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  1. Article ; Online: Effect of written outcome information on attitude of perinatal healthcare professionals at the limit of viability: a randomized study.

    Papadimitriou, V / Tosello, B / Pfister, R

    BMC medical ethics

    2019  Volume 20, Issue 1, Page(s) 74

    Abstract: Background: Differences in perception and potential disagreements between parents and professionals regarding the attitude for resuscitation at the limit of viability are common. This study evaluated in healthcare professionals whether the decision to ... ...

    Abstract Background: Differences in perception and potential disagreements between parents and professionals regarding the attitude for resuscitation at the limit of viability are common. This study evaluated in healthcare professionals whether the decision to resuscitate at the limit of viability (intensive care versus comfort care) are influenced by the way information on incurred risks is given or received.
    Methods: This is a prospective randomized controlled study. This study evaluated the attitude of healthcare professionals by testing the effect of information given through graphic fact sheets formulated either optimistically or pessimistically. The written educational fact sheet included three graphical presentations of survival and complication/morbidity by gestational age. The questionnaire was submitted over a period of 4 months to 5 and 6-year medical students from the Geneva University as well as physicians and nurses of the neonatal unit at the University Hospitals of Geneva. Our sample included 102 healthcare professionals.
    Results: Forty-nine responders (48%) were students (response rate of 33.1%), 32 (31%) paediatricians (response rate of 91.4%) and 21 (20%) nurses in NICU (response rate of 50%). The received risk tended to be more severe in both groups compared to the graphically presented facts and current guidelines, although optimistic representation favoured the perception of "survival without disability" at 23 to 25 weeks. Therapeutic attitudes did not differ between groups, but healthcare professionals with children were more restrained and students more aggressive at very low gestational ages.
    Conclusion: Written information on mortality and morbidity given to healthcare professionals in graphic form encourages them to overestimate the risk. However, perception in healthcare staff may not be directly transferable to parental perception during counselling as the later are usually naïve to the data received. This parental information are always communicated in ways that subtly shape the decisions that follow.
    MeSH term(s) Adult ; Attitude of Health Personnel ; Decision Making ; Female ; Gestational Age ; Humans ; Infant, Newborn ; Infant, Premature ; Intensive Care, Neonatal ; Male ; Middle Aged ; Nurses/psychology ; Optimism ; Patient Education as Topic/methods ; Pediatricians/psychology ; Perinatal Care/organization & administration ; Perinatal Care/standards ; Pessimism ; Prospective Studies ; Resuscitation/psychology ; Students, Medical/psychology
    Language English
    Publishing date 2019-10-22
    Publishing country England
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 2041552-7
    ISSN 1472-6939 ; 1472-6939
    ISSN (online) 1472-6939
    ISSN 1472-6939
    DOI 10.1186/s12910-019-0413-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Controlling the Biochemistry On-the-fly and Visualizing Reaction Dynamics during In-situ Liquid Phase TEM: A Strong Tool for Biopharmaceutical Development.

    Radhoe, Hans / Pechnikova, Evgeniya / Papadimitriou, Vasilis / Rozene, Alejandro / Sun, Hongyu / Pérez-Garza, H Hugo

    Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada

    2023  Volume 29, Issue Supplement_1, Page(s) 1120–1122

    Language English
    Publishing date 2023-08-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 1385710-1
    ISSN 1435-8115 ; 1431-9276
    ISSN (online) 1435-8115
    ISSN 1431-9276
    DOI 10.1093/micmic/ozad067.574
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: What Factors Determine the Patients’ Choice in Finding Their Office Urologist?

    Zachariou A / Dimitriadis F / Papadimitriou V / Tsafrakidis P / Haensel SM / Mamoulakis C / Haas H

    Patient Preference and Adherence, Vol Volume 15, Pp 2837-

    2021  Volume 2843

    Abstract: Athanasios Zachariou,1,2 Fotios Dimitriadis,3 Vaios Papadimitriou,4 Petros Tsafrakidis,5 Stefan M Haensel,6 Charalampos Mamoulakis,7 Helmut Haas8 1Department of Urology, University of Ioannina, Ioannina, Greece; 2Department of Urology, Physical Medicine ... ...

