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  1. Article: Performance of Radiologists in the Evaluation of the Chest Radiography with the Use of a "new software score" in Coronavirus Disease 2019 Pneumonia Suspected Patients.

    Bagnera, Silvia / Bisanti, Francesca / Tibaldi, Claudia / Pasquino, Massimo / Berrino, Giulia / Ferraro, Roberta / Patania, Sebastiano

    Journal of clinical imaging science

    2020  Volume 10, Page(s) 40

    Abstract: Objectives: The purpose of this study is to assess the performance of radiologists using a new software called "COVID-19 score" when performing chest radiography on patients potentially infected by coronavirus disease 2019 (COVID-19) pneumonia. Chest ... ...

    Abstract Objectives: The purpose of this study is to assess the performance of radiologists using a new software called "COVID-19 score" when performing chest radiography on patients potentially infected by coronavirus disease 2019 (COVID-19) pneumonia. Chest radiography (or chest X-ray, CXR) and CT are important for the imaging diagnosis of the coronavirus pneumonia (COVID-19). CXR mobile devices are efficient during epidemies, because allow to reduce the risk of contagion and are easy to sanitize.
    Material and methods: From February-April 2020, 14 radiologists retrospectively evaluated a pool of 312 chest X-ray exams to test a new software function for lung imaging analysis based on radiological features and graded on a three-point scale. This tool automatically generates a cumulative score (0-18). The intra- rater agreement (evaluated with Fleiss's method) and the average time for the compilation of the banner were calculated.
    Results: Fourteen radiologists evaluated 312 chest radiographs of COVID-19 pneumonia suspected patients (80 males and 38 females) with an average age of 64, 47 years. The inter-rater agreement showed a Fleiss' kappa value of 0.53 and the intra-group agreement varied from Fleiss' Kappa value between 0.49 and 0.59, indicating a moderate agreement (considering as "moderate" ranges 0.4-0.6). The years of work experience were irrelevant. The average time for obtaining the result with the automatic software was between 7 s (e.g., zero COVID-19 score) and 21 s (e.g., with COVID-19 score from 6 to 12).
    Conclusion: The use of automatic software for the generation of a CXR "COVID-19 score" has proven to be simple, fast, and replicable. Implementing this tool with scores weighed on the number of lung pathological areas, a useful parameter for clinical monitoring could be available.
    Keywords covid19
    Language English
    Publishing date 2020-07-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2601233-9
    ISSN 2156-5597 ; 2156-7514
    ISSN (online) 2156-5597
    ISSN 2156-7514
    DOI 10.25259/JCIS_76_2020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Performance of Radiologists in the Evaluation of the Chest Radiography with the Use of a "new software score" in Coronavirus Disease 2019 Pneumonia Suspected Patients

    Bagnera, Silvia / Bisanti, Francesca / Tibaldi, Claudia / Pasquino, Massimo / Berrino, Giulia / Ferraro, Roberta / Patania, Sebastiano

    Journal of clinical imaging science

    Abstract: OBJECTIVES: The purpose of this study is to assess the performance of radiologists using a new software called "COVID-19 score" when performing chest radiography on patients potentially infected by coronavirus disease 2019 (COVID-19) pneumonia Chest ... ...

    Abstract OBJECTIVES: The purpose of this study is to assess the performance of radiologists using a new software called "COVID-19 score" when performing chest radiography on patients potentially infected by coronavirus disease 2019 (COVID-19) pneumonia Chest radiography (or chest X-ray, CXR) and CT are important for the imaging diagnosis of the coronavirus pneumonia (COVID-19) CXR mobile devices are efficient during epidemies, because allow to reduce the risk of contagion and are easy to sanitize MATERIAL AND METHODS: From February-April 2020, 14 radiologists retrospectively evaluated a pool of 312 chest X-ray exams to test a new software function for lung imaging analysis based on radiological features and graded on a three-point scale This tool automatically generates a cumulative score (0-18) The intra- rater agreement (evaluated with Fleiss's method) and the average time for the compilation of the banner were calculated RESULTS: Fourteen radiologists evaluated 312 chest radiographs of COVID-19 pneumonia suspected patients (80 males and 38 females) with an average age of 64, 47 years The inter-rater agreement showed a Fleiss' kappa value of 0 53 and the intra-group agreement varied from Fleiss' Kappa value between 0 49 and 0 59, indicating a moderate agreement (considering as "moderate" ranges 0 4-0 6) The years of work experience were irrelevant The average time for obtaining the result with the automatic software was between 7 s (e g , zero COVID-19 score) and 21 s (e g , with COVID-19 score from 6 to 12) CONCLUSION: The use of automatic software for the generation of a CXR "COVID-19 score" has proven to be simple, fast, and replicable Implementing this tool with scores weighed on the number of lung pathological areas, a useful parameter for clinical monitoring could be available
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #695248
    Database COVID19

