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  1. Article ; Online: Analysis of genetic diversity in indian natural populations ofdrosophila ananassae

    Pranveer Singh / Pankaj Narula / Sarita Azad

    Frontiers in Bioscience-Elite, Vol 12, Iss 2, Pp 237-

    2020  Volume 253

    Abstract: Forty five natural populations of Drosophila ananassae, collected from entire geo-climatic regions of the India were analyzed to determine the distribution of genetic diversity relative to different eco-geographic factors. Quantitative data on the ... ...

    Abstract Forty five natural populations of Drosophila ananassae, collected from entire geo-climatic regions of the India were analyzed to determine the distribution of genetic diversity relative to different eco-geographic factors. Quantitative data on the frequencies of three cosmopolitan inversions in the sampled populations were utilized to deduce Nei’s gene diversity estimates. Populations were grouped according to the time of collection (years and month); collection-regions like coastal and mainland regions, and collection-seasons. Further, data was subjected to network analysis to detect community structure in the populations and Modularity analysis to quantify the strength in community structure. Gene-diversity statistics revealed the presence of significant variability in the Indian natural populations of D.ananassae. Off all the parameters used to group the populations, geographical attributes seems to have maximum, while the time of collection and seasons have minimum influence on the genetic variability in Indian natural populations of D.ananassae. The results clearly link the association of genetic variability with environmental heterogeneity, elucidating the role of environment specific natural selection. The homogenizing effects could be due to genetic hitchhiking and canalization.
    Keywords gene diversity ; network analysis ; modularity ; inversions ; chromosome polymorphism ; Environmental sciences ; GE1-350 ; Microbiology ; QR1-502
    Subject code 580
    Language English
    Publishing date 2020-06-01T00:00:00Z
    Publisher IMR Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Analyzing seasonality of tuberculosis across Indian states and union territories

    Pankaj Narula / Praveer Sihota / Sarita Azad / Pietro Lio

    Journal of Epidemiology and Global Health, Vol 5, Iss

    2019  Volume 4

    Abstract: A significant seasonal variation in tuberculosis (TB) is observed in north India during 2006–2011, particularly in states like Himachal Pradesh, Haryana and Rajasthan. To quantify the seasonal variation, we measure average amplitude (peak to trough ... ...

    Abstract A significant seasonal variation in tuberculosis (TB) is observed in north India during 2006–2011, particularly in states like Himachal Pradesh, Haryana and Rajasthan. To quantify the seasonal variation, we measure average amplitude (peak to trough distance) across seasons in smear positive cases of TB and observe that it is maximum for Himachal Pradesh (40.01%) and minimum for Maharashtra (3.87%). In north India, smear positive cases peak in second quarter (April–June) and reach a trough in fourth quarter (October–December), however low seasonal variation is observed in southern region of the country. The significant correlations as 0.64 (p-value < 0.001), 0.54 (p-value < 0.01) and 0.42 (p-value < 0.05) are observed between minimum temperature and seasonality of TB at lag-1 in north, central and northeast India respectively. However, in south India, this correlation is not significant.
    Keywords Tuberculosis ; Seasonality ; Poisson regression ; Smear positive cases ; Temperature ; Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2019-04-01T00:00:00Z
    Publisher Springer
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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