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  1. Article ; Online: Multimodality imaging in pericardial diseases.

    Chetrit, Michael / Parent, Martine / Klein, Allan L

    Panminerva medica

    2021  Volume 63, Issue 3, Page(s) 301–313

    Abstract: With a rapidly growing spectrum, non-specific symptoms and overlapping etiologies, pericardial diseases can represent a real diagnostic challenge. Consequently, multimodality imaging has taken a front seat in the diagnosis and management of these ... ...

    Abstract With a rapidly growing spectrum, non-specific symptoms and overlapping etiologies, pericardial diseases can represent a real diagnostic challenge. Consequently, multimodality imaging has taken a front seat in the diagnosis and management of these conditions. Cardiac CT offers an excellent anatomical characterization of pericardial thickening, fat stranding and/or presence of calcifications. and is also the preferred modality to assess extra-cardiac structures. Active pericardial inflammation, edema and fibrosis comprise pericardial characterization using CMR and allows for a precise diagnosis, disease staging and patient specific tailoring of therapies. PET scan still occupies a very modest role in the evaluation of pericardial diseases but might help discriminating malignant pericardial effusion and extrapulmonary tuberculous. More than ever, clinicians need to master how these modalities complement each other while avoiding unnecessary cost and to translate this knowledge into a more customized patient's care approach. The aim of this review was to recognize the role of multimodality imaging in the investigation of various pericardial diseases, assess how these modalities can impact the clinical course and treatment of these affections and finally elucidate their role in the patient's prognostication.
    MeSH term(s) Humans ; Pericardial Effusion/diagnostic imaging ; Pericardial Effusion/therapy ; Tomography, X-Ray Computed
    Language English
    Publishing date 2021-02-23
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 123572-2
    ISSN 1827-1898 ; 0031-0808
    ISSN (online) 1827-1898
    ISSN 0031-0808
    DOI 10.23736/S0031-0808.21.04270-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Recurrent acute coronary syndrome caused by a primary aortic valve sarcoma: grand rounds and literature review.

    Parent, Martine / Lachapelle, Kevin / Issa-Chergui, Badia / Alcindor, Thierry / Genest, Jacques / Mousavi, Negareh

    European heart journal. Case reports

    2022  Volume 6, Issue 11, Page(s) ytac412

    Abstract: Background: Malignant tumours of the aortic valve apparatus are extremely rare and difficult to diagnose. Their proximity to the coronary ostium may cause an acute coronary syndrome (ACS) either by infiltration or by embolization.: Case summary: We ... ...

    Abstract Background: Malignant tumours of the aortic valve apparatus are extremely rare and difficult to diagnose. Their proximity to the coronary ostium may cause an acute coronary syndrome (ACS) either by infiltration or by embolization.
    Case summary: We report a case of primary aortic valve undifferentiated sarcoma causing recurrent episodes of ACS, and we provide a literature review for primary cardiac valve tumours. This case also highlights the need for further evaluation of other causes of ACS in patients with minimal coronary artery disease risk factors and recurrent ACS.
    Conclusions: The majority of valve tumours are fibroelastomas. Sarcomas are rare and lead to poor outcomes.
    Language English
    Publishing date 2022-10-14
    Publishing country England
    Document type Case Reports
    ISSN 2514-2119
    ISSN (online) 2514-2119
    DOI 10.1093/ehjcr/ytac412
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  3. Article ; Online: Automated and semi-automated 3D echocardiographic software for aortic annulus sizing in transcatheter aortic valve implantation helps bridge the gap between expert and novice operators.

    Massie, Charles / Parent, Martine / Berthelot-Richer, Maxime / Kouz, Rémi / Palisaitis, Donald / Le, Viet / Poulin, Frédéric

    The international journal of cardiovascular imaging

    2023  Volume 39, Issue 9, Page(s) 1707–1717

    Abstract: 3D-transesophageal echocardiography (3D-TEE) is an alternative to multidetector row computed tomography (MDCT) for aortic annulus (AoA) sizing in preparation for Transcatheter aortic valve implantation (TAVI). We aim to evaluate how the fully automated ( ... ...

