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Article ; Online: Mindfulness-Oriented Recovery Enhancement reduces opioid craving, pain, and negative affect among chronic pain patients on long-term opioid therapy: An analysis of within- and between-person state effects.

Parisi, Anna / Hanley, Adam Wesley / Garland, Eric L

2022 Volume 152, Page(s) 104066

Abstract: Mindfulness-Oriented Recovery Enhancement (MORE) is an integrative treatment that simultaneously addresses chronic pain and opioid misuse. MORE has been found to produce sustained reductions in opioid craving, pain, and negative affect-key risk ... ...

Abstract	Mindfulness-Oriented Recovery Enhancement (MORE) is an integrative treatment that simultaneously addresses chronic pain and opioid misuse. MORE has been found to produce sustained reductions in opioid craving, pain, and negative affect-key risk mechanisms precipitating opioid misuse for patients on long-term opioid therapy (LTOT). However, less is known about MORE's impact on state measures of acute symptoms. We examined the impact of MORE versus a supportive psychotherapy group (SG) among chronic pain patients on LTOT. Mixed models examined session and momentary effects of MORE (n = 50) versus SG (n = 45) on state measures of craving, pain, and negative affect. Decentering, curiosity, and time spent engaging in daily mindfulness practice were examined as session effect predictors. For session effects, statistically significant medium-to-large effects of treatment group were observed in favor of MORE for craving, pain, and negative affect. Higher levels of curiosity predicted improvements in craving, whereas greater decentering and mindfulness practice were associated with improvements in negative affect. For momentary effects, a significant group by time interaction was observed for craving and pain. Findings suggest that MORE provides immediate symptom relief on therapeutic targets in daily life among chronic pain patients receiving LTOT.
MeSH term(s)	Analgesics, Opioid/therapeutic use ; Chronic Pain/drug therapy ; Craving ; Humans ; Mindfulness ; Opioid-Related Disorders/complications ; Opioid-Related Disorders/drug therapy
Chemical Substances	Analgesics, Opioid
Language	English
Publishing date	2022-02-28
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	211997-3
ISSN	1873-622X ; 0005-7967
ISSN (online)	1873-622X
ISSN	0005-7967
DOI	10.1016/j.brat.2022.104066
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Article ; Online: Growing Up and Aging with Progressive Hearing Loss.

Parisi, Anna Albrecht

Rhode Island medical journal (2013)

2015 Volume 98, Issue 11, Page(s) 14

MeSH term(s)	Aging ; Disease Progression ; Hearing Loss ; Humans
Language	English
Publishing date	2015-11-02
Publishing country	United States
Document type	Journal Article ; Personal Narratives
ZDB-ID	2707068-2
ISSN	2327-2228 ; 2327-2228
ISSN (online)	2327-2228
ISSN	2327-2228
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Article: Mindfulness-Oriented Recovery Enhancement for Addictive Behavior, Psychiatric Distress, and Chronic Pain: A Multilevel Meta-Analysis of Randomized Controlled Trials.

Parisi, Anna / Roberts, R Lynae / Hanley, Adam W / Garland, Eric L

Mindfulness

2022 Volume 13, Issue 10, Page(s) 2396–2412

Language	English
Publishing date	2022-09-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	2543424-X
ISSN	1868-8535 ; 1868-8527
ISSN (online)	1868-8535
ISSN	1868-8527
DOI	10.1007/s12671-022-01964-x
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Article ; Online: Mindfulness-Oriented Recovery Enhancement for Veterans and Military Personnel on Long-Term Opioid Therapy for Chronic Pain: A Randomized Clinical Trial.

Garland, Eric L / Nakamura, Yoshio / Bryan, Craig J / Hanley, Adam W / Parisi, Anna / Froeliger, Brett / Marchand, William R / Donaldson, Gary W

The American journal of psychiatry

2024 Volume 181, Issue 2, Page(s) 125–134

Abstract: Objective: This randomized clinical trial evaluated the efficacy of Mindfulness-Oriented Recovery Enhancement (MORE) among past and present U.S. military personnel with prescriptions for long-term opioid therapy for chronic pain.: Methods: In this ... ...

