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  1. Article ; Online: INJECTABLE FLUOCINOLONE IMPLANT FOR THE MANAGEMENT OF CHRONIC POSTSURGICAL CYSTOID MACULAR EDEMA IN VITRECTOMIZED EYES.

    Patel, Kishan G / Flores, Jessica / Abbey, Ashkan M

    Retina (Philadelphia, Pa.)

    2023  Volume 43, Issue 10, Page(s) 1732–1737

    Abstract: Purpose: Long-acting injectable steroids are changing the treatment paradigm for patients with chronic intraocular inflammation and cystoid macular edema (CME). We report the use of the fluocinolone implant 0.18 mg in patients with chronic postsurgical ... ...

    Abstract Purpose: Long-acting injectable steroids are changing the treatment paradigm for patients with chronic intraocular inflammation and cystoid macular edema (CME). We report the use of the fluocinolone implant 0.18 mg in patients with chronic postsurgical CME after pars plana vitrectomy.
    Methods: This is a retrospective case series of 24 vitrectomized eyes which received fluocinolone implant for the management postsurgical CME. Clinical outcomes and requirement for rescue therapy were studied.
    Results: Median length of follow-up was 19.3 months (range 8.3-23.2 months). There was an improvement in median central subfield thickness from 412 µ m (range 167-806 µ m) to 311 µ m (range 157-686 µ m) after fluocinolone implant ( P < 0.001). The injection burden decreased significantly after study treatment ( P < 0.001); however, there was no significant change in visual acuity ( P = 0.334). Eighteen eyes had control of CME that did not require additional intravitreal therapy. Four eyes had initially controlled but recurrent CME requiring intravitreal steroid therapy at median of 7.8 months (range 7.6-15.4 months). One eye never attained sufficient inflammatory control despite rescue therapy.
    Conclusion: Fluocinolone implant can be an effective treatment in vitrectomized patients with chronic postsurgical CME and can help decrease the overall injection burden.
    MeSH term(s) Humans ; Macular Edema/diagnosis ; Macular Edema/drug therapy ; Macular Edema/etiology ; Glucocorticoids ; Retrospective Studies ; Fluocinolone Acetonide
    Chemical Substances fluocinolone (CT1IX58L9S) ; Glucocorticoids ; Fluocinolone Acetonide (0CD5FD6S2M)
    Language English
    Publishing date 2023-06-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603192-4
    ISSN 1539-2864 ; 0275-004X
    ISSN (online) 1539-2864
    ISSN 0275-004X
    DOI 10.1097/IAE.0000000000003855
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Orbital compartment syndrome following primary scleral buckle surgery.

    Mei, Frank / Tajran, Jahan N / Mohamed, Mohamed R / Patel, Kishan G / Wang, Angeline L

    Retinal cases & brief reports

    2023  

    Abstract: Purpose: To illustrate a patient with orbital compartment syndrome following scleral buckle placement that was successfully treated with canthotomy and cantholysis.: Methods: Observational case report.: Results: A 26-year-old male underwent a ... ...

    Abstract Purpose: To illustrate a patient with orbital compartment syndrome following scleral buckle placement that was successfully treated with canthotomy and cantholysis.
    Methods: Observational case report.
    Results: A 26-year-old male underwent a primary scleral buckle repair for a chronic rhegmatogenous retinal detachment. On post-operative day four, the patient presented to the emergency room with pain and increased intraocular pressure (IOP). Initial treatment with conservative IOP lowering agents was unsuccessful. The patient was diagnosed with delayed orbital compartment syndrome and was successfully managed with lateral canthotomy and inferior cantholysis in addition to aggressive steroid and antibiotic medical management.
    Conclusion: Following scleral buckle placement with sub-tenon's anesthesia block, there may be a delayed presentation of orbital compartment syndrome. Recognition and management of this rare complication is important for preventing irreversible blindness.
    Language English
    Publishing date 2023-12-12
    Publishing country United States
    Document type Journal Article
    ISSN 1937-1578
    ISSN (online) 1937-1578
    DOI 10.1097/ICB.0000000000001533
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: TWENTY-FIVE AND TWENTY-SEVEN-GAUGE SUTURELESS INTRASCLERAL FIXATION OF INTRAOCULAR LENSES: Clinical Outcomes and Comparative Effectiveness of Haptic Flanging in a Large Single-Surgeon Series of 488 Eyes.

