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  1. Article: Involuntary Career Changes: A Lonesome Social Experience.

    Masdonati, Jonas / Frésard, Caroline É / Parmentier, Michaël

    Frontiers in psychology

    2022  Volume 13, Page(s) 899051

    Abstract: Like any other career process, career changes are influenced by relationships. Moreover, involuntary career changes are a challenging, yet understudied, career transition. Based on a relational perspective of work and careers, we investigated the way ... ...

    Abstract Like any other career process, career changes are influenced by relationships. Moreover, involuntary career changes are a challenging, yet understudied, career transition. Based on a relational perspective of work and careers, we investigated the way people's social environment affects the process and experience of involuntary career changes. Specifically, we aimed to identify the sources of relational influences and to understand how these influences affect career changes. Semi-structured interviews were carried out with 14 adults who were forced to change career because of unemployment or health issues. Through thematic analysis, we identified three sources of relational influences (personal, work, and institutional environment) and three forms of influence that others had on career changes (positive, negative, and ambivalent). These influences manifested at four distinct moments of the process: When participants were leaving their former job, when they were shifting between their former occupation and a new livelihood, when they were exploring new career options, or when they were trying to implement their new career plan. Overall, results suggest that involuntary career changes are deeply shaped by heterogeneous and differentiated relational influences. The effect of the personal environment varied depending on the moment of the career change process. In particular, family and friends tended to be perceived as barriers when it came to shifting from the old to a new occupation and implementing a new career plan. The work environment mostly had a negative effect on the career change experience, suggesting the labor market might be somewhat refractory toward adult career changers. Institutions played a critical role throughout the change process, with support structures often being perceived as inappropriate, but with guidance professionals generally recognizing participants' difficulties. Moreover, diverse forms of ambivalence characterized the identified relational influences, which were sometimes both appreciated and avoided or had ambiguous and fluctuating effects. Finally, although being a fundamentally social experience, involuntary career changes were also characterized by moments of loneliness that reflected the inadequacy of available support and a sense of shame associated with the status of career changer. Study limitations, research perspectives, and practical implications at the labor market, institutional, and individual levels are addressed.
    Language English
    Publishing date 2022-06-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2022.899051
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: How Do Spelling, Handwriting Speed, and Handwriting Quality Develop During Primary School? Cross-Classified Growth Curve Analysis of Children's Writing Development.

    Gosse, Claire / Parmentier, Michael / Van Reybroeck, Marie

    Frontiers in psychology

    2021  Volume 12, Page(s) 685681

    Abstract: Aim: ...

    Abstract Aim:
    Language English
    Publishing date 2021-07-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2021.685681
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: A New Dioxazolone for the Synthesis of 1,2-Aminoalcohols via Iridium(III)-Catalyzed C(sp

    Antien, Kevin / Geraci, Andrea / Parmentier, Michael / Baudoin, Olivier

    Angewandte Chemie (International ed. in English)

    2021  Volume 60, Issue 42, Page(s) 22948–22955

    Abstract: Vicinal aminoalcohols are widespread structural motifs in bioactive molecules. We report the development of a new dioxazolone reagent containing a p-nitrophenyldifluoromethyl group, which 1. displays a good safety profile; 2. shows a remarkably high ... ...

    Abstract Vicinal aminoalcohols are widespread structural motifs in bioactive molecules. We report the development of a new dioxazolone reagent containing a p-nitrophenyldifluoromethyl group, which 1. displays a good safety profile; 2. shows a remarkably high reactivity in the oxime-directed iridium(III)-catalyzed amidation of unactivated C(sp
    Language English
    Publishing date 2021-09-08
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/anie.202110019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Interface-rich Aqueous Systems for Sustainable Chemical Synthesis.

    Kaldre, Dainis / Gallou, Fabrice / Sparr, Christof / Parmentier, Michael

    Chimia

    2019  Volume 73, Issue 9, Page(s) 714–719

    Abstract: Mimicking an enzyme's exquisite activity and selectivity is a long-standing goal for sustainable chemical method development in aqueous media. The use of interface-rich aqueous systems, such as single-chain polymers, micelles and vesicle membranes ... ...

