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  1. Article: Akuttherapie der aortoösophagealen und aortoenteralen Fistel. Gastrointestinale Blutungen. Die aortoösophageale und aortoenterale Fistel sind seltene Ursachen der gastrointestinalen Blutung. Die niedrige Inzidenz kann Ursache für verzögerte Diagnosestellung und erhöhte Mortalität sein

    Papazoglou, Dimitrios David

    Swiss medical forum

    2022  Volume 22, Issue 44, in: "Schweiz. Ärztezeitung, 103,44, Page(s) –

    Language German
    Document type Article
    ZDB-ID 2220114-2
    ISSN 1424-3784
    Database Current Contents Medicine

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  2. Article ; Online: Cutaneous Manifestations in Patients with SARS-CoV-2 Infections.

    Petrakis, Vasilios / Panagopoulos, Periklis / Terzi, Irene / Papazoglou, Dimitrios

    Acta dermatovenerologica Croatica : ADC

    2023  Volume 30, Issue 4, Page(s) 216–219

    Abstract: While SARS-CoV-2 is known to cause pneumonia and acute respiratory distress syndrome (ARDS), many extrapulmonary manifestations of COVID-19 have also been observed. Cutaneous manifestations including erythematous rash, urticaria, and chickenpox-like ... ...

    Abstract While SARS-CoV-2 is known to cause pneumonia and acute respiratory distress syndrome (ARDS), many extrapulmonary manifestations of COVID-19 have also been observed. Cutaneous manifestations including erythematous rash, urticaria, and chickenpox-like vesicles have been described in patients with SARS-CoV-2. Six patients, two men and four women, in the age group of 50 to 60 years old, hospitalized with SARS-CoV-2 infection confirmed with real-time polymerase chain reaction (real-time PCR) presented cutaneous manifestations. The rash was confluent, spotty, centrifugal, and non-itchy on the head and torso. It was not hemorrhagic, and no crust or blisters were observed. The results of laboratory tests were normal, and the rash disappeared on its own. Several cases of cutaneous manifestations have been reported in patients with SARS-CoV-2 infection. Further studies are needed in order to assess the skin lesions and determine their association with COVID-19.
    MeSH term(s) Male ; Humans ; Female ; Middle Aged ; COVID-19/complications ; SARS-CoV-2 ; Skin Diseases/complications ; Exanthema/complications ; Urticaria ; Blister
    Language English
    Publishing date 2023-03-08
    Publishing country Croatia
    Document type Journal Article
    ZDB-ID 1180727-1
    ISSN 1847-6538 ; 1330-027X
    ISSN (online) 1847-6538
    ISSN 1330-027X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Physician-modified versus chimney endografting for pararenal aortic aneurysms: a systematic review and meta-analysis.

    Karaolanis, Georgios I / Papazoglou, Dimitrios D / Donas, Konstantinos P / Helfenstein, Fabrice / Kotelis, Drosos / Makaloski, Vladimir

    The Journal of cardiovascular surgery

    2024  Volume 65, Issue 2, Page(s) 124–131

    Abstract: Introduction: We performed a systematic review and meta-analysis to assess the existing published evidence regarding the safety and efficacy of the endovascular aortic repair with chimney technique (ch-EVAR) and physician-modified stent-grafts (PMSGs) ... ...

