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  1. Article ; Online: Modulation of Beta-Amyloid-Activated Primary Human Neutrophils by Dietary Phenols from Virgin Olive Oil.

    Rivero-Pino, Fernando / Grao-Cruces, Elena / Lopez-Enriquez, Soledad / Alba, Gonzalo / Marquez-Paradas, Elvira / Claro-Cala, Carmen M / Santa-Maria, Consuelo / Montserrat-de la Paz, Sergio

    Nutrients

    2023  Volume 15, Issue 4

    Abstract: The defense mechanism against harmful stimuli is inflammation. Indeed, neurodegenerative disorders can arise as a result of a persistent neuroinflammation. Beta-amyloid ( ... ...

    Abstract The defense mechanism against harmful stimuli is inflammation. Indeed, neurodegenerative disorders can arise as a result of a persistent neuroinflammation. Beta-amyloid (Aβ
    MeSH term(s) Humans ; Olive Oil/pharmacology ; Phenols/pharmacology ; Neutrophils ; Amyloid beta-Peptides ; Diet
    Chemical Substances Olive Oil ; Phenols ; Amyloid beta-Peptides
    Language English
    Publishing date 2023-02-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu15040941
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Kiwicha (

    Martinez-Lopez, Alicia / Rivero-Pino, Fernando / Villanueva, Alvaro / Toscano, Rocio / Grao-Cruces, Elena / Marquez-Paradas, Elvira / Martin, Maria E / Montserrat-de la Paz, Sergio / Millan-Linares, Maria C

    Food & function

    2022  Volume 13, Issue 22, Page(s) 11604–11614

    Abstract: The increase in the world population along with new policies aimed at a more sustainable world has led to the need of searching for new food sources, which are environmentally friendly, implying healthy and nutritious diets. This study explored the ... ...

    Abstract The increase in the world population along with new policies aimed at a more sustainable world has led to the need of searching for new food sources, which are environmentally friendly, implying healthy and nutritious diets. This study explored the biological activity of two kiwicha (
    MeSH term(s) Humans ; Inflammasomes/metabolism ; Amaranthus/chemistry ; Protein Hydrolysates/pharmacology ; NLR Family, Pyrin Domain-Containing 3 Protein/genetics ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Caco-2 Cells ; Anti-Inflammatory Agents/pharmacology ; Cytokines/metabolism ; Inflammation/drug therapy ; Inflammation/metabolism
    Chemical Substances Inflammasomes ; Protein Hydrolysates ; NLR Family, Pyrin Domain-Containing 3 Protein ; Anti-Inflammatory Agents ; Cytokines
    Language English
    Publishing date 2022-11-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 2612033-1
    ISSN 2042-650X ; 2042-6496
    ISSN (online) 2042-650X
    ISSN 2042-6496
    DOI 10.1039/d2fo02177c
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Proteomic analysis of postprandial high-density lipoproteins in healthy subjects.

    Grao-Cruces, Elena / Santos-Mejias, Alejandro / Ortea, Ignacio / Marquez-Paradas, Elvira / Martin, Maria E / Barrientos-Trigo, Sergio / Bermudez, Beatriz / Montserrat-de la Paz, Sergio

    International journal of biological macromolecules

    2022  

    Abstract: The relationship between the functionality and composition of high-density lipoproteins (HDL) is yet not fully studied, and little is known about the influence of the diet in HDL proteome. Therefore, the aim of this research was to elucidate the HDL ... ...

