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Book ; Conference proceedings: Resúmenes de comunicaciones / XXII Congreso Nacional de Cirugía

Parrilla Paricio, P.

Madrid, 9 - 13 de noviembre de 1998

(Cirugía española ; 64, Supl. 1)

1998

Event/congress	Congreso Nacional de Cirugía (22, 1998, Madrid)
Author's details	[presidente: P. Parrilla Paricio]
Series title	Cirugía española ; 64, Supl. 1 Cirugía Española
Collection	Cirugía Española
Language	Spanish
Size	561 S. : graph. Darst.
Publisher	Asociacion Española de Cirujanos
Publishing place	Madrid
Publishing country	Spain
Document type	Book ; Conference proceedings
HBZ-ID	HT009516200
Database	Catalogue ZB MED Medicine, Health

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Zs B 96 -64,Supl.1-	verfügbar in Königswinter	Königswinter

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Article ; Online: Papillary thyroid microcarcinoma with minimal extrathyroidal extension. Is its course so indolent that it requires a less aggressive treatment?

Ruiz Pardo, J / Ríos Zambudio, A / Rodríguez González, J M / Paredes Quiles, M / Soriano Giménez, V / Oviedo Ramírez, M I / Hernández Martínez, A M / Parrilla Paricio, P

Revista clinica espanola

2021 Volume 221, Issue 3, Page(s) 131–138

Abstract: Background: Although the incidence of papillary thyroid microcarcinoma (PTMC) has increased in recent decades, the role played by minimal extrathyroidal extension (mETE) in the prognosis of PTMC is still unclear. The aim of this study is to analyze the ... ...

Abstract	Background: Although the incidence of papillary thyroid microcarcinoma (PTMC) has increased in recent decades, the role played by minimal extrathyroidal extension (mETE) in the prognosis of PTMC is still unclear. The aim of this study is to analyze the factors associated with PTMC with mETE and its long-term prognosis. Material and methods: We conducted a retrospective study on patients with a histological diagnosis of PTMC. We excluded patients who had previously undergone thyroid surgery, those who had other synchronous malignancies, those with an ectopic location of the PTMC, and those lost to follow-up within two years. We compared group 1 (PTMC without extrathyroidal extension) to group 2 (PTMC with mETE) and performed a multivariate analysis. Results: We observed PTMC with mETE in 11.2% (n = 18) of patients. On the multivariate analysis, mETE was associated with an age ≥45 years (OR: 4.383; 95% CI: 1.051-18.283, p = .043), tumor size ≥8 mm (OR: 5.913; 95% CI: 1.795-19.481; p = .003), bilaterality (OR: 4.430; 95% CI: 1.294-15.173; p = .018) and metastatic lymph nodes (OR: 12.588; 95% CI: 2.919-54.280; p = .001). Over the mean follow-up period of 119.8 ± 65 months, one case of recurrence was detected in group 2 (0% vs. 5.6%; p = .112). No patients died of the disease. Disease-free survival was lower in group 2 (124.9 ± 5.6 vs. 97.4 ± 10.3 months; p = .034). Conclusions: The mETE of PTMC is a factor of worse prognosis associated with the presence of metastatic lymph nodes and a lower rate of disease-free survival.
MeSH term(s)	Carcinoma, Papillary/epidemiology ; Humans ; Lymphatic Metastasis ; Middle Aged ; Retrospective Studies ; Risk Factors ; Thyroid Neoplasms/epidemiology
Language	English
Publishing date	2021-02-15
Publishing country	Spain
Document type	Journal Article
ISSN	2254-8874
ISSN (online)	2254-8874
DOI	10.1016/j.rceng.2019.12.012
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Cooperation in surgery of the 21

Gil Martínez, José / Rodríguez González, José Manuel / Parrilla Paricio, Pascual

Cirugia espanola

2018 Volume 96, Issue 8, Page(s) 466–472

Abstract: The need for healthcare cooperation in low- and middle-income countries is known and is implemented day by day. However, the surgical sanitary assistance in these countries in the ... ...

