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  1. Article: Secondary Hemophagocytic Lymphohistiocytosis: Think of the Devil Lurking!

    Pannu, Ashok K / Bhalla, Ashish

    Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine

    2022  Volume 26, Issue 5, Page(s) 545–546

    Abstract: How to cite this article: ...

    Abstract How to cite this article:
    Language English
    Publishing date 2022-06-13
    Publishing country India
    Document type Editorial
    ZDB-ID 2121263-6
    ISSN 1998-359X ; 0972-5229
    ISSN (online) 1998-359X
    ISSN 0972-5229
    DOI 10.5005/jp-journals-10071-24216
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Malaria today: advances in management and control.

    Pannu, Ashok K

    Tropical doctor

    2019  Volume 49, Issue 3, Page(s) 160–164

    Abstract: Over the past two decades, malaria-related deaths have reduced substantially, especially in African children. However, the global malaria burden still remains high. The recent emergence of resistance to artemisinin, the backbone of malaria management, ... ...

    Abstract Over the past two decades, malaria-related deaths have reduced substantially, especially in African children. However, the global malaria burden still remains high. The recent emergence of resistance to artemisinin, the backbone of malaria management, could threaten malaria control. Importantly, over the past five years, there has been an upsurge in research in the development of novel antimalarial drugs (and combinations), malaria vaccine and new vector-control strategies that can boost the malaria control programme.
    MeSH term(s) Antimalarials/pharmacology ; Antimalarials/therapeutic use ; Artemisinins/pharmacology ; Artemisinins/therapeutic use ; Drug Discovery ; Drug Resistance ; Global Health ; Humans ; Malaria/epidemiology ; Malaria/prevention & control ; Malaria Vaccines/administration & dosage ; Malaria Vaccines/pharmacology ; Mosquito Control ; Plasmodium/drug effects
    Chemical Substances Antimalarials ; Artemisinins ; Malaria Vaccines ; artemisinin (9RMU91N5K2)
    Language English
    Publishing date 2019-05-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 193169-6
    ISSN 1758-1133 ; 0049-4755
    ISSN (online) 1758-1133
    ISSN 0049-4755
    DOI 10.1177/0049475519846382
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Acute-onset Breathlessness: An Unexpected Etiology?

    Anbalagan, Lokhesh C / Muthu, Valliappan / Pannu, Ashok K / Saroch, Atul

    Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine

    2022  Volume 26, Issue 2, Page(s) 231–234

    Abstract: Acute-onset breathlessness has multifactorial causes where early spotting of etiology assists in prompt treatment of these cases. Other than usual causes, an often-neglected cause, especially in adults, is non-asphyxiating foreign body aspiration. Here, ... ...

    Abstract Acute-onset breathlessness has multifactorial causes where early spotting of etiology assists in prompt treatment of these cases. Other than usual causes, an often-neglected cause, especially in adults, is non-asphyxiating foreign body aspiration. Here, we describe a case of a 40-year-old male who had aspirated an organic foreign body under alcohol intoxication and presented with symptoms of acute-onset breathlessness and severe hypoxia. Prompt diagnosis and bronchoscopy-guided removal result in a quick recovery of symptoms in the index patient.
    How to cite this article: Anbalagan LC, Muthu V, Pannu AK, Saroch A. Acute-onset Breathlessness: An Unexpected Etiology? Indian J Crit Care Med 2022;26(2):231-234.
    Language English
    Publishing date 2022-05-30
    Publishing country India
    Document type Case Reports
    ZDB-ID 2121263-6
    ISSN 1998-359X ; 0972-5229
    ISSN (online) 1998-359X
    ISSN 0972-5229
    DOI 10.5005/jp-journals-10071-24112
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Primary pulmonary nocardiosis by

    Pannu, Sanju / Pannu, Ashok K

    Journal of family medicine and primary care

    2019  Volume 8, Issue 9, Page(s) 3035–3038

    Abstract: Infection ... ...