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  3. Article ; Online: Ten-year results of accelerated hypofractionated adjuvant whole-breast radiation with concomitant boost to the lumpectomy cavity after conserving surgery for early breast cancer.

    Cante, Domenico / Petrucci, Edoardo / Sciacero, Piera / Piva, Cristina / Ferrario, Silvia / Bagnera, Silvia / Patania, Sebastiano / Mondini, Guido / Pasquino, Massimo / Casanova Borca, Valeria / Vellani, Giorgio / La Porta, Maria Rosa / Franco, Pierfrancesco

    Medical oncology (Northwood, London, England)

    2017  Volume 34, Issue 9, Page(s) 152

    Abstract: Accelerated hypofractionated whole-breast radiotherapy (WBRT) is considered a standard therapeutic option for early breast cancer (EBC) in the postoperative setting after breast conservation (BCS). A boost to the lumpectomy cavity may further increase ... ...

    Abstract Accelerated hypofractionated whole-breast radiotherapy (WBRT) is considered a standard therapeutic option for early breast cancer (EBC) in the postoperative setting after breast conservation (BCS). A boost to the lumpectomy cavity may further increase local control. We herein report on the 10-year results of a series of EBC patients treated after BCS with hypofractionated WBRT with a concomitant photon boost to the surgical bed over 4 weeks. Between 2005 and 2007, 178 EBC patients were treated with a basic course of radiotherapy consisting of 45 Gy to the whole breast in 20 fractions (2.25 Gy daily) with an additional boost dose of 0.25 Gy delivered concomitantly to the lumpectomy cavity, for an additional dose of 5 Gy. Median follow-up period was 117 months. At 10-year, overall, cancer-specific, disease-free survival and local control were 92.2% (95% CI 88.7-93.4%), 99.2% (95% CI 96.7-99.7%), 95.5% (95% CI 91.2-97.2%) and 97.3% (95% CI 94.5-98.9%), respectively. Only eight patients recurred. Four in-breast recurrences, two axillary node relapses and two metastatic localizations were observed. Fourteen patients died during the observation period due to other causes while breast cancer-related deaths were eight. At last follow-up, ≥G2 fibrosis and telangiectasia were seen in 7% and 5% of patients. No major lung and heart toxicities were observed. Cosmetic results were excellent/good in 87.8% of patients and fair/poor in 12.2%. Hypofractionated WBRT with concomitant boost to the lumpectomy cavity after BCS in EBC led to consistent clinical results at 10 years. Hence, it can be considered a valid treatment option in this setting.
    Language English
    Publishing date 2017-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1201189-7
    ISSN 1559-131X ; 0736-0118 ; 1357-0560
    ISSN (online) 1559-131X
    ISSN 0736-0118 ; 1357-0560
    DOI 10.1007/s12032-017-1020-4
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1899: Show issues Location:
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  4. Article ; Online: Correction to: Ten-year results of accelerated hypofractionated adjuvant whole-breast radiation with concomitant boost to the lumpectomy cavity after conserving surgery for early breast cancer.

    Cante, Domenico / Petrucci, Edoardo / Sciacero, Piera / Piva, Cristina / Ferrario, Silvia / Bagnera, Silvia / Patania, Sebastiano / Mondini, Guido / Pasquino, Massimo / Casanova Borca, Valeria / Vellani, Giorgio / La Porta, Maria Rosa / Franco, Pierfrancesco

    Medical oncology (Northwood, London, England)

    2017  Volume 35, Issue 1, Page(s) 11

    Abstract: An error inadvertently occurred in the discussion of the original publication when citing the local relapse rates of the EORTC 22881-10882 trial ('boost vs no boost trial'). ...

