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Book ; Online: Einführung von medizintechnischen Innovationen im Krankenhaus

Panteli, Dimitra / Henschke, Cornelia / Eckhardt, Helene / Busse, Reinhard

Eine systematische Analyse von 27 neuen Untersuchungs- und Behandlungsmethoden zwischen 2005 und 2017: Diffusion, Evidenz und Forschungsaktivitäten

(Working papers in health services research)

2023

Series title	Working papers in health services research
Keywords	Public health & preventive medicine ; health technologies ; benefit assessment ; evidenced based medicine ; inpatient care ; regulation
Language	German
Size	1 electronic resource (306 pages)
Publisher	Universitätsverlag der Technischen Universität Berlin
Publishing place	Berlin
Document type	Book ; Online
Note	German
HBZ-ID	HT030374979
ISBN	9783798332614 ; 3798332614
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Book ; Online: Internationale Datengrundlagen für die Versorgungsforschung

Panteli, Dimitra / Röttger, Julia / Nimptsch, Ulrike / Busse, Reinhard

Impulse für Deutschland

(Working papers in health policy and management)

2022

Series title	Working papers in health policy and management
Keywords	Medicine ; data linkage; health services research; cross-country learning; data policy; health systems
Language	0\|d
Size	1 electronic resource (161 pages)
Publisher	Universitätsverlag der Technischen Universität Berlin
Publishing place	Berlin
Document type	Book ; Online
Note	German ; Open Access
HBZ-ID	HT021618299
ISBN	9783798332171 ; 3798332177
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article ; Online: How did the COVID-19 pandemic affect inpatient care for children in Germany? An exploratory analysis based on national hospital discharge data.

Panteli, Dimitra / Mauer, Nicole / Tille, Florian / Nimptsch, Ulrike

BMC health services research

2023 Volume 23, Issue 1, Page(s) 938

Abstract: Background: The delivery of health services around the world faced considerable disruptions during the COVID-19 pandemic. While this has been discussed for a number of conditions in the adult population, related patterns have been studied less for ... ...

Abstract	Background: The delivery of health services around the world faced considerable disruptions during the COVID-19 pandemic. While this has been discussed for a number of conditions in the adult population, related patterns have been studied less for children. In light of the detrimental effects of the pandemic, particularly for children and young people under the age of 18, it is pivotal to explore this issue further. Methods: Based on complete national hospital discharge data available via the German National Institute for the Reimbursement of Hospitals (InEK) data browser, we compare the top 30 diagnoses for which children were hospitalised in 2019, 2020, 2021 and 2022. We analyse the development of monthly admissions between January 2019 and December 2022 for three tracers of variable time-sensitivity: acute lymphoblastic leukaemia (ALL), appendicitis/appendectomy and tonsillectomy/adenoidectomy. Results: Compared to 2019, total admissions were approximately 20% lower in 2020 and 2021, and 13% lower in 2022. The composition of the most frequent principal diagnoses remained similar across years, although changes in rank were observed. Decreases were observed in 2020 for respiratory and gastrointestinal infections, with cases increasing again in 2021. The number of ALL admissions showed an upward trend and a periodicity prima vista unrelated to pandemic factors. Appendicitis admissions decreased by about 9% in 2020 and a further 8% in 2021 and 4% in 2022, while tonsillectomies/adenoidectomies decreased by more than 40% in 2020 and a further 32% in 2021 before increasing in 2022; for these tracers, monthly changes are in line with pandemic waves. Conclusions: Hospital care for critical and urgent conditions among patients under the age of 18 was largely upheld in Germany during the COVID-19 pandemic, potentially at the expense of elective treatments. There is an alignment between observed variations in hospitalisations and pandemic mitigation measures, possibly also reflecting changes in demand. This study highlights the need for comprehensive, intersectoral data that would be necessary to better understand changing demand, unmet need/foregone care and shifts from inpatient to outpatient care, as well as their link to patient outcomes and health care efficiency.
MeSH term(s)	Adult ; Humans ; Child ; Adolescent ; COVID-19/epidemiology ; Pandemics ; Appendicitis/epidemiology ; Appendicitis/surgery ; Inpatients ; Patient Discharge ; Hospitalization ; Hospitals ; Germany/epidemiology
Language	English
Publishing date	2023-08-31
Publishing country	England
Document type	Journal Article
ZDB-ID	2050434-2
ISSN	1472-6963 ; 1472-6963
ISSN (online)	1472-6963
ISSN	1472-6963
DOI	10.1186/s12913-023-09929-z
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Regulating the health workforce in Europe: implications of the COVID-19 pandemic.