    Abstract Infection by
    Language English
    Publishing date 2019-09-30
    Publishing country India
    Document type Case Reports
    ZDB-ID 2735275-4
    ISSN 2278-7135 ; 2249-4863
    ISSN (online) 2278-7135
    ISSN 2249-4863
    DOI 10.4103/jfmpc.jfmpc_576_19
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Towards Eradication of Malaria: Is the WHO's RTS,S/AS01 Vaccination Effective Enough?

    Arora, Navneet / C Anbalagan, Lokhesh / Pannu, Ashok K

    Risk management and healthcare policy

    2021  Volume 14, Page(s) 1033–1039

    Abstract: Background: Recent advances in mosquito eradication and antimalarial treatments have reduced the malaria burden only modestly. An effective malaria vaccine remains a high priority, but its development has several challenges. Among many potential ... ...

    Abstract Background: Recent advances in mosquito eradication and antimalarial treatments have reduced the malaria burden only modestly. An effective malaria vaccine remains a high priority, but its development has several challenges. Among many potential candidates, the RTS,S/AS01 vaccine (Mosquirix
    Objective and method: This review aims to understand the advances in the RTS,S/AS01 vaccine, and future comments regarding the vaccine's effectiveness in malaria eradication. Literature review for the past five decades was performed searching PubMed, EMBASE Ovid, and Cochrane Library, with using the following search items: ("malaria" OR "WHO's malaria" OR "Plasmodium falciparum" OR "RTS,S" OR "RTS,S/AS01" OR "RTS,S/AS02" OR "pre-erythrocytic malaria" OR "circumsporozoite" OR "Mosquirix") AND ("vaccine" OR "vaccination").
    Results: RTS,S/AS01, a recombinant pre-erythrocytic vaccine containing
    Conclusion: The RTS,S/AS01 vaccine prevents malaria; however, it should be considered another addition to the malaria-control program and not as an eradication tool because of its relatively low to modest efficacy.
    Language English
    Publishing date 2021-03-12
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2495128-6
    ISSN 1179-1594
    ISSN 1179-1594
    DOI 10.2147/RMHP.S219294
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Management of Acute Aluminum Phosphide Poisoning: Has Anything Changed?

    Anbalagan, Lokhesh C / Arora, Navneet / Pannu, Ashok K

    Drug metabolism letters

    2021  Volume 14, Issue 2, Page(s) 106–116

    Abstract: Due to its easy availability, rapid and severe toxicity, and no specific antidote, aluminum phosphide has emerged as a lethal toxin, commonly used for suicidal intent in agricultural communities. Despite various advances in medicine, this compound's ... ...

    Abstract Due to its easy availability, rapid and severe toxicity, and no specific antidote, aluminum phosphide has emerged as a lethal toxin, commonly used for suicidal intent in agricultural communities. Despite various advances in medicine, this compound's toxicity is poorly understood, and it still has a very high case fatality rate with no definitive treatment options available. This review aims to understand the mechanism of toxicity, clinical toxidrome of acute aluminum phosphide poisoning, and the available therapeutic options, including recent advances. A literature review was performed searching PubMed, EMBASE Ovid, and Cochrane Library, using the following search items: ("aluminum phosphide poisoning" OR "aluminum phosphide poisoning toxicity" OR "aluminum phosphide ingestion") AND ("management" OR "therapy" OR "treatment"). Selected articles were discussed amongst all the authors to shape this review. High case fatality rate and lack of any specific antidote are persisting challenges. Therapeutic measures need to be implemented from all fronts - reducing easy access to the poison, developing less toxic alternatives for use as a pesticide, and more studies directed at developing an effective reversal agent for phosphine. The advent of promising agents like glucose-insulin-potassium infusion and lipid emulsion is a new ray of hope in the complete recovery in this fatal poisoning. The need of the hour is to find an agent that rapidly and effectively reverses aluminum phosphide's toxic effects. Large multicenter controlled trials are required to establish the role of glucose-insulin-potassium and lipid emulsion.
    MeSH term(s) Aluminum Compounds ; Antidotes/therapeutic use ; Glucose ; Humans ; Multicenter Studies as Topic ; Pesticides ; Phosphines
    Chemical Substances Aluminum Compounds ; Antidotes ; Pesticides ; Phosphines ; aluminum phosphide (E23DR6L59S) ; Glucose (IY9XDZ35W2)
    Language English
    Publishing date 2021-10-21
    Publishing country United Arab Emirates
    Document type Journal Article ; Review
    ISSN 1874-0758
    ISSN (online) 1874-0758
    DOI 10.2174/1872312814666210813115625
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Disseminated Varicella Infection.

