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  1. Article ; Online: Valorization of Cabbage Waste as a Feedstock for Microbial Polyhydroxyalkanoate Production: Optimizing Hydrolysis Conditions and Polyhydroxyalkanoate Production.

    Yang, Jung Eun / Jeon, Hye Sung / Kim, Seulbi / Kim, Yeong Yeol / Kim, Jong-Cheol / Kim, Ho Myeong / Hwang, In Min / Park, Hae Woong

    Journal of agricultural and food chemistry

    2024  Volume 72, Issue 12, Page(s) 6110–6117

    Abstract: Establishing a platform for the bioconversion of waste resources into value-added compounds is critical for achieving a sustainable and eco-friendly economy. Herein, we produced polyhydroxyalkanoate via microbial fermentation using cabbage waste as a ... ...

    Abstract Establishing a platform for the bioconversion of waste resources into value-added compounds is critical for achieving a sustainable and eco-friendly economy. Herein, we produced polyhydroxyalkanoate via microbial fermentation using cabbage waste as a feedstock and metabolically engineered
    MeSH term(s) Polyhydroxyalkanoates ; Escherichia coli ; Brassica ; Hydrolysis ; 3-Hydroxybutyric Acid ; Malates
    Chemical Substances Polyhydroxyalkanoates ; malic acid (817L1N4CKP) ; 3-Hydroxybutyric Acid (TZP1275679) ; Malates
    Language English
    Publishing date 2024-02-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241619-0
    ISSN 1520-5118 ; 0021-8561
    ISSN (online) 1520-5118
    ISSN 0021-8561
    DOI 10.1021/acs.jafc.3c07057
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Novel Strain

    Moon, Yura / Heo, Sojeong / Park, Hee-Jung / Park, Hae Woong / Jeong, Do-Won

    Journal of microbiology and biotechnology

    2023  Volume 33, Issue 12, Page(s) 1625–1634

    Abstract: Leuconostoc ... ...

    Abstract Leuconostoc lactis
    MeSH term(s) Leuconostoc ; Fermentation ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/metabolism ; Bacteriocins/genetics ; Bacteriocins/pharmacology ; Bacteriocins/metabolism ; Fermented Foods/microbiology ; Republic of Korea ; Peptide Hydrolases/genetics ; Peptide Hydrolases/metabolism ; Food Microbiology
    Chemical Substances Anti-Bacterial Agents ; Bacteriocins ; Peptide Hydrolases (EC 3.4.-)
    Language English
    Publishing date 2023-09-07
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2412195-2
    ISSN 1738-8872 ; 1738-8872
    ISSN (online) 1738-8872
    ISSN 1738-8872
    DOI 10.4014/jmb.2306.06056
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Efficient Citrus (

    Kim, Ho Myeong / Jeong, Seul-Gi / Hwang, In Min / Park, Hae Woong

    ACS omega

    2021  Volume 6, Issue 51, Page(s) 35334–35341

    Abstract: Lactic acid bacteria produce various bioactive compounds widely used in human healthcare. However, studies on cryoprotective agents for the efficient storage of lactic acid bacteria after freeze-drying are still lacking. Here, we report the shelf-life ... ...

    Abstract Lactic acid bacteria produce various bioactive compounds widely used in human healthcare. However, studies on cryoprotective agents for the efficient storage of lactic acid bacteria after freeze-drying are still lacking. Here, we report the shelf-life extension effects of a highly efficient and eco-friendly cryoprotective agent and a cold adaptation method on
    Language English
    Publishing date 2021-12-15
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.1c04335
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Effect of storage conditions on the shelf-life extension of fungus-colonized substrates based on Metarhizium anisopliae using modified atmosphere packaging.

    Jeong, Seul-Gi / Kim, Ho Myeong / Kim, Junheon / Kim, Jae Su / Park, Hae Woong

    Scientific reports

    2022  Volume 12, Issue 1, Page(s) 423

    Abstract: Metarhizium anisopliae is a promising alternative to chemical pesticides against pine wilt disease caused by Bursaphelenchus xylophilus. Herein, we investigated the efficacy of modified atmosphere packaging (MAP) to prolong the shelf-life of the M. ... ...

    Abstract Metarhizium anisopliae is a promising alternative to chemical pesticides against pine wilt disease caused by Bursaphelenchus xylophilus. Herein, we investigated the efficacy of modified atmosphere packaging (MAP) to prolong the shelf-life of the M. anisopliae conidia. The effects of various conditions on its stability were also examined. M. anisopliae-inoculated millet grains were treated in a MAP system with different packaging materials (polypropylene, PP; polyethylene terephthalate, PET; ethylene vinyl alcohol, EVOH), gas compositions (high CO
    Language English
    Publishing date 2022-01-10
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-021-04232-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Supercooling Pretreatment Improves the Shelf-Life of Freeze-Dried

    Jeong, Seul-Gi / Choi, In Seong / Kim, Ho Myeong / Chang, Ji Yoon / Park, Hae Woong

    Journal of microbiology and biotechnology

    2022  Volume 32, Issue 12, Page(s) 1599–1604

    Abstract: Storage stability of freeze-dried lactic acid bacteria is a critical factor for their cost-effectiveness. Long-term storage of lactic acid bacteria enables microbial industry to reduce distribution costs. Herein, we investigated the effect of cold ... ...