    Abstract Athanasios Zachariou,1,2 Fotios Dimitriadis,3 Vaios Papadimitriou,4 Petros Tsafrakidis,5 Stefan M Haensel,6 Charalampos Mamoulakis,7 Helmut Haas8 1Department of Urology, University of Ioannina, Ioannina, Greece; 2Department of Urology, Physical Medicine and Rehabilitation Centre Eu Prattein, Volos, Greece; 3Department of Urology, Aristotle University of Thessaloniki, Thessaloniki, Greece; 4Department of Urology, Private Practice, Lamia, Greece; 5Department of Urology, Mediterranean Hospital of Cyprus, Limassol, Cyprus; 6Department of Urology, Franciscus Hospital, Rotterdam, The Netherlands; 7Department of Urology, Medical School, University of Crete, Heraklion, Greece; 8EAU Section of Outpatient and Office Urology, Heppenheim, GermanyCorrespondence: Athanasios Zachariou Tel +302421026937Fax +302421026932Email zahariou@otenet.grPurpose: The present study aimed to investigate how patients identify a quality urologist in primary health care and how they determine and evaluate their provider’s qualities before their first examination.Patients and Methods: A specific questionnaire (The ESUO Questionnaire) was prepared to describe the domains that influence the patient’s evaluation and summarize the urologist related characteristics and behaviours that the patients estimate are more important. A total of 335 patients, over 18 years of age, presented in primary healthcare urology practice, completed the survey. The participants were divided into three age groups; 18– 39 years of age (111 patients), 40– 59 years of age (111 patients) and 113 patients 60 years of age and older.Results: The majority of patients (68.4%) selected that the urologist must be efficient and well trained. This attitude was primarily expressed in patients ≥ 60 years of age. Individuals under 60 years old stated that they expect a detailed examination and that the patient should be the urologist’s priority. The majority of the patients evaluates friends or family’s proposals concerning the urologist’s quality primarily and believes that there is ...
    Keywords urologist ; primary health care ; esuo questionnaire ; health care quality ; Medicine (General) ; R5-920
    Subject code 027
    Language English
    Publishing date 2021-12-01T00:00:00Z
    Publisher Dove Medical Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: Development and Study of Nanoemulsions and Nanoemulsion-Based Hydrogels for the Encapsulation of Lipophilic Compounds.

    Demisli, Sotiria / Mitsou, Evgenia / Pletsa, Vasiliki / Xenakis, Aristotelis / Papadimitriou, Vassiliki

    Nanomaterials (Basel, Switzerland)

    2020  Volume 10, Issue 12

    Abstract: Biocompatible nanoemulsions and nanoemulsion-based hydrogels were formulated for the encapsulation and delivery of vitamin ... ...

    Abstract Biocompatible nanoemulsions and nanoemulsion-based hydrogels were formulated for the encapsulation and delivery of vitamin D
    Language English
    Publishing date 2020-12-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano10122464
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Physicochemical Characteristics of Four Limonene-Based Nanoemulsions and Their Larvicidal Properties against Two Mosquito Species,

    Theochari, Ioanna / Giatropoulos, Athanasios / Papadimitriou, Vassiliki / Karras, Vasileios / Balatsos, Georgios / Papachristos, Dimitrios / Michaelakis, Antonios

    Insects

    2020  Volume 11, Issue 11

    Abstract: Negative impacts on the environment from the continuous use of synthetic insecticides against mosquitoes has driven research towards more ecofriendly products. Phytochemicals, classified as low-risk substances, have been recognized as potential ... ...

    Abstract Negative impacts on the environment from the continuous use of synthetic insecticides against mosquitoes has driven research towards more ecofriendly products. Phytochemicals, classified as low-risk substances, have been recognized as potential larvicides of mosquitoes; however, problems related to water solubility and stability are limiting factors for their use in mosquito control programs in the field. In this context, many researchers have focused on formulating essential oils in nanoemulsions, exploiting innovative nanotechnology. In the current study, we prepared 4 (R)-(+)-limonene oil-in-water nanoemulsions using low and high energy methods, and we evaluated their physicochemical characteristics (e.g., viscosity, stability, mean droplet diameter, polydispersity index) and their bioactivity against larvae of two mosquito species of great medical importance, namely,
    Language English
    Publishing date 2020-10-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662247-6
    ISSN 2075-4450
    ISSN 2075-4450
    DOI 10.3390/insects11110740
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Taxonomic diversity of microbial communities in sub-seafloor hydrothermal sediments of the active Santorini-Kolumbo volcanic field.

    Polymenakou, Paraskevi N / Nomikou, Paraskevi / Hannington, Mark / Petersen, Sven / Kilias, Stephanos P / Anastasiou, Thekla I / Papadimitriou, Vasiliki / Zaka, Eleutheria / Kristoffersen, Jon Bent / Lampridou, Danai / Wind, Sandra / Heinath, Verena / Lange, Sabine / Magoulas, Antonios

    Frontiers in microbiology

    2023  Volume 14, Page(s) 1188544

    Abstract: Introduction: Active hydrothermal vents of volcanic origin provide a remarkable manifestation of life on Earth under extreme conditions, which may have consequences for our understanding of habitability on other terrestrial bodies as well.: Methods: ... ...

