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  1. Article ; Online: Sustained Low Income, Income Changes, and Risk of All-Cause Mortality in Individuals With Type 2 Diabetes: A Nationwide Population-Based Cohort Study.

    Lee, Hong Seok / Park, Jimin Clara / Chung, Inkwan / Liu, Junxiu / Lee, Seong-Su / Han, Kyungdo

    Diabetes care

    2022  Volume 46, Issue 1, Page(s) 92–100

    Abstract: Objective: There is limited evidence on the association of sustained low-income status, income changes, and all-cause mortality risk in individuals with type 2 diabetes (T2D).: Research design and methods: Using the Korean Health Insurance Service ... ...

    Abstract Objective: There is limited evidence on the association of sustained low-income status, income changes, and all-cause mortality risk in individuals with type 2 diabetes (T2D).
    Research design and methods: Using the Korean Health Insurance Service database, we studied 1,923,854 adults with T2D (aged ≥30 years) without cardiovascular disease and cancer, who were enrolled from 2009 through 2012 and followed to the end of 2020 (median 10.8 years of follow-up). We defined income levels based on the amount of health insurance premiums and categorized them into quartiles, the first being the low-income group, and assessed the income status annually in the preceding 5 years. Cox proportional hazards models were used to quantify the association of low-income status and income changes with mortality, with adjustment for sociodemographic factors, comorbidities, and diabetes duration and treatment.
    Results: Participants who consecutively had low income showed a higher risk of mortality (hazard ratio [HR] 1.19; 95% CI 1.16-1.22), compared with those who had never been in the low-income group. This association was much stronger for consecutive recipients of Medical Aid, reflecting very-low-income status (HR 2.26; 95% CI 2.16-2.36), compared with those who had never been Medical Aid beneficiaries. Sustained low- and very-low-income status was associated with increased risk of mortality, specifically for younger adults (aged <40 years) and males. Those who experienced declines in income between the first (preceding 5 years) and the last (baseline) time points had an increased risk of mortality, regardless of baseline income status.
    Conclusions: Among Korean adults with T2D, sustained low-income status and declines in income were associated with increased risk of mortality.
    MeSH term(s) Adult ; Male ; Humans ; Diabetes Mellitus, Type 2/epidemiology ; Cohort Studies ; Income ; Socioeconomic Factors ; Poverty ; Cardiovascular Diseases ; Risk Factors
    Language English
    Publishing date 2022-11-08
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 441231-x
    ISSN 1935-5548 ; 0149-5992
    ISSN (online) 1935-5548
    ISSN 0149-5992
    DOI 10.2337/dc21-2305
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Association of Sustained Low or High Income and Income Changes With Risk of Incident Type 2 Diabetes Among Individuals Aged 30 to 64 Years.

    Park, Jimin Clara / Nam, Ga Eun / Yu, Jinna / McWhorter, Ketrell L / Liu, Junxiu / Lee, Hong Seok / Lee, Seong-Su / Han, Kyungdo

    JAMA network open

    2023  Volume 6, Issue 8, Page(s) e2330024

    Abstract: Importance: Evidence of the association between income fluctuation and risk of type 2 diabetes (T2D) is scarce.: Objective: To investigate whether sustained low or high income and income changes are associated with incidence of T2D.: Design, ... ...

    Abstract Importance: Evidence of the association between income fluctuation and risk of type 2 diabetes (T2D) is scarce.
    Objective: To investigate whether sustained low or high income and income changes are associated with incidence of T2D.
    Design, setting, and participants: In this population-based cohort study, more than 7.8 million adults without T2D aged 30 to 64 years from a nationally representative sample from the Korean Health Insurance Service database were enrolled in 2012 and followed up to 2019 (median follow-up, 6.3 years [IQR, 6.1-6.6 years]).
    Exposures: Twenty quantiles of monthly health insurance premiums determined income levels. Income quartiles were annually analyzed from 2008 to 2012. Beneficiaries of the Medical Aid Program were regarded as those with very low income. A decrease in income was indicated as a reduction of 25% or more in income compared with income in the previous year.
    Main outcomes and measures: The primary outcome was incident T2D based on the International Statistical Classification of Diseases and Related Health Problems, Tenth Revision codes E11 to E14, 1 or more claims of antidiabetic medication, or a fasting glucose level of 126 mg/dL or higher. Multivariable Cox proportional hazards models were used to assess the association of low- or high-income status and income changes with incidence of T2D.
    Results: Of 7 821 227 participants (mean [SD] age, 46.4 [9.3] years; 54.9% men), 359 931 (4.6%) developed T2D at least 1 year after enrollment. Individuals who repeatedly experienced low and very low income for 5 years showed 22% (hazard ratio [HR], 1.22 [95% CI, 1.21-1.23]) and 57% (1.57 [95% CI, 1.53-1.62]) higher T2D risk compared with those who never experienced low and very low income, respectively. In contrast, individuals who were repeatedly in high-income quartiles showed lower T2D risk compared with those who never experienced high income (HR, 0.86 [95% CI, 0.85-0.86]). The number of income decreases was associated with elevated T2D risk (≥2 vs 0 income decreases: HR, 1.08 [95% CI, 1.06-1.11]; P < .001 for trend). When income quartile status was compared between 2008 and 2012, individuals who experienced an income increase had lowered T2D risk, while those who experienced an income decrease had elevated T2D risk in each income quartile group.
    Conclusions and relevance: This cohort study found that individuals who experienced sustained low-income status or an income decrease had elevated T2D risk, while those who had sustained high-income status or an income increase had lowered T2D risk.
    MeSH term(s) Adult ; Male ; Humans ; Middle Aged ; Female ; Diabetes Mellitus, Type 2/epidemiology ; Cohort Studies ; Income ; Poverty ; Socioeconomic Factors
    Language English
    Publishing date 2023-08-01
    Publishing country United States
    Document type Journal Article
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2023.30024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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