Panteli, Dimitra / Maier, Claudia B

Human resources for health

2021 Volume 19, Issue 1, Page(s) 80

Abstract: In the European free movement zone, various mechanisms aim to harmonize how the competence of physicians and nurses is developed and maintained to facilitate the cross-country movement of professionals. This commentary addresses these mechanisms and ... ...

Abstract	In the European free movement zone, various mechanisms aim to harmonize how the competence of physicians and nurses is developed and maintained to facilitate the cross-country movement of professionals. This commentary addresses these mechanisms and discusses their implications during the COVID-19 pandemic, drawing lessons for future policy. It argues that EU-wide regulatory mechanisms should be reviewed to ensure that they provide an adequate foundation for determining competence and enabling health workforce flexibility during health system shocks. Currently, EU regulation focuses on the automatic recognition of the primary education of physicians and nurses. New, flexible mechanisms should be developed for specializations, such as intensive or emergency care. Documenting new skills, such as the ones acquired during rapid training in the pandemic, in a manner that is comparable across countries should be explored, both for usual practice and in light of outbreak preparedness. Initiatives to strengthen continuing education and professional development should be supported further. Funding under the EU4Health programme should be dedicated to this endeavour, along with revisiting the scope of necessary skills following the experience of COVID-19. Mechanisms for cross-country sharing of information on violations of good practice standards should be maintained and strengthened to enable agile reactions when the need for professional mobility becomes urgent.
MeSH term(s)	COVID-19/epidemiology ; Education, Continuing/standards ; Europe/epidemiology ; Guideline Adherence/standards ; Health Workforce/standards ; Humans ; Information Dissemination ; International Cooperation ; Pandemics ; Professional Competence/standards ; SARS-CoV-2
Language	English
Publishing date	2021-07-10
Publishing country	England
Document type	Letter
ISSN	1478-4491
ISSN (online)	1478-4491
DOI	10.1186/s12960-021-00624-w
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Digital Health Applications (DiHA): Approaches to develop a reimbursement process for the statutory health insurance in Austria.

Goetz, Gregor / Jeindl, Reinhard / Panteli, Dimitra / Busse, Reinhard / Wild, Claudia

Health policy and technology

2023 Volume 12, Issue 3, Page(s) None

Abstract: Purpose: To elaborate a concept for implementing digital health applications (DiHA), including prioritisation criteria (PC) for the Austrian context and an overview of available prioritised DiHAs.: Methods: Based on European DiHA-listings and input ... ...

Abstract	Purpose: To elaborate a concept for implementing digital health applications (DiHA), including prioritisation criteria (PC) for the Austrian context and an overview of available prioritised DiHAs. Methods: Based on European DiHA-listings and input by Austrian experts, a categorised meta-directory of DiHAs was created. PC were developed to reflect, inter alia, the provisions of the Austrian General Insurance Act, and were applied to the meta-directory to identify DiHAs potentially relevant for the Austrian statutory health insurance. An iterative process with expert involvement was used to tailor an existing reimbursement framework to the Austrian setting. Results: The meta-directory comprised 132 DiHAs. Developed PC focused on plausibility (German language) and legal aspects (treatment/monitoring of chronic conditions), while other criteria (e.g. interoperability standards) were considered optional. After applying the PC, 38 DiHAs were potentially relevant in the Austrian setting. Of these, only seven supported current health record integration. Most of the prioritised DiHAs reported on CE marking (29/38) and data protection (35/38), while reporting on risk class (10/38) and technical algorithms (0/38) was sparse. For DiHA reimbursement, a four-step process is proposed: identification (ideally based on needs assessment); filtering based on PC; review of technical, regulatory and evidentiary requirements; and health technology assessment. Conclusion: The proposed concept can offer guidance for policy makers (e.g., on prioritising available DiHAs) and may further foster scientific debate with regard to DiHA implementation. Further discussion on how to fully incorporate regulatory, technical, and evidentiary criteria is needed. Attention should be given to national implementation requirements, re-assessment criteria, and appropriate remuneration schemes.
Language	English
Publishing date	2023-09-04
Publishing country	Netherlands
Document type	Journal Article
ISSN	2211-8837
ISSN	2211-8837
DOI	10.1016/j.hlpt.2023.100780
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Reimbursement decisions for medical services in Austria: an analysis of influencing factors for the hospital individual services catalogue between 2008 and 2020.