    Abstract Introduction: Active hydrothermal vents of volcanic origin provide a remarkable manifestation of life on Earth under extreme conditions, which may have consequences for our understanding of habitability on other terrestrial bodies as well.
    Methods: Here, we performed for the first time Illumina sequencing of bacterial and archaeal communities on sub-seafloor samples collected from the Santorini-Kolumbo volcanic field. A total of 19 (3-m long) gravity corers were collected and processed for microbial community analysis.
    Results: From a total of 6,46,671 produced V4 sequences for all samples, a total of 10,496 different Operational Taxonomic Units (OTUs) were identified that were assigned to 40 bacterial and 9 archaeal phyla and 14 candidate divisions. On average, the most abundant phyla in all samples were Chloroflexi (Chloroflexota) (24.62%), followed by Proteobacteria (Pseudomonadota) (11.29%), Firmicutes (Bacillota) (10.73%), Crenarchaeota (Thermoproteota) (8.55%), and Acidobacteria (Acidobacteriota) (8.07%). At the genus level, a total of 286 known genera and candidate genera were mostly dominated by members of
    Discussion: In most of the stations, the Chao1 values at the deeper layers were comparable to the surface sediment samples denoting the high diversity in the subsurface of these ecosystems. Heatmap analysis based on the 100 most abundant OTUs, grouped the sampling stations according to their geographical location, placing together the two hottest stations (up to 99°C). This result indicates that this specific area within the active Kolumbo crater create a distinct niche, where microorganisms with adaptation strategies to withstand heat stresses can thrive, such as the endospore-forming Firmicutes.
    Language English
    Publishing date 2023-06-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2023.1188544
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Encapsulation of carotenoids extracted from halophilic Archaea in oil-in-water (O/W) micro- and nano-emulsions.

    Chaari, Marwa / Theochari, Ioanna / Papadimitriou, Vassiliki / Xenakis, Aristotelis / Ammar, Emna

    Colloids and surfaces. B, Biointerfaces

    2018  Volume 161, Page(s) 219–227

    Abstract: Carotenoids extracted from halophilc Archaea have potential health benefits. Their poor water-solubility and low bioavailability is a challenge to their incorporation into foods. The aim of this work was the carotenoids encapsulation into two oil-in- ... ...

    Abstract Carotenoids extracted from halophilc Archaea have potential health benefits. Their poor water-solubility and low bioavailability is a challenge to their incorporation into foods. The aim of this work was the carotenoids encapsulation into two oil-in-water (O/W) dispersions, to increase their use as functional food applications. A nanoemulsion produced by high pressure homogenization and a spontaneously formed microemulsion were conceived. The limonene was the dispersed oil phase, and mixtures of Triton X-100/Tween-80 (3:1) as emulsifiers and of water/glycerol (2:1) as the continuous aqueous phase. The microemulsion monophasic area was determined through the pseudo-ternary phase diagram. Dynamic Light Scattering was used for the structural characterization of the nano- and micro-emulsions in the presence of the carotenoids. Moreover, the radical scavenging activity of the encapsulated carotenoids was examined by Electron Paramagnetic Resonance spectroscopy. The results confirmed the delivery systems design effectiveness to encapsulate and stabilize the carotenoids for food applications.
    MeSH term(s) Archaea/chemistry ; Carotenoids/chemistry ; Cyclohexenes/chemistry ; Drug Delivery Systems/methods ; Electron Spin Resonance Spectroscopy ; Emulsions/chemistry ; Glycerol/chemistry ; Nanostructures/chemistry ; Octoxynol/chemistry ; Oils/chemistry ; Polysorbates/chemistry ; Solubility ; Surface-Active Agents/chemistry ; Terpenes/chemistry ; Thermodynamics ; Water/chemistry
    Chemical Substances Cyclohexenes ; Emulsions ; Oils ; Polysorbates ; Surface-Active Agents ; Terpenes ; Water (059QF0KO0R) ; Carotenoids (36-88-4) ; Octoxynol (9002-93-1) ; limonene (9MC3I34447) ; Glycerol (PDC6A3C0OX)
    Language English
    Publishing date 2018-01-01
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1500523-9
    ISSN 1873-4367 ; 0927-7765
    ISSN (online) 1873-4367
    ISSN 0927-7765
    DOI 10.1016/j.colsurfb.2017.10.042
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Nutraceutical phycocyanobilin binding to catalase protects the pigment from oxidation without affecting catalytic activity.

    Gligorijević, Nikola / Minić, Simeon / Radibratović, Milica / Papadimitriou, Vassiliki / Nedić, Olgica / Sotiroudis, Theodore G / Nikolić, Milan R

    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

    2021  Volume 251, Page(s) 119483

    Abstract: Phycocyanobilin is a dark blue linear tetrapyrrole chromophore covalently attached to protein subunits of phycobiliproteins present in the light-harvesting complexes of the cyanobacteria Arthrospira platensis (Spirulina "superfood"). It shows exceptional ...