    Abstract 3D-transesophageal echocardiography (3D-TEE) is an alternative to multidetector row computed tomography (MDCT) for aortic annulus (AoA) sizing in preparation for Transcatheter aortic valve implantation (TAVI). We aim to evaluate how the fully automated (auto) and semi-automated (SA) TEE methods perform compared to conventional manual TEE method and the gold standard MDCT for annulus sizing both in expert and novice operators. In this prospective cohort study, eighty-nine patients with severe aortic stenosis underwent multimodality imaging with 3D-TEE and MDCT. Annular measurements were collected by expert echocardiographers using 3D auto, SA and manual methods and compared to MDCT. A novice in the field of echocardiography retrospectively measured the AoA for all patients using the same methods. TEE measurements, independently of the method used, had good to very good agreement to MDCT. They significantly underestimated aortic annular area and circumference vs. MDCT with the auto method underestimating it the most and the manual method the least (6.5% and 1.3% respectively for area and circumference). For experts, the manual TEE method offered the least systematic bias while the SA method had narrower limits of agreement (LOA). For the novice operator, SA method provided the least bias and narrower LOA vs. MDCT. There is good agreement between novice and experts for all 3 TEE methods but better agreement with auto and SA methods as opposed to manual one. Our study supports the use of 3D-TEE as a complementary method to MDCT for aortic annular sizing. The newer auto and SA software, that requires minimal operator intervention, is an easy to use, reliable and reproducible tool for aortic annulus sizing for experienced operators, and especially less experienced ones.
    MeSH term(s) Humans ; Transcatheter Aortic Valve Replacement/adverse effects ; Aortic Valve/diagnostic imaging ; Aortic Valve/surgery ; Aortic Valve Stenosis/diagnostic imaging ; Aortic Valve Stenosis/surgery ; Retrospective Studies ; Prospective Studies ; Predictive Value of Tests ; Echocardiography, Three-Dimensional/methods ; Software ; Echocardiography, Transesophageal/methods ; Multidetector Computed Tomography/methods ; Heart Valve Prosthesis Implantation
    Language English
    Publishing date 2023-08-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2055311-0
    ISSN 1875-8312 ; 1573-0743 ; 1569-5794 ; 0167-9899
    ISSN (online) 1875-8312 ; 1573-0743
    ISSN 1569-5794 ; 0167-9899
    DOI 10.1007/s10554-023-02885-z
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    Zs.A 2104: Show issues Location:
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  4. Article ; Online: 4D Flow Cardiac MR in Primary Mitral Regurgitation.

    Gorecka, Miroslawa / Cole, Charlotte / Bissell, Malenka M / Craven, Thomas P / Chew, Pei G / Dobson, Laura E / Brown, Louise A E / Paton, Maria F / Higgins, David M / Thirunavukarasu, Sharmaine / Sharrack, Noor / Javed, Wasim / Kotha, Sindhoora / Giannoudi, Marilena / Procter, Henry / Parent, Martine / Kidambi, Ananth / Swoboda, Peter P / Plein, Sven /
    Levelt, Eylem / Garg, Pankaj / Greenwood, John P

    Journal of magnetic resonance imaging : JMRI

    2024  

    Abstract: Background: Four-dimensional-flow cardiac MR (4DF-MR) offers advantages in primary mitral regurgitation. The relationship between 4DF-MR-derived mitral regurgitant volume (MR-Rvol) and the post-operative left ventricular (LV) reverse remodeling has not ... ...

    Abstract Background: Four-dimensional-flow cardiac MR (4DF-MR) offers advantages in primary mitral regurgitation. The relationship between 4DF-MR-derived mitral regurgitant volume (MR-Rvol) and the post-operative left ventricular (LV) reverse remodeling has not yet been established.
    Purpose: To ascertain if the 4DF-MR-derived MR-Rvol correlates with the LV reverse remodeling in primary mitral regurgitation.
    Study type: Prospective, single-center, two arm, interventional vs. nonintervention observational study.
    Population: Forty-four patients (male N = 30; median age 68 [59-75]) with at least moderate primary mitral regurgitation; either awaiting mitral valve surgery (repair [MVr], replacement [MVR]) or undergoing "watchful waiting" (WW).
    Field strength/sequence: 5 T/Balanced steady-state free precession (bSSFP) sequence/Phase contrast imaging/Multishot echo-planar imaging pulse sequence (five shots).
    Assessment: Patients underwent transthoracic echocardiography (TTE), phase-contrast MR (PMRI), 4DF-MR and 6-minute walk test (6MWT) at baseline, and a follow-up PMRI and 6MWT at 6 months. MR-Rvol was quantified by PMRI, 4DF-MR, and TTE by one observer. The pre-operative MR-Rvol was correlated with the post-operative decrease in the LV end-diastolic volume index (LVEDVi).
    Statistical tests: Included Student t-test/Mann-Whitney test/Fisher's exact test, Bland-Altman plots, linear regression analysis and receiver operating characteristic curves. Statistical significance was defined as P < 0.05.
    Results: While Bland-Altman plots demonstrated similar bias between all the modalities, the limits of agreement were narrower between 4DF-MR and PMRI (bias 15; limits of agreement -36 mL to 65 mL), than between 4DF-MR and TTE (bias -8; limits of agreement -106 mL to 90 mL) and PMRI and TTE (bias -23; limits of agreement -105 mL to 59 mL). Linear regression analysis demonstrated a significant association between the MR-Rvol and the post-operative decrease in the LVEDVi, when the MR-Rvol was quantified by PMRI and 4DF-MR, but not by TTE (P = 0.73). 4DF-MR demonstrated the best diagnostic performance for reduction in the post-operative LVEDVi with the largest area under the curve (4DF-MR 0.83; vs. PMRI 0.78; and TTE 0.51; P = 0.89).
    Data conclusion: This study demonstrates the potential clinical utility of 4DF-MR in the assessment of primary mitral regurgitation.
    Evidence level: 2 TECHNICAL EFFICACY: Stage 5.
    Language English
    Publishing date 2024-02-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1146614-5
    ISSN 1522-2586 ; 1053-1807
    ISSN (online) 1522-2586
    ISSN 1053-1807
    DOI 10.1002/jmri.29284
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    Zs.A 3648: Show issues Location:
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  5. Article ; Online: Cardiac reverse remodeling in primary mitral regurgitation: mitral valve replacement vs. mitral valve repair.