    Patel, Kishan G / Yazdani, Ava / Abbey, Ashkan M

    Retina (Philadelphia, Pa.)

    2021  Volume 41, Issue 12, Page(s) 2485–2490

    Abstract: Purpose: To describe the clinical outcomes and surgical technique in transconjunctival sutureless intrascleral fixation of intraocular lenses, including the effectiveness of haptic flanging and peripheral iridotomy.: Method: Retrospective series of ... ...

    Abstract Purpose: To describe the clinical outcomes and surgical technique in transconjunctival sutureless intrascleral fixation of intraocular lenses, including the effectiveness of haptic flanging and peripheral iridotomy.
    Method: Retrospective series of patients who underwent sutureless intrascleral fixation of three-piece intraocular lenses by a single surgeon.
    Results: A total of 488 eyes were included in this study. Mean follow-up was 444 days. Mean preoperative best-corrected visual acuity was 20/355, and mean postoperative best-corrected visual acuity was 20/39 (P < 0.001). Intraocular lens dislocation occurred during the postoperative period in 67 (13.7%), with the majority (65.7%) occurring within 3 months after surgery. Dislocation occurred in 13 of 196 (6.6%) flanged haptics versus 54 of 292 (18.5%) unflanged haptics (P < 0.001). Reverse pupillary block occurred in 7 of 231 eyes (3.0%) without intraoperative peripheral iridotomy but only in 1 of 257 eyes (0.4%) with iridotomy (P = 0.0297). Other complications included haptic exposure (1.2%), retinal detachment (1.0%), and endophthalmitis (0.4%).
    Conclusion: This is the largest reported series of sutureless intrascleral fixation of intraocular lenses using trocar cannulas. This technique is an effective surgical option with low complication rates. The authors recommend that haptic flanging and peripheral iridotomy be performed in all cases.
    MeSH term(s) Artificial Lens Implant Migration/surgery ; Humans ; Lens Implantation, Intraocular/methods ; Lenses, Intraocular ; Postoperative Complications ; Pseudophakia/physiopathology ; Retrospective Studies ; Sclera/surgery ; Surgical Instruments ; Sutureless Surgical Procedures/methods ; Treatment Outcome ; Visual Acuity/physiology ; Vitrectomy
    Language English
    Publishing date 2021-06-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603192-4
    ISSN 1539-2864 ; 0275-004X
    ISSN (online) 1539-2864
    ISSN 0275-004X
    DOI 10.1097/IAE.0000000000003243
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Uveitis and Posterior Ophthalmic Manifestations Following the SARS-CoV-2 (COVID-19) Vaccine.

    Patel, Kishan G / Hilton, Taylor / Choi, Rene Y / Abbey, Ashkan M

    Ocular immunology and inflammation

    2022  Volume 30, Issue 5, Page(s) 1142–1148

    Abstract: Purpose: To present four cases of posterior ophthalmic manifestations associated with a temporal relationship to SARS-CoV-2 vaccination.: Methods: Retrospective case series with a review of clinical findings.: Results: Four patients presented with ...

    Abstract Purpose: To present four cases of posterior ophthalmic manifestations associated with a temporal relationship to SARS-CoV-2 vaccination.
    Methods: Retrospective case series with a review of clinical findings.
    Results: Four patients presented with various posterior ophthalmic findings including uveitis, maculopathy, and optic neuropathy. Each of their clinical courses varied in terms of ophthalmic imaging and exam findings.
    Conclusion: The coronavirus disease 2019 (COVID-19) pandemic has ushered in a new wave of challenges to healthcare, epidemiological endeavors, and widespread vaccination efforts. Novel vaccines have been developed for the SARS-CoV-2 virus, including both mRNA and viral vector-based platforms. The ocular manifestations and side effects related to the SARS-CoV-2 vaccine is not well established or understood. There may be an association between vaccination and posterior ophthalmic manifestations.
    MeSH term(s) Humans ; COVID-19 ; COVID-19 Vaccines/adverse effects ; Retrospective Studies ; RNA, Messenger ; SARS-CoV-2 ; Uveitis/chemically induced ; Uveitis/diagnosis ; Vaccination ; Viral Vaccines
    Chemical Substances COVID-19 Vaccines ; RNA, Messenger ; Viral Vaccines
    Language English
    Publishing date 2022-06-28
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1193873-0
    ISSN 1744-5078 ; 0927-3948
    ISSN (online) 1744-5078
    ISSN 0927-3948
    DOI 10.1080/09273948.2022.2079533
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: A Rare Case of Isolated Intramedullary Spinal Cord Cysticercosis.