    Abstract Introduction: We performed a systematic review and meta-analysis to assess the existing published evidence regarding the safety and efficacy of the endovascular aortic repair with chimney technique (ch-EVAR) and physician-modified stent-grafts (PMSGs) for the treatment of pararenal aortic aneurysm repair.
    Evidence acquisition: A systematic search of all relevant studies reported until October 2023 according to the PRISMA (preferred reporting items for systematic reviews and meta-analyses) guidelines was performed. The pooled 30-day mortality, peri- and postoperative complication rates were estimated using fixed or random effect methods.
    Evidence synthesis: A total of 679 study titles were identified by the initial search strategy, of which 16 were considered eligible for inclusion in the meta-analysis. A total of 1094 patients (ch-EVAR N.=861 and PMSG N.=233) (90% male) were identified. The pooled 30-day mortality rate was 3.4% for ch-EVAR and 2.6% for PMSG. The major adverse events (MAE) in the early period was 14.7% for ch-EVAR and 18.5% PMSG, respectively. Higher occlusion rate was observed of the chimney stents grafts (8.2%) than the bridging stents (1.4%) during the follow-up period.
    Conclusions: Ch-EVAR and physician-modified technology are safe with low 30-day mortality in elective settings for pararenal aortic aneurysms repair. No significant differences were seen between the two surgical methods regarding the early major adverse events rate. However, higher occlusion rate for the chimneys can be expected over time.
    MeSH term(s) Humans ; Endovascular Procedures/adverse effects ; Endovascular Procedures/instrumentation ; Endovascular Procedures/mortality ; Endovascular Procedures/methods ; Blood Vessel Prosthesis Implantation/adverse effects ; Blood Vessel Prosthesis Implantation/instrumentation ; Blood Vessel Prosthesis Implantation/mortality ; Blood Vessel Prosthesis ; Stents ; Treatment Outcome ; Aortic Aneurysm, Abdominal/surgery ; Aortic Aneurysm, Abdominal/mortality ; Aortic Aneurysm, Abdominal/diagnostic imaging ; Postoperative Complications/etiology ; Risk Factors ; Prosthesis Design ; Male ; Female ; Aged ; Time Factors ; Risk Assessment ; Middle Aged
    Language English
    Publishing date 2024-04-18
    Publishing country Italy
    Document type Systematic Review ; Meta-Analysis ; Journal Article
    ZDB-ID 80143-4
    ISSN 1827-191X ; 0021-9509
    ISSN (online) 1827-191X
    ISSN 0021-9509
    DOI 10.23736/S0021-9509.24.12995-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Fasting Plasma Glucose Increase and Neutrophil-to-Lymphocyte Ratio as Risk Predictors of Clinical Outcome of COVID-19 Pneumonia in Type 2 Diabetes Mellitus.

    Petrakis, Vasilios / Panagopoulos, Periklis / Trypsianis, Grigorios / Papazoglou, Dimitrios / Papanas, Nikolaos

    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association

    2023  Volume 131, Issue 4, Page(s) 194–197

    Abstract: Aim of the study: To evaluate fasting plasma glucose (FPG) increase and neutrophil-to-lymphocyte ratio (NLR) as risk predictors of severe clinical outcome of COVID-19 pneumonia in type 2 diabetes mellitus (T2DM) hospitalised patients.: Patients and ... ...

    Abstract Aim of the study: To evaluate fasting plasma glucose (FPG) increase and neutrophil-to-lymphocyte ratio (NLR) as risk predictors of severe clinical outcome of COVID-19 pneumonia in type 2 diabetes mellitus (T2DM) hospitalised patients.
    Patients and methods: Type 2 diabetes mellitus (T2DM) patients hospitalised between March 2020 and February 2021 were studied retrospectively. The NLR ratio at admission and FPG increase (day 7, day with maximal FPG) were evaluated in association with the clinical progression of SARS-CoV-2 infection.
    Results: Three hundred patients (165 men, 135 women) were included in the study. The mean age was 67.17±8.65 years. Severe COVID-19 pneumonia was diagnosed in 170 patients (56.7%). Fifty-four patients (18%) were intubated and 49 (16.3%) died. Greater increase in FPG (79.5 vs. 44.5 mg/dL for day 1-7, p<0.001; and 113.5 vs. 75 mg/dL for day 1-day with maximum glucose value, p<0.001) and higher NLR at admission (10.65 vs. 6.85) were seen in patients with need of high-flow oxygen compared to those without need, and they were associated with a higher probability of intubation and death.
    Conclusion: FPG increase and NLR could be significant risk predictors of severe COVID-19 pneumonia in T2DM hospitalised patients.
    MeSH term(s) Male ; Humans ; Female ; Middle Aged ; Aged ; COVID-19/complications ; Diabetes Mellitus, Type 2/complications ; Blood Glucose ; Retrospective Studies ; Neutrophils ; SARS-CoV-2 ; Fasting ; Lymphocytes
    Chemical Substances Blood Glucose
    Language English
    Publishing date 2023-01-09
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1225416-2
    ISSN 1439-3646 ; 0947-7349
    ISSN (online) 1439-3646
    ISSN 0947-7349
    DOI 10.1055/a-2009-6937
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The Antiviral Effect of Nirmatrelvir/Ritonavir during COVID-19 Pandemic Real-World Data.

