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  1. Article: Orthoprothetische Versorgung einer Umkehrplastik

    Papadopoulos, A.

    Orthopädie-Technik

    2020  Volume 71, Issue 12, Page(s) 60

    Language German
    Document type Article
    ZDB-ID 207441-2
    ISSN 0340-5591
    Database Current Contents Medicine

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  2. Article: DIGITALISIERUNG. Innovative Methoden zur Digitalisierung von AWMP-Prozessen (Ecolab)

    Papadopoulos, A.

    Zentralsterilization

    2020  Volume 28, Issue Suppl.Okt., Page(s) 36

    Language German ; English
    Document type Article
    ZDB-ID 1174544-7
    ISSN 0942-6086
    Database Current Contents Medicine

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  3. Article: "3 Fragen an..." Aaron Papadopoulos

    Papadopoulos, Aaron

    Aseptica

    2022  Volume 28, Issue 2, Page(s) 24

    Language German ; English
    Document type Article
    ZDB-ID 1390610-0
    ISSN 1439-9016
    Database Current Contents Medicine

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    Zs.A 5137: Show issues Location:
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  4. Article: 226Ra/238U and 228Th/228Ra disequilibrium as weathering indices in beach sand sediments associated with granitoids from Cyclades. Greece

    Papadopoulos, A

    Applied geochemistry. 2019 Jan., v. 100

    2019  

    Abstract: Radioactive secular disequilibrium measured as the absolute difference from 1 of the 226Ra/238U and 228Ra/228Th ratios have been used to determine weathering extent. Twenty-eight samples from beach sands of Cyclades islands, all of them being the ... ...

    Abstract Radioactive secular disequilibrium measured as the absolute difference from 1 of the 226Ra/238U and 228Ra/228Th ratios have been used to determine weathering extent. Twenty-eight samples from beach sands of Cyclades islands, all of them being the weathering products of the local granitic plutons, are studied for their secular disequilibrium in both 238U and 232Th series (226Ra/238U and 228Th/228Ra respectively). The results are compared to weathering indices already in use worldwide and suggest a significant linear correlation of U-series disequilibrium with WIP (alkaline and alkaline-earth element leaching) and PWI (silica leaching) for the beach sands studied and significant non-linear correlations with CIA (chemical index of alteration) and PIA (plagioclase index of alteration). Considering only the heavy mineral enriched samples, significant correlations exist between U-series disequilibrium and CIA, CIW (chemical index of weathering) and PIA. Therefore, with an appropriate choice of the weathering index and samples both U-series and weathering index can recover the extent of chemical weathering. On the other hand, the use of Th-series disequilibrium as a weathering index is limited, due to 228Th and 228Ra geochemistry and especially due to their short radionuclide half-lives. U-series disequilibrium can therefore be used as a relatively sensitive weathering index in sediments consistent with CIA, CIW and PIA indices. However, the mineralogical composition must be considered. More specifically the mineral content of the sediments should involve considerable amounts of sensitive to weathering minerals (e.g. Fe-Mg minerals) as well as feldspars.
    Keywords geochemistry ; half life ; islands ; leaching ; mineral content ; plagioclase ; radionuclides ; radium ; sand ; silica ; thorium ; uranium ; weathering ; Greece
    Language English
    Dates of publication 2019-01
    Size p. 223-233.
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 1499242-5
    ISSN 0883-2927
    ISSN 0883-2927
    DOI 10.1016/j.apgeochem.2018.12.002
    Database NAL-Catalogue (AGRICOLA)

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  5. Article: Analysis of the effectiveness and the cost of hospitalization of patients with atrial fibrillation.

    Vogiatzis, I / Sdogkos, E / Pliatsika, M / Papadopoulos, A / Spahiu, A / Roditis, P

    Hippokratia

    2024  Volume 27, Issue 1, Page(s) 18–21

    Abstract: Introduction: Hospitalizations of patients with atrial fibrillation (AF) lead to an explosion of expenditure on the public health system or private health expenses in family budgets. This study aims to estimate the duration and the cost of ... ...

