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  1. Article ; Online: Artificial Intelligence and Neurosurgery: Tracking Antiplatelet Response Patterns for Endovascular Intervention.

    Saigal, Khushi / Patel, Anmol Bharat / Lucke-Wold, Brandon

    Medicina (Kaunas, Lithuania)

    2023  Volume 59, Issue 10

    Abstract: Platelets play a critical role in blood clotting and the development of arterial blockages. Antiplatelet therapy is vital for preventing recurring events in conditions like coronary artery disease and strokes. However, there is a lack of comprehensive ... ...

    Abstract Platelets play a critical role in blood clotting and the development of arterial blockages. Antiplatelet therapy is vital for preventing recurring events in conditions like coronary artery disease and strokes. However, there is a lack of comprehensive guidelines for using antiplatelet agents in elective neurosurgery. Continuing therapy during surgery poses a bleeding risk, while discontinuing it before surgery increases the risk of thrombosis. Discontinuation is recommended in neurosurgical settings but carries an elevated risk of ischemic events. Conversely, maintaining antithrombotic therapy may increase bleeding and the need for transfusions, leading to a poor prognosis. Artificial intelligence (AI) holds promise in making difficult decisions regarding antiplatelet therapy. This paper discusses current clinical guidelines and supported regimens for antiplatelet therapy in neurosurgery. It also explores methodologies like P2Y12 reaction units (PRU) monitoring and thromboelastography (TEG) mapping for monitoring the use of antiplatelet regimens as well as their limitations. The paper explores the potential of AI to overcome such limitations associated with PRU monitoring and TEG mapping. It highlights various studies in the field of cardiovascular and neuroendovascular surgery which use AI prediction models to forecast adverse outcomes such as ischemia and bleeding, offering assistance in decision-making for antiplatelet therapy. In addition, the use of AI to improve patient adherence to antiplatelet regimens is also considered. Overall, this research aims to provide insights into the use of antiplatelet therapy and the role of AI in optimizing treatment plans in neurosurgical settings.
    MeSH term(s) Humans ; Platelet Aggregation Inhibitors/therapeutic use ; Neurosurgery ; Artificial Intelligence ; Blood Platelets ; Coronary Artery Disease ; Hemorrhage/chemically induced ; Ischemia ; Thrombosis
    Chemical Substances Platelet Aggregation Inhibitors
    Language English
    Publishing date 2023-09-25
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina59101714
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6270: Show issues Location:
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  2. Article ; Online: Summative content analysis of the recommendations from Project ECHO Ontario Autism.

    Jane, Alanna / Kanigsberg, Lisa / Patel, Anmol / Eldon, Salina / Anagnostou, Evdokia / Brian, Jessica / Penner, Melanie

    Frontiers in rehabilitation sciences

    2023  Volume 4, Page(s) 1096314

    Abstract: Background: Practitioners report a lack of knowledge and confidence in treating autistic children, resulting in unmet healthcare needs. The Extension of Community Healthcare Outcomes (ECHO) Autism model addresses this through discussion of participant- ... ...

    Abstract Background: Practitioners report a lack of knowledge and confidence in treating autistic children, resulting in unmet healthcare needs. The Extension of Community Healthcare Outcomes (ECHO) Autism model addresses this through discussion of participant-generated cases, helping physicians provide best-practice care through co-created recommendations. Recommendations stemming from ECHO cases have yet to be characterized and may help guide the future care of autistic children. Our objective was to characterize and categorize case discussion recommendations from Project ECHO Ontario Autism to better identify gaps in clinician knowledge.
    Methods: We conducted a summative content analysis of all ECHO Ontario Autism case recommendations to identify categories of recommendations and their frequencies. Two researchers independently coded recommendations from five ECHO cases to develop the coding guide. They then each independently coded all remaining cases and recommendations from three cycles of ECHO held between October 2018 to July 2021, meeting regularly with the ECHO lead to consolidate the codes. A recommendation could be identified with more than one code if it pertained to multiple aspects of autism care. Categories from the various codes were identified and the frequency of each code was calculated.
    Results: Of the 422 recommendations stemming from 62 cases, we identified 55 codes across ten broad categories. Categories included accessing community resources (
    Conclusion: This is the first time that recommendations from ECHO Autism have been characterized and grouped into categories. Our results show that advice for autism identification and management spans many different facets of community-based care. Specific attention should be paid to providing continued access to education about autism, streamlining referrals to allied health providers, and a greater focus on patient- and family-centered care. Physicians should have continued access to autism education to help fill knowledge gaps and to facilitate families' service navigation.
    Language English
    Publishing date 2023-03-30
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2673-6861
    ISSN (online) 2673-6861
    DOI 10.3389/fresc.2023.1096314
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Is the situational judgment test a fair way of assessing candidates applying to the United Kingdom Foundation Programme?

    Ismail, Joanna / Patel, Anmol Bipin

    Advances in medical education and practice

    2019  Volume 10, Page(s) 413–414

    Language English
    Publishing date 2019-06-17
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2578539-4
    ISSN 1179-7258
    ISSN 1179-7258
    DOI 10.2147/AMEP.S186536
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  4. Article: Teaching by intimidation: medical students' perspective.