    Abstract Mimicking an enzyme's exquisite activity and selectivity is a long-standing goal for sustainable chemical method development in aqueous media. The use of interface-rich aqueous systems, such as single-chain polymers, micelles and vesicle membranes recently emerged as strategy to emulate the compartmentalization of natural systems. In aqueous solution, aggregates such as micelles or microemulsion droplets are formed, providing reaction environments different from bulk solutions that frequently improve selectivity and accelerate reaction rates for a wide array of chemical transformations. We present here selected examples of interface-rich aqueous systems and discuss the advantages they offer for chemical synthesis. In particular metal-catalyzed cross-coupling reactions are highlighted and future challenges to perform reactions in interface-rich aqueous media are discussed.
    Language English
    Publishing date 2019-09-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1516-7
    ISSN 0009-4293
    ISSN 0009-4293
    DOI 10.2533/chimia.2019.714
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Implementation of micelle-enabled C(sp

    Wu, Bin / Ye, Ning / Zhao, Kangming / Shi, Min / Liao, Jiayu / Zhang, Jing / Chen, Wei / Li, Xianzhong / Han, Yufeng / Cortes-Clerget, Margery / Regnier, Morgan Louis / Parmentier, Michael / Mathes, Christian / Rampf, Florian / Gallou, Fabrice

    Chemical communications (Cambridge, England)

    2024  Volume 60, Issue 17, Page(s) 2349–2352

    Abstract: A sustainable C( ... ...

    Abstract A sustainable C(sp
    MeSH term(s) Micelles ; Solvents ; Water ; Catalysis
    Chemical Substances Micelles ; Solvents ; Water (059QF0KO0R)
    Language English
    Publishing date 2024-02-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472881-3
    ISSN 1364-548X ; 1359-7345 ; 0009-241X
    ISSN (online) 1364-548X
    ISSN 1359-7345 ; 0009-241X
    DOI 10.1039/d3cc05916b
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Synthesis and Physicochemical Properties of 2-SF

    Debrauwer, Vincent / Leito, Ivo / Lõkov, Märt / Tshepelevitsh, Sofja / Parmentier, Michael / Blanchard, Nicolas / Bizet, Vincent

    ACS organic & inorganic Au

    2021  Volume 1, Issue 2, Page(s) 43–50

    Abstract: Structural diversity in heterocyclic chemistry is key to unlocking new properties and modes of action. In this regard, heterocycles embedding emerging fluorinated substituents hold great promise. Herein is described a strategy to access 2- ... ...

    Abstract Structural diversity in heterocyclic chemistry is key to unlocking new properties and modes of action. In this regard, heterocycles embedding emerging fluorinated substituents hold great promise. Herein is described a strategy to access 2-SF
    Language English
    Publishing date 2021-07-06
    Publishing country United States
    Document type Journal Article
    ISSN 2694-247X
    ISSN (online) 2694-247X
    DOI 10.1021/acsorginorgau.1c00010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Micelle enabled C(sp²)–C(sp³) cross-electrophile coupling in water via synergistic nickel and copper catalysis

    Ye, Ning / Wu, Bin / Zhao, Kangming / Ge, Xiaobin / Zheng, Yu / Shen, Xiaodong / Shi, Lei / Cortes-Clerget, Margery / Regnier, Morgan Louis / Parmentier, Michael / Gallou, Fabrice

    Chemical communications. 2021 Aug. 3, v. 57, no. 62

    2021  

    Abstract: A robust and sustainable C(sp²)–C(sp³) cross-electrophile coupling was developed via nickel/copper synergistic catalysis under micellar conditions. This protocol provided a general method to access alkylated arenes with good to excellent yields on a very ...

    Abstract A robust and sustainable C(sp²)–C(sp³) cross-electrophile coupling was developed via nickel/copper synergistic catalysis under micellar conditions. This protocol provided a general method to access alkylated arenes with good to excellent yields on a very large scale.
    Keywords aromatic hydrocarbons ; catalytic activity ; micelles ; nickel
    Language English
    Dates of publication 2021-0803
    Size p. 7629-7632.
    Publishing place The Royal Society of Chemistry
    Document type Article
    ZDB-ID 1472881-3
    ISSN 1364-548X ; 1359-7345 ; 0009-241X
    ISSN (online) 1364-548X
    ISSN 1359-7345 ; 0009-241X
    DOI 10.1039/d1cc02885e
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: Micelle-Enabled Suzuki-Miyaura Cross-Coupling of Heteroaryl Boronate Esters.

    Guo, Pengfei / Zhang, Hao / Zhou, Jianguang / Gallou, Fabrice / Parmentier, Michael / Wang, Hui

    The Journal of organic chemistry

    2018  Volume 83, Issue 14, Page(s) 7523–7527

    Abstract: We report a micellar protocol for Suzuki-Miyaura cross-coupling of heteroaryl boronic esters with aryl or heteroaryl halides. The micellar catalysis enables this coupling reaction to run under mild conditions, which avoids the decomposition of heteroaryl ...