    Petrakis, Vasilios / Rafailidis, Petros / Trypsianis, Grigorios / Papazoglou, Dimitrios / Panagopoulos, Periklis

    Viruses

    2023  Volume 15, Issue 4

    Abstract: Introduction: Vaccination against SARS-CoV-2 and the prevalence of Omicron variants have reduced the risk of the severe clinical progress of COVID-19. However, the risk of breakthrough infections has increased, and early administration of an effective ... ...

    Abstract Introduction: Vaccination against SARS-CoV-2 and the prevalence of Omicron variants have reduced the risk of the severe clinical progress of COVID-19. However, the risk of breakthrough infections has increased, and early administration of an effective antiviral treatment is significant in order to prevent the severe progression of COVID-19 in vulnerable patients with comorbidities.
    Patients and methods: Adults with confirmed SARS-CoV-2 infection were included in a matched-pair retrospective study based on age, gender, comorbidities and vaccination status. They were divided into two groups: group A (n = 200) consisted of outpatients at increased risk of severe clinical progress who were treated with nirmatrelvir/ritonavir and group B (n = 200) consisted of non-hospitalized patients who did not receive antiviral treatment. Demographic data, clinical outcome (death, intubation), days of hospitalization, time for recovery, adverse events and treatment compliance were reported.
    Results: The median age (75.24 ± 13.12 years in the study group and 76.91 ± 14.02 years in the comparison group) and the proportion of males (59% vs. 60.5%, respectively) were similar between the two groups. A total of 6.5% of patients in group A and 10.5% in group B were unvaccinated against SARS-CoV-2. Three patients from group A (1.5%) and one hundred eleven (55.5%) from group B required hospitalization. The duration of hospitalization (3 days vs. 10 days in group B,
    Conclusion: Oral treatment with nirmatrelvir/ritonavir in high-risk non-hospitalized patients was safe and effective in preventing the severe clinical progress of COVID-19 pneumonia. Early administration of antiviral agents in vulnerable outpatients combined with a full vaccination scheme is significant in order to avoid hospitalization and severe clinical outcomes.
    MeSH term(s) Adult ; Male ; Humans ; Middle Aged ; Aged ; Aged, 80 and over ; COVID-19/epidemiology ; SARS-CoV-2 ; Ritonavir/therapeutic use ; Pandemics ; Retrospective Studies ; COVID-19 Drug Treatment ; Antiviral Agents/therapeutic use
    Chemical Substances nirmatrelvir (7R9A5P7H32) ; Ritonavir (O3J8G9O825) ; Antiviral Agents
    Language English
    Publishing date 2023-04-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v15040976
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Remission of refractory Crohn's disease with anti-IL-12/23 therapy in a patient undergoing hemodialysis: A case report.

    Spathakis, Michail / Filidou, Eirini / Kolios, George / Papazoglou, Dimitrios / Vradelis, Stergios

    Hemodialysis international. International Symposium on Home Hemodialysis

    2023  Volume 27, Issue 3, Page(s) E41–E44

    Abstract: Crohn's disease is a relapsing chronic inflammatory condition of the intestine with increasing prevalence around the world. Biologic therapies are currently widely used and have proved safe and effective in treating moderate to severe Crohn's disease. ... ...