Abstract	Objective: This randomized clinical trial evaluated the efficacy of Mindfulness-Oriented Recovery Enhancement (MORE) among past and present U.S. military personnel with prescriptions for long-term opioid therapy for chronic pain. Methods: In this clinical trial, 230 past and present military personnel with prescriptions for long-term opioid therapy were randomized in a 1:1 ratio to MORE or supportive psychotherapy (initially delivered in person and then via videoconferencing after the onset of the COVID-19 pandemic). Primary outcomes were chronic pain, measured by the Brief Pain Inventory, and aberrant drug-related behaviors, measured by the Current Opioid Misuse Measure, through 8 months of follow-up. Opioid dose was a key secondary outcome. Other outcomes included psychiatric symptoms, catastrophizing, positive affect, ecological momentary assessments of opioid craving, and opioid attentional bias. Results: MORE was superior to supportive psychotherapy through the 8-month follow-up in reducing pain-related functional interference, pain severity, and opioid dose. MORE reduced daily opioid dose by 20.7%, compared with a dose reduction of 3.9% with supportive psychotherapy. Although there was no overall between-group difference in opioid misuse, the in-person MORE intervention outperformed supportive psychotherapy for reducing opioid misuse. MORE reduced anhedonia, pain catastrophizing, craving, and opioid attentional bias and increased positive affect to a greater extent than supportive psychotherapy. MORE also modulated therapeutic processes, including mindful reinterpretation of pain sensations, nonreactivity, savoring, positive attention, and reappraisal. Conclusions: Among past and present U.S. military personnel, MORE led to sustained decreases in chronic pain, opioid use, craving, and opioid cue reactivity. MORE facilitated opioid dose reduction while preserving adequate pain control and preventing mood disturbances, suggesting its utility for safe opioid tapering.
MeSH term(s)	Humans ; Analgesics, Opioid/therapeutic use ; Mindfulness ; Veterans ; Military Personnel ; Chronic Pain/drug therapy ; Chronic Pain/psychology ; Pandemics ; Opioid-Related Disorders/drug therapy
Chemical Substances	Analgesics, Opioid
Language	English
Publishing date	2024-01-10
Publishing country	United States
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	280045-7
ISSN	1535-7228 ; 0002-953X
ISSN (online)	1535-7228
ISSN	0002-953X
DOI	10.1176/appi.ajp.20230272
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Article ; Online: Assessing the Potential Efficacy of an Intervention for Incarcerated People With Mental Illness.

Wilson, Amy Blank / Phillips, Jonathan / L Villodas, Melissa / Parisi, Anna / Dohler, Ehren / Ginley, Caroline

Psychiatric services (Washington, D.C.)

2023 Volume 74, Issue 10, Page(s) 1072–1076

Abstract: Objective: This preliminary study tested the efficacy of an evidence-based correctional intervention (Thinking for a Change) with an adapted delivery to incarcerated people with mental illness.: Methods: A small-scale randomized controlled trial (N= ... ...

Abstract	Objective: This preliminary study tested the efficacy of an evidence-based correctional intervention (Thinking for a Change) with an adapted delivery to incarcerated people with mental illness. Methods: A small-scale randomized controlled trial (N=47 men) was conducted. Outcomes were changes in aggression, number of behavioral infractions, and days in administrative segregation. Treatment targets were impulsivity, interpersonal problem-solving skills, and attitudes supportive of crime. Linear mixed-effects models were used to examine within-person and between-group differences over time, and nonparametric tests were used to examine between-group differences in criminal legal outcomes postintervention. Results: Statistically significant within-person differences were found for all treatment targets and for one study outcome (aggression). Statistically significant differences in impulsivity were found between the experimental and control groups (B=-7.10, p=0.02). Conclusions: Existing evidence-based correctional interventions can affect the lives of people with mental illness. Accelerated research in this area may benefit people with mental illness at high risk for criminal legal system involvement.
MeSH term(s)	Male ; Humans ; Mental Disorders/therapy ; Crime ; Criminals ; Aggression ; Prisoners
Language	English
Publishing date	2023-04-18
Publishing country	United States
Document type	Randomized Controlled Trial ; Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	1220173-x
ISSN	1557-9700 ; 1075-2730
ISSN (online)	1557-9700
ISSN	1075-2730
DOI	10.1176/appi.ps.20220355
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Article ; Online: Feasibility of recruiting in prisons during a randomized controlled trial with people with serious mental illness.

Phillips, Jonathan / Blank Wilson, Amy / Villodas, Melissa L / Parisi, Anna / Dohler, Ehren / Givens, Ashley

Clinical trials (London, England)

2022 Volume 20, Issue 1, Page(s) 22–30

Abstract: Background: Successful participant recruitment is vital to the feasibly of intervention research. In the behavioral and social sciences, intervention researchers face a myriad of recruitment barriers, many of which stem from working in real-world ... ...