    Vadher, Abhishek / Raval, Maharshi R / Shah, Suchi D / Patel, Kishan G / Sharma, Kamal

    Cureus

    2021  Volume 13, Issue 5, Page(s) e14864

    Abstract: Neurocysticercosis is a parasitic disease often involving the central nervous system ... ...

    Abstract Neurocysticercosis is a parasitic disease often involving the central nervous system by
    Language English
    Publishing date 2021-05-06
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.14864
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Severe Spontaneous Tilt of Scleral-Fixated Intraocular Lenses.

    Enright, Jennifer M / Purt, Boonkit / Bruck, Brent / Shah, Parth / Eton, Emily / Rezaei, Sina / Armenti, Stephen / Patel, Kishan G / Liu, James / Verkade, Angela / Hamad, Abdualrahman / Wubben, Thomas J / Sheybani, Arsham / Crandall, David / Tannen, Bradford L / Comer, Grant M / Mian, Shahzad / Nallasamy, Nambi

    American journal of ophthalmology

    2024  Volume 262, Page(s) 206–212

    Abstract: Purpose: To report and evaluate a multicenter series of 18 cases of severe, spontaneous IOL tilt involving the flanged intrascleral haptic fixation technique (FISHF).: Design: Clinical study with historical controls.: Methods: We report a cross- ... ...

    Abstract Purpose: To report and evaluate a multicenter series of 18 cases of severe, spontaneous IOL tilt involving the flanged intrascleral haptic fixation technique (FISHF).
    Design: Clinical study with historical controls.
    Methods: We report a cross-sectional study of 46 FISHF cases using the CT Lucia 602 IOL at a single academic center over a period of 24 weeks to determine the incidence of severe rotisserie-style rotational tilt. These rates were then compared with the same time-frame the prior year to help determine if this is a new phenomenon. Additional cases of severe tilt were solicited from another 4 academic centers.
    Results: Among 46 FISHF cases at a single center, 5 developed severe tilt. No clear pattern in surgical technique, ocular history, or ocular anatomy was evident in these cases compared with controls, although the involved IOLs clustered within a narrow diopter range, indicative of a batch effect. In the same 24-week interval the year before, 33 FISHF cases were performed, none of which exhibited severe rotational tilt. In our multicenter dataset, 18 cases of tilt were identified. Surgeons included fellow and early-career physicians as well as surgeons with multiple years of experience with the Yamane technique. A variety of surgical approaches for FISHF were represented. In at least 8 of the cases, haptic rotation and/or dehiscence at the optic-haptic junction were documented.
    Conclusions: The identification of haptic rotation and dehiscence intraoperatively in several cases may reflect a new stability issue involving the optic-haptic junction.
    MeSH term(s) Humans ; Sclera/surgery ; Cross-Sectional Studies ; Lenses, Intraocular ; Lens Implantation, Intraocular/methods ; Female ; Male ; Aged ; Artificial Lens Implant Migration/surgery ; Artificial Lens Implant Migration/physiopathology ; Middle Aged ; Visual Acuity/physiology ; Aged, 80 and over ; Phacoemulsification
    Language English
    Publishing date 2024-02-17
    Publishing country United States
    Document type Journal Article ; Multicenter Study ; Clinical Study
    ZDB-ID 80030-2
    ISSN 1879-1891 ; 0002-9394
    ISSN (online) 1879-1891
    ISSN 0002-9394
    DOI 10.1016/j.ajo.2024.02.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Idiopathic Intracranial Hypertension Without Papilledema With Improvement in Visual Field Defect Following Optic Nerve Sheath Fenestration: Response.

    Scofield-Kaplan, Stacy M / Patel, Kishan G / Jones, Freddie Ray / Hogan, Robert Nick

    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society

    2020  Volume 41, Issue 1, Page(s) 135–136

    Language English
    Publishing date 2020-04-30
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1189901-3
    ISSN 1536-5166 ; 1070-8022
    ISSN (online) 1536-5166
    ISSN 1070-8022
    DOI 10.1097/WNO.0000000000000969
    Database MEDical Literature Analysis and Retrieval System OnLINE

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