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  1. Book ; Online: Chapter Il racconto dei luoghi: indagini storico-rappresentative della facciata della chiesa di san Matteo a Scicli

    Valenti, Rita / Gatto, Simona / Paternò, Emanuela

    (diségno)

    2022  

    Series title diségno
    Keywords Semiotics / semiology ; History ; Impact of science & technology on society ; Discipline of representation, History, Semiotics, Science, Technology
    Language Italian
    Size 1 Online-Ressource
    Publisher FrancoAngeli
    Publishing place Milan
    Document type Book ; Online
    Note Italian ; English
    HBZ-ID HT030379410
    ISBN 9788835141938 ; 8835141931
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: In Reply: Safety Considerations for Neurosurgical Procedures During the COVID-19 Pandemic.

    Assietti, Roberto / Calloni, Tommaso / Paternò, Emanuela Vita Maria / Bongetta, Daniele / Gemma, Marco Fabio

    Neurosurgery

    2020  Volume 87, Issue 6, Page(s) E701–E702

    MeSH term(s) COVID-19 ; Humans ; Neurosurgery ; Neurosurgical Procedures/adverse effects ; Pandemics ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-09-04
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 135446-2
    ISSN 1524-4040 ; 0148-396X
    ISSN (online) 1524-4040
    ISSN 0148-396X
    DOI 10.1093/neuros/nyaa420
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Endoscopic full-thickness resection of a submucosal right colon lesion.

    Salerno, Raffaele / Gherardi, Giorgio / Paternò, Emanuela / Ardizzone, Sandro

    Endoscopy

    2016  Volume 48, Issue S 01, Page(s) E376–E377

    MeSH term(s) Colonic Neoplasms/surgery ; Endoscopy, Gastrointestinal/methods ; Female ; Humans ; Lymphoma, Large B-Cell, Diffuse/pathology ; Lymphoma, Large B-Cell, Diffuse/surgery ; Middle Aged
    Language English
    Publishing date 2016
    Publishing country Germany
    Document type Case Reports ; Journal Article ; Video-Audio Media
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/s-0042-120338
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: In Reply: Safety Considerations for Neurosurgical Procedures During the COVID-19 Pandemic

    Assietti, Roberto / Calloni, Tommaso / Paternò, Emanuela Vita Maria / Bongetta, Daniele / Gemma, Marco Fabio

    Neurosurgery

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #744571
    Database COVID19

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  5. Article ; Online: In Reply

    Assietti, Roberto / Calloni, Tommaso / Paternò, Emanuela Vita Maria / Bongetta, Daniele / Gemma, Marco Fabio

    Neurosurgery ; ISSN 0148-396X 1524-4040

    Safety Considerations for Neurosurgical Procedures During the COVID-19 Pandemic

    2020  

    Keywords Surgery ; Clinical Neurology ; covid19
    Language English
    Publisher Oxford University Press (OUP)
    Publishing country uk
    Document type Article ; Online
    DOI 10.1093/neuros/nyaa420
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: Endoscopic full-thickness resection of a submucosal right colon lesion

    Salerno, Raffaele / Gherardi, Giorgio / Paternò, Emanuela / Ardizzone, Sandro

    Endoscopy

    2016  Volume 48, Issue S 01, Page(s) E376–E377

    Language English
    Publishing date 2016-01-01
    Publisher © Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/s-0042-120338
    Database Thieme publisher's database

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  7. Article ; Online: The prognostic role of tumor size in early breast cancer in the era of molecular biology.

    Kasangian, Anaid Anna / Gherardi, Giorgio / Biagioli, Elena / Torri, Valter / Moretti, Anna / Bernardin, Elena / Cordovana, Andrea / Farina, Gabriella / Bramati, Annalisa / Piva, Sheila / Dazzani, Maria Chiara / Paternò, Emanuela / La Verde, Nicla Maria

    PloS one

    2017  Volume 12, Issue 12, Page(s) e0189127

    Abstract: Background: The prognosis of early breast cancer (EBC) depends on patient and tumor characteristics. The association between tumor size, the largest diameter in TNM staging, and prognosis is well recognized. According to TNM, tumors classified as T2, ... ...

