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  1. Article: To Take or Not to Take: The Dilemma With Marginal Donor Heart?

    Park, Jin Joo

    Korean circulation journal

    2023  Volume 53, Issue 4, Page(s) 268–270

    Language English
    Publishing date 2023-05-10
    Publishing country Korea (South)
    Document type Editorial
    ZDB-ID 2557464-4
    ISSN 1738-5520
    ISSN 1738-5520
    DOI 10.4070/kcj.2023.0045
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: On-Treatment Diastolic Blood Pressure: When Is It Too High?

    Park, Jin Joo

    Korean circulation journal

    2022  Volume 52, Issue 6, Page(s) 475–477

    Language English
    Publishing date 2022-06-03
    Publishing country Korea (South)
    Document type Editorial
    ZDB-ID 2557464-4
    ISSN 1738-5520
    ISSN 1738-5520
    DOI 10.4070/kcj.2022.0126
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Epidemiology, Pathophysiology, Diagnosis and Treatment of Heart Failure in Diabetes.

    Park, Jin Joo

    Diabetes & metabolism journal

    2021  Volume 45, Issue 2, Page(s) 146–157

    Abstract: The cardiovascular disease continuum begins with risk factors such as diabetes mellitus (DM), progresses to vasculopathy and myocardial dysfunction, and finally ends with cardiovascular death. Diabetes is associated with a 2- to 4-fold increased risk for ...

    Abstract The cardiovascular disease continuum begins with risk factors such as diabetes mellitus (DM), progresses to vasculopathy and myocardial dysfunction, and finally ends with cardiovascular death. Diabetes is associated with a 2- to 4-fold increased risk for heart failure (HF). Moreover, HF patients with DM have a worse prognosis than those without DM. Diabetes can cause myocardial ischemia via micro- and macrovasculopathy and can directly exert deleterious effects on the myocardium. Hyperglycemia, hyperinsulinemia, and insulin resistance can cause alterations in vascular homeostasis. Then, reduced nitric oxide and increased reactive oxygen species levels favor inflammation leading to atherothrombotic progression and myocardial dysfunction. The classification, diagnosis, and treatment of HF for a patient with and without DM remain the same. Until now, drugs targeting neurohumoral and metabolic pathways improved mortality and morbidity in HF with reduced ejection fraction (HFrEF). Therefore, all HFrEF patients should receive guideline-directed medical therapy. By contrast, drugs modulating neurohumoral activity did not improve survival in HF with preserved ejection fraction (HFpEF) patients. Trials investigating whether sodium-glucose cotransporter-2 inhibitors are effective in HFpEF are on-going. This review will summarize the epidemiology, pathophysiology, and treatment of HF in diabetes.
    MeSH term(s) Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/diagnosis ; Diabetes Mellitus, Type 2/drug therapy ; Heart Failure/diagnosis ; Heart Failure/epidemiology ; Heart Failure/etiology ; Humans ; Myocardium ; Sodium-Glucose Transporter 2 Inhibitors ; Stroke Volume
    Chemical Substances Sodium-Glucose Transporter 2 Inhibitors
    Language English
    Publishing date 2021-03-25
    Publishing country Korea (South)
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2602402-0
    ISSN 2233-6087 ; 2233-6087
    ISSN (online) 2233-6087
    ISSN 2233-6087
    DOI 10.4093/dmj.2020.0282
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Epidemiology, Pathophysiology, Diagnosis and Treatment of Heart Failure in Diabetes.

    Park, Jin Joo

    Diabetes & metabolism journal

    2021  Volume 45, Issue 5, Page(s) 796

    Language English
    Publishing date 2021-09-30
    Publishing country Korea (South)
    Document type Published Erratum
    ZDB-ID 2602402-0
    ISSN 2233-6087 ; 2233-6087
    ISSN (online) 2233-6087
    ISSN 2233-6087
    DOI 10.4093/dmj.2021.0239
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Topping Off the Pill Box: Dapagliflozin, Heart Failure, and Polypharmacy.

    Park, Jin Joo / Greenberg, Barry

    JACC. Heart failure

    2023  Volume 11, Issue 10, Page(s) 1394–1396

    MeSH term(s) Humans ; Heart Failure/drug therapy ; Polypharmacy ; Benzhydryl Compounds/therapeutic use ; Glucosides/therapeutic use ; Stroke Volume ; Ventricular Function, Left
    Chemical Substances dapagliflozin (1ULL0QJ8UC) ; Benzhydryl Compounds ; Glucosides
    Language English
    Publishing date 2023-08-09
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2705621-1
    ISSN 2213-1787 ; 2213-1779
    ISSN (online) 2213-1787
    ISSN 2213-1779
    DOI 10.1016/j.jchf.2023.06.033
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Computed Tomography for Assessment of Left Atrial Appendage Function.

    Park, Jin Joo

    Korean circulation journal

    2018  Volume 49, Issue 2, Page(s) 181–182

    Language English
    Publishing date 2018-11-07
    Publishing country Korea (South)
    Document type Editorial
    ZDB-ID 2557464-4
    ISSN 1738-5520
    ISSN 1738-5520
    DOI 10.4070/kcj.2018.0355
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Current status of heart failure: global and Korea.

    Park, Jin Joo / Choi, Dong-Ju

    The Korean journal of internal medicine

    2020  Volume 35, Issue 3, Page(s) 487–497

    Abstract: Heart failure (HF) is a condition in which the heart is unable to pump enough blood to meet the body's needs for blood and oxygen. Thus, HF is a grave disease with high morbidity and mortality. Because the prevalence of and exposure to the risk factors ... ...

    Abstract Heart failure (HF) is a condition in which the heart is unable to pump enough blood to meet the body's needs for blood and oxygen. Thus, HF is a grave disease with high morbidity and mortality. Because the prevalence of and exposure to the risk factors for HF increase with age, the prevalence of HF has been increasing in an aging society, including Korea. The vast advancement of medical and device therapy has improved the outcomes of HF, but significant residual risk still exists, and the benefit is confined to patients with reduced ejection fraction. Finding effective treatment for HF with preserved ejection fraction and identification of groups who benefit from drug and device therapy remain challenging. In this review, we illustrate the epidemiology, temporal trends, and current status of medical and device therapy, including heart transplantation, as well as emerging treatments for HF in Korea and worldwide.
    MeSH term(s) Heart Failure/diagnosis ; Heart Failure/epidemiology ; Heart Failure/therapy ; Humans ; Republic of Korea/epidemiology ; Risk Factors ; Stroke Volume ; Ventricular Dysfunction, Left
    Language English
    Publishing date 2020-04-29
    Publishing country Korea (South)
    Document type Journal Article ; Review
    ZDB-ID 639023-7
    ISSN 2005-6648 ; 1226-3303
    ISSN (online) 2005-6648
    ISSN 1226-3303
    DOI 10.3904/kjim.2020.120
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Global longitudinal strain predicts clinical outcomes in patients with heart failure with preserved ejection fraction.

    Brann, Alison / Miller, James / Eshraghian, Emily / Park, Jin Joo / Greenberg, Barry

    European journal of heart failure

    2023  Volume 25, Issue 10, Page(s) 1755–1765

    Abstract: Aims: Patients with heart failure with preserved ejection fraction (HFpEF) are at high risk for hospitalization and mortality and many of these patients experience a deterioration in left ventricular ejection fraction (LVEF) over time. Global ... ...

    Abstract Aims: Patients with heart failure with preserved ejection fraction (HFpEF) are at high risk for hospitalization and mortality and many of these patients experience a deterioration in left ventricular ejection fraction (LVEF) over time. Global longitudinal strain (GLS) is a sensitive marker of myocardial dysfunction that could help predict risk for future events in this population. We assessed whether GLS can predict adverse clinical outcomes and future deterioration in LVEF in patients with HFpEF.
    Methods and results: In this retrospective cohort study, patients with HFpEF were divided into groups according to abnormal GLS (>-15.8%) or normal GLS (<-15.8%).The primary outcomes were: a composite of cardiovascular mortality or heart failure hospitalization and deterioration in LVEF to <40%. Among the 311 patients with HFpEF, 128 patients (41%) had normal GLS and 183 patients (59%) had abnormal GLS. After a median follow-up of 4.6 years, the composite outcome occurred more commonly in patients with abnormal GLS compared to patients with normal GLS (62% vs. 44%; hazard ratio [HR] 1.74, 95% confidence interval [CI] 1.3-2.4, p < 0.001). Patients with abnormal GLS were also more likely to experience a deterioration in LVEF (19% vs. 10%; HR 2.2, 95% CI 1.2-4.3, p = 0.018). When assessed as a continuous variable, each 1% increase in GLS was associated with 10% increased odds for the composite outcome and 13% increased odds for deterioration in LVEF.
    Conclusion: In patients with HFpEF, abnormal GLS is common and is a strong predictor for clinical events and future deterioration in LVEF.
    MeSH term(s) Humans ; Ventricular Function, Left ; Stroke Volume ; Retrospective Studies ; Heart Failure ; Global Longitudinal Strain ; Prognosis ; Ventricular Dysfunction, Left/epidemiology
    Language English
    Publishing date 2023-07-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 1483672-5
    ISSN 1879-0844 ; 1388-9842
    ISSN (online) 1879-0844
    ISSN 1388-9842
    DOI 10.1002/ejhf.2947
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Reply: Time to Diuretic in Acute Heart Failure.

    Park, Jin Joo / Choi, Dong-Ju

    JACC. Heart failure

    2018  Volume 6, Issue 8, Page(s) 723

    MeSH term(s) Diuretics ; Furosemide ; Heart Failure ; Humans ; Sodium Potassium Chloride Symporter Inhibitors
    Chemical Substances Diuretics ; Sodium Potassium Chloride Symporter Inhibitors ; Furosemide (7LXU5N7ZO5)
    Language English
    Publishing date 2018-07-30
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2705621-1
    ISSN 2213-1787 ; 2213-1779
    ISSN (online) 2213-1787
    ISSN 2213-1779
    DOI 10.1016/j.jchf.2018.06.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Reply: Finding a Balance Between Quality and Quantity of Data in Acute Heart Failure.

    Park, Jin Joo / Choi, Dong-Ju

    JACC. Heart failure

    2018  Volume 6, Issue 7, Page(s) 616

    MeSH term(s) Diuretics ; Heart Failure ; Humans
    Chemical Substances Diuretics
    Language English
    Publishing date 2018-06-28
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2705621-1
    ISSN 2213-1787 ; 2213-1779
    ISSN (online) 2213-1787
    ISSN 2213-1779
    DOI 10.1016/j.jchf.2018.04.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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