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  1. Article: 4-Hydroxysesamin, a Modified Natural Compound, Attenuates Neuronal Apoptosis After Ischemic Stroke via Inhibiting MAPK Pathway [Letter].

    Pasiana, Agriani Dini / Idrus, Hasta Handayani

    Neuropsychiatric disease and treatment

    2024  Volume 20, Page(s) 793–794

    Language English
    Publishing date 2024-04-03
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2186503-6
    ISSN 1178-2021 ; 1176-6328
    ISSN (online) 1178-2021
    ISSN 1176-6328
    DOI 10.2147/NDT.S468941
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Forsythoside B Mitigates Monocrotaline-Induced Pulmonary Arterial Hypertension via Blocking the NF-κB Signaling Pathway to Attenuate Vascular Remodeling [LETTER].

    Pasiana, Agriani Dini / Idrus, Hasta Handayani / Purnamasari, Istianah

    Drug design, development and therapy

    2024  Volume 18, Page(s) 1023–1024

    MeSH term(s) Humans ; Animals ; NF-kappa B/metabolism ; Monocrotaline ; Pulmonary Arterial Hypertension ; Vascular Remodeling ; Signal Transduction ; Pulmonary Artery/metabolism ; Disease Models, Animal ; Caffeic Acids ; Glucosides
    Chemical Substances NF-kappa B ; Monocrotaline (73077K8HYV) ; forsythoside B ; Caffeic Acids ; Glucosides
    Language English
    Publishing date 2024-04-02
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2451346-5
    ISSN 1177-8881 ; 1177-8881
    ISSN (online) 1177-8881
    ISSN 1177-8881
    DOI 10.2147/DDDT.S470685
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Central residues in prion protein PrP

    Pasiana, Agriani Dini / Miyata, Hironori / Chida, Junji / Hara, Hideyuki / Imamura, Morikazu / Atarashi, Ryuichiro / Sakaguchi, Suehiro

    The Journal of biological chemistry

    2022  Volume 298, Issue 9, Page(s) 102381

    Abstract: Conformational conversion of the cellular prion protein, ... ...

    Abstract Conformational conversion of the cellular prion protein, PrP
    MeSH term(s) Animals ; Mice ; Prion Diseases/genetics ; Prion Proteins/chemistry ; Prion Proteins/genetics ; Prions/pathogenicity ; Proline ; Protein Isoforms/genetics ; Translocation, Genetic
    Chemical Substances Prion Proteins ; Prions ; Protein Isoforms ; Proline (9DLQ4CIU6V)
    Language English
    Publishing date 2022-08-13
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2997-x
    ISSN 1083-351X ; 0021-9258
    ISSN (online) 1083-351X
    ISSN 0021-9258
    DOI 10.1016/j.jbc.2022.102381
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Neurotropic influenza A virus infection causes prion protein misfolding into infectious prions in neuroblastoma cells.

    Hara, Hideyuki / Chida, Junji / Uchiyama, Keiji / Pasiana, Agriani Dini / Takahashi, Etsuhisa / Kido, Hiroshi / Sakaguchi, Suehiro

    Scientific reports

    2021  Volume 11, Issue 1, Page(s) 10109

    Abstract: Misfolding of the cellular prion protein, ... ...

    Abstract Misfolding of the cellular prion protein, PrP
    MeSH term(s) Cell Line, Tumor ; Humans ; Influenza A virus/physiology ; Influenza, Human/genetics ; Influenza, Human/metabolism ; Influenza, Human/virology ; Neuroblastoma/genetics ; Neuroblastoma/metabolism ; Neuroblastoma/virology ; Prion Proteins/chemistry ; Prion Proteins/metabolism ; Protein Conformation ; Protein Folding
    Chemical Substances Prion Proteins
    Language English
    Publishing date 2021-05-12
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-021-89586-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Ethanolamine Is a New Anti-Prion Compound.

    Uchiyama, Keiji / Hara, Hideyuki / Chida, Junji / Pasiana, Agriani Dini / Imamura, Morikazu / Mori, Tsuyoshi / Takatsuki, Hanae / Atarashi, Ryuichiro / Sakaguchi, Suehiro

    International journal of molecular sciences

    2021  Volume 22, Issue 21

    Abstract: Prion diseases are a group of fatal neurodegenerative disorders caused by accumulation of proteinaceous infectious particles, or prions, which mainly consist of the abnormally folded, amyloidogenic prion protein, designated ... ...

    Abstract Prion diseases are a group of fatal neurodegenerative disorders caused by accumulation of proteinaceous infectious particles, or prions, which mainly consist of the abnormally folded, amyloidogenic prion protein, designated PrP
    MeSH term(s) Animals ; Brain/metabolism ; Cell Line, Tumor ; Ethanolamine/pharmacology ; Mice ; Mice, Inbred ICR ; PrPSc Proteins/antagonists & inhibitors ; PrPSc Proteins/genetics ; PrPSc Proteins/metabolism ; Prion Diseases/drug therapy ; Prion Diseases/genetics ; Prion Diseases/metabolism
    Chemical Substances PrPSc Proteins ; Ethanolamine (5KV86114PT)
    Language English
    Publishing date 2021-10-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms222111742
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Vaporized Hydrogen Peroxide and Ozone Gas Synergistically Reduce Prion Infectivity on Stainless Steel Wire.