    Abstract Introduction: Hospitalizations of patients with atrial fibrillation (AF) lead to an explosion of expenditure on the public health system or private health expenses in family budgets. This study aims to estimate the duration and the cost of hospitalization for the public health system or the private cost to patients hospitalized after an AF episode.
    Material and methods: Two hundred thirty-five consecutive patients (141 men and 94 women with an average age of 71.91 ± 12.2 years) who presented with AF to the Emergency Department of the General Hospital of Veroia during a single year were studied. We assessed the possible causes of arrhythmia, the duration and outcome of hospitalization, and the cost of hospitalization. We estimated the total cost by adding the price of the drugs used to cardiovert and the money spent on the patient's hospitalization.
    Results: The average hospitalization time was 2.37 ± 1.17 days, and the average cost of hospitalization (total cost) was € 488.22 ± 170.34. There was a significant correlation between the severity of the episode and the total cost (r =0.78, p<0.0001), with 87.6 % of the total cost (€ 427.76 ± 135.86) being related to the cost of hospitalization (imaging, laboratory, hospitalization) and the rest to the drug therapy cost. Amiodarone (97 patients, 41.1 %), flecainide (52 patients, 22 %), propafenone (68 patients, 28.8 %), vernakalant (two patients, 0.8 %), and quinidine (eight patients, 3.4 %) were utilized.
    Conclusion: The average cost of hospital care in patients with AF is significantly related to the severity of the episode. Effective drug therapy to reduce AF-provoking factors, such as antihypertensive therapy, combined with cardiovascular disease prevention in general, could reduce the morbidity and costs of AF-related hospitalizations. HIPPOKRATIA 2023, 27 (1):18-21.
    Language English
    Publishing date 2024-03-12
    Publishing country Greece
    Document type Journal Article
    ZDB-ID 2491943-3
    ISSN 1790-8019 ; 1108-4189
    ISSN (online) 1790-8019
    ISSN 1108-4189
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  6. Article ; Online: Leveraging Unlabelled Data in Multiple-Instance Learning Problems for Improved Detection of Parkinsonian Tremor in Free-Living Conditions.

    Papadopoulos, Alexandros / Delopoulos, Anastasios

    IEEE journal of biomedical and health informatics

    2023  Volume 27, Issue 7, Page(s) 3569–3578

    Abstract: Data-driven approaches for remote detection of Parkinson's Disease and its motor symptoms have proliferated in recent years, owing to the potential clinical benefits of early diagnosis. The holy grail of such approaches is the free-living scenario, in ... ...

    Abstract Data-driven approaches for remote detection of Parkinson's Disease and its motor symptoms have proliferated in recent years, owing to the potential clinical benefits of early diagnosis. The holy grail of such approaches is the free-living scenario, in which data are collected continuously and unobtrusively during every day life. However, obtaining fine-grained ground-truth and remaining unobtrusive is a contradiction and therefore, the problem is usually addressed via multiple-instance learning. Yet for large scale studies, obtaining even the necessary coarse ground-truth is not trivial, as a complete neurological evaluation is required. In contrast, large scale collection of data without any ground-truth is much easier. Nevertheless, utilizing unlabelled data in a multiple-instance setting is not straightforward, as the topic has received very little research attention. Here we try to fill this gap by introducing a new method for combining semi-supervised with multiple-instance learning. Our approach builds on the Virtual Adversarial Training principle, a state-of-the-art approach for regular semi-supervised learning, which we adapt and modify appropriately for the multiple-instance setting. We first establish the validity of the proposed approach through proof-of-concept experiments on synthetic problems generated from two well-known benchmark datasets. We then move on to the actual task of detecting PD tremor from hand acceleration signals collected in-the-wild, but in the presence of additional completely unlabelled data. We show that by leveraging the unlabelled data of 454 subjects we can achieve large performance gains (up to 9% increase in F1-score) in per-subject tremor detection for a cohort of 45 subjects with known tremor ground-truth. In doing so, we confirm the validity of our approach on a real-world problem where the need for semi-supervised and multiple-instance learning arises naturally.
    MeSH term(s) Humans ; Tremor/diagnosis ; Social Conditions ; Parkinson Disease/diagnosis ; Supervised Machine Learning
    Language English
    Publishing date 2023-06-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2695320-1
    ISSN 2168-2208 ; 2168-2194
    ISSN (online) 2168-2208
    ISSN 2168-2194
    DOI 10.1109/JBHI.2023.3267095
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5483: Show issues Location:
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  7. Article ; Online: Trust in cervical screening and attributions of blame for interval cancers following a national controversy.