    Abstract The relationship between the functionality and composition of high-density lipoproteins (HDL) is yet not fully studied, and little is known about the influence of the diet in HDL proteome. Therefore, the aim of this research was to elucidate the HDL proteome associated to postprandial hyperlipidemia. Male volunteers were recruited for an interventional study with high fatty acid-based meals. Blood samples were collected before the intake (baseline), and 2-3 (postprandial peak) and 5-6 (postprandial post peak) hours later. HDL were purified and the protein composition was quantified by LC-MS/MS. Statistical analysis was performed by lineal models (amica) and by ANOVA and multi-t-test of the different conditions (MetaboAnalyst). Additionally, a clustering of the expression profiles of each protein was done with coseq R package (RStudio). Initially, 320 proteins were identified but only 119 remained after the filtering. APOM, APOE, APOB, and APOA2, proteins previously identified in the HDL proteome, were the only proteins with a statistically significant altered expression in postprandial hyperlipidemia when compared to baseline (p values <0.05 and logFC >1). In conclusion, we have been able to describe several behaviors of the whole HDL proteome during the postprandial hyperlipidemic metabolism.
    Language English
    Publishing date 2022-11-24
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2022.11.187
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book: La del molino

    Paradas, Enrique / Jiménez, Joaquín

    (La novela teatral ; Año 9 = Nr 375)

    1924  

    Author's details orig. de Enrique Paradas y Joaquín Jiménez
    Series title La novela teatral ; Año 9 = Nr 375
    Language Spanish
    Size 1 Mikrocard
    Publisher Prensa popular
    Publishing place Madrid
    Document type Book
    Database Former special subject collection: coastal and deep sea fishing

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  5. Book: La copa del olvido

    Paradas, Enrique / Jiménez, Joaquín

    (La novela teatral ; [Año 9 = Nr 372])

    1924  

    Author's details orig. Enrique Paradas y Joaquín Jiménez
    Series title La novela teatral ; [Año 9 = Nr 372]
    Language Spanish
    Size 1 Mikrocard
    Publisher Prensa popular
    Publishing place Madrid
    Document type Book
    Database Former special subject collection: coastal and deep sea fishing

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  6. Book: La copa del olvido

    Paradas, Enrique / Jiménez, Joaquín

    1923  

    Author's details orig. Enrique Paradas y Joaquín Jiménez
    Language Spanish
    Size 1 Mikrocard
    Publishing place Madrid
    Document type Book
    Database Former special subject collection: coastal and deep sea fishing

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  7. Book: La clave de sol

    Paradas, Enrique / Jiménez, Joaquín

    (La novela teatral ; Año 7 = Nr. 299)

    1922  

    Author's details orig. de Enrique Paradas y Joaquín Jiménez
    Series title La novela teatral ; Año 7 = Nr. 299
    Language Spanish
    Size 1 Mikrocard
    Publisher Prensa popular
    Publishing place Madrid
    Document type Book
    Database Former special subject collection: coastal and deep sea fishing

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  8. Book: Los pollos bien

    Paradas, Enrique / Jiménez, Joaquín

    (La novela teatral ; [Año 7 = Nr 293])

    1922  

    Author's details orig. de Enrique Paradas y Joaquín Jiménez
    Series title La novela teatral ; [Año 7 = Nr 293]
    Language Spanish
    Size 1 Mikrocard
    Publisher Prensa popular
    Publishing place Madrid
    Document type Book
    Database Former special subject collection: coastal and deep sea fishing

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  9. Book: Chiribitas

    Paradas, Enrique / Jiménez, Joaquín

    (La novela teatral ; Año 7 = Nr. 294)

    1922  

    Author's details orig. de Enrique Paradas y Joaquín Jiménez
    Series title La novela teatral ; Año 7 = Nr. 294
    Language Spanish
    Size 1 Mikrocard
    Publisher Prensa popular
    Publishing place Madrid
    Document type Book
    Database Former special subject collection: coastal and deep sea fishing

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  10. Book: El corto de genio

    Paradas, Enrique / Jiménez, Joaquín

    (La novela teatral ; [Año 7 = Nr 301])

    1922  

    Author's details orig. Enrique Paradas y Joaquín Jiménez
    Series title La novela teatral ; [Año 7 = Nr 301]
    Language Spanish
    Size 1 Mikrocard
    Publisher Prensa popular
    Publishing place Madrid
    Document type Book
    Database Former special subject collection: coastal and deep sea fishing

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