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  1. Article ; Online: Characterization of Microstructure and Properties of Additively Manufactured Materials under Room and Elevated Temperatures

    Balaji B. / Rajashekar N. / Parmar Ashish / Arora Vandana / Abdul-Zahra Dalael Saad / Nijhawan Ginni

    E3S Web of Conferences, Vol 430, p

    2023  Volume 01101

    Abstract: The utilisation of additive manufacturing (AM) has brought about a significant transformation in the manufacturing process of materials and components, since it allows for the creation of complex geometries and customised designs. The primary objective ... ...

    Abstract The utilisation of additive manufacturing (AM) has brought about a significant transformation in the manufacturing process of materials and components, since it allows for the creation of complex geometries and customised designs. The primary objective of this study is to conduct a thorough analysis of the microstructure and characteristics of materials produced by additive manufacturing techniques, including the effects of varying temperatures ranging from ambient temperature to increased levels. Microstructural analysis encompasses several methods, including optical microscopy, scanning electron microscopy (SEM), and X-ray diffraction (XRD), which are employed to investigate the grain structure, porosity, and phase composition. Standardised testing procedures are employed to assess mechanical qualities, such as tensile strength, hardness, and fracture toughness. temperature analysis methods, such as differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA), are utilised in order to examine the temperature stability and phase transitions. This study investigates the impact of various printing factors, including layer thickness, printing speed, and build orientation, on the resultant microstructure and characteristics. This study aims to address the disparity between theoretical understanding and actual implementation, therefore facilitating the wider use of additively made materials in businesses that need exceptional performance in many environments.
    Keywords Environmental sciences ; GE1-350
    Subject code 669
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  2. Article: Rhabdomyolysis and Acute Renal Dysfunction as Initial Manifestations of Monoclonal Gammopathy of Renal Significance.

    Gudapati, Prathyusha / Al-Sultani, Anmar / Parmar, Ashish / Motwani, Reena / Fortkort, Peter

    Cureus

    2023  Volume 15, Issue 2, Page(s) e34759

    Abstract: Monoclonal gammopathy of renal significance (MGRS) is a rare heterogeneous group of kidney disorders that encompasses all disorders caused by deposition of monoclonal protein (M-protein) and its light or heavy chain fragments secreted by pre-malignant or ...

    Abstract Monoclonal gammopathy of renal significance (MGRS) is a rare heterogeneous group of kidney disorders that encompasses all disorders caused by deposition of monoclonal protein (M-protein) and its light or heavy chain fragments secreted by pre-malignant or non-malignant B-cell clones in patients who do not meet the diagnostic criteria for multiple myeloma (MM) or other B-cell malignancies. MGRS can manifest as glomerular diseases, tubulopathies, or vascular involvement with varying clinical presentations, making the diagnosis of MGRS challenging. In patients with high clinical suspicion based on preliminary blood and urine studies, the evaluation of MGRS begins with a renal biopsy followed by monoclonal studies and cytogenetic analysis. There is no standard treatment protocol for MGRS, and the current consensus suggests a clone-directed approach. If not identified and treated early, MGRS often results in poor outcomes and can lead to extrarenal manifestations, such as cardiogenic shock. Herein, we present a case involving a 43-year-old male with a rare presentation of rhabdomyolysis, rapidly progressing renal dysfunction, and cardiac dysfunction. A bone marrow biopsy did not meet the diagnostic criteria for MM or other B-cell malignancies, while a renal biopsy revealed Kappa light chain cast nephropathy, which led to the final diagnosis of MGRS.
    Language English
    Publishing date 2023-02-08
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.34759
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Guggulsterone Activates Adipocyte Beiging through Direct Effects on 3T3-L1 Adipocytes and Indirect Effects Mediated through RAW264.7 Macrophages.

