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  1. Article ; Online: Thermoplastic clear dental aligners under cyclic compression loading: A mechanical performance analysis using acoustic emission technique.

    Barile, Claudia / Cianci, Claudia / Paramsamy Kannan, Vimalathithan / Pappalettera, Giovanni / Pappalettere, Carmine / Casavola, Caterina / Suriano, Carmela / Ciavarella, Domenico

    Journal of the mechanical behavior of biomedical materials

    2024  Volume 152, Page(s) 106451

    Abstract: The objective of this work is to analyse the performance of clear aligners made of thermoplastic materials. Within this framework, the damage evolution stages and damage states of the aligners at different cycles of the compressive loading are evaluated ... ...

    Abstract The objective of this work is to analyse the performance of clear aligners made of thermoplastic materials. Within this framework, the damage evolution stages and damage states of the aligners at different cycles of the compressive loading are evaluated using the Acoustic Emission (AE) technique. Three different clear aligner systems were prepared: thermoformed PET-g (polyethylene terephthalate glycol) and PU (polyurethane), and additively manufactured PU. Cyclic compression tests are performed to simulate 22500 swallows. The mechanical results show that the energy absorbed by the thermoformed PET-g aligner remains stable around 4 Nmm throughout the test. Although the PU-based aligners show a higher energy absorption of about 7 Nmm during the initial phase of the cyclic loading, this gradually decreases after 12500 cycles. The time-domain based, and frequency-based parameters of the stress wave acoustic signals generated by the aligners under compression loading are used to identify the damage evolution stages. The machine learning-based AE results reveal the initiation and termination of the different damage states in the aligners and the frequency-based results distinguish the different damage sources. Finally, the microscopy results validated the damage occurrences in the aligners identified by the AE results. The mechanical test results indicate that the thermoformed PET-g has the potential to match the performance and requirements of the dentistry of the popular Invisalign (additively manufactured PU). The AE results have the potential to identify at which cycles the aligners may start losing their functionality.
    MeSH term(s) Physical Phenomena ; Acoustics ; Microscopy ; Orthodontic Appliances, Removable ; Polyurethanes
    Chemical Substances Polyurethanes
    Language English
    Publishing date 2024-02-01
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2378381-3
    ISSN 1878-0180 ; 1751-6161
    ISSN (online) 1878-0180
    ISSN 1751-6161
    DOI 10.1016/j.jmbbm.2024.106451
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A full-field DIC analysis of the mechanical-deformation behavior of polyethylene terephthalate glycol (PET-G) aligners.

    Casavola, Caterina / Pappalettera, Giovanni / Pappalettere, Carmine / Patronelli, Marika / Renna, Gilda / Laurenziello, Michele / Ciavarella, Domenico

    Journal of the mechanical behavior of biomedical materials

    2022  Volume 134, Page(s) 105391

    Abstract: Objectives: The aim was to investigate the full-field mechanical-deformation behavior of clear aligners made by polyethylene terephthalate glycol (PET-G) subjected to cyclic compression tests.: Methods: Digital Image Correlation (DIC) (Chu et al., ... ...