    Craven, Thomas P / Chew, Pei G / Dobson, Laura E / Gorecka, Miroslawa / Parent, Martine / Brown, Louise A E / Saunderson, Christopher E D / Das, Arka / Chowdhary, Amrit / Jex, Nicholas / Higgins, David M / Dall'Armellina, Erica / Levelt, Eylem / Schlosshan, Dominik / Swoboda, Peter P / Plein, Sven / Greenwood, John P

    Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance

    2023  Volume 25, Issue 1, Page(s) 43

    Abstract: Background: When feasible, guidelines recommend mitral valve repair (MVr) over mitral valve replacement (MVR) to treat primary mitral regurgitation (MR), based upon historic outcome studies and transthoracic echocardiography (TTE) reverse remodeling ... ...

    Abstract Background: When feasible, guidelines recommend mitral valve repair (MVr) over mitral valve replacement (MVR) to treat primary mitral regurgitation (MR), based upon historic outcome studies and transthoracic echocardiography (TTE) reverse remodeling studies. Cardiovascular magnetic resonance (CMR) offers reference standard biventricular assessment with superior MR quantification compared to TTE. Using serial CMR in primary MR patients, we aimed to investigate cardiac reverse remodeling and residual MR post-MVr vs MVR with chordal preservation.
    Methods: 83 patients with ≥ moderate-severe MR on TTE were prospectively recruited. 6-min walk tests (6MWT) and CMR imaging including cine imaging, aortic/pulmonary through-plane phase contrast imaging, T1 maps and late-gadolinium-enhanced (LGE) imaging were performed at baseline and 6 months after mitral surgery or watchful waiting (control group).
    Results: 72 patients completed follow-up (Controls = 20, MVr = 30 and MVR = 22). Surgical groups demonstrated comparable baseline cardiac indices and co-morbidities. At 6-months, MVr and MVR groups demonstrated comparable improvements in 6MWT distances (+ 57 ± 54 m vs + 64 ± 76 m respectively, p = 1), reduced indexed left ventricular end-diastolic volumes (LVEDVi; - 29 ± 21 ml/m
    Conclusion: In primary MR, MVR with chordal preservation may offer comparable cardiac reverse remodeling and functional benefits at 6-months when compared to MVr. Larger, multicenter CMR studies are required, which if the findings are confirmed could impact future surgical practice.
    MeSH term(s) Humans ; Mitral Valve Insufficiency/diagnostic imaging ; Mitral Valve Insufficiency/surgery ; Mitral Valve Insufficiency/pathology ; Mitral Valve/diagnostic imaging ; Mitral Valve/surgery ; Stroke Volume ; Predictive Value of Tests ; Ventricular Function, Right ; Fibrosis
    Language English
    Publishing date 2023-07-27
    Publishing country England
    Document type Multicenter Study ; Journal Article
    ZDB-ID 1458034-2
    ISSN 1532-429X ; 1097-6647
    ISSN (online) 1532-429X
    ISSN 1097-6647
    DOI 10.1186/s12968-023-00946-9
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    Zs.A 5045: Show issues Location:
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