Title translation	Cooperación en cirugía en el siglo XXI.
Abstract	The need for healthcare cooperation in low- and middle-income countries is known and is implemented day by day. However, the surgical sanitary assistance in these countries in the 21
MeSH term(s)	Developing Countries ; Humans ; International Cooperation ; Poverty ; Surgical Procedures, Operative
Language	Spanish
Publishing date	2018-08-31
Publishing country	Spain
Document type	Journal Article
ISSN	2173-5077
ISSN (online)	2173-5077
DOI	10.1016/j.ciresp.2018.07.002
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Article: Fulminant liver failure secondary to submassive hepatic necrosis in a patient treated with Orlistat. A case report.

Martínez Insfran, Luis Alberto / Alconchel Gago, Felipe / Parrilla Paricio, Pascual

Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva

2018 Volume 111, Issue 1, Page(s) 83

Abstract: Orlistat is an intestinal lipase inhibitor drug that is recommended in obese patients along with a hypocaloric diet. Although the most frequent secondary effect is steatorrhea, fulminant liver failure has also been associated with this drug, which has ... ...

Abstract	Orlistat is an intestinal lipase inhibitor drug that is recommended in obese patients along with a hypocaloric diet. Although the most frequent secondary effect is steatorrhea, fulminant liver failure has also been associated with this drug, which has required liver transplantation in 3 patients. We present the case of a 42-year-old obese male.
MeSH term(s)	Adult ; Anti-Obesity Agents/adverse effects ; Fatty Liver/drug therapy ; Humans ; Liver Failure, Acute/chemically induced ; Male ; Massive Hepatic Necrosis/chemically induced ; Massive Hepatic Necrosis/complications ; Obesity/drug therapy ; Orlistat/adverse effects
Chemical Substances	Anti-Obesity Agents ; Orlistat (95M8R751W8)
Language	English
Publishing date	2018-10-16
Publishing country	Spain
Document type	Case Reports ; Letter
ZDB-ID	1070381-0
ISSN	1130-0108 ; 0212-7512
ISSN	1130-0108 ; 0212-7512
DOI	10.17235/reed.2018.5740/2018
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Article ; Online: Papillary thyroid microcarcinoma with minimal extrathyroidal extension. Is its course so indolent that it requires a less aggressive treatment?

Ruiz Pardo, J / Ríos Zambudio, A / Rodríguez González, J M / Paredes Quiles, M / Soriano Giménez, V / Oviedo Ramírez, M I / Hernández Martínez, A M / Parrilla Paricio, P

Revista clinica espanola

2020 Volume 221, Issue 3, Page(s) 131–138

Title translation	Microcarcinoma papilar de tiroides con extensión extratiroidea mínima. ¿Tiene un curso tan indolente para precisar un tratamiento menos intensivo?
Abstract	Background: Although the incidence of papillary thyroid microcarcinoma (PTMC) has increased in recent decades, the role played by minimal extrathyroidal extension (mETE) in the prognosis of PTMC is still unclear. The aim of this study is to analyze the factors associated with PTMC with mETE and its long-term prognosis. Material and methods: We conducted a retrospective study on patients with a histological diagnosis of PTMC. We excluded patients who had previously undergone thyroid surgery, those who had other synchronous malignancies, those with an ectopic location of the PTMC, and those lost to follow-up within 2years. We compared group 1 (PTMC without extrathyroidal extension) to group 2 (PTMC with mETE) and performed a multivariate analysis. Results: We observed PTMC with mETE in 11.2% (n=18) of patients. On the multivariate analysis, mETE was associated with age ≥45 years (OR: 4.383; 95% CI: 1.051-18.283, p = .043), tumor size ≥8mm (OR: 5.913; 95% CL: 1.795-19.481; p = .003), bilaterality (OR: 4.430; 95% CI: 1.294-15.173; p = .018) and metastatic lymph nodes (OR: 12.588; 95% CI: 2.919-54.280; p = .001). During a mean follow-up of 119.8±65 months, one recurrence was detected in group 2 (0% vs. 5.6%; p = .112). No patients died of the disease. Disease-free survival was lower in group 2 (124.9±5.6 vs. 97.4±10.3 months; p = .034). Conclusions: The mETE of PTMC is a factor of worse prognosis associated with the presence of metastatic lymph nodes and a lower rate of disease-free survival.
Language	Spanish
Publishing date	2020-03-23
Publishing country	Spain
Document type	Journal Article
ZDB-ID	123597-7
ISSN	1578-1860 ; 0014-2565 ; 0014-2565
ISSN (online)	1578-1860 ; 0014-2565
ISSN	0014-2565
DOI	10.1016/j.rce.2019.12.010
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Article: Indicaciones y resultados del trasplante hepático en la polineuropatía amiloidótica familiar tipo I.

