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  1. Article ; Online: Diffusion-weighted and gadolinium-enhanced dynamic MRI in parotid gland tumors.

    Pâris, Pauline / Fath, Léa / Schultz, Philippe / Veillon, Francis / Riehm, Sophie / Severac, François / Venkatasamy, Aïna

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

    2022  

    Abstract: Purpose: To evaluate the value of diffusion-weighted imaging and dynamic contrast-enhanced MRI for the diagnosis of parotid gland tumors.: Methods: Retrospective review of patients with surgically treated parotid tumors between January 2009 and June ... ...

    Abstract Purpose: To evaluate the value of diffusion-weighted imaging and dynamic contrast-enhanced MRI for the diagnosis of parotid gland tumors.
    Methods: Retrospective review of patients with surgically treated parotid tumors between January 2009 and June 2020, who underwent a preoperative parotid gland MRI including standard morphological sequences, diffusion-weighted echoplanar imaging with apparent diffusion coefficient measurement and T1-weighted gadolinium-enhanced dynamic MRI sequences with Fat Saturation. The lesion was classified between malignant vs benign and precisions regarding its histological type were given when possible. Imaging findings were compared with pathology results.
    Results: Inclusion of 133 patients (mean age: 53 years). Multiparametric MRI had a sensitivity of 90.3%, a specificity of 77.5%, an overall accuracy of 80.5%, a positive predictive value of 54.9% and a negative predictive value of 96.3% to differentiate benign parotid tumor from malignant ones. Specificity (85.5%) and positive predictive value (67.6%) were improved for cases, where anatomical and functional MRI characteristics were conclusive and consistent with clinical findings.
    Conclusions: Combining diffusion-weighted and gadolinium-enhanced dynamic sequences, in addition to morphological ones enables high (> 90%) sensitivity to detect malignant parotid gland tumors. It also gives the possibility to characterize pleomorphic adenomas and Warthin tumors and to avoid fine-needle aspiration in cases of typical imaging presentation and reassuring clinical findings.
    Language English
    Publishing date 2022-08-11
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1017359-6
    ISSN 1434-4726 ; 0937-4477
    ISSN (online) 1434-4726
    ISSN 0937-4477
    DOI 10.1007/s00405-022-07590-6
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  2. Article ; Online: High Prevalence of Headaches During Covid-19 Infection: A Retrospective Cohort Study.

    Poncet-Megemont, Louis / Paris, Pauline / Tronchere, Amélie / Salazard, Jean-Pascal / Pereira, Bruno / Dallel, Radhouane / Aumeran, Claire / Beytout, Jean / Jacomet, Christine / Laurichesse, Henri / Lesens, Olivier / Mrozek, Natacha / Vidal, Magali / Moisset, Xavier

    Headache

    2020  Volume 60, Issue 10, Page(s) 2578–2582

    Abstract: Objectives: To document the prevalence of new headaches in patients with Covid-19 infection and the potential association with other neuro-sensorial symptoms (anosmia and ageusia). The persistence of these symptoms 1 month after recovery was also ... ...

    Abstract Objectives: To document the prevalence of new headaches in patients with Covid-19 infection and the potential association with other neuro-sensorial symptoms (anosmia and ageusia). The persistence of these symptoms 1 month after recovery was also documented.
    Background: Headaches are a very common symptom of viral infections. Surprisingly, early Chinese studies reported a relatively low prevalence (12-15%) of headaches associated with Covid-19.
    Methods: All the patients with laboratory-confirmed or chest-CT-confirmed Covid-19 infection, diagnosed between February 27
    Results: A total of 139 consecutive patients (mean [SD] age, 48.5 [15.3] years; 87 women [62.6%]) were interviewed 1 month after disappearance of fever and dyspnea (semi-structured phone interview). Overall, 59.0% (82/139) of people with Covid-19 had mild disease, 36.7% (51/139) had severe disease, and 4.3% (6/139) had critical illness. Eighty-two (59.0%; 95% CI: 50.3 to 67.3) reported new headaches during the acute phase and 3.6% (5/139) had persistent headaches 1 month after fever and dyspnea remission. Anosmia and ageusia were also very common, occurring in 60.4% (84/139) and 58.3% (81/139) of the patients, respectively. These 2 symptoms persisted in 14.4% (20/139) and 11.5% (16/139) of Covid-19 patients 1 month after recovery. Headaches were neither clearly associated with anosmia, nor with ageusia, and were not associated with disease severity (ie, requiring hospitalization or intensive care unit).
    Conclusion: This specific study highlights the high prevalence of new headaches during Covid-19 infection in French patients. Further studies are needed to refine the characterization of patients with Covid-19-associated headaches.
    MeSH term(s) Aged ; COVID-19/complications ; Cohort Studies ; Female ; France/epidemiology ; Headache/epidemiology ; Humans ; Male ; Middle Aged ; Prevalence ; Retrospective Studies ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-08-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 410130-3
    ISSN 1526-4610 ; 0017-8748
    ISSN (online) 1526-4610
    ISSN 0017-8748
    DOI 10.1111/head.13923
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  3. Article: High Prevalence of Headaches During Covid-19 Infection: A Retrospective Cohort Study

    Poncet-Megemont, Louis / Paris, Pauline / Tronchere, Amélie / Salazard, Jean-Pascal / Pereira, Bruno / Dallel, Radhouane / Aumeran, Claire / Beytout, Jean / Jacomet, Christine / Laurichesse, Henri / Lesens, Olivier / Mrozek, Natacha / Vidal, Magali / Moisset, Xavier

    Headache

    Abstract: OBJECTIVES: To document the prevalence of new headaches in patients with Covid-19 infection and the potential association with other neuro-sensorial symptoms (anosmia and ageusia). The persistence of these symptoms 1 month after recovery was also ... ...