    Abstract Objectives: The aim was to investigate the full-field mechanical-deformation behavior of clear aligners made by polyethylene terephthalate glycol (PET-G) subjected to cyclic compression tests.
    Methods: Digital Image Correlation (DIC) (Chu et al., 1985; Schreier et al., 2009), a contactless full-field measurement technique, and Optical Microscope (OM) analysis were applied to study two PET-G aligners thermoformed from discs of a thickness of 0.75 mm and 0.88 mm. The clear aligners were placed on dental shape resin casts and were subjected to cyclic compression up to 13000 load cycles from 0 to 50 N at room temperature. The chosen number of load cycles simulates the average load history to which an aligner is subjected for one week. Local displacements and strains were measured for each test at 2, 6, 10, 20, 1000, 5000 and 13000 loading cycles.
    Results: Both aligners showed greater displacements in the early stages of loading, more pronounced for the 0.88 mm one. Local displacement and strain maps are derived both along the load direction and to the transverse one (never done from other researchers). Load-displacement cyclic curves allowed to evaluate the evolution of the stored energy and the stiffness during the test. The OM analyses showed significant morphological variations on the aligners' surface, such as wear and tear, high depressions and cracks, especially for the 0.75 mm specimen.
    Significance: Full-field analysis allowed to understand the mechanical behavior of device with complex geometry and complex load distribution, like invisible aligners. The knowledge of the stiffness and the direction of the total displacement helps the orthodontist to implement the best strategy to improve the patient's comfort and the treatment time.
    MeSH term(s) Humans ; Orthodontic Appliance Design ; Polyethylene Glycols ; Polyethylene Terephthalates
    Chemical Substances Polyethylene Terephthalates ; polyethylene terephthalate glycol ; Polyethylene Glycols (3WJQ0SDW1A)
    Language English
    Publishing date 2022-07-21
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2378381-3
    ISSN 1878-0180 ; 1751-6161
    ISSN (online) 1878-0180
    ISSN 1751-6161
    DOI 10.1016/j.jmbbm.2022.105391
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: In Vitro

    De Leonardis, Francesco / Barile, Simona Nicole / Cianci, Claudia / Pisano, Isabella / Merla, Giuseppe / Pappalettera, Giovanni / Casavola, Caterina / Pappalettere, Carmine

    Journal of Cancer

    2023  Volume 14, Issue 7, Page(s) 1088–1106

    Abstract: The study of the biological effects of low-energy ultrasound and its applications is a rapidly expanding research area. Low-energy ultrasound could be used as anti-tumoral therapy with or without the pharmacological combination even if the second ... ...

    Abstract The study of the biological effects of low-energy ultrasound and its applications is a rapidly expanding research area. Low-energy ultrasound could be used as anti-tumoral therapy with or without the pharmacological combination even if the second situation has been scarcely investigated up to now. Very little information is available about the ultrasound effects on healthy red blood cells, CD3, and mainly CD8 subset lymphocytes which is the main subset cell having cytotoxic function towards cancer cells. In this study, we investigated
    Language English
    Publishing date 2023-04-24
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2573318-7
    ISSN 1837-9664
    ISSN 1837-9664
    DOI 10.7150/jca.83050
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book ; Conference proceedings: Advances in experimental mechanics

    Pappalettere, Carmine

    : proceedings of the 12th International Conference on Experimental Mechanics, Bari, Italy, 29 August - 2 September 2004

    2004  

    Title variant ICEM 12
    Institution European Association for Experimental Mechanics
    Event/congress ICEM (12, 2004.08.29-09.02, Bari) ; International Conference on Experimental Mechanics (12, 2004.08.29-09.02, Bari)
    Author's details [EURASEM, European Association for Experimental Mechanics]. Ed. by Carmine Pappalettere
    Language English
    Size XLV, 808 S
    Publisher McGraw-Hill
    Publishing place Milano u.a.
    Document type Book ; Conference proceedings
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  5. Book ; Conference proceedings ; Audio / Video: Advances in experimental mechanics

    Pappalettere, Carmine

    : proceedings of the 12th International Conference on Experimental Mechanics, Bari, Italy, 29 August - 2 September 2004

    2004  

    Title variant ICEM 12
    Institution European Association for Experimental Mechanics
    Event/congress ICEM (12, 2004.08.29-09.02, Bari) ; International Conference on Experimental Mechanics (12, 2004.08.29-09.02, Bari)
    Author's details [EURASEM, European Association for Experimental Mechanics]. Ed. by Carmine Pappalettere
    Language English
    Size 1 CD-ROM
    Publisher McGraw-Hill
    Publishing place Milano u.a.
    Document type Book ; Conference proceedings ; Audio / Video
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  6. Book ; Conference proceedings: Advances in experimental mechanics

    Pappalettere, Carmine

    proceedings of the 12th International Conference on Experimental Mechanics, Bari, Italy, 29 August - 2 September 2004