    Abstract Background: The prognosis of early breast cancer (EBC) depends on patient and tumor characteristics. The association between tumor size, the largest diameter in TNM staging, and prognosis is well recognized. According to TNM, tumors classified as T2, could have very different volumes; e.g. a tumor of 2.1 cm has a volume of 4500 mm3, while a tumor of 4.9 cm has a volume of 60.000 mm3 even belonging to the same class. The aim of the study is to establish if the prognostic role of tumor size, expressed as diameter and volume, has been overshadowed by other factors.
    Methods: The primary objective is to evaluate the association between tumor dimensions and overall survival (OS) / disease free survival (DFS), in our institution from January 1st 2005 to September 30th 2013 in a surgical T1-T2 population. Volume was evaluated with the measurement of three half-diameters of the tumor (a, b and c), and calculated using the following formula: 4/3π x a x b x c.
    Results: 341 patients with T1-T2 EBC were included. 86.5% were treated with conservative surgery. 85.1% had a Luminal subtype, 9.1% were Triple negative and 7.4% were HER2 positive. Median volume was 942 mm3 (range 0.52-31.651.2). 44 patients (12.9%) relapsed and 23 patients died. With a median follow-up of 6.5 years, the univariate analysis for DFS showed an association between age, tumor size, volume, histological grading and molecular subtype. The multivariate analysis confirmed the statistically significant association only for molecular subtype (p 0.005), with a worse prognosis for Triple negative and HER2 positive subtypes compared with Luminal (HR: 2.65; 95%CI: 1.34-5.22). Likewise for OS, an association was shown by the multivariate analysis solely for molecular subtype (HER2 and Triple negative vs. Luminal. HR: 2.83; 95% CI:1.46-5.49; p 0.002).
    Conclusions: In our study, the only parameter that strongly influences survival is molecular subtype. These findings encourage clinicians to choose adjuvant treatment not based on dimensional criteria but on biological features.
    MeSH term(s) Aged ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; Female ; Humans ; Male ; Middle Aged ; Prognosis ; Survival Analysis
    Language English
    Publishing date 2017
    Publishing country United States
    Document type Journal Article
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0189127
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Predictors of CD34+ cell mobilization and collection in adult men with germ cell tumors: implications for the salvage treatment strategy.

    Necchi, Andrea / Miceli, Rosalba / Pedrazzoli, Paolo / Giannatempo, Patrizia / Secondino, Simona / Di Nicola, Massimo / Farè, Elena / Raggi, Daniele / Magni, Michele / Matteucci, Paola / Longoni, Paolo / Milanesi, Marco / Paternò, Emanuela / Ravagnani, Fernando / Arienti, Flavio / Nicolai, Nicola / Salvioni, Roberto / Carlo-Stella, Carmelo / Gianni, Alessandro M

    Clinical genitourinary cancer

    2014  Volume 12, Issue 3, Page(s) 196–202.e1

    Abstract: Background: High-dose chemotherapy with tandem or triple carboplatin and etoposide course is currently the first curative choice for relapsing GCT. The collection of an adequate amount of hematopoietic (CD34(+)) stem cells is a priority.: Patients and ...

    Abstract Background: High-dose chemotherapy with tandem or triple carboplatin and etoposide course is currently the first curative choice for relapsing GCT. The collection of an adequate amount of hematopoietic (CD34(+)) stem cells is a priority.
    Patients and methods: We analyzed data of patients who underwent HDCT at 2 referral institutions. Chemotherapy followed by myeloid growth factors was applied in all cases. Uni- and multivariable models were used to evaluate the association between 2 prespecified variables and mobilization parameters. Analyses included only the first mobilizing course of chemotherapy and mobilization failures.
    Results: A total of 116 consecutive patients underwent a mobilization attempt from December 1995 to November 2012. Mobilizing regimens included cyclophosphamide (CTX) 7 gr/m(2) (n = 39), cisplatin, etoposide, and ifosfamide (PEI) (n = 42), paclitaxel, cisplatin, and gemcitabine (TPG) (n = 11), and mixed regimens (n = 24). Thirty-seven percent were treated in first-line, 50% (n = 58) in second-line, 9.5% (n = 11) and 3.4% (n = 4) in third- and fourth-line settings, respectively. Six patients did not undergo HDCT because they were poor mobilizers, 2 in first- and second-line (1.9%), and 4 beyond the second-line (26.7%). In the multivariable model, third-line or later setting was associated with a lower CD34(+) cell peak/μL (P = .028) and a lower total CD34(+)/kg collected (P = .008). The latter was also influenced by the type of mobilizing regimen (P < .001).
    Conclusion: A decline in significant mobilization parameters was found, primarily depending on the pretreatment load. Results lend support to the role of CD34(+) cell mobilization in the therapeutic algorithm of relapsing GCT, for whom multiple HDCT courses are still an option, and potentially a cure.
    MeSH term(s) Adult ; Antigens, CD34/metabolism ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Hematopoietic Stem Cell Mobilization ; Hematopoietic Stem Cell Transplantation ; Hematopoietic Stem Cells/metabolism ; Humans ; Male ; Neoplasms, Germ Cell and Embryonal/therapy ; Salvage Therapy ; Testicular Neoplasms/therapy ; Treatment Outcome ; Young Adult
    Chemical Substances Antigens, CD34
    Language English
    Publishing date 2014-06
    Publishing country United States
    Document type Journal Article ; Multicenter Study
    ZDB-ID 2225121-2
    ISSN 1938-0682 ; 1558-7673
    ISSN (online) 1938-0682
    ISSN 1558-7673
    DOI 10.1016/j.clgc.2013.11.021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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