

    2023  Volume 11, Issue 6, Page(s) 500–502

    MeSH term(s) Humans ; Early Ambulation ; Critical Illness/therapy ; Brain ; Intensive Care Units
    Language English
    Publishing date 2023-01-25
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2686754-0
    ISSN 2213-2619 ; 2213-2600
    ISSN (online) 2213-2619
    ISSN 2213-2600
    DOI 10.1016/S2213-2600(23)00011-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 7041: Show issues Location:
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  5. Article ; Online: Do Our Sedation Practices Contribute to Increased Mortality in Coronavirus Disease 2019-Related Acute Respiratory Distress Syndrome?

    Devlin, John W / Pandharipande, Pratik P

    Critical care medicine

    2021  Volume 49, Issue 9, Page(s) 1579–1582

    MeSH term(s) COVID-19 ; Humans ; Respiration, Artificial ; Respiratory Distress Syndrome ; SARS-CoV-2
    Language English
    Publishing date 2021-05-12
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 197890-1
    ISSN 1530-0293 ; 0090-3493
    ISSN (online) 1530-0293
    ISSN 0090-3493
    DOI 10.1097/CCM.0000000000005094
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book: Sedation and analgesia in the ICU

    Pandharipande, Pratik / Ely, Eugene Wesley

    pharmacology, protocolization, and clinical consequences

    (Anesthesiology clinics ; 29,4)

    2011  

    Author's details guest ed. Pratik P. Pandharipande ; E. Wesley Ely
    Series title Anesthesiology clinics ; 29,4
    Collection
    Language English
    Size XVI S., S. 567 - 773 : Ill.
    Publisher Saunders an imprint of Elsevier
    Publishing place Philadelphia, PA
    Publishing country United States
    Document type Book
    HBZ-ID HT017086548
    ISBN 978-1-4557-3360-6 ; 1-4557-3360-1
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    Se 904 -29,4- verfügbar in Königswinter Königswinter

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  7. Article ; Online: Baseline Vulnerabilities May Play a Larger Role than Depth of Anesthesia or Sedation in Postoperative Delirium.

    Pandharipande, Pratik P / Whitlock, Elizabeth L / Hughes, Christopher G

    Anesthesiology

    2021  Volume 135, Issue 6, Page(s) 940–942

    MeSH term(s) Anesthesia ; Delirium ; Humans
    Language English
    Publishing date 2021-11-03
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 269-0
    ISSN 1528-1175 ; 0003-3022
    ISSN (online) 1528-1175
    ISSN 0003-3022
    DOI 10.1097/ALN.0000000000004039
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 199: Show issues

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  8. Article ; Online: The Conundrum of Pain, Opiate Use, and Delirium: Analgosedation or Analgesia-First Approach?

    Hayhurst, Christina J / Hughes, Christopher G / Pandharipande, Pratik P

    American journal of respiratory and critical care medicine

    2021  Volume 204, Issue 5, Page(s) 502–503

    MeSH term(s) Analgesia ; Delirium ; Humans ; Opiate Alkaloids ; Pain ; Pain Management
    Chemical Substances Opiate Alkaloids
    Language English
    Publishing date 2021-05-06
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202104-0968ED
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Data-derived subtypes of delirium during critical illness.

    Potter, Kelly M / Kennedy, Jason N / Onyemekwu, Chukwudi / Prendergast, Niall T / Pandharipande, Pratik P / Ely, E Wesley / Seymour, Christopher / Girard, Timothy D

    EBioMedicine

    2024  Volume 100, Page(s) 104942

    Abstract: Background: To understand delirium heterogeneity, prior work relied on psychomotor symptoms or risk factors to identify subtypes. Data-driven approaches have used machine learning to identify biologically plausible, treatment-responsive subtypes of ... ...

    Abstract Background: To understand delirium heterogeneity, prior work relied on psychomotor symptoms or risk factors to identify subtypes. Data-driven approaches have used machine learning to identify biologically plausible, treatment-responsive subtypes of other acute illnesses but have not been used to examine delirium.
    Methods: We conducted a secondary analysis of a large, multicenter prospective cohort study involving adults in medical or surgical ICUs with respiratory failure or shock who experienced delirium per the Confusion Assessment Method for the ICU. We used data collected before delirium diagnosis in an unsupervised latent class model to identify delirium subtypes and then compared demographics, clinical characteristics, and outcomes between subtypes in the final model.
    Findings: The 731 patients who developed delirium during critical illness had a median age of 63 [IQR, 54-72] years, a median Sequential Organ Failure Assessment score of 8.0 [6.0-11.0] and 613 [83.4%] were mechanically ventilated at delirium identification. A four-class model best fit the data with 50% of patients in subtype (ST) 1, 18% in subtype 2, 17% in subtype 3, and 14% in subtype 4. Subtype 2-which had more shock and kidney impairment-had the highest mortality (33% [ST2] vs. 17% [ST1], 25% [ST3], and 17% [ST4], p = 0.003). Subtype 4-which received more benzodiazepines and opioids-had the longest duration of delirium (6 days [ST4] vs. 3 [ST1], 4 [ST2], and 3 days [ST3], p < 0.001) and coma (4 days [ST4] vs. 2 [ST1], 1 [ST2], and 2 days [ST3], p < 0.001). Each of the four data-derived delirium subtypes was observed within previously identified psychomotor and risk factor-based delirium subtypes. Clinically significant cognitive impairment affected all subtypes at follow-up, but its severity did not differ by subtype (3-month, p = 0.26; 12-month, p = 0.80).
    Interpretation: The four data-derived delirium subtypes identified in this study should now be validated in independent cohorts, examined for differential treatment effects in trials, and inform mechanistic work evaluating treatment targets.
    Funding: National Institutes of Health (T32HL007820, R01AG027472).
    MeSH term(s) Adult ; Humans ; Middle Aged ; Aged ; Delirium/diagnosis ; Delirium/etiology ; Prospective Studies ; Critical Illness ; Interleukin-1 Receptor-Like 1 Protein ; Cognitive Dysfunction/complications
    Chemical Substances Interleukin-1 Receptor-Like 1 Protein
    Language English
    Publishing date 2024-01-01
    Publishing country Netherlands
    Document type Multicenter Study ; Journal Article
    ZDB-ID 2851331-9
    ISSN 2352-3964
    ISSN (online) 2352-3964
    DOI 10.1016/j.ebiom.2023.104942
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: In Response.

    Kingeter, Adam J / Pandharipande, Pratik P

    Anesthesia and analgesia

    2018  Volume 129, Issue 2, Page(s) e60

    MeSH term(s) Academic Medical Centers ; Awareness ; Intensive Care Units ; Surveys and Questionnaires
    Language English
    Publishing date 2018-10-09
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ANE.0000000000003855
    Database MEDical Literature Analysis and Retrieval System OnLINE

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