    2004  

    Title variant ICEM 12
    Institution European Association for Experimental Mechanics
    Event/congress ICEM (12, 2004.08.29-09.02, Bari) ; International Conference on Experimental Mechanics (12, 2004.08.29-09.02, Bari)
    Author's details [EURASEM, European Association for Experimental Mechanics]. Ed. by Carmine Pappalettere
    Language English
    Size Medienkombination
    Publisher McGraw-Hill
    Publishing place Milano u.a.
    Document type Book ; Conference proceedings
    ISBN 8838662738 ; 9788838662737
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  7. Article ; Online: Study of cellular response induced by low intensity ultrasound frequency sweep pattern on myelomonocytic lymphoma U937 cells.

    Ivone, Mariantonietta / Pappalettere, Carmine / Watanabe, Akiko / Tachibana, Katsuro

    Journal of ultrasound

    2016  Volume 19, Issue 3, Page(s) 167–174

    Abstract: Purpose: This study will analyze the mechanical effects (immediate lysis) and biological effects (cell survival, apoptosis, cell cycle) on U937 cells subjected to different sonication conditions with increasing and decreasing frequencies and burst rate ( ...

    Abstract Purpose: This study will analyze the mechanical effects (immediate lysis) and biological effects (cell survival, apoptosis, cell cycle) on U937 cells subjected to different sonication conditions with increasing and decreasing frequencies and burst rate (number of burst of a repeating signal in a specific time unit), in order to determine the best conditions of sonication to produce high mortality, apoptosis and inhibition of hyperproliferation.
    Method: Cells are been stressed by pulse wave ultrasounds with increasing and decreasing frequencies between 400 and 620 kHz, at burst rates of 0.5, 10, 50 Hz and 50 % duty cycle (percentage of one period in which a signal is active), ultrasound intensities (spatial average-temporal peak) 0.045 and 0.09 W/cm(2). The sonication durations were 90 and 180 s.
    Results: The decreasing mode was found to be better than the increasing mode for 10 and 50 Hz burst rates, while at 0.5 Hz the increasing mode gave better results for the time of 180 s. For 10 Hz burst rate, decreasing frequency, 180 s, 0.09 W/cm(2), 20 % survival rate was found; after 6-h incubation, cells showed 13 % of early apoptosis and 11 % of late apoptosis. For these conditions of sonication, the hyperproliferation of cells was inhibited.
    Conclusion: Survival rate decreases for increasing intensity and duration with each burst rate. The best performance is decreasing mode in a range between 620 and 400 kHz, duty cycle 50 %, burst rate 10 Hz. In these conditions after 180 s duration, the average survival rate is 20 %, the survived cells manifest apoptosis after 6-h incubation and hyperproliferation is prevented. The results seem to lead toward a non-invasive and effective purging of leukemic cells.
    MeSH term(s) Apoptosis ; Cell Survival ; Humans ; Lymphoma/pathology ; Lymphoma/physiopathology ; Lymphoma/therapy ; U937 Cells ; Ultrasonic Therapy/methods
    Language English
    Publishing date 2016-09
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2365426-0
    ISSN 1876-7931 ; 1971-3495
    ISSN (online) 1876-7931
    ISSN 1971-3495
    DOI 10.1007/s40477-016-0199-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Remarks on residual stress measurement by hole-drilling and electronic speckle pattern interferometry.

    Barile, Claudia / Casavola, Caterina / Pappalettera, Giovanni / Pappalettere, Carmine

    TheScientificWorldJournal

    2014  Volume 2014, Page(s) 487149

    Abstract: Hole drilling is the most widespread method for measuring residual stress. It is based on the principle that drilling a hole in the material causes a local stress relaxation; the initial residual stress can be calculated by measuring strain in ... ...