    Abstract Phycocyanobilin is a dark blue linear tetrapyrrole chromophore covalently attached to protein subunits of phycobiliproteins present in the light-harvesting complexes of the cyanobacteria Arthrospira platensis (Spirulina "superfood"). It shows exceptional health-promoting properties and emerging use in various fields of bioscience and industry. This study aims to examine the mutual impact of phycocyanobilin interactions with catalase, a life-essential antioxidant enzyme. Fluorescence quenching experiments demonstrated moderate binding (K
    MeSH term(s) Catalase ; Dietary Supplements ; Phycobilins ; Phycocyanin ; Protein Binding ; Spirulina
    Chemical Substances Phycobilins ; Phycocyanin (11016-15-2) ; phycocyanobilin (36NUT04V2K) ; Catalase (EC 1.11.1.6)
    Language English
    Publishing date 2021-01-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 210413-1
    ISSN 1873-3557 ; 0370-8322 ; 0584-8539 ; 1386-1425
    ISSN (online) 1873-3557
    ISSN 0370-8322 ; 0584-8539 ; 1386-1425
    DOI 10.1016/j.saa.2021.119483
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Biological Evaluation of Oil-in-Water Microemulsions as Carriers of Benzothiophene Analogues for Dermal Applications.

    Theochari, Ioanna / Ilic, Tanja / Nicolic, Ines / Dobricic, Vladimir / Tenchiou, Alia / Papahatjis, Demetris / Savic, Snezana / Xenakis, Aristotelis / Papadimitriou, Vassiliki / Pletsa, Vasiliki

    Biomimetics (Basel, Switzerland)

    2021  Volume 6, Issue 1

    Abstract: During the last decade, many studies have been reported on the design and formulation of novel drug delivery systems proposed for dermal or transdermal administration. The efforts focus on the development of biocompatible nanodispersions that can be ... ...

    Abstract During the last decade, many studies have been reported on the design and formulation of novel drug delivery systems proposed for dermal or transdermal administration. The efforts focus on the development of biocompatible nanodispersions that can be delivered to the skin and treat severe skin disorders, including cancer. In this context, oil-in-water (O/W) microemulsions have been developed to encapsulate and deliver lipophilic bioactive molecules for dermal application. An O/W biocompatible microemulsion composed of PBS buffer, Tween 80, and triacetin was assessed for its efficacy as a drug carrier of DPS-2, a lead compound, initially designed in-house to inhibit BRAF
    Language English
    Publishing date 2021-01-27
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2313-7673
    ISSN (online) 2313-7673
    DOI 10.3390/biomimetics6010010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: What Factors Determine the Patients' Choice in Finding Their Office Urologist?

    Zachariou, Athanasios / Dimitriadis, Fotios / Papadimitriou, Vaios / Tsafrakidis, Petros / Haensel, Stefan M / Mamoulakis, Charalampos / Haas, Helmut

    Patient preference and adherence

    2021  Volume 15, Page(s) 2837–2843

    Abstract: Purpose: The present study aimed to investigate how patients identify a quality urologist in primary health care and how they determine and evaluate their provider's qualities before their first examination.: Patients and methods: A specific ... ...

    Abstract Purpose: The present study aimed to investigate how patients identify a quality urologist in primary health care and how they determine and evaluate their provider's qualities before their first examination.
    Patients and methods: A specific questionnaire (The ESUO Questionnaire) was prepared to describe the domains that influence the patient's evaluation and summarize the urologist related characteristics and behaviours that the patients estimate are more important. A total of 335 patients, over 18 years of age, presented in primary healthcare urology practice, completed the survey. The participants were divided into three age groups; 18-39 years of age (111 patients), 40-59 years of age (111 patients) and 113 patients 60 years of age and older.
    Results: The majority of patients (68.4%) selected that the urologist must be efficient and well trained. This attitude was primarily expressed in patients ≥60 years of age. Individuals under 60 years old stated that they expect a detailed examination and that the patient should be the urologist's priority. The majority of the patients evaluates friends or family's proposals concerning the urologist's quality primarily and believes that there is at least good quality of urological health care.
    Conclusion: Most patients evaluate primarily the effectiveness of the care they receive instead of the urologist's personality traits or personal relationships.
    Language English
    Publishing date 2021-12-17
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2455848-5
    ISSN 1177-889X
    ISSN 1177-889X
    DOI 10.2147/PPA.S342624
    Database MEDical Literature Analysis and Retrieval System OnLINE

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