    Hara, Hideyuki / Chida, Junji / Pasiana, Agriani Dini / Uchiyama, Keiji / Kikuchi, Yutaka / Naito, Tomoko / Takahashi, Yuichi / Yamamura, Junji / Kuromatsu, Hisashi / Sakaguchi, Suehiro

    International journal of molecular sciences

    2021  Volume 22, Issue 6

    Abstract: Prions are infectious agents causing prion diseases, which include Creutzfeldt-Jakob disease (CJD) in humans. Several cases have been reported to be transmitted through medical instruments that were used for preclinical CJD patients, raising public ... ...

    Abstract Prions are infectious agents causing prion diseases, which include Creutzfeldt-Jakob disease (CJD) in humans. Several cases have been reported to be transmitted through medical instruments that were used for preclinical CJD patients, raising public health concerns on iatrogenic transmissions of the disease. Since preclinical CJD patients are currently difficult to identify, medical instruments need to be adequately sterilized so as not to transmit the disease. In this study, we investigated the sterilizing activity of two oxidizing agents, ozone gas and vaporized hydrogen peroxide, against prions fixed on stainless steel wires using a mouse bioassay. Mice intracerebrally implanted with prion-contaminated stainless steel wires treated with ozone gas or vaporized hydrogen peroxide developed prion disease later than those implanted with control prion-contaminated stainless steel wires, indicating that ozone gas and vaporized hydrogen peroxide could reduce prion infectivity on wires. Incubation times were further elongated in mice implanted with prion-contaminated stainless steel wires treated with ozone gas-mixed vaporized hydrogen peroxide, indicating that ozone gas mixed with vaporized hydrogen peroxide reduces prions on these wires more potently than ozone gas or vaporized hydrogen peroxide. These results suggest that ozone gas mixed with vaporized hydrogen peroxide might be more useful for prion sterilization than ozone gas or vaporized hydrogen peroxide alone.
    MeSH term(s) Animals ; Brain/metabolism ; Brain/pathology ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Hydrogen Peroxide/chemistry ; Hydrogen Peroxide/pharmacology ; Mice ; Ozone/chemistry ; Ozone/pharmacology ; PrPC Proteins/antagonists & inhibitors ; PrPC Proteins/chemistry ; Prion Diseases/etiology ; Prion Diseases/prevention & control ; Prions ; Stainless Steel/chemistry
    Chemical Substances PrPC Proteins ; Prions ; Stainless Steel (12597-68-1) ; Ozone (66H7ZZK23N) ; Hydrogen Peroxide (BBX060AN9V)
    Language English
    Publishing date 2021-03-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms22063268
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Strain-Dependent Prion Infection in Mice Expressing Prion Protein with Deletion of Central Residues 91-106.

    Uchiyama, Keiji / Miyata, Hironori / Yamaguchi, Yoshitaka / Imamura, Morikazu / Okazaki, Mariya / Pasiana, Agriani Dini / Chida, Junji / Hara, Hideyuki / Atarashi, Ryuichiro / Watanabe, Hitomi / Kondoh, Gen / Sakaguchi, Suehiro

    International journal of molecular sciences

    2020  Volume 21, Issue 19

    Abstract: Conformational conversion of the cellular prion protein, ... ...

    Abstract Conformational conversion of the cellular prion protein, PrP
    MeSH term(s) Animals ; Baculoviridae/genetics ; Baculoviridae/metabolism ; Base Sequence ; Brain/metabolism ; Brain/pathology ; Cattle ; Cloning, Molecular ; Disease Susceptibility ; Encephalopathy, Bovine Spongiform/genetics ; Encephalopathy, Bovine Spongiform/metabolism ; Encephalopathy, Bovine Spongiform/pathology ; Gene Expression ; Injections, Intraventricular ; Mice ; Mice, Transgenic ; PrPC Proteins/chemistry ; PrPC Proteins/genetics ; PrPC Proteins/metabolism ; PrPSc Proteins/administration & dosage ; PrPSc Proteins/chemistry ; PrPSc Proteins/genetics ; PrPSc Proteins/metabolism ; Proteostasis Deficiencies/genetics ; Proteostasis Deficiencies/metabolism ; Proteostasis Deficiencies/pathology ; Recombinant Proteins/administration & dosage ; Recombinant Proteins/chemistry ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Scrapie/genetics ; Scrapie/metabolism ; Scrapie/pathology ; Sequence Deletion ; Species Specificity
    Chemical Substances PrPC Proteins ; PrPSc Proteins ; Recombinant Proteins
    Language English
    Publishing date 2020-10-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms21197260
    Database MEDical Literature Analysis and Retrieval System OnLINE

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