    Abstract An error inadvertently occurred in the discussion of the original publication when citing the local relapse rates of the EORTC 22881-10882 trial ('boost vs no boost trial').
    Language English
    Publishing date 2017-12-12
    Publishing country United States
    Document type Journal Article ; Published Erratum
    ZDB-ID 1201189-7
    ISSN 1559-131X ; 0736-0118 ; 1357-0560
    ISSN (online) 1559-131X
    ISSN 0736-0118 ; 1357-0560
    DOI 10.1007/s12032-017-1056-5
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1899: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
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  5. Article ; Online: Does accelerated hypofractionated adjuvant whole-breast radiotherapy increase mammographic density or change mammographic features?

    Bagnera, Silvia / Milanesio, Luisella / Brachet Cota, Piero B / Berrino, Carla / Cataldi, Aldo / Gatti, Giovanni / Mondini, Guido / Paino, Ovidio / Comello, Erika G / Orlassino, Renzo / Pasquino, Massimo / Cante, Domenico / La Porta, Maria R / Patania, Sebastiano / La Valle, Giovanni

    The British journal of radiology

    2015  Volume 88, Issue 1055, Page(s) 20150312

    Abstract: Objective: To compare mammographic features before and after accelerated hypofractionated adjuvant whole-breast radiotherapy (AWB-RT) and to evaluate possible appearance of modifications.: Methods: A retrospective review of 177 females before and ... ...

    Abstract Objective: To compare mammographic features before and after accelerated hypofractionated adjuvant whole-breast radiotherapy (AWB-RT) and to evaluate possible appearance of modifications.
    Methods: A retrospective review of 177 females before and after an AWB-RT treatment (follow-up ranging from 5 to 9 years) was performed by four radiologists focused in breast imaging who independently evaluated diffuse mammographic density patterns and reported on possible onset of focal alterations; modifications in density and fibrosis with parenchymal distortion were deemed as indicators of AWB-RT treatment impact in breast imaging.
    Results: Prevalent mammographic density (D) patterns in the 177 females evaluated were according to the American College of Radiology-Breast Imaging Reporting and Data System (ACR-BIRADS): D1, fibroadipose density (score percentage from 55.9% to 43.5%); and D2, scattered fibroglandular density (from 42.9% to 32.7%). No change in diffuse mammographic density and no significant difference in mammographic breast parenchymal structure were observed. "No change" was reported with score percentage from 87% to 79.6%. Appearance of fibrosis with parenchymal distortion was reported by all radiologists in only two cases (1.1%, p = 0.3); dystrophic calcification was identified with percentage score from 2.2% to 3.3% (small type) and from 9.6% to 12.9% (coarse type).
    Conclusion: No statistically significant changes in follow-up mammographies 5-9 years after AWB-RT were detected, justifying large-scale selection of AWB-RT treatment with no risk of altering radiological breast parameters of common use in tumour recurrence detection.
    Advances in knowledge: The hypofractionated radiotherapy (AWB-RT treatment) is a new proven, safe and effective modality in post-operative patients with early breast cancer with excellent local control and survival. In our study, the absence of changes in mammographic density patterns and in breast imaging before and after AWB-RT treatment (up to 5-9 years after radiotherapy) justifies large-scale use of AWB-RT treatment without hindrance in tumour recurrence diagnosis.
    MeSH term(s) Aged ; Aged, 80 and over ; Breast Density ; Breast Neoplasms/diagnostic imaging ; Breast Neoplasms/radiotherapy ; Breast Neoplasms/surgery ; Dose Fractionation, Radiation ; Female ; Humans ; Mammary Glands, Human/abnormalities ; Middle Aged ; Radiography ; Radiotherapy, Adjuvant ; Retrospective Studies
    Language English
    Publishing date 2015-09-22
    Publishing country England
    Document type Comparative Study ; Journal Article
    ZDB-ID 2982-8
    ISSN 1748-880X ; 0007-1285
    ISSN (online) 1748-880X
    ISSN 0007-1285
    DOI 10.1259/bjr.20150312
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    In stock of ZB MED Cologne/Königswinter

    Ue I Zs.11: Show issues Location:
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