    Abstract Crohn's disease is a relapsing chronic inflammatory condition of the intestine with increasing prevalence around the world. Biologic therapies are currently widely used and have proved safe and effective in treating moderate to severe Crohn's disease. However, contemporary bibliography contains little information about the use of these drugs in patients with end-stage renal disease undergoing hemodialysis. Here we present a case of a 47-year-old female patient with treatment-refractory Crohn's disease on hemodialysis. In this patient, treatment with the anti-IL-12/23 receptor antibody ustekinumab was effective in inducing and maintaining remission while being safe in administering throughout hemodialysis.
    MeSH term(s) Female ; Humans ; Middle Aged ; Crohn Disease/complications ; Crohn Disease/drug therapy ; Interleukin-12/therapeutic use ; Remission Induction ; Renal Dialysis ; Ustekinumab/therapeutic use ; Treatment Outcome
    Chemical Substances Interleukin-12 (187348-17-0) ; Ustekinumab (FU77B4U5Z0)
    Language English
    Publishing date 2023-06-14
    Publishing country Canada
    Document type Case Reports
    ZDB-ID 2192458-2
    ISSN 1542-4758 ; 1492-7535
    ISSN (online) 1542-4758
    ISSN 1492-7535
    DOI 10.1111/hdi.13106
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Lysophospholipid Metabolism and Signalling in Non-Alcoholic Fatty Liver Disease.

    Papadopoulos, Charalambos / Tentes, Ioannis / Papazoglou, Dimitrios / Anagnostopoulos, Konstantinos

    Folia medica

    2022  Volume 64, Issue 1, Page(s) 7–12

    Abstract: Non-alcoholic liver disease (NAFLD) constitutes a global health pandemic. It is estimated that about 25% of the world's population suffers from NAFLD. In the long-term, a subgroup of the patients can develop inflammation and fibrosis. The end result in ... ...

    Abstract Non-alcoholic liver disease (NAFLD) constitutes a global health pandemic. It is estimated that about 25% of the world's population suffers from NAFLD. In the long-term, a subgroup of the patients can develop inflammation and fibrosis. The end result in some cases is cirrhosis and even liver-related death. The epidemiology and natural history of NAFLD lead to extreme financial costs.
    MeSH term(s) Humans ; Liver Cirrhosis ; Lysophospholipids ; Non-alcoholic Fatty Liver Disease/epidemiology ; Non-alcoholic Fatty Liver Disease/metabolism
    Chemical Substances Lysophospholipids
    Language English
    Publishing date 2022-07-18
    Publishing country Bulgaria
    Document type Journal Article
    ZDB-ID 300275-5
    ISSN 1314-2143 ; 0430-8638 ; 0204-8043
    ISSN (online) 1314-2143
    ISSN 0430-8638 ; 0204-8043
    DOI 10.3897/folmed.64.e59297
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Early 3-day course of remdesivir in vaccinated outpatients with SARS-CoV-2 infection. A success story.

    Panagopoulos, Periklis / Petrakis, Vasilis / Trypsianis, Grigorios / Papazoglou, Dimitrios

    Journal of chemotherapy (Florence, Italy)

    2022  Volume 34, Issue 8, Page(s) 550–553

    Abstract: A number of treatment options have been evaluated in order to prevent the severe progression of COVID-19 pneumonia eventually in patients with increased risk due to comorbidities. Remdesivir for a 3-day outpatient course has been associated with a ... ...

    Abstract A number of treatment options have been evaluated in order to prevent the severe progression of COVID-19 pneumonia eventually in patients with increased risk due to comorbidities. Remdesivir for a 3-day outpatient course has been associated with a significant lower risk of hospitalization or death. A matched-pair retrospective study was conducted in Department of Infectious Diseases of University General Hospital of Alexandroupolis in order to evaluate the role of remdesivir and vaccination in preventing severe clinical outcome. Nonhospitalized vaccinated patients with a 3-day course of remdesivir had a 75% lower possibility of hospitalization and 95% of respiratory failure. Nobody was intubated or died and the duration of hospital stay was limited (4 day s vs. 10 days). Vaccination and a 3-day course of remdesivir in high risk nonhospitalized patients prevented significantly severe clinical progress of COVID-19 pneumonia.
    MeSH term(s) Humans ; COVID-19/drug therapy ; SARS-CoV-2 ; Outpatients ; Retrospective Studies ; Antiviral Agents/adverse effects ; Treatment Outcome
    Chemical Substances remdesivir (3QKI37EEHE) ; Antiviral Agents
    Language English
    Publishing date 2022-07-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 1036294-0
    ISSN 1973-9478 ; 1120-009X
    ISSN (online) 1973-9478
    ISSN 1120-009X
    DOI 10.1080/1120009X.2022.2099693
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Novel Surgeon-Modified Fenestrated Iliac Stent Graft.