Parrilla Paricio, P

Gastroenterologia y hepatologia

1999 Volume 22 Suppl 1, Page(s) 27–31

Title translation	Indications and results of liver transplant in type I familial amyloid polyneuropathy.
MeSH term(s)	Adult ; Amyloid Neuropathies/epidemiology ; Amyloid Neuropathies/surgery ; Biomarkers ; Global Health ; Humans ; Incidence ; Liver Transplantation ; Middle Aged ; Prealbumin/metabolism
Chemical Substances	Biomarkers ; Prealbumin
Language	Spanish
Publishing date	1999-02
Publishing country	Spain
Document type	Journal Article
ZDB-ID	632502-6
ISSN	0210-5705
ISSN	0210-5705
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Article ; Online: Surgical oncology in patients aged 80 years and older is associated with increased postoperative morbidity and mortality: A systematic review and meta-analysis of literature over 25 years.

Lopez-Lopez, V / Gómez-Ruiz, A J / Eshmuminov, D / Cascales-Campos, P A / Alconchel, F / Arevalo-Perez, J / Robles Campos, R / Parrilla Paricio, P

Surgical oncology

2019 Volume 33, Page(s) 81–95

Abstract: Background: The study aim is to analyze the evolution over the last 25 years of the results reported after abdominal oncological surgery in patients aged 80 years of age and older. The primary endpoint was morbidity and mortality in this group of ... ...

Abstract	Background: The study aim is to analyze the evolution over the last 25 years of the results reported after abdominal oncological surgery in patients aged 80 years of age and older. The primary endpoint was morbidity and mortality in this group of patients; the secondary endpoint was overall survival. Methods: A systematic search strategy was used to browse through Medline/PubMed, EMBASE, Scopus, ClinicalTrials.gov, Cochrane Database of Systematic Reviews, and Cochrane Central Register of Controlled Trials using a combination of standardized index terms. Studies published between 1997 and 2017 were selected. Only those studies that showed morbidity and mortality after digestive and hepatobiliary tract oncological surgery in individuals aged 80 years and older were included. The PROSPERO registration number is CRD42018087921. PRISMA and MOOSE guidelines were applied. Results: A total of 79 studies were included, categorized by origin of malignancy: esophageal (7), stomach (26), liver (4), pancreas (19), and colorectal (23). Compared with the non-elderly group, the elderly group had similar esophageal morbidity with higher mortality (RR 2.51, 1.50 to 4.21; P = 0.0005); higher gastric morbidity (RR 1.25, 1.09 to 1.43; P = 0.001), and mortality (RR 2.51, 1.81 to 3.49; P = 0.0001); similar liver morbidity and mortality; higher pancreatic morbidity (RR 1.17, 1.03 to 1.33; P = 0.02) and mortality (RR 2.37, 1.86 to 3.03; P < 0.00001); and similar colorectal morbidity with higher mortality (RR 4.44, 1.91 to 10.32; P = 0.005). Conclusion: Oncological surgery of most abdominal visceral tumors is associated with increased morbidity and mortality in patients older than 80 years.
MeSH term(s)	Aged, 80 and over ; Colorectal Neoplasms/surgery ; Digestive System Neoplasms/surgery ; Esophageal Neoplasms/surgery ; Humans ; Liver Neoplasms/surgery ; Pancreatic Neoplasms/surgery ; Postoperative Complications/epidemiology ; Postoperative Complications/mortality ; Stomach Neoplasms/surgery ; Surgical Oncology
Language	English
Publishing date	2019-12-20
Publishing country	Netherlands
Document type	Journal Article ; Meta-Analysis ; Systematic Review
ZDB-ID	1107810-8
ISSN	1879-3320 ; 0960-7404
ISSN (online)	1879-3320
ISSN	0960-7404
DOI	10.1016/j.suronc.2019.12.007
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Article ; Online: Primary hyperparathyroidism associated with MEN 1: Experience in 71 cases.

