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  1. AU="Patrick Lam"
  2. AU="Cole, Sam Wilson"
  3. AU=Emr Scott
  4. AU="Dehal, A (Kaiser Permanente Panorama City Medical Center)"
  5. AU=Sterk P J
  6. AU="Baeza, Josue"
  7. AU="Rau, Fiona"
  8. AU="Chu, Chu"
  9. AU=Yang Yifan
  10. AU="Qu, Fa-Jun"
  11. AU="K.Staats, "
  12. AU="Gurpide Alfonso"
  13. AU="Joensen, Beinta Biskopstø"
  14. AU="Hönig, Florian"
  15. AU="Loboa, Elizabeth G"
  16. AU="Rolla, Martina"
  17. AU="Barakat, Khaled"
  18. AU="Silva-Islas, Carlos Alfredo"
  19. AU="Berman, Nathaniel"
  20. AU="G Chandana"
  21. AU="Boga, Narasimha Rao"
  22. AU="Borm, Frank J"
  23. AU="Nguyen L. Vuong"
  24. AU="Pozner, Jason N"
  25. AU="Vikash R. V. Tatayah"
  26. AU=Carneiro Flvia R.G.
  27. AU="Harrison, Tina"
  28. AU="Hanxin Lu"
  29. AU="Pinto, Bernardo I"
  30. AU=Marek Martin
  31. AU="Rachmilewitz, Eliezer"
  32. AU="Marc S Cortese"
  33. AU=Nguyen Quynh Huong

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  1. Artikel ; Online: Shoulder Arthroplasty as a Day Case

    Syed Mohammed Taif Rizvi / Benjamin Lenane / Patrick Lam / George A. C. Murrell

    Journal of Clinical Medicine, Vol 12, Iss 3886, p

    Is It Better?

    2023  Band 3886

    Abstract: Introduction : A retrospective case-controlled study was performed to evaluate the outcomes of shoulder arthroplasty performed as a day case in carefully selected patients, compared to the traditional inpatient approach. Materials and Methods : Patients ... ...

    Abstract Introduction : A retrospective case-controlled study was performed to evaluate the outcomes of shoulder arthroplasty performed as a day case in carefully selected patients, compared to the traditional inpatient approach. Materials and Methods : Patients who had total or hemiarthroplasty of the shoulder performed as a day case or inpatient procedure were recruited. The primary outcome compared rates of uneventful recovery, defined by the absence of complications or readmission to the hospital within six months of surgery, between the inpatient and outpatient groups. Secondary outcomes included examiner-determined functional and patient-determined pain scores at one, six, twelve, and twenty-four weeks post-surgery. A further assessment of patient-determined pain scores was carried out at least two years post-surgery (5.8 ± 3.2). Results : 73 patients (36 inpatients and 37 outpatients) were included in the study. Within this time frame, 25/36 inpatients (69%) had uneventful recoveries compared to 24/37 outpatients (65%) ( p = 0.17). Outpatients showed significant improvement over pre-operative baseline levels in more secondary outcomes (strength and passive range-of-motion) by six months post-operation. Outpatients also performed significantly better than inpatients in external rotation ( p < 0.05) and internal rotation ( p = 0.05) at six weeks post-surgery. Both groups showed significant improvement compared to pre-operative baselines in all patient-determined secondary outcomes except the activity level at work and sports. Inpatients, however, experienced less severe pain at rest at six weeks ( p = 0.03), significantly less frequent pain at night ( p = 0.03), and extreme pain ( p = 0.04) at 24 weeks, and less severe pain at night at 24 weeks ( p < 0.01). By a minimum of two years post-operation, inpatients were more comfortable repeating their treatment setting for future arthroplasty (16/18) compared to outpatients (7/22) ( p = 0.0002). Conclusions : At a minimum of two years of follow-up, there were no ...
    Schlagwörter shoulder arthroplasty ; ambulatory care ; day surgery ; surgical complications ; post-operative pain ; revision surgery ; Medicine ; R
    Thema/Rubrik (Code) 616
    Sprache Englisch
    Erscheinungsdatum 2023-06-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  2. Artikel ; Online: Acromion and Distal Clavicle Grafts for Arthroscopic Glenoid Reconstruction

    Jeffrey A. Zhang / Patrick Lam / Julia Beretov / George A. C. Murrell

    Journal of Clinical Medicine, Vol 12, Iss 4035, p

    2023  Band 4035

    Abstract: Background: We intended to determine if an acromion or distal clavicle bone graft could restore large glenoid defects using two novel, screw-free graft fixation techniques. Methods: Twenty-four sawbone shoulder models were divided into four groups (n = 6 ...

    Abstract Background: We intended to determine if an acromion or distal clavicle bone graft could restore large glenoid defects using two novel, screw-free graft fixation techniques. Methods: Twenty-four sawbone shoulder models were divided into four groups (n = 6 per group) according to fixation technