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  1. AU="Papadopoulos, G"
  2. AU="Boughen, Santiago"
  3. AU="Brink, P. L."

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  1. Conference proceedings ; Online: Historical earthquakes, rupture zones and the earthquake cycle along the East Anatolian Fault

    Triantafyllou, I. / Papadopoulos, G.

    XXVIII General Assembly of the International Union of Geodesy and Geophysics (IUGG)

    2023  

    Abstract: The region of the East Anatolian Fault (EAF) experienced several strong earthquakes during the instrumental period of seismology, i.e. after AD 1900. However, the devastating earthquake (Mw7.8) of 6 February 2023, that ruptured along the EAF, is the ... ...

    Abstract The region of the East Anatolian Fault (EAF) experienced several strong earthquakes during the instrumental period of seismology, i.e. after AD 1900. However, the devastating earthquake (Mw7.8) of 6 February 2023, that ruptured along the EAF, is the first to occur with such a large magnitude in that time interval. Then, some questions of fundamental importance for the earthquake cycle in the EAF raise. When earthquakes of similarly large magnitudes occurred in the past? Which segments of the EAF ruptured? What is the mean repeat time of the large EAF earthquakes? To respond to such challenging issues we organized a data base of historical earthquakes that caused significant damage in the region of EAF and assigned macroseismic intensities in terms of MMI scale. Earthquake magnitudes were calculated from empirical magnitude/intensity relationships. Mapping of lateral rupture zones along the EAF was based on higher degree isoseismal curves (e.g. degree VIII) and on evidence of surface-fault traces and other ground failures. Preliminary results showed that rupture zones of the large magnitude earthquakes abut and do not overlap, while the repeat times are of the order of several hundred years.
    Subject code 550
    Language English
    Publishing date 2023-07-11
    Publishing country de
    Document type Conference proceedings ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Conference proceedings: Augenärztliche Notfälle – am Telefon und an der Anmeldung

    Papadopoulos, Gudrun

    2022  , Page(s) OAPV 5.1

    Event/congress 34. Internationaler Kongress der Deutschen Ophthalmochirurgen; Nürnberg; 2022
    Keywords Medizin, Gesundheit
    Publishing date 2022-06-03
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/22doc025
    Database German Medical Science

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  3. Conference proceedings ; Online: Probabilistic tsunami risk assessment from historical impact files

    Papadopoulos, G. / Triantafyllou, I. / Kijko, A.

    XXVIII General Assembly of the International Union of Geodesy and Geophysics (IUGG)

    Mediterranean and connected seas

    2023  

    Abstract: Probabilistic tsunami risk is assessed using a procedure that allows including mixed data from the instrumental part of tsunami catalogs, and data from the highly incomplete and uncertain pre-instrumental part. Such a model was used successfully for ... ...

    Abstract Probabilistic tsunami risk is assessed using a procedure that allows including mixed data from the instrumental part of tsunami catalogs, and data from the highly incomplete and uncertain pre-instrumental part. Such a model was used successfully for hazard assessment of earthquakes (Kijko et al., 2016) and tsunamis (Smit et al., 2019), considering seismic magnitude and tsunami height as metrics of the respective hazards. We applied this technique using catalogs for the basins of the Mediterranean and connected seas. Wave impact (destructiveness) is expressed in terms of tsunami intensity, K, i.e., a risk metric on the Papadopoulos-Imamura 12-degree scale. Risk level is assessed in terms of probabilities of exceedance and return periods of certain intensity levels in specific time frames. Tests and sensitivity analysis showed that using complete data sets generally provided more realistic results than using entire data sets. Our results indicated that the risk level depended on the seismicity level and not on the size of the investigated basin. The highest tsunami risk level was found in the eastern Mediterranean, with a significantly lower risk in the western Mediterranean. In the Marmara Sea, the tsunami risk was low, and the lowest was in the Black Sea. The risk in the Corinth Gulf in Central Greece was comparable to that of WM. The return period of damaging tsunamis was 22 years in the entire Mediterranean basin and from 31 to 1 660 years in the various sub-basins.
    Subject code 332
    Language English
    Publishing date 2023-07-11
    Publishing country de
    Document type Conference proceedings ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  4. Article ; Online: Evaluation and validation of a patient-reported quality-of-life questionnaire for Parkinson's disease.

    Stathis, Pantelis / Papadopoulos, George

    Journal of patient-reported outcomes

    2022  Volume 6, Issue 1, Page(s) 17

    Abstract: Background: Parkinson's disease (PD) is a chronic, progressive illness with a profound impact on the health-related quality of life (HRQoL). Disease-specific patient-reported HRQoL measures, such as PDQ-39 and its short version PDQ-8, are increasingly ... ...

    Abstract Background: Parkinson's disease (PD) is a chronic, progressive illness with a profound impact on the health-related quality of life (HRQoL). Disease-specific patient-reported HRQoL measures, such as PDQ-39 and its short version PDQ-8, are increasingly used in clinical practice to address the consequences of PD on everyday life. Due to limitations in the content, especially in non-motor symptoms and sleep disturbances of PDQ-8, PDQoL7, a 7-item, short-term, self-reported, PD-specific HRQoL questionnaire was developed.
    Methods: A representative sample of 60 adults with idiopathic PD completed the PDQoL7 questionnaire and the existing validated PDQ-8 and EQ-5D-5L questionnaires (all in Greek).
    Results: PDQoL7 summary index strongly correlated with PDQ-8 (r
    Conclusions: PDQoL7 is an acceptable, easy to use, valid and reliable tool for the determination of HRQoL in PD patients that is potentially more comprehensive than PDQ-8 based on the available evidence. PDQoL7 could allow for a more thorough evaluation of the impact of PD and contribute to guiding healthcare decisions. This will be confirmed in subsequent analysis on larger patient cohorts.
    Language English
    Publishing date 2022-03-02
    Publishing country Germany
    Document type Journal Article
    ISSN 2509-8020
    ISSN (online) 2509-8020
    DOI 10.1186/s41687-022-00427-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Lipidomic Analysis of Liver and Adipose Tissue in a High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease Mice Model Reveals Alterations in Lipid Metabolism by Weight Loss and Aerobic Exercise.

    Mouskeftara, Thomai / Deda, Olga / Papadopoulos, Grigorios / Chatzigeorgiou, Antonios / Gika, Helen

    Molecules (Basel, Switzerland)

    2024  Volume 29, Issue 7

    Abstract: Detailed investigation of the lipidome remodeling upon normal weight conditions, obesity, or weight loss, as well as the influence of physical activity, can help to understand the mechanisms underlying dyslipidemia in metabolic conditions correlated to ... ...

    Abstract Detailed investigation of the lipidome remodeling upon normal weight conditions, obesity, or weight loss, as well as the influence of physical activity, can help to understand the mechanisms underlying dyslipidemia in metabolic conditions correlated to the emergence and progression of non-alcoholic fatty liver disease (NAFLD). C57BL/6 male mice were fed a normal diet (ND) or a high-fat diet (HFD) for 20 weeks. Subgroups within the high-fat diet (HFD) group underwent different interventions: some engaged in exercise (HFDex), others were subjected to weight loss (WL) by changing from the HFD to ND, and some underwent a combination of weight loss and exercise (WLex) during the final 8 weeks of the 20-week feeding period. To support our understanding, not only tissue-specific lipid remodeling mechanisms but also the cross-talk between different tissues and their impact on the systemic regulation of lipid metabolism are essential. Exercise and weight loss-induced specific adaptations in the liver and visceral adipose tissue lipidomes of mice were explored by the UPLC-TOF-MS/MS untargeted lipidomics methodology. Lipidomic signatures of ND and HFD-fed mice undergoing weight loss were compared with animals with and without physical exercise. Several lipid classes were identified as contributing factors in the discrimination of the groups by multivariate analysis models, such as glycerolipids, glycerophospholipids, sphingolipids, and fatty acids, with respect to liver samples, whereas triglycerides were the only lipid class identified in visceral adipose tissue. Lipids found to be dysregulated in HFD animals are related to well-established pathways involved in the biosynthesis of PC, PE, and TG metabolism. These show a reversing trend back to basic levels of ND when animals change to a normal diet after 12 weeks, whereas the impact of exercise, though in some cases it slightly enhances the reversing trend, is not clear.
    MeSH term(s) Male ; Animals ; Mice ; Mice, Inbred C57BL ; Non-alcoholic Fatty Liver Disease/etiology ; Lipidomics ; Lipid Metabolism ; Diet, High-Fat/adverse effects ; Tandem Mass Spectrometry ; Adipose Tissue ; Fatty Acids ; Weight Loss
    Chemical Substances Fatty Acids
    Language English
    Publishing date 2024-03-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules29071494
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.MO 81: Show issues

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  6. Article ; Online: Apraxia Patterns for the Differentiation between Alzheimer's Disease and Frontotemporal Dementia Variants.

    Papadopoulos, Georgios / Parissis, Dimitrios / Gotzamani-Psarrakou, Anna / Ioannidis, Panagiotis

    Medicina (Kaunas, Lithuania)

    2024  Volume 60, Issue 3

    Abstract: Background and ... ...