Balsalobre Salmeron, María / Rodriguez Gonzalez, Jose Manuel / Ríos, Antonio / Febrero, Beatriz / Parrilla Paricio, Pascual

Cirugia espanola

2018 Volume 96, Issue 10, Page(s) 627–633

Abstract: Introduction: Primary hyperparathyroidism (pHPT) in MEN 1 is characterized by multiglandular disease and early involvement of parathyroid glands at different times. Persistence and recurrence range from 25%-35%. The purpose was: a) to describe the ... ...

Title translation	Hiperparatiroidismo primario asociado a neoplasia endocrina múltiple tipo 1 (MEN 1). Experiencia en 71 casos.
Abstract	Introduction: Primary hyperparathyroidism (pHPT) in MEN 1 is characterized by multiglandular disease and early involvement of parathyroid glands at different times. Persistence and recurrence range from 25%-35%. The purpose was: a) to describe the experience and the treatment of patients with pHPT in MEN 1; b) to analyze the variables related with clinical presentation and recurrence. Method: A total of 97 patients with MEN 1 were diagnosed in a tertiary hospital. A retrospective analysis was made in patients with pHPT (n=71). Study variables: age at diagnosis, mutation, clinical presentation, laboratory tests, surgical technique, and recurrence of HPT. Results: Mean age was 38 years, and 50 patients were asymptomatic. The surgical technique was: subtotal parathyroidectomy (n=55), resection of three glands (n=7), and resection of less glands (n=9). Transcervical thymectomy was performed in 53 patients. Mean follow-up was 102.9 months. There were 21 recurrences, There were correlations between age at diagnosis and serum calcium levels with the presence of symptoms (P<.0001). There were also correlations between recurrence and surgical technique (P<.03), non-association with thymectomy (P<.0001), and follow-up time (P<.03). Conclusion: Performing genetic and clinical screening allows us to make a diagnosis in the asymptomatic period and to provide early treatment for HPT in MEN 1. The recurrence rate is high, and follow-up time and the surgical technique used are risk factors for recurrence.
MeSH term(s)	Adolescent ; Adult ; Aged ; Female ; Humans ; Hyperparathyroidism, Primary/complications ; Hyperparathyroidism, Primary/surgery ; Male ; Middle Aged ; Multiple Endocrine Neoplasia Type 1/complications ; Recurrence ; Retrospective Studies ; Young Adult
Language	Spanish
Publishing date	2018-07-26
Publishing country	Spain
Document type	Journal Article
ISSN	2173-5077
ISSN (online)	2173-5077
DOI	10.1016/j.ciresp.2018.06.014
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Article: Indication for liver transplantation in a patient with a history of a gastric lymphoma.