    Jungi, Silvan / Papazoglou, Dimitrios D / Chan, Hon-Lai / Schmidli, Jürg / Makaloski, Vladimir

    Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists

    2023  , Page(s) 15266028231173311

    Abstract: Purpose: We describe the feasibility and early results of a novel endovascular approach with a surgeon-modified fenestrated iliac stent graft to preserve pelvic perfusion in patients with iliac aneurysms not suitable for iliac branch devices (IBDs).: ... ...

    Abstract Purpose: We describe the feasibility and early results of a novel endovascular approach with a surgeon-modified fenestrated iliac stent graft to preserve pelvic perfusion in patients with iliac aneurysms not suitable for iliac branch devices (IBDs).
    Technique: Seven high-risk patients, median age 76 years (range 63-83), with a complex aortoiliac anatomy with contraindications for commercially available IBDs were treated with a novel surgeon-modified fenestrated iliac stent graft between August 2020 and November 2021. The modified device was built using an iliac limb stent graft (Endurant II Stent Graft; Medtronic), which was partially deployed, surgically fenestrated with a scalpel, reinforced, re-sheathed, and inserted via femoral access. The internal iliac artery was cannulated and bridged with a covered stent. Technical success rate was 100%. After a median follow-up period of 10 months, there was 1 type II endoleak and no migrations, stent fractures, or loss of device integrity. One iliac limb occlusion occurred after 7 months, which needed a secondary endovascular intervention, restoring patency.
    Conclusion: Surgeon-modified fenestrated iliac stent graft is feasible and might be used as an alternative in patients with a complex iliac anatomy not suitable to commercially available IBDs. Long-term follow-up is needed to evaluate stent graft patency and potential complications.
    Clinical impact: Surgeon modified fenetrated iliac stent grafts might be a promising alternative to iliac branch devices, extending endovascular solutions to a broader patient population with complex aorto-iliac anatomies preserving antegrade internal iliac artery perfusion. It is possible to treat small iliac bifurcations and large angulations of the iliac bifurcation safely and there is no need for a contralateral or upper-extremity access.
    Language English
    Publishing date 2023-05-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2006618-1
    ISSN 1545-1550 ; 1526-6028
    ISSN (online) 1545-1550
    ISSN 1526-6028
    DOI 10.1177/15266028231173311
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Niereninfarkt seltener Ursache bei einem 28-jährigen Patienten.

    Papazoglou, Dimitrios David / Weiss, Salome / Kissling, Pascal

    Der Internist

    2021  Volume 63, Issue 2, Page(s) 221–223

    Abstract: This article presents the case of a 28-year-old male patient with a renal infarction due to an embolizing traumatic postdissection aneurysm of a renal segmental artery. He presented with abdominal and flank pain 1.5 years after a motorcycle accident. The ...

    Title translation Rare cause of renal infarction in a 28-year-old male patient.
    Abstract This article presents the case of a 28-year-old male patient with a renal infarction due to an embolizing traumatic postdissection aneurysm of a renal segmental artery. He presented with abdominal and flank pain 1.5 years after a motorcycle accident. The C‑reactive protein (CRP) and lactate dehydrogenase (LDH) levels were elevated and the diagnosis was made by computed tomography (CT) angiography. Other causes of renal infarction were excluded. After an interdisciplinary discussion we decided to use interventional coiling in this young and athletically active patient in order to avoid long-term anticoagulation.
    MeSH term(s) Adult ; Aneurysm, Dissecting/diagnostic imaging ; Humans ; Infarction/diagnosis ; Infarction/etiology ; Kidney ; Kidney Diseases ; Male ; Renal Artery/diagnostic imaging ; Tomography, X-Ray Computed
    Language German
    Publishing date 2021-10-15
    Publishing country Germany
    Document type Case Reports ; Journal Article
    ZDB-ID 2913-0
    ISSN 1432-1289 ; 0020-9554
    ISSN (online) 1432-1289
    ISSN 0020-9554
    DOI 10.1007/s00108-021-01186-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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