Article ; Online: Multitarget Potential Drug Candidates for High-Grade Gliomas Identified by Multiple Reaction Monitoring Coupled with
Omics : a journal of integrative biology
2024 Volume 28, Issue 2, Page(s) 59–75
Abstract: High-grade gliomas (HGGs) are extremely aggressive primary brain tumors with high mortality rates. Despite notable progress achieved by clinical research and biomarkers emerging from proteomics studies, efficacious drugs and therapeutic targets are ... ...
| Abstract | High-grade gliomas (HGGs) are extremely aggressive primary brain tumors with high mortality rates. Despite notable progress achieved by clinical research and biomarkers emerging from proteomics studies, efficacious drugs and therapeutic targets are limited. This study used targeted proteomics, |
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| MeSH term(s) | Humans ; Temozolomide/pharmacology ; Molecular Docking Simulation ; Drug Repositioning/methods ; Glioma/drug therapy ; Indazoles ; Pyrimidines ; Sulfonamides |
| Chemical Substances | pazopanib (7RN5DR86CK) ; Temozolomide (YF1K15M17Y) ; Indazoles ; Pyrimidines ; Sulfonamides |
| Language | English |
| Publishing date | 2024-02-06 |
| Publishing country | United States |
| Document type | Journal Article |
| ZDB-ID | 2030312-9 |
| ISSN | 1557-8100 ; 1536-2310 |
| ISSN (online) | 1557-8100 |
| ISSN | 1536-2310 |
| DOI | 10.1089/omi.2023.0256 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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