    Abstract OBJECTIVES: To document the prevalence of new headaches in patients with Covid-19 infection and the potential association with other neuro-sensorial symptoms (anosmia and ageusia). The persistence of these symptoms 1 month after recovery was also documented. BACKGROUND: Headaches are a very common symptom of viral infections. Surprisingly, early Chinese studies reported a relatively low prevalence (12-15%) of headaches associated with Covid-19. METHODS: All the patients with laboratory-confirmed or chest-CT-confirmed Covid-19 infection, diagnosed between February 27th and April 15th , 2020 in the dedicated laboratory of Clermont-Ferrand University Hospital were followed for 1 month after recovery. RESULTS: A total of 139 consecutive patients (mean [SD] age, 48.5 [15.3] years; 87 women [62.6%]) were interviewed 1 month after disappearance of fever and dyspnea (semi-structured phone interview). Overall, 59.0% (82/139) of people with Covid-19 had mild disease, 36.7% (51/139) had severe disease, and 4.3% (6/139) had critical illness. Eighty-two (59.0%; 95% CI: 50.3 to 67.3) reported new headaches during the acute phase and 3.6% (5/139) had persistent headaches 1 month after fever and dyspnea remission. Anosmia and ageusia were also very common, occurring in 60.4% (84/139) and 58.3% (81/139) of the patients, respectively. These 2 symptoms persisted in 14.4% (20/139) and 11.5% (16/139) of Covid-19 patients 1 month after recovery. Headaches were neither clearly associated with anosmia, nor with ageusia, and were not associated with disease severity (ie, requiring hospitalization or intensive care unit). CONCLUSION: This specific study highlights the high prevalence of new headaches during Covid-19 infection in French patients. Further studies are needed to refine the characterization of patients with Covid-19-associated headaches.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #694530
    Database COVID19

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  4. Article ; Online: High Prevalence of Headaches During Covid‐19 Infection

    Poncet‐Megemont, Louis / Paris, Pauline / Tronchere, Amélie / Salazard, Jean‐Pascal / Pereira, Bruno / Dallel, Radhouane / Aumeran, Claire / Beytout, Jean / Jacomet, Christine / Laurichesse, Henri / Lesens, Olivier / Mrozek, Natacha / Vidal, Magali / Moisset, Xavier

    Headache: The Journal of Head and Face Pain ; ISSN 0017-8748 1526-4610

    A Retrospective Cohort Study

    2020  

    Keywords Neurology ; Clinical Neurology ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    DOI 10.1111/head.13923
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Poly(N-isopropylacrylamide) microgels at the oil-water interface: interfacial properties as a function of temperature.

    Monteux, Cécile / Marlière, Claire / Paris, Pauline / Pantoustier, Nadège / Sanson, Nicolas / Perrin, Patrick

    Langmuir : the ACS journal of surfaces and colloids

    2010  Volume 26, Issue 17, Page(s) 13839–13846

    Abstract: Highly monodisperse poly(N-isopropylacrylamide), PNiPAM, microgels were prepared by the conventional radical polymerization of NiPAM in the presence of dimethylamino ethyl methacrylate (DMAEMA) monomers at various concentrations. The effect of DMAEMA on ... ...

    Abstract Highly monodisperse poly(N-isopropylacrylamide), PNiPAM, microgels were prepared by the conventional radical polymerization of NiPAM in the presence of dimethylamino ethyl methacrylate (DMAEMA) monomers at various concentrations. The effect of DMAEMA on the polymerization of PNiPAM microgels was examined at constant initiator (V50) and cross-linker (MBA) concentrations. The presence of DMAEMA in the synthesis batch allows for the preparation of PNiPAM microgels with controlled size and a narrow size distribution. The oil(dodecane)/water interfacial properties of the model PNiPAM microgels were then investigated. The pendant drop technique was used to measure the interfacial tensions as a function of temperature. Over the whole range of temperature (20-45 degrees C), the interfacial tension remains low (on the order of 17 mN/m) and goes through a minimum (12 mN/m) at a temperature of about 34 degrees C, which well matches the volume phase transition temperature (VPTT) of PNiPAM microgels. Below the VPTT, the decrease in the interfacial tension with temperature is likely to be due to the adsorption of dense layers because of the decrease of the excluded volume interactions. Above the VPTT, we suggest that the increase in the interfacial tension with temperature comes from the adsorption of loosely packed PNiPAM microgels. We also studied the effect of temperature on the stability of emulsions. Dodecane in water emulsions, which form at ambient temperature, are destabilized as the temperature exceeds the VPTT. In light of the interfacial tension results, we suggest that emulsion destabilization arises from the adsorption of aggregates above the VPTT and not from an important desorption of microgels. Aggregate adsorption would bring a sufficiently high number of dodecane molecules into contact with water to induce coalescence without changing the interfacial tension very much.
    MeSH term(s) Acrylamides/chemistry ; Acrylic Resins ; Alkanes/chemistry ; Gels/chemistry ; Methacrylates/chemistry ; Particle Size ; Polymers/chemistry ; Surface Properties ; Temperature ; Water/chemistry
    Chemical Substances Acrylamides ; Acrylic Resins ; Alkanes ; Gels ; Methacrylates ; Polymers ; Water (059QF0KO0R) ; n-dodecane (11A386X1QH) ; poly-N-isopropylacrylamide (25189-55-3) ; 2-(dimethylamino)ethyl methacrylate (O0V97PV2G1)
    Language English
    Publishing date 2010-09-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2005937-1
    ISSN 1520-5827 ; 0743-7463
    ISSN (online) 1520-5827
    ISSN 0743-7463
    DOI 10.1021/la1019982
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