    Abstract Storage stability of freeze-dried lactic acid bacteria is a critical factor for their cost-effectiveness. Long-term storage of lactic acid bacteria enables microbial industry to reduce distribution costs. Herein, we investigated the effect of cold adaptation under supercooling conditions at -5°C on the viability of
    MeSH term(s) Leuconostoc mesenteroides ; Freeze Drying/methods ; Lactobacillales ; Leuconostoc
    Language English
    Publishing date 2022-10-26
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2412195-2
    ISSN 1738-8872 ; 1738-8872
    ISSN (online) 1738-8872
    ISSN 1738-8872
    DOI 10.4014/jmb.2209.09022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Use of Vegetable Waste as a Culture Medium Ingredient Improves the Antimicrobial and Immunomodulatory Activities of

    Jeong, Seul-Gi / Kim, Ho Myeong / Lee, Moeun / Yang, Jung Eun / Park, Hae Woong

    Journal of microbiology and biotechnology

    2022  Volume 33, Issue 1, Page(s) 75–82

    Abstract: Lactic acid bacteria (LAB) isolated from kimchi (a traditional Korean dish typically made of fermented cabbage) can provide various health benefits, including anti-obesity, antioxidant, anti-inflammatory, anticancer, and antimicrobial effects. In this ... ...

    Abstract Lactic acid bacteria (LAB) isolated from kimchi (a traditional Korean dish typically made of fermented cabbage) can provide various health benefits, including anti-obesity, antioxidant, anti-inflammatory, anticancer, and antimicrobial effects. In this study, we examined the antimicrobial and immunomodulatory effects of
    MeSH term(s) Humans ; Vegetables/microbiology ; Lactobacillaceae ; Lactobacillales ; Anti-Infective Agents ; Brassica/microbiology ; Fermented Foods
    Chemical Substances Anti-Infective Agents
    Language English
    Publishing date 2022-12-02
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2412195-2
    ISSN 1738-8872 ; 1738-8872
    ISSN (online) 1738-8872
    ISSN 1738-8872
    DOI 10.4014/jmb.2210.10049
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Sonochemical application reduces monosaccharide levels and improves cryoprotective effect of Jerusalem artichoke extract on Leuconostoc mesenteroides WiKim33 during freeze-drying.

    Kim, Yeong Yeol / Kim, Ho Myeong / Jeong, Seul-Gi / Yang, Jung Eun / Kim, Seulbi / Park, Hae Woong

    Ultrasonics sonochemistry

    2023  Volume 95, Page(s) 106413

    Abstract: Lactic acid bacteria (LAB) are being used for probiotic and starter cultures to prevent global damage to microbial cells. To retain the benefits of LAB in the commercially used powdered form, highly efficient cryoprotective agents are required during the ...

    Abstract Lactic acid bacteria (LAB) are being used for probiotic and starter cultures to prevent global damage to microbial cells. To retain the benefits of LAB in the commercially used powdered form, highly efficient cryoprotective agents are required during the manufacturing process. This study suggests a novel cryoprotective agent derived from Jerusalem artichoke (JA; Helianthus tuberous L.) and describes the mechanism of cryoprotective effect improvement by sonication treatment. The cryoprotective effect of JA extract was verified by examining the viability of Leuconostoc mesenteroides WiKim33 after freeze-drying (FD). Sonication of JA extract improved the cryoprotective effect. Sonication reduced fructose and glucose contents, which increased the induction of critical damage during FD by 15.84% and 46.81%, respectively. The cryoprotective effects of JA and sonication-treated JA extracts were determined using the viable cell count of Leu. mesenteroides WiKim33. Immediately after FD and storage for 24 weeks, the viability of Leu. mesenteroides WiKim33 with JA extract was 82.8% and 76.3%, respectively, while that of the sonication-treated JA extract was 95.2% and 88.8%, respectively. Our results show that reduction in specific monosaccharides was correlated with improved cryoprotective effect. This study adopted sonication as a novel treatment for improving the cryoprotective effect and verified its efficiency.
    MeSH term(s) Cryoprotective Agents ; Helianthus/chemistry ; Leuconostoc mesenteroides ; Monosaccharides ; Lactobacillales ; Plant Extracts/pharmacology
    Chemical Substances Cryoprotective Agents ; Monosaccharides ; Plant Extracts
    Language English
    Publishing date 2023-04-19
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1208333-1
    ISSN 1873-2828 ; 1350-4177
    ISSN (online) 1873-2828
    ISSN 1350-4177
    DOI 10.1016/j.ultsonch.2023.106413
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Heterotypic stress-induced adaptive evolution enhances freeze-drying tolerance and storage stability of Leuconostoc mesenteroides WiKim33.