    Patel, Anmol Bipin / Kalkat, Harkaran Singh

    Advances in medical education and practice

    2019  Volume 10, Page(s) 303–304

    Language English
    Publishing date 2019-05-17
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2578539-4
    ISSN 1179-7258
    ISSN 1179-7258
    DOI 10.2147/AMEP.S184888
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Teaching models in the clinical years of medical education.

    Patel, Anmol Bipin / Kalkat, Harkaran Singh

    Advances in medical education and practice

    2019  Volume 10, Page(s) 309–310

    Language English
    Publishing date 2019-05-23
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2578539-4
    ISSN 1179-7258
    ISSN 1179-7258
    DOI 10.2147/AMEP.S186141
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Comparing Postoperative Taping vs Customized 3D Splints for Managing Nasal Edema after Rhinoplasty.

    Patel, Anmol / Townsend, Alexandra N / Gordon, Alexandra R / Schreiber, Jillian S / Tepper, Oren M / Layke, John

    Plastic and reconstructive surgery. Global open

    2023  Volume 11, Issue 9, Page(s) e5285

    Abstract: Background: Significant swelling after rhinoplasty can temporarily obscure results and lead to distress for patients and surgeons. We recently developed three dimensional (3D)-printed nasal splints that aim to protect the nose and limit edema by ... ...

    Abstract Background: Significant swelling after rhinoplasty can temporarily obscure results and lead to distress for patients and surgeons. We recently developed three dimensional (3D)-printed nasal splints that aim to protect the nose and limit edema by applying gentle compression. This prospective, randomized study compares postoperative nasal edema in patients being treated with traditional taping versus 3D-printed splints.
    Methods: Patients undergoing primary rhinoplasty (2019-2020) were randomized into two groups: taping versus 3D-printed splinting. For 12 weeks, patients either applied steri-strips to the dorsum and tip, or used 3D-printed splints, which were based on nasal simulations. The percentage change in volume (cm
    Results: Nasal taping (n = 34) demonstrated a volume reduction of 4.8%, 9.9%, 10.0%, 10.3%, and 10.6% (compared with baseline) at 2 weeks, 6 weeks, 3 months, 6 months, and 1 year, respectively. In contrast, the resolution of swelling with 3D splints (n = 36) was 5.0%, 8.6%, 11.0%, 14.9%, and 15.1% at the same time points. Inter-group comparison showed that 3D splints led to significantly less edema of the total nose at 6 months and 1 year (
    Conclusions: 3D-printed splints after rhinoplasty leads to a significant reduction of edema, most noticeable at 6 months and 1 year. This study suggests that customized 3D-printed splints offer an effective clinical alternative to traditional taping to reduce postoperative edema after rhinoplasty.
    Language English
    Publishing date 2023-09-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2851682-5
    ISSN 2169-7574 ; 2169-7574
    ISSN (online) 2169-7574
    ISSN 2169-7574
    DOI 10.1097/GOX.0000000000005285
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 7091: Show issues Location:
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  7. Article ; Online: The Impact of Alar Flare Reduction Goes Beyond Just the Ala.

    Gordon, Alexandra R / Patel, Anmol / Schreiber, Jillian E / Layke, John C / Tepper, Oren M

    Plastic and reconstructive surgery

    2023  Volume 152, Issue 4, Page(s) 755–762

    Abstract: Background: Alar flare reduction (AFR) is a widely used technique in rhinoplasty. Although the impact of AFR on the alar base has been well studied, its effect on the surrounding tissues is largely unknown. This study aims to elucidate the potential ... ...

    Abstract Background: Alar flare reduction (AFR) is a widely used technique in rhinoplasty. Although the impact of AFR on the alar base has been well studied, its effect on the surrounding tissues is largely unknown. This study aims to elucidate the potential effect of AFR on the overall nasal and perinasal anatomy.
    Methods: AFR was performed on cadavers ( n = 7) with sequential crescent-shaped alar excisions of 2, 4, and 6 mm. Two- and three-dimensional photographs were obtained at baseline and subsequent intervals. Analysis was performed with Adobe Photoshop and Vectra. Standardized landmarks were placed at the nasal tip point (NTP) and alar base point to quantify NTP vector distances, NTP surface distances, and alar crease angle.
    Results: The surface and vector distances between the NTP and alar base point decreased for increasing AFR intervals. AFR created a surface decrease of 1.90 ± 1.60, 3.54 ± 1.85, and 4.91 ± 1.89 mm, respectively. AFR created a vector decrease of 1.50 ± 1.14, 2.83 ± 1.37, and 3.97 ± 1.38 mm, respectively. NTP projection decreased by 0.54 ± 0.31 mm for 6-mm excision. AFR led to cheek elevation of 0.87 ± 0.70, 1.25 ± 0.60, and 1.96 ± 0.48 mm, respectively. This alar crease elevation blunted the transition between the cheek and upper lip skin at the level of the alar rim with the angle of this transition increasing 26.62 ± 12.78 degrees from baseline to 6 mm.
    Conclusions: Three-dimensional analysis demonstrates the influence of AFR on the alar base and surrounding perinasal contour. AFR results in nasal tip deprojection, alar crease elevation, and alar flare width narrowing. Further investigation into the impact of modifying the alar base on surrounding structures is warranted.
    MeSH term(s) Humans ; Nose/surgery ; Nose/anatomy & histology ; Rhinoplasty/methods ; Lip/surgery ; Cadaver ; Cheek/surgery
    Language English
    Publishing date 2023-02-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208012-6
    ISSN 1529-4242 ; 0032-1052 ; 0096-8501
    ISSN (online) 1529-4242
    ISSN 0032-1052 ; 0096-8501
    DOI 10.1097/PRS.0000000000010311
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uk I Zs.142: Show issues Location:
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  8. Article ; Online: 3D Printed Surgical Guides Applied in Rhinoplasty to Help Obtain Ideal Nasal Profile.