Goetz, Gregor / Panteli, Dimitra / Busse, Reinhard / Wild, Claudia

BMC health services research

2022 Volume 22, Issue 1, Page(s) 205

Abstract: Objectives: To (1) describe the (evidence-based) reimbursement process of hospital individual services, (2) evaluate the accordance between evidence-based recommendations and reimbursement decision of individual services and (3) elaborate potential ... ...

Abstract	Objectives: To (1) describe the (evidence-based) reimbursement process of hospital individual services, (2) evaluate the accordance between evidence-based recommendations and reimbursement decision of individual services and (3) elaborate potential aspects that play a role in the decision-making process in Austria. Method: The reimbursement process is described based on selected relevant sources such as official documents. Evidence-based recommendations and subsequent reimbursement decisions for the annual maintenance of the hospital individual service catalogue in Austria between 2008 and 2020 were analysed using a mixed methods approach, encompassing descriptive statistics and a focus group with Austrian decision makers. Results: 118 evidence-based recommendations were analysed. There were 93 (78.8%) negative and 25 (21.2%) positive evidence-based recommendations. In total, 107 out of 118 evidence-based recommendations (90.1%) did not lead to a deviating reimbursement decision. We identified six aspects that may have played a role in the decision-making process for the annual maintenance of the hospital individual service catalogue, with clinical evidence being the most notable. Further aspects included quality assurance/organisational aspects (i.e., structural quality assurance), costs (if comparable to already existing medical services, not: cost-effectiveness), procedural aspects (e.g., if certain criteria for adoption have not been met formally through the proposals), "other countries" (i.e., taking into account how other countries decided) and situational aspects (such as the COVID-19 pandemic). Conclusions: There is good accordance between evidence-based recommendations and reimbursement decisions regarding hospital individual services in Austria. Beyond clinical evidence, organisational aspects seem to be considered often with regard to quality assurance but costs do not appear to play a major role. The Austrian system has mechanisms in place that can restrict widespread adoption of novel hospital individual services with uncertain clinical benefits. Future studies could investigate how well these mechanisms work and how they compare to other health systems in Europe.
MeSH term(s)	Austria ; COVID-19 ; Cost-Benefit Analysis ; Hospitals ; Humans ; Pandemics ; SARS-CoV-2
Language	English
Publishing date	2022-02-15
Publishing country	England
Document type	Journal Article
ZDB-ID	2050434-2
ISSN	1472-6963 ; 1472-6963
ISSN (online)	1472-6963
ISSN	1472-6963
DOI	10.1186/s12913-022-07531-3
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book ; Online: How can the EU support sustainable innovation and access to effective antibiotics? Policy options for existing and new medicines

Anderson, Michael / Panteli, Dimitra / Mossialos, Elias

2023

Abstract: 71 p. ... Antimicrobial and particularly antibiotic resistance is one of the biggest public health challenges the world faces. Over 1 million years of life are lost each year in the European Union (EU)/European Economic Area (EEA) alone due to antibiotic ... ...

Abstract	71 p. Antimicrobial and particularly antibiotic resistance is one of the biggest public health challenges the world faces. Over 1 million years of life are lost each year in the European Union (EU)/European Economic Area (EEA) alone due to antibiotic resistance, and it costs healthcare systems about €1.1 billion annually. These health and economic impacts are expected to worsen. Urgent steps are needed and this policy brief focuses on one area where the EU and its Member States can take effective action, fostering sustainable innovation and improving access to effective antibiotics:1. Scientific, economic, structural and regulatory ‘barriers’ continue to limit the development of novel antibiotics with innovative characteristics despite intensified international efforts.2. Reinvigorating the antibiotic pipeline requires a holistic package of incentives.3. Ensuring timely access to new and existing antibiotics is critical.4. Improving access to effective antibiotics requires both short- and longer-term measures.5. The EU has a major role to play both in combatting antimicrobial resistance (AMR) and in contributing to global solutions.
Keywords	Health Policy ; Drug Resistance ; Bacterial ; Microbial ; Biomedical Research ; Anti-Bacterial Agents
Language	English
Publishing date	2023-06-21
Publisher	World Health Organization. Regional Office for Europe.
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Who should be vaccinated first? Comparing vaccine prioritization strategies in Israel and European countries using the Covid-19 Health System Response Monitor.