    Poluektova, Olga / Robertson, Deirdre A / Papadopoulos, Alexandros / Lunn, Peter D

    British journal of health psychology

    2024  

    Abstract: Objectives: This study investigated levels of trust and attributions of blame in connection with a cervical screening programme following a controversy related to the programme's audit, incorporating an experimental test of the effectiveness of new ... ...

    Abstract Objectives: This study investigated levels of trust and attributions of blame in connection with a cervical screening programme following a controversy related to the programme's audit, incorporating an experimental test of the effectiveness of new information materials.
    Design: We compared responses in Ireland (N = 872) to equivalent responses in Scotland (N = 400). Participants in Ireland were randomly assigned to either a treatment group that received the information materials or a control group that did not. Participants then responded to questions about their trust in cervical screening and to whom they would attribute blame in a range of scenarios describing women diagnosed with cervical cancer between screening rounds.
    Results: Results showed that the control group in Ireland had lower trust and attributed higher blame towards screening services than participants in Scotland. However, exposure to information materials in the treatment group improved trust and reduced blame.
    Conclusions: The findings suggest that public controversies influence perceptions of screening programmes and underscore the importance of transparent, choice-based communication in mitigating these effects. The findings have valuable implications for screening services worldwide as all screening programmes will have associated false negative and false positive results.
    Language English
    Publishing date 2024-05-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2026500-1
    ISSN 2044-8287 ; 1359-107X
    ISSN (online) 2044-8287
    ISSN 1359-107X
    DOI 10.1111/bjhp.12727
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  8. Book ; Online: Leveraging Unlabelled Data in Multiple-Instance Learning Problems for Improved Detection of Parkinsonian Tremor in Free-Living Conditions

    Papadopoulos, Alexandros / Delopoulos, Anastasios

    2023  

    Abstract: Data-driven approaches for remote detection of Parkinson's Disease and its motor symptoms have proliferated in recent years, owing to the potential clinical benefits of early diagnosis. The holy grail of such approaches is the free-living scenario, in ... ...

    Abstract Data-driven approaches for remote detection of Parkinson's Disease and its motor symptoms have proliferated in recent years, owing to the potential clinical benefits of early diagnosis. The holy grail of such approaches is the free-living scenario, in which data are collected continuously and unobtrusively during every day life. However, obtaining fine-grained ground-truth and remaining unobtrusive is a contradiction and therefore, the problem is usually addressed via multiple-instance learning. Yet for large scale studies, obtaining even the necessary coarse ground-truth is not trivial, as a complete neurological evaluation is required. In contrast, large scale collection of data without any ground-truth is much easier. Nevertheless, utilizing unlabelled data in a multiple-instance setting is not straightforward, as the topic has received very little research attention. Here we try to fill this gap by introducing a new method for combining semi-supervised with multiple-instance learning. Our approach builds on the Virtual Adversarial Training principle, a state-of-the-art approach for regular semi-supervised learning, which we adapt and modify appropriately for the multiple-instance setting. We first establish the validity of the proposed approach through proof-of-concept experiments on synthetic problems generated from two well-known benchmark datasets. We then move on to the actual task of detecting PD tremor from hand acceleration signals collected in-the-wild, but in the presence of additional completely unlabelled data. We show that by leveraging the unlabelled data of 454 subjects we can achieve large performance gains (up to 9% increase in F1-score) in per-subject tremor detection for a cohort of 45 subjects with known tremor ground-truth.