    Abstract We report a micellar protocol for Suzuki-Miyaura cross-coupling of heteroaryl boronic esters with aryl or heteroaryl halides. The micellar catalysis enables this coupling reaction to run under mild conditions, which avoids the decomposition of heteroaryl boronate esters and allows for high chemoselectivity for cross-coupling reaction with 6-chloropridine-2-boronic ester. The micellar protocol expands the scope of the cross-coupling reaction with challenging heteroaryl boronic esters and complements the existing cross-coupling methods for construction of heterobiaryl building blocks.
    Language English
    Publishing date 2018-06-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 123490-0
    ISSN 1520-6904 ; 0022-3263
    ISSN (online) 1520-6904
    ISSN 0022-3263
    DOI 10.1021/acs.joc.8b00257
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  9. Article ; Online: Iridium-catalyzed H/D exchange: ligand complexes with improved efficiency and scope.

    Parmentier, Michael / Hartung, Thomas / Pfaltz, Andreas / Muri, Dieter

    Chemistry (Weinheim an der Bergstrasse, Germany)

    2014  Volume 20, Issue 36, Page(s) 11496–11504

    Abstract: Hydrogen isotope exchange (HIE) is one of the most attractive tools for the introduction of deuterium or tritium to an organic compound. Herein, iridium complexes with N,P-ligands, highly active catalysts for asymmetric double bond reductions, have been ... ...

    Abstract Hydrogen isotope exchange (HIE) is one of the most attractive tools for the introduction of deuterium or tritium to an organic compound. Herein, iridium complexes with N,P-ligands, highly active catalysts for asymmetric double bond reductions, have been tested for their HIE capabilities. Electron-rich ligands, containing dicyclohexylphosphines or phosphinites, have been identified as excellent ligands for efficient deuterium incorporation. Substrates with strong directing groups, that is, pyridines, ketones, and amides, as well as weak ligating units, such as, nitro, sulfones, and sulfonamides, could be labeled efficiently. With the addition of tris(pentafluorophenyl) borane to the reaction mixture, also highly deactivating nitrile substituents were well tolerated in the reaction. Based on the excellent results obtained with the chiral ThrePhox ligand, a structurally simpler, achiral ligand was developed. The iridium complex containing this ligand, proved to be a powerful catalyst for HIE reactions.
    MeSH term(s) Catalysis ; Coordination Complexes/chemistry ; Deuterium/chemistry ; Hydrogen/chemistry ; Iridium/chemistry ; Ligands
    Chemical Substances Coordination Complexes ; Ligands ; Iridium (44448S9773) ; Hydrogen (7YNJ3PO35Z) ; Deuterium (AR09D82C7G)
    Language English
    Publishing date 2014-09-01
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1478547-x
    ISSN 1521-3765 ; 0947-6539
    ISSN (online) 1521-3765
    ISSN 0947-6539
    DOI 10.1002/chem.201402078
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  10. Article ; Online: Switching from organic solvents to water at an industrial scale

    Parmentier, Michael / Gabriel, Christopher M. / Guo, Pengfei / Isley, Nicholas A. / Zhou, Jianguang / Gallou, Fabrice

    Current Opinion in Green and Sustainable Chemistry. 2017,

    2017  

    Abstract: The paper presents the most recent advances in applications of alternative medium to replace polar aprotic solvents such as dimethylformamide (DMF), dimethylacetamide (DMAc) or N-methyl-2-pyrrolidone (NMP). Focus is made on the use of nonionic designer ... ...

    Abstract The paper presents the most recent advances in applications of alternative medium to replace polar aprotic solvents such as dimethylformamide (DMF), dimethylacetamide (DMAc) or N-methyl-2-pyrrolidone (NMP). Focus is made on the use of nonionic designer surfactant (e.g. TPGS-750-M) in water instead of traditional organic solvents. Much attention is given to its applications to several commonly used transformations in active pharmaceutical ingredient (API) synthesis, such as amidation reactions, Suzuki-Miyaura cross-couplings, nitro group reductions, and aromatic nucleophilic substitutions. Case studies of successful uses to attain improved green processes are included. Future directions and most recent results using tailor-made reagents suitable for micellar environments are given.
    Keywords designer surfactant ; TPGS-750-M ; alternative solvent ; water ; selectivity
    Language English
    Publishing place Elsevier B.V.
    Document type Article ; Online
    Note Pre-press version
    ISSN 2452-2236
    DOI 10.1016/j.cogsc.2017.06.004
    Database NAL-Catalogue (AGRICOLA)

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