Cylus, Jonathan / Panteli, Dimitra / van Ginneken, Ewout

Israel journal of health policy research

2021 Volume 10, Issue 1, Page(s) 16

Abstract: The rapid rollout of Israel's vaccination program has led to considerable international interest. In this brief commentary we consider how the criteria for vaccination priority groups differ between Israel and selected European countries. We argue that ... ...

Abstract	The rapid rollout of Israel's vaccination program has led to considerable international interest. In this brief commentary we consider how the criteria for vaccination priority groups differ between Israel and selected European countries. We argue that following the Israeli approach of using broad criteria for prioritization- i.e. having fewer groups and a lower age threshold- could have several beneficial effects, including more manageable logistics and fewer roll out delays, as well as potentially reducing pressure on hospitals. With an increasing supply of vaccines becoming available rapidly in much of Europe, countries could consider following the approach of Israel and adopting broader priority criteria going forward.
MeSH term(s)	Adult ; Age Factors ; Aged ; Aged, 80 and over ; COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19 Vaccines/administration & dosage ; COVID-19 Vaccines/supply & distribution ; Eligibility Determination/methods ; Europe/epidemiology ; Health Policy ; Health Priorities ; Humans ; Immunization Programs/organization & administration ; Israel/epidemiology ; Middle Aged
Chemical Substances	COVID-19 Vaccines
Language	English
Publishing date	2021-02-19
Publishing country	England
Document type	Journal Article
ZDB-ID	2657655-7
ISSN	2045-4015 ; 2045-4015
ISSN (online)	2045-4015
ISSN	2045-4015
DOI	10.1186/s13584-021-00453-1
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Bericht zum Workshop „Environmental Impact: eine neue Dimension in der Bewertung medizinischer Technologien? Ein Workshop mit Fokus auf Medizinprodukte“, EbM-Kongress in Potsdam 23.3.2023.

Perleth, Matthias / Spranger, Anne / Wabnitz, Katharina / Panteli, Dimitra / Kolominsky-Rabas, Peter

Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen

2023 Volume 181, Page(s) 76–79

Title translation	Report on the workshop "Environmental Impact: A new dimension in health technology assessment? A workshop focussing on medical devices", EbM Congress in Potsdam on March 23, 2023.
MeSH term(s)	Humans ; Technology Assessment, Biomedical ; Germany ; Clinical Competence ; Evidence-Based Medicine
Language	German
Publishing date	2023-08-16
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2412512-X
ISSN	2212-0289 ; 1865-9217
ISSN (online)	2212-0289
ISSN	1865-9217
DOI	10.1016/j.zefq.2023.06.008
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Challenges and opportunities for incentivising antibiotic research and development in Europe.

Anderson, Michael / Panteli, Dimitra / van Kessel, Robin / Ljungqvist, Gunnar / Colombo, Francesca / Mossialos, Elias

The Lancet regional health. Europe

2023 Volume 33, Page(s) 100705

Abstract: Antimicrobial, and particularly antibiotic resistance are one of the world's biggest challenges today, and urgent action is needed to reinvigorate the antibiotic development pipeline. To inform policy discussions during and after the 2023 Swedish ... ...

Abstract	Antimicrobial, and particularly antibiotic resistance are one of the world's biggest challenges today, and urgent action is needed to reinvigorate the antibiotic development pipeline. To inform policy discussions during and after the 2023 Swedish Presidency of the Council of the European Union, we critically appraise incentive options recently proposed by the European Commission, and member states, and consider what has been achieved over the last two decades in relation to antibiotic research and development. While several new antibiotics have achieved regulatory approval in recent years, almost none have innovative characteristics such as new chemical classes or novel mechanisms of action. We consider four incentive options to incentivise research and development of new antibiotics, including subscription payments, market entry rewards, transferable exclusivity extensions, and milestone payments. While each option has advantages and drawbacks, a combination of incentives may be required and continued investment is needed by the EU in push incentives, such as direct funding and grants, to incentivise drug discovery and preclinical stages of development. The EU must also coordinate with international initiatives and support access to new and pre-existing antibiotics in LMICs through platforms such as the WHO, and G7 and G20 group of countries.
Language	English
Publishing date	2023-07-26
Publishing country	England
Document type	Journal Article ; Review
ISSN	2666-7762
ISSN (online)	2666-7762
DOI	10.1016/j.lanepe.2023.100705
Database	MEDical Literature Analysis and Retrieval System OnLINE

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