Abstract	Background: Successful participant recruitment is vital to the feasibly of intervention research. In the behavioral and social sciences, intervention researchers face a myriad of recruitment barriers, many of which stem from working in real-world settings and among hard-to-access populations. Optimizing recruitment efforts requires being intentional about study planning and resource allocation, carefully documenting the outcomes of recruitment efforts, and developing and implementing procedures and strategies to overcome anticipated recruitment barriers. Methods: The current article presents recruitment flowcharts to illustrate (a) the multistep recruitment process and (b) the points of potential participant attrition during recruitment from a two-phase group-based intervention study conducted among individuals with serious mental illness incarcerated in a state prison system in the U.S. In addition, qualitative methods are used to examine strategies employed during the study to support recruitment efforts. Results: Despite challenges, this study was able to achieve recruitment goals. Analyses found the majority of potential participant attrition occurred prior to informed consent, highlighting the need for studies to track recruitment efforts in more detail than is currently recommended by commonly used guidelines. Strategies to optimize recruitment efforts included maximizing recruiter availability, developing a responsive communication approach, demonstrating respect for facility procedures and operations, and ensuring peak preparedness. Conclusion: Careful documentation of recruitment efforts and the early deployment of recruitment strategies is vital to the feasibility of intervention studies conducted in real-world settings with hard-to-access populations. The publication of recruitment procedures and outcomes can help future researchers anticipate recruitment challenges and inform recruitment goals, timelines, and strategies.
MeSH term(s)	Humans ; Prisons ; Feasibility Studies ; Informed Consent ; Communication ; Mental Disorders/therapy
Language	English
Publishing date	2022-10-21
Publishing country	England
Document type	Randomized Controlled Trial ; Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	2138796-5
ISSN	1740-7753 ; 1740-7745
ISSN (online)	1740-7753
ISSN	1740-7745
DOI	10.1177/17407745221130757
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Article ; Online: Emotional distress and pain catastrophizing predict cue-elicited opioid craving among chronic pain patients on long-term opioid therapy.

Parisi, Anna / Landicho, Hannah Louise / Hudak, Justin / Leknes, Siri / Froeliger, Brett / Garland, Eric L

Drug and alcohol dependence

2022 Volume 233, Page(s) 109361

Abstract: Background: Individuals who use illicit substances exhibit cue-elicited craving and autonomic cue-reactivity when exposed to cues associated with past drug use. However, little is known about this phenomenon among chronic pain patients on long-term ... ...

Abstract	Background: Individuals who use illicit substances exhibit cue-elicited craving and autonomic cue-reactivity when exposed to cues associated with past drug use. However, little is known about this phenomenon among chronic pain patients on long-term opioid therapy (LTOT). Negative cognitive-emotional reactivity in general (e.g., distress) and cognitive-emotional reactivity specific to pain (e.g., pain catastrophizing) might drive cue-reactivity independent of pain severity. Here we examined emotional distress and pain catastrophizing as predictors of cue-reactivity among a sample of chronic pain patients receiving LTOT. We also tested whether associations between distress, catastrophizing, and cue-reactivity differed as a function of opioid misuse status. Materials and methods: Patients receiving LTOT (N = 243) were classified as exhibiting aberrant behavior consistent with opioid misuse (MISUSE+, n = 145) or as using opioids as prescribed (MISUSE-, n = 97). Participants completed assessments of pain catastrophizing and emotional distress and then participated in an opioid cue-reactivity task one week later. Cue-elicited opioid craving and autonomic cue-reactivity were measured with craving ratings and high-frequency heart rate variability (HRV), respectively. Results: Distress and catastrophizing predicted cue-elicited craving and HRV, whereas pain severity did not. Misuser status moderated the relationship between emotional distress and self-reported craving, such that higher levels of distress predicted craving among the MISUSE+ group, but not among the MISUSE- group. No moderating effects were found for catastrophizing. Conclusions: Findings suggest that although opioids are prescribed for analgesia, the exacerbating influence of negative cognitive-emotional reactivity, both in general and specific to pain, on cue-elicited opioid craving extends beyond the effects of pain severity alone.
MeSH term(s)	Analgesics, Opioid/adverse effects ; Catastrophization ; Chronic Pain/psychology ; Craving/physiology ; Cues ; Humans ; Opioid-Related Disorders/psychology ; Psychological Distress
Chemical Substances	Analgesics, Opioid
Language	English
Publishing date	2022-02-24
Publishing country	Ireland
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	519918-9
ISSN	1879-0046 ; 0376-8716
ISSN (online)	1879-0046
ISSN	0376-8716
DOI	10.1016/j.drugalcdep.2022.109361
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Article ; Online: The impact of sexual victimization on substance use disorder treatment completion: A systematic review and meta-analysis.

Parisi, Anna / Jordan, Brooke / Jensen, Todd / Howard, Matthew O

Substance abuse

2020 Volume 43, Issue 1, Page(s) 131–142

Abstract: Background: ...

Abstract	Background:
MeSH term(s)	Crime Victims ; Humans ; Sexual Behavior ; Substance-Related Disorders/therapy
Language	English
Publishing date	2020-05-20
Publishing country	United States
Document type	Journal Article ; Meta-Analysis ; Systematic Review
ZDB-ID	1458030-5
ISSN	1547-0164 ; 0889-7077
ISSN (online)	1547-0164
ISSN	0889-7077
DOI	10.1080/08897077.2020.1748168
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Article ; Online: The Relationship Between a Lifetime History of Sexual Victimization and Perinatal Depression: A Systematic Review and Meta-Analysis.

Lombardi, Brooke N / Jensen, Todd M / Parisi, Anna B / Jenkins, Melissa / Bledsoe, Sarah E

Trauma, violence & abuse

2021 Volume 24, Issue 1, Page(s) 139–155

Abstract: Background: The association between a lifetime history of sexual victimization and the well-being of women during the perinatal period has received increasing attention. However, research investigating this relationship has yet to be systematically ... ...

Abstract	Background: The association between a lifetime history of sexual victimization and the well-being of women during the perinatal period has received increasing attention. However, research investigating this relationship has yet to be systematically reviewed or quantitatively synthesized. Aim: This systematic review and meta-analysis aims to calculate the pooled effect size estimate of the statistical association between a lifetime history of sexual victimization and perinatal depression (PND). Method: Four bibliographic databases were systematically searched, and reference harvesting was conducted to identify peer-reviewed articles that empirically examined associations between a lifetime history of sexual victimization and PND. A random effects model was used to ascertain an overall pooled effect size estimate in the form of an odds ratio and corresponding 95% confidence intervals (CIs). Subgroup analyses were also conducted to assess whether particular study features and sample characteristic (e.g., race and ethnicity) influenced the magnitude of effect size estimates. Results: This review included 36 studies, with 45 effect size estimates available for meta-analysis. Women with a lifetime history of sexual victimization had 51% greater odds of experiencing PND relative to women with no history of sexual victimization ( Conclusion: Findings provide compelling evidence for an association between a lifetime history of sexual victimization and PND. Future research should focus on screening practices and interventions that identify and support survivors of sexual victimization perinatally.
MeSH term(s)	Pregnancy ; Female ; Humans ; Depression ; Crime Victims ; Sexual Behavior ; Bullying ; Depressive Disorder
Language	English
Publishing date	2021-06-16
Publishing country	United States
Document type	Meta-Analysis ; Systematic Review ; Journal Article ; Review
ZDB-ID	2070884-1
ISSN	1552-8324 ; 1524-8380
ISSN (online)	1552-8324
ISSN	1524-8380
DOI	10.1177/15248380211021611
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Article ; Online: A Systematic Review of Interventions Targeting Criminogenic Risk Factors Among Persons With Serious Mental Illness.

Parisi, Anna / Wilson, Amy Blank / Villodas, Melissa / Phillips, Jon / Dohler, Ehren

Psychiatric services (Washington, D.C.)

2021 Volume 73, Issue 8, Page(s) 897–909

Abstract: Objective: Individuals with serious mental illness are overrepresented in the criminal justice system. Research has found that interventions targeting risk factors for recidivism (i.e., criminogenic risks) reduce justice involvement in the general ... ...

Abstract	Objective: Individuals with serious mental illness are overrepresented in the criminal justice system. Research has found that interventions targeting risk factors for recidivism (i.e., criminogenic risks) reduce justice involvement in the general correctional population. However, more needs to be learned regarding use of these interventions among individuals with serious mental illness. To this end, this systematic review synthesized research on interventions that target criminogenic risk factors and are delivered to justice-involved individuals with serious mental illness. Methods: A systematic search of six computerized bibliographic databases from inception to 2021 yielded 8,360 potentially relevant studies. Title and abstract screening, full-text reviews, and data extraction were performed independently, and discrepancies were resolved through discussion. To identify additional articles meeting inclusion criteria, experts in the field were contacted, and reference-harvesting techniques were used. Study quality was assessed with the Mixed Methods Appraisal Tool. Results: Twenty-one studies were identified that evaluated nine interventions delivered to justice-involved individuals with serious mental illness. All identified programs targeted criminogenic risk factors, were group based, and used cognitive-behavioral strategies. Study quality was moderate to high. Interventions were associated with improvements in recidivism, violence, and criminogenic risk factors. Conclusions: This review is the first to evaluate interventions targeting criminogenic risks among justice-involved individuals with serious mental illness. Findings suggest that outcomes associated with these interventions are promising. Given the overrepresentation of persons with serious mental illness in the criminal justice system, these findings provide an important step toward identifying services that curb justice involvement in this population.
MeSH term(s)	Criminal Law ; Humans ; Mental Disorders/therapy ; Recidivism/prevention & control ; Risk Factors
Language	English
Publishing date	2021-12-16
Publishing country	United States
Document type	Journal Article ; Review ; Systematic Review
ZDB-ID	1220173-x
ISSN	1557-9700 ; 1075-2730
ISSN (online)	1557-9700
ISSN	1075-2730
DOI	10.1176/appi.ps.202000928
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