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  1. Article ; Online: Comparative Study of the Pattern of Dyslipidaemia among Urban and Rural Type2 Diabetes Mellitus Population Attending a Tertiary Care Hospital in Eastern Odisha, India

    Shubhransu Patro / Pankaj Kumar Khora / Swastik Acharya / Anshuman Sarangi

    National Journal of Laboratory Medicine, Vol 9, Iss 3, Pp 10-

    2020  Volume 14

    Abstract: Introduction: Patients with type 2 diabetes mellitus have increased incidence of obesity and are prone to dyslipidaemia which in turn is the key ingredient of Cardiovascular Disease (CVD). The lifestyle, environment and eating habits significantly vary ... ...

    Abstract Introduction: Patients with type 2 diabetes mellitus have increased incidence of obesity and are prone to dyslipidaemia which in turn is the key ingredient of Cardiovascular Disease (CVD). The lifestyle, environment and eating habits significantly vary in urban industrialised areas compared to rural countryside in the same ethnic group. Aim: To compare the pattern of dyslipidaemia among urban and rural type 2 diabetes mellitus population attending a diabetes follow-up clinic in a tertiary care hospital in eastern Odisha. Materials and Methods: The cross-sectional study included patients who attended the diabetes follow-up clinic from July 2017 to December 2017 and included adults (≥18 years) suffering from type 2 diabetes. Type 2 diabetics, 300 each from the urban and rural countryside were included in the study. Sociodemographic characteristics, medical history and laboratory investigations like fasting and Postprandial Blood Sugar (PPBS), lipid parameters and HbA1c were recorded. Anthropometric measurements like height, weight, waist circumference and blood pressure were measured. The laboratory values were calculated as mean±standard deviation and correlation analysis with the Pearson coefficient. Z-test was used to compare data at 95% confidence level. Results: Hypertension was detected in 71% of patients in the urban study sample compared to 34.3% in rural. Obesity was prevalent in 34% of patients in the urban study sample compared to 12.3% in rural. Dyslipidaemia was observed in 86.0% of patients in the urban study sample compared to 66.67% in rural. Finally, physical inactivity was identified in 67.7% of patients in the urban study sample compared to 36.67% in rural. Conclusion: Blood sugar, both fasting and postprandial was significantly higher in the urban study population as compared to rural. The same variation in HbA1c level was also observed. Incidence of obesity along with dyslipidaemia was more pronounced in urban as compared to the rural population. Obesity and lipid profile showed a positive ...
    Keywords cardiovascular diseases ; glycosylated haemoglobin ; hypertension ; metabolic syndrome ; obesity ; Microbiology ; QR1-502 ; Chemistry ; QD1-999
    Subject code 910
    Language English
    Publishing date 2020-07-01T00:00:00Z
    Publisher JCDR Research and Publications Pvt. Ltd.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Tuberous Sclerosis

    Shubhransu Patro / Pankaj Kumar Khora / Bijay Kumar Sahoo / Debasis Pathi

    Journal of Clinical and Diagnostic Research, Vol 14, Iss 2, Pp OD14-OD

    A Rare Cause Section of Seizure in an Older Adult

    2020  Volume 16

    Abstract: Tuberous sclerosis is a rare autosomal dominant genetic disorder caused by mutation of TCS1 or TCS2 gene. The birth incidence is estimated to be 1 in 6000. It is a multisystem neurocutaneous disorder characterised by widespread hamartomas, cutaneous ... ...

    Abstract Tuberous sclerosis is a rare autosomal dominant genetic disorder caused by mutation of TCS1 or TCS2 gene. The birth incidence is estimated to be 1 in 6000. It is a multisystem neurocutaneous disorder characterised by widespread hamartomas, cutaneous changes and neurological manifestations. It may present as seizures in adult patients and being a rare aetiology, presents a diagnostic challenge to physicians. Here, the authors report a case of a 48-year-old male who presented with recent onset of seizures and subsequently was found to have tuberous sclerosis. He was managed with oral levetiracetam and remained asymptomatic during follow-ups, over a period of two years.
    Keywords adenoma sebaceum ; genetic disorder ; hypopigmented skin lesions ; mtor ; phakomatosis ; Medicine ; R
    Language English
    Publishing date 2020-02-01T00:00:00Z
    Publisher JCDR Research and Publications Private Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Prevalence of uropathogens and their antimicrobial resistance pattern among adult diabetic patients

    Sushant Kande / Shubhransu Patro / Ansuman Panigrahi / Pankaj Kumar Khora / Dipti Pattnaik

    Indian Journal of Public Health, Vol 65, Iss 3, Pp 280-

    2021  Volume 286

    Abstract: Background: The high prevalence of diabetes, urinary tract infection (UTI) in persons with diabetes, and antibiotic resistance throughout the world including India is a cause of concern for health-care providers. Objectives: The study aimed to assess the ...

    Abstract Background: The high prevalence of diabetes, urinary tract infection (UTI) in persons with diabetes, and antibiotic resistance throughout the world including India is a cause of concern for health-care providers. Objectives: The study aimed to assess the prevalence of uropathogens, their resistance pattern, and associated factors of UTI among adults with diabetes. Methods: A cross-sectional study was conducted during the year 2018–2019 among 504 adult diabetic patients attending a tertiary care hospital of Bhubaneswar, Eastern India. Using recommended culture methods, clean-catch midstream urine samples were examined for the presence of pathogenic bacteria and their antimicrobial susceptibility pattern. Results: The prevalence of UTI was 75.4% and the predominant isolates were Escherichia coli (25.6%), Enterococcus spp. (18.7%), and Klebsiella spp. (8.1%). Most of the bacteria isolates were sensitive to nitrofurantoin (80.8%), gentamicin (76.8%), and amikacin (72.1%) whereas resistant to cefpodoxime (77.6%), cefixime (70.8%), and cefadroxil (65.0%). The overall multidrug resistance (MDR) to two or more antimicrobial agents was observed in 87.4% bacterial isolates. The odds of developing UTIs were significantly higher in females with diabetes (adjusted odds ratio [AOR]: 2.04; 95% confidence interval CI: 1.33–3.13), those with Stage I/II hypertension (AOR: 1.77; 95% CI: 1.04–3.008), and those having glycated hemoglobin level >9% (75 mmol) (AOR: 2.15; 95% CI: 1.13–4.10) compared with their counterparts. Conclusion: The prevalence of UTI and MDR to commonly used antibiotics among diabetic patients is alarming, and thus, isolation of uropathogenic bacteria and antimicrobial susceptibility testing is crucial for the treatment of UTI in persons with diabetes.
    Keywords diabetes mellitus ; glycated hemoglobin ; hypertension ; multidrug resistance ; urinary tract infection ; Public aspects of medicine ; RA1-1270
    Subject code 571
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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