    Gordon, Alexandra R / Schreiber, Jillian E / Patel, Anmol / Tepper, Oren M

    Aesthetic plastic surgery

    2021  Volume 45, Issue 6, Page(s) 2852–2859

    Abstract: Introduction: As computer simulation for rhinoplasty continues to rise, the technology's utility extends beyond increasing patient conversion. Virtual simulation of the surgical result can assist with surgical planning and intraoperative decision-making. ...

    Abstract Introduction: As computer simulation for rhinoplasty continues to rise, the technology's utility extends beyond increasing patient conversion. Virtual simulation of the surgical result can assist with surgical planning and intraoperative decision-making. 3D printed anatomic models or surgical guides based on 3D images may help align surgeons with their original surgical plan. This study aims to evaluate the utility of 3D printed surgical guides as an intraoperative tool to help establish dorsal height and tip position.
    Methods: Patients undergoing rhinoplasty had preoperative virtual 3D surgical simulations performed. Simulations were used to create a 3D printed nasal kits containing ceramic models of the preoperative nose and simulated nose, sagittal contour guide, and customized postoperative nasal splint. Nasal guides were sterilized for continual intraoperative assessment of profile contour (i.e., dorsal height and tip position). Postoperative 3D images (1-3 months post-op) were then compared to preoperative simulations. The difference between z coordinates and y coordinates determined the difference in projection and rotation, respectively.
    Results: Fifteen patients met inclusion criteria for this study. With the use of 3D printed surgical guides, the final tip position was on average of 0.8±0.7mm from simulated projection and 0.3±0.2mm from simulated rotation. Similarly, projection for the cartilaginous and bony dorsum was within 1.0±0.8 and 0.8±0.7mm of the simulation, respectively.
    Conclusion: Virtual simulation is useful in defining aesthetic goals preoperatively, but the potential clinical value extends beyond this. 3D printed rhinoplasty guides extend the simulation's utility to decision-making intraoperatively. This technology offers a novel medium for anatomic reference, which may improve adherence to desired aesthetic goals.
    Level of evidence v: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine Ratings, please refer to Table of Contents or online Instructions to Authors www.springer.com/00266 .
    MeSH term(s) Computer Simulation ; Esthetics ; Humans ; Nasal Septum/surgery ; Nose/surgery ; Printing, Three-Dimensional ; Retrospective Studies ; Rhinoplasty ; Treatment Outcome
    Language English
    Publishing date 2021-06-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 532791-x
    ISSN 1432-5241 ; 0364-216X
    ISSN (online) 1432-5241
    ISSN 0364-216X
    DOI 10.1007/s00266-021-02350-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Defining Spatial and Temporal Resolution of Edema following Rhinoplasty: A Three-Dimensional Topographical Analysis.

    Gordon, Alexandra R / Schreiber, Jillian E / Patel, Anmol / Marcus, Ellen / Layke, John C / Tepper, Oren M

    Plastic and reconstructive surgery

    2022  Volume 150, Issue 4, Page(s) 928e–930e

    MeSH term(s) Ecchymosis ; Edema/etiology ; Humans ; Postoperative Complications/etiology ; Rhinoplasty/adverse effects ; Rhinoplasty/methods
    Language English
    Publishing date 2022-08-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208012-6
    ISSN 1529-4242 ; 0032-1052 ; 0096-8501
    ISSN (online) 1529-4242
    ISSN 0032-1052 ; 0096-8501
    DOI 10.1097/PRS.0000000000009528
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  10. Article ; Online: Current Trends in Ideal Nasal Aesthetics Show Younger Patients Have a Preference Toward Longer Augmented Noses.

    Patel, Anmol A / Gordon, Alexandra R / Townsend, Alexandra N / Shah, Jinesh / Garfein, Evan S / Tepper, Oren M

    Aesthetic surgery journal. Open forum

    2023  Volume 5, Page(s) ojad069

    Language English
    Publishing date 2023-08-04
    Publishing country England
    Document type Journal Article
    ISSN 2631-4797
    ISSN (online) 2631-4797
    DOI 10.1093/asjof/ojad069
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