    Abstract Background and Objectives
    MeSH term(s) Adult ; Humans ; Alzheimer Disease/diagnosis ; Frontotemporal Dementia/diagnosis ; Frontotemporal Dementia/pathology ; Frontotemporal Dementia/psychology ; Apraxias/diagnosis ; Cognitive Dysfunction ; Neuropsychological Tests
    Language English
    Publishing date 2024-03-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina60030435
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6270: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  7. Conference proceedings: Notfalltelefon und Dringlichkeit

    Papadopoulos, Gudrun

    2019  , Page(s) OAPV 10.2

    Event/congress 32. Internationaler Kongress der Deutschen Ophthalmochirurgen; Nürnberg; 2019
    Keywords Medizin, Gesundheit
    Publishing date 2019-05-14
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/19doc031
    Database German Medical Science

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  8. Article: Alternative Crops for the European Tobacco Industry: A Systematic Review.

    Mavroeidis, Antonios / Stavropoulos, Panteleimon / Papadopoulos, George / Tsela, Aikaterini / Roussis, Ioannis / Kakabouki, Ioanna

    Plants (Basel, Switzerland)

    2024  Volume 13, Issue 2

    Abstract: Tobacco ( ...

    Abstract Tobacco (
    Language English
    Publishing date 2024-01-15
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2704341-1
    ISSN 2223-7747
    ISSN 2223-7747
    DOI 10.3390/plants13020236
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Food Safety and Management System Audits in Food Retail Chain Stores in Greece.

    Psomatakis, Michalis / Papadimitriou, Konstantinos / Souliotis, Andreas / Drosinos, Eleftherios H / Papadopoulos, Georgios

    Foods (Basel, Switzerland)

    2024  Volume 13, Issue 3

    Abstract: The present study aimed to assess the performance of food safety management systems in food retail stores via audits to reveal potential areas of improvement and to find out possible corrective actions to suggest to the top management. Two cycles of on- ... ...

    Abstract The present study aimed to assess the performance of food safety management systems in food retail stores via audits to reveal potential areas of improvement and to find out possible corrective actions to suggest to the top management. Two cycles of on-site audits took place in 106 stores to assess the requirements and hygiene conditions. After the first cycle of audits, improvements were suggested to the top management, and a second cycle of audits took place after a reasonable time. In the checklist, we recorded the temperatures of retail refrigerators and the scores from the inspection of hygiene and HACCP documentation. In the A' audit, the percentage of stores that had higher temperatures than the critical limits was equal to 51%, and those temperatures occurred in the refrigerators for salads, followed by the refrigerators for deli meat, yogurts and desserts. In the B' audit, only the refrigerators for salads exhibited percentages that were statistically significant lower (
    Language English
    Publishing date 2024-02-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods13030457
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Τ cell-mediated adaptive immunity in the transition from metabolic dysfunction-associated steatohepatitis to hepatocellular carcinoma.

    Papadopoulos, Grigorios / Giannousi, Eirini / Avdi, Aikaterini P / Velliou, Rallia-Iliana / Nikolakopoulou, Polyxeni / Chatzigeorgiou, Antonios

    Frontiers in cell and developmental biology

    2024  Volume 12, Page(s) 1343806

    Abstract: Metabolic dysfunction-associated steatohepatitis (MASH) is the progressed version of metabolic dysfunction-associated steatotic liver disease (MASLD) characterized by inflammation and fibrosis, but also a pathophysiological "hub" that favors the ... ...

    Abstract Metabolic dysfunction-associated steatohepatitis (MASH) is the progressed version of metabolic dysfunction-associated steatotic liver disease (MASLD) characterized by inflammation and fibrosis, but also a pathophysiological "hub" that favors the emergence of liver malignancies. Current research efforts aim to identify risk factors, discover disease biomarkers, and aid patient stratification in the context of MASH-induced hepatocellular carcinoma (HCC), the most prevalent cancer among MASLD patients. To investigate the tumorigenic transition in MASH-induced HCC, researchers predominantly exploit preclinical animal-based MASH models and studies based on archived human biopsies and clinical trials. Recapitulating the immune response during tumor development and progression is vital to obtain mechanistic insights into MASH-induced HCC. Notably, the advanced complexity behind MASLD and MASH pathogenesis shifted the research focus towards innate immunity, a fundamental element of the hepatic immune niche that is usually altered robustly in the course of liver disease. During the last few years, however, there has been an increasing interest for deciphering the role of adaptive immunity in MASH-induced HCC, particularly regarding the functions of the various T cell populations. To effectively understand the specific role of T cells in MASH-induced HCC development, scientists should urgently fill the current knowledge gaps in this field. Pinpointing the metabolic signature, sketching the immune landscape, and characterizing the cellular interactions and dynamics of the specific T cells within the MASH-HCC liver are essential to unravel the mechanisms that adaptive immunity exploits to enable the emergence and progression of this cancer. To this end, our review aims to summarize the current state of research regarding the T cell functions linked to MASH-induced HCC.
    Language English
    Publishing date 2024-05-07
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2737824-X
    ISSN 2296-634X
    ISSN 2296-634X
    DOI 10.3389/fcell.2024.1343806
    Database MEDical Literature Analysis and Retrieval System OnLINE

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