    Abstract Hole drilling is the most widespread method for measuring residual stress. It is based on the principle that drilling a hole in the material causes a local stress relaxation; the initial residual stress can be calculated by measuring strain in correspondence with each drill depth. Recently optical techniques were introduced to measure strain; in this case, the accuracy of the final results depends, among other factors, on the proper choice of the area of analysis. Deformations are in fact analyzed within an annulus determined by two parameters: the internal and the external radius. In this paper, the influence of the choice of the area of analysis was analysed. A known stress field was introduced on a Ti grade 5 sample and then the stress was measured in correspondence with different values of the internal and the external radius of analysis; results were finally compared with the expected theoretical value.
    MeSH term(s) Algorithms ; Electronics/instrumentation ; Electronics/methods ; Interferometry/instrumentation ; Interferometry/methods ; Models, Theoretical ; Reproducibility of Results ; Stress, Mechanical
    Language English
    Publishing date 2014-07-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2075968-X
    ISSN 1537-744X ; 1537-744X
    ISSN (online) 1537-744X
    ISSN 1537-744X
    DOI 10.1155/2014/487149
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Experimental Study of the Pressures and Points of Application of the Forces Exerted between Aligner and Tooth.

    Cervinara, Francesca / Cianci, Claudia / De Cillis, Francesco / Pappalettera, Giovanni / Pappalettere, Carmine / Siciliani, Giuseppe / Lombardo, Luca

    Nanomaterials (Basel, Switzerland)

    2019  Volume 9, Issue 7

    Abstract: The analysis of forces, moments and pressure points has long been of great interest in orthodontics. Hence, we set out to define a method for measuring the pressure exerted by aligners on the teeth, and specifically to identify the precise points of ... ...

    Abstract The analysis of forces, moments and pressure points has long been of great interest in orthodontics. Hence, we set out to define a method for measuring the pressure exerted by aligners on the teeth, and specifically to identify the precise points of pressure exertion. Intraoral scans were performed on a patient with optimal alignment and levelling before and after 2º vestibularisation of the upper central incisor. Pressure sensor film was placed in a dedicated housing between the aligner and teeth in order to record the pressure exerted after 15 s of aligner application. The images captured by the film were scanned, digitised, and subsequently analysed. Areas and amounts of pressure generated by the aligners were evaluated, and the net force of each was calculated, adjusted to take into consideration passive values. The method revealed the areas of contact by which the aligner transmits force on the teeth, and the pressures at which it does so. The pressure exerted by an aligner is not evenly distributed across the entire surface of the tooth during lingual tipping of an upper incisor. The areas of force concentration were not identical, as these are influenced by factors resulting from the manufacturing and casting processes.
    Language English
    Publishing date 2019-07-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano9071010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Structural Response of Polyethylene Foam-Based Sandwich Panels Subjected to Edgewise Compression.

    Boccaccio, Antonio / Casavola, Caterina / Lamberti, Luciano / Pappalettere, Carmine

    Materials (Basel, Switzerland)

    2013  Volume 6, Issue 10, Page(s) 4545–4564

    Abstract: This study analyzes the mechanical behavior of low density polyethylene foam core sandwich panels subjected to edgewise compression. In order to monitor panel response to buckling, strains generated in the facesheets and overall out-of-plane deformations ...

    Abstract This study analyzes the mechanical behavior of low density polyethylene foam core sandwich panels subjected to edgewise compression. In order to monitor panel response to buckling, strains generated in the facesheets and overall out-of-plane deformations are measured with strain gages and projection moiré, respectively. A finite element (FE) model simulating the experimental test is developed. Numerical results are compared with moiré measurements. After having been validated against experimental evidence, the FE model is parameterized, and a trade study is carried out to investigate to what extent the structural response of the panel depends on the sandwich wall construction and facesheet/core interface defects. The projection moiré set-up utilized in this research is able to capture the sudden and very localized buckling phenomena occurring under edgewise compression of foam-based sandwich panels. Results of parametric FE analyses indicate that, if the total thickness of the sandwich wall is fixed, including thicker facesheets in the laminate yields a larger deflection of the panel that becomes more sensitive to buckling. Furthermore, the mechanical response of the foam sandwich panel is found to be rather insensitive to the level of waviness of core-facesheet interfaces.
    Language English
    Publishing date 2013-10-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma6104545
    Database MEDical Literature Analysis and Retrieval System OnLINE

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