Ruiz Pardo, José / Cascales Campos, Pedro Antonio / Parrilla Paricio, Pascual

Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva

2016 Volume 108, Issue 6, Page(s) 379

Abstract: The indication for liver transplantation in patients with history of lymphoma is little-known, and the references documented in the medical literature are still limited. We present the case of a 63-year-old man who was diagnosed with chronic hepatopathy ... ...

Abstract	The indication for liver transplantation in patients with history of lymphoma is little-known, and the references documented in the medical literature are still limited. We present the case of a 63-year-old man who was diagnosed with chronic hepatopathy due to HBV 15 years ago. He was operated on for hepatocellular carcinoma in the segment VI of the liver 4 years ago, finding a macronodular liver cirrhosis during the surgery. Fifteen months later, the patient was diagnosed with diffuse large B-cell gastric lymphoma (fig.1). After a good response to chemotherapy treatment with R-CHOP scheme, the patient has been in complete remission for 36 months. Currently, the patient has a Child-Pugh score of 5 points, MELD score of 6 points, an undetectable viral load and it does not exist any evidence of hepatocellular carcinoma recurrence. With respect to this case, could it be considered liver transplantation in any assumption or would it be rejected in any case due to the recent history of lymphoma? In this case report, it has decided to do a periodic follow-up of the patient, but because of the good prognosis of the lymphoma, liver transplantation may be performed in the case of hepatocellular recurrence, worsening of liver function (Child-Pugh B or C) or fulminant hepatic failure due to HBV reactivation. There is not yet consensus about the interval between lymphoma remission and liver transplantation, therefore it recommends an individual oncologic evaluation in order to establish the recurrence risk before deciding on the indication for liver transplantation.
MeSH term(s)	Hepatitis B, Chronic/complications ; Hepatitis B, Chronic/surgery ; Humans ; Liver Transplantation/methods ; Lymphoma, Large B-Cell, Diffuse/complications ; Lymphoma, Non-Hodgkin/complications ; Male ; Middle Aged ; Stomach Neoplasms/complications
Language	English
Publishing date	2016-06
Publishing country	Spain
Document type	Case Reports ; Journal Article
ZDB-ID	1070381-0
ISSN	1130-0108 ; 0212-7512
ISSN	1130-0108 ; 0212-7512
DOI	10.17235/reed.2016.4191/2015
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Article ; Online: Asociación de tumores del estroma gastrointestinal con otros tumores primarios. Propuesta de una nueva clasificación.

Fernández Hernández, Juan Ángel / Olivares Ripoll, Vicente / Parrilla Paricio, Pascual

Medicina clinica

2016 Volume 147, Issue 9, Page(s) 405–409

Abstract: Additional primary malignancies in patients with gastrointestinal stromal tumor (GIST) is not only common but of growing interest in the scientific literature. This association is of great importance in terms of clinical challenge, diagnosis and therapy ... ...

Title translation	Additional primary malignancies in patients with gastrointestinal stromal tumors. Proposal for a new classification.
Abstract	Additional primary malignancies in patients with gastrointestinal stromal tumor (GIST) is not only common but of growing interest in the scientific literature. This association is of great importance in terms of clinical challenge, diagnosis and therapy as well as for the prognosis impact it implies. In the published series there is a tendency to group these patients to determine the specific and distinguishable characteristics of GIST associated with other malignancies. On the other hand, there is no general consensus or unified classification. This classification would be of great interest, as it would unify criteria, agree groups to compare different series and demonstrate whether the aetiology underlying both tumours and the GIST's own characteristics really vary according to the type in question. We undertook a medical literature review and proposed a new classification for patients with GIST associated with other tumours.
Language	Spanish
Publishing date	2016-11-04
Publishing country	Spain
Document type	Review ; Journal Article ; English Abstract
ZDB-ID	411607-0
ISSN	1578-8989 ; 0025-7753
ISSN (online)	1578-8989
ISSN	0025-7753
DOI	10.1016/j.medcli.2016.06.006
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