    Pannu, Ashok K / Manikandan, Gopal

    The New England journal of medicine

    2019  Volume 381, Issue 11, Page(s) e21

    MeSH term(s) Adult ; Anemia, Aplastic/complications ; Chickenpox/complications ; Chickenpox/diagnosis ; Fatal Outcome ; Humans ; Lung/diagnostic imaging ; Lung/pathology ; Male ; Radiography, Thoracic ; Skin/pathology
    Language English
    Publishing date 2019-09-11
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMicm1814626
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Acceptance of coronavirus disease 2019 vaccine among health-care personnel in India: a cross-sectional survey during the initial phase of vaccination.

    Singhania, Nikhil / Kathiravan, Sanjana / Pannu, Ashok K

    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

    2021  Volume 27, Issue 7, Page(s) 1064–1066

    MeSH term(s) Adolescent ; Adult ; Aged ; COVID-19/prevention & control ; COVID-19 Vaccines/immunology ; Cross-Sectional Studies ; Data Collection ; Female ; Health Knowledge, Attitudes, Practice ; Health Personnel ; Humans ; India ; Male ; Middle Aged ; Patient Acceptance of Health Care ; SARS-CoV-2 ; Surveys and Questionnaires ; Vaccination ; Young Adult
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2021-03-31
    Publishing country England
    Document type Letter
    ZDB-ID 1328418-6
    ISSN 1469-0691 ; 1470-9465 ; 1198-743X
    ISSN (online) 1469-0691
    ISSN 1470-9465 ; 1198-743X
    DOI 10.1016/j.cmi.2021.03.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Snake Envenomation.

    Pannu, Ashok K / Reddy, Sai P / Sharma, Navneet

    The New England journal of medicine

    2021  Volume 386, Issue 11, Page(s) 1099–1100

    MeSH term(s) Animals ; Humans ; Snake Bites/complications ; Snake Bites/therapy ; Snakes
    Language English
    Publishing date 2021-10-19
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc2201552
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: A Simple Tool Predicts Mortality in Aluminum Phosphide Self-poisoning.

    Pannu, Ashok K / Bhalla, Ashish

    Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine

    2019  Volume 24, Issue 9, Page(s) 755–756

    Abstract: Incorporating the toxidrome-specific prognostic systems into the daily emergency department practice might become a standard of care in low- and middle-income countries. The PGI score is appealing because it is quick and easy, it accurately identifies ... ...

    Abstract Incorporating the toxidrome-specific prognostic systems into the daily emergency department practice might become a standard of care in low- and middle-income countries. The PGI score is appealing because it is quick and easy, it accurately identifies high-risk patients at in-hospital mortality, and it shows promise in predicting those at low risk. Although further validation of the PGI score is required in more extensive studies, it can help direct appropriate resources to those most likely to benefit and stratify patients for testing novel clinical interventions.
    Language English
    Publishing date 2019-07-05
    Publishing country India
    Document type Editorial
    ZDB-ID 2121263-6
    ISSN 1998-359X ; 0972-5229
    ISSN (online) 1998-359X
    ISSN 0972-5229
    DOI 10.5005/jp-journals-10071-23583
    Database MEDical Literature Analysis and Retrieval System OnLINE

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