    Comment: A. Papadopoulos and A. Delopoulos, "Leveraging Unlabelled Data in Multiple-Instance Learning Problems for Improved Detection of Parkinsonian Tremor in Free-Living Conditions," in IEEE Journal of Biomedical and Health Informatics, doi:10.1109/JBHI.2023.3267095
    Keywords Computer Science - Machine Learning
    Subject code 006
    Publishing date 2023-04-29
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Exploring the double burden of malnutrition at the household level in the Philippines: Analysis of National Nutrition Survey data.

    Gaupholm, Josephine / Dodd, Warren / Papadopoulos, Andrew / Little, Matthew

    PloS one

    2023  Volume 18, Issue 7, Page(s) e0288402

    Abstract: Background: In the Philippines, the rising prevalence of obesity and related chronic diseases alongside persistent undernutrition presents a complex public health challenge. Understanding the patterns and dynamics of this 'double burden of malnutrition' ...

    Abstract Background: In the Philippines, the rising prevalence of obesity and related chronic diseases alongside persistent undernutrition presents a complex public health challenge. Understanding the patterns and dynamics of this 'double burden of malnutrition' (DBM) is crucial for developing effective intervention strategies. However, evidence of the occurrence of undernutrition and overnutrition within the same household is currently lacking.
    Methods: Using cross-sectional data from the 2013 Philippines National Nutrition Survey this study examined the prevalence of different typologies of household-level DBM from an analytical sample of 5,837 households and 25,417 individuals. Multivariable logistic regression was performed to identify factors associated with overall occurrence of intrahousehold DBM.
    Results: The overall prevalence of double burden households was 56% based on a comprehensive definition. The most common typology of intrahousehold DBM characterized in this study (% of all households) comprised households with at least one adult with overnutrition and at least one separate adult with undernutrition. Household size, wealth quintile, food insecurity, and household dietary diversity were all associated with household-level DBM. Double burden households were also influenced by head of household characteristics, including sex, level of education, employment status, and age.
    Conclusions: The findings from this study reveal that the coexistence of overnutrition and undernutrition at the household level is a major public health concern in the Philippines. Further comprehensive assessments of household-level manifestations of the DBM are needed to improve our understanding of the trends and drivers of this phenomenon in order to develop better targeted interventions.
    MeSH term(s) Adult ; Humans ; Philippines/epidemiology ; Cross-Sectional Studies ; Malnutrition/epidemiology ; Nutritional Status ; Family Characteristics ; Overnutrition/epidemiology ; Nutrition Surveys ; Prevalence ; Socioeconomic Factors ; Overweight/epidemiology
    Language English
    Publishing date 2023-07-17
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0288402
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  10. Article: Low-Intensity Pulsed Ultrasound Treatment for Non-unions of Long Bone Fractures in a Scottish District General Hospital.

    Haller, Petra / Nunag, Perrico / Papadopoulos, Antonios

    Cureus

    2023  Volume 15, Issue 1, Page(s) e34159

    Abstract: Objective: Despite advances in treatment, the management of fracture non-union remains a challenging and complex problem in orthopaedics. Low-intensity pulsed ultrasound (LIPUS) treatment has been shown to be an effective, non-invasive, affordable ... ...

    Abstract Objective: Despite advances in treatment, the management of fracture non-union remains a challenging and complex problem in orthopaedics. Low-intensity pulsed ultrasound (LIPUS) treatment has been shown to be an effective, non-invasive, affordable treatment option. This treatment was evaluated in a Scottish district hospital over a nine-year period, which included the COVID-19 pandemic.
    Materials and methods: This submission describes a case series at Dr Gray's Hospital in Scotland, 18 patients in whom fracture non-union was treated using LIPUS.
    Results: An overall healing rate of 94% was achieved. Exogen™ (Bioventus LLC, NC, USA) proved to be most successful in oligotrophic non-union. No observed patient demographic appeared predictive of outcome. LIPUS treatment failed in one case. No significant adverse effects of LIPUS were detected.
    Conclusion: LIPUS represents a useful, cost-effective potential alternative to revision surgery. LIPUS may therefore be the preferred treatment when surgical intervention and face-to-face interactions are to be minimised, as during the COVID-19 pandemic.
    Language English
    Publishing date 2023-01-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.34159
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