    Kim, Yeong Yeol / Kim, Jong-Cheol / Kim, Seulbi / Yang, Jung Eun / Kim, Ho Myeong / Park, Hae Woong

    Food research international (Ottawa, Ont.)

    2023  Volume 175, Page(s) 113731

    Abstract: Lactic acid bacteria (LAB) are currently being investigated for their potential use as probiotics and starter cultures. Researchers have developed powdering processes for the commercialization of LAB. Previous studies have focused on identifying ... ...

    Abstract Lactic acid bacteria (LAB) are currently being investigated for their potential use as probiotics and starter cultures. Researchers have developed powdering processes for the commercialization of LAB. Previous studies have focused on identifying innovative cryoprotective agents and freeze-drying (FD) techniques to enhance the stability of LAB. In this study, adaptive laboratory evolution (ALE) was employed to develop a strain with high FD tolerance and enhanced storage stability. Leuconostoc mesenteroids WiKim33 was subjected to heterotypic shock (heat and osmosis shock) to induce the desired phenotype and genotype. An FD-tolerant enhanced Leu. mesenteroides WiKim33 strain (ALE50) was obtained, which harbored a modified fatty acid composition and cell envelope characteristics. Specifically, ALE50 showed a lower unsaturated fatty acid (UFA)/saturated fatty acid (SFA) ratio and a higher cyclic fatty acid (CFA) composition. Moreover, the exopolysaccharide (EPS) thickness increased significantly by 331% compared to that of the wild type (WT). FD tolerance, which was evaluated using viability testing after FD, was enhanced by 33.4%. Overall, we demonstrated the feasibility of ALE to achieve desirable characteristics and provided insights into the mechanisms underlying increased FD tolerance.
    MeSH term(s) Leuconostoc mesenteroides/genetics ; Leuconostoc mesenteroides/metabolism ; Freeze Drying/methods ; Fatty Acids/metabolism ; Freezing ; Lactobacillales/genetics ; Lactobacillales/metabolism
    Chemical Substances Fatty Acids
    Language English
    Publishing date 2023-11-27
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 1111695-x
    ISSN 1873-7145 ; 0963-9969
    ISSN (online) 1873-7145
    ISSN 0963-9969
    DOI 10.1016/j.foodres.2023.113731
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Utilization of coffee waste as a sustainable feedstock for high-yield lactic acid production through microbial fermentation.

    Kim, Seulbi / Kim, Jong-Cheol / Kim, Yeong Yeol / Yang, Jung Eun / Lee, Hee Min / Hwang, In Min / Park, Hae Woong / Kim, Ho Myeong

    The Science of the total environment

    2023  Volume 912, Page(s) 169521

    Abstract: Lactic acid is an important industrial precursor; however, high substrate costs are a major challenge in microbial fermentation-based lactic acid production. Coffee waste is a sustainable feedstock alternative for lactic acid production via microbial ... ...

    Abstract Lactic acid is an important industrial precursor; however, high substrate costs are a major challenge in microbial fermentation-based lactic acid production. Coffee waste is a sustainable feedstock alternative for lactic acid production via microbial fermentation. Herein, the feasibility of coffee waste as a feedstock was explored by employing appropriate pretreatment methods and optimizing enzyme combinations. Coffee waste pretreatment with hydrogen peroxide and acetic acid along with a combination of Viscozyme L, Celluclast 1.5 L, and Pectinex Ultra SP-L achieved the 78.9 % sugar conversion rate at a substrate concentration of 4 % (w/v). Lactiplantibacillus plantarum WiKim0126-induced fermentation with a 4 % solid loading yielded a lactic acid concentration of 22.8 g/L (99.6 % of the theoretical maximum yield) and productivity of 0.95 g/L/h within 24 h. These findings highlight the viability of coffee waste as an eco-friendly resource for sustainable lactic acid production.
    MeSH term(s) Fermentation ; Lactic Acid ; Coffee ; Carbohydrates ; Lactobacillus plantarum
    Chemical Substances Lactic Acid (33X04XA5AT) ; Coffee ; Carbohydrates
    Language English
    Publishing date 2023-12-22
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2023.169521
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Correction to: Rapid analysis of insecticidal metabolites from the entomopathogenic fungus Beauveria bassiana 331R using UPLC-Q-Orbitrap MS.

    Kim, Jong-Cheol / Hwang, In Min / Kim, Ho Myeong / Kim, Seulbi / Shin, Teak Su / Woo, Soo-Dong / Park, Hae Woong

    Mycotoxin research

    2023  Volume 40, Issue 1, Page(s) 133

    Language English
    Publishing date 2023-12-23
    Publishing country Germany
    Document type Published Erratum
    ZDB-ID 14500-2
    ISSN 1867-1632 ; 0178-7888
    ISSN (online) 1867-1632
    ISSN 0178-7888
    DOI 10.1007/s12550-023-00516-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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