    Miller, Colette N / Samuels, Janaiya S / Azhar, Yusra / Parmar, Ashish / Shashidharamurthy, Rangaiah / Rayalam, Srujana

    Medicines (Basel, Switzerland)

    2019  Volume 6, Issue 1

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2019-01-31
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2777965-8
    ISSN 2305-6320
    ISSN 2305-6320
    DOI 10.3390/medicines6010022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Phytochemicals as novel agents for the induction of browning in white adipose tissue

    Azhar, Yusra / Parmar, Ashish / Miller, Colette N / Samuels, Janaiya S / Rayalam, Srujana

    Nutrition & metabolism. 2016 Dec., v. 13, no. 1

    2016  

    Abstract: Obesity and its associated metabolic syndrome continue to be a health epidemic in westernized societies and is catching up in the developing world. Despite such increases, little headway has been made to reverse adverse weight gain in the global ... ...

    Abstract Obesity and its associated metabolic syndrome continue to be a health epidemic in westernized societies and is catching up in the developing world. Despite such increases, little headway has been made to reverse adverse weight gain in the global population. Few medical options exist for the treatment of obesity which points to the necessity for exploration of anti-obesity therapies including pharmaceutical and nutraceutical compounds. Defects in brown adipose tissue, a major energy dissipating organ, has been identified in the obese and is hypothesized to contribute to the overall metabolic deficit observed in obesity. Not surprisingly, considerable attention has been placed on the discovery of methods to activate brown adipose tissue. A variety of plant-derived, natural compounds have shown promise to regulate brown adipose tissue activity and enhance the lipolytic and catabolic potential of white adipose tissue. Through activation of the sympathetic nervous system, thyroid hormone signaling, and transcriptional regulation of metabolism, natural compounds such as capsaicin and resveratrol may provide a relatively safe and effective option to upregulate energy expenditure. Through utilizing the energy dissipating potential of such nutraceutical compounds, the possibility exists to provide a therapeutic solution to correct the energy imbalance that underlines obesity.
    Keywords brown adipose tissue ; capsaicin ; energy expenditure ; functional foods ; metabolic syndrome ; metabolism ; obesity ; phytopharmaceuticals ; resveratrol ; sympathetic nervous system ; thyroid hormones ; transcription (genetics) ; white adipose tissue
    Language English
    Dates of publication 2016-12
    Size p. 89.
    Publishing place BioMed Central
    Document type Article
    Note Review
    ISSN 1743-7075
    DOI 10.1186/s12986-016-0150-6
    Database NAL-Catalogue (AGRICOLA)

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  5. Article: Phytochemicals as novel agents for the induction of browning in white adipose tissue.

    Azhar, Yusra / Parmar, Ashish / Miller, Colette N / Samuels, Janaiya S / Rayalam, Srujana

    Nutrition & metabolism

    2016  Volume 13, Page(s) 89

    Abstract: Obesity and its associated metabolic syndrome continue to be a health epidemic in westernized societies and is catching up in the developing world. Despite such increases, little headway has been made to reverse adverse weight gain in the global ... ...

    Abstract Obesity and its associated metabolic syndrome continue to be a health epidemic in westernized societies and is catching up in the developing world. Despite such increases, little headway has been made to reverse adverse weight gain in the global population. Few medical options exist for the treatment of obesity which points to the necessity for exploration of anti-obesity therapies including pharmaceutical and nutraceutical compounds. Defects in brown adipose tissue, a major energy dissipating organ, has been identified in the obese and is hypothesized to contribute to the overall metabolic deficit observed in obesity. Not surprisingly, considerable attention has been placed on the discovery of methods to activate brown adipose tissue. A variety of plant-derived, natural compounds have shown promise to regulate brown adipose tissue activity and enhance the lipolytic and catabolic potential of white adipose tissue. Through activation of the sympathetic nervous system, thyroid hormone signaling, and transcriptional regulation of metabolism, natural compounds such as capsaicin and resveratrol may provide a relatively safe and effective option to upregulate energy expenditure. Through utilizing the energy dissipating potential of such nutraceutical compounds, the possibility exists to provide a therapeutic solution to correct the energy imbalance that underlines obesity.
    Language English
    Publishing date 2016-12-03
    Publishing country England
    Document type Review ; Journal Article
    ISSN 1743-7075
    ISSN 1743-7075
    DOI 10.1186/s12986-016-0150-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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