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  1. Article ; Online: Correction: Plasmids manipulate bacterial behaviour through translational regulatory crosstalk.

    Thompson, Catriona M A / Hall, James P J / Chandra, Govind / Martins, Carlo / Saalbach, Gerhard / Panturat, Supakan / Bird, Susannah M / Ford, Samuel / Little, Richard H / Piazza, Ainelen / Harrison, Ellie / Jackson, Robert W / Brockhurst, Michael A / Malone, Jacob G

    PLoS biology

    2024  Volume 22, Issue 2, Page(s) e3002531

    Abstract: This corrects the article DOI: 10.1371/journal.pbio.3001988.]. ...

    Abstract [This corrects the article DOI: 10.1371/journal.pbio.3001988.].
    Language English
    Publishing date 2024-02-15
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 2126776-5
    ISSN 1545-7885 ; 1544-9173
    ISSN (online) 1545-7885
    ISSN 1544-9173
    DOI 10.1371/journal.pbio.3002531
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6193: Show issues Location:
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  2. Article ; Online: Frontiers in antibiotic alternatives for

    Phanchana, Matthew / Harnvoravongchai, Phurt / Wongkuna, Supapit / Phetruen, Tanaporn / Phothichaisri, Wichuda / Panturat, Supakan / Pipatthana, Methinee / Charoensutthivarakul, Sitthivut / Chankhamhaengdecha, Surang / Janvilisri, Tavan

    World journal of gastroenterology

    2021  Volume 27, Issue 42, Page(s) 7210–7232

    Abstract: Clostridioides ... ...

    Abstract Clostridioides difficile
    MeSH term(s) Anti-Bacterial Agents/adverse effects ; Clostridioides difficile ; Clostridium Infections/diagnosis ; Clostridium Infections/drug therapy ; Clostridium Infections/epidemiology ; Fecal Microbiota Transplantation ; Humans ; Vaccine Development
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2021-12-03
    Publishing country United States
    Document type Editorial
    ZDB-ID 2185929-2
    ISSN 2219-2840 ; 1007-9327
    ISSN (online) 2219-2840
    ISSN 1007-9327
    DOI 10.3748/wjg.v27.i42.7210
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6039: Show issues Location:
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  3. Article ; Online: Plasmids manipulate bacterial behaviour through translational regulatory crosstalk.

    Thompson, Catriona M A / Hall, James P J / Chandra, Govind / Martins, Carlo / Saalbach, Gerhard / Panturat, Supakan / Bird, Susannah M / Ford, Samuel / Little, Richard H / Piazza, Ainelen / Harrison, Ellie / Jackson, Robert W / Brockhurst, Michael A / Malone, Jacob G

    PLoS biology

    2023  Volume 21, Issue 2, Page(s) e3001988

    Abstract: Beyond their role in horizontal gene transfer, conjugative plasmids commonly encode homologues of bacterial regulators. Known plasmid regulator homologues have highly targeted effects upon the transcription of specific bacterial traits. Here, we ... ...

    Abstract Beyond their role in horizontal gene transfer, conjugative plasmids commonly encode homologues of bacterial regulators. Known plasmid regulator homologues have highly targeted effects upon the transcription of specific bacterial traits. Here, we characterise a plasmid translational regulator, RsmQ, capable of taking global regulatory control in Pseudomonas fluorescens and causing a behavioural switch from motile to sessile lifestyle. RsmQ acts as a global regulator, controlling the host proteome through direct interaction with host mRNAs and interference with the host's translational regulatory network. This mRNA interference leads to large-scale proteomic changes in metabolic genes, key regulators, and genes involved in chemotaxis, thus controlling bacterial metabolism and motility. Moreover, comparative analyses found RsmQ to be encoded on a large number of divergent plasmids isolated from multiple bacterial host taxa, suggesting the widespread importance of RsmQ for manipulating bacterial behaviour across clinical, environmental, and agricultural niches. RsmQ is a widespread plasmid global translational regulator primarily evolved for host chromosomal control to manipulate bacterial behaviour and lifestyle.
    MeSH term(s) Proteomics ; Plasmids/genetics ; Bacteria/genetics ; Conjugation, Genetic/genetics ; Gene Transfer, Horizontal ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism
    Chemical Substances Bacterial Proteins
    Language English
    Publishing date 2023-02-14
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2126776-5
    ISSN 1545-7885 ; 1544-9173
    ISSN (online) 1545-7885
    ISSN 1544-9173
    DOI 10.1371/journal.pbio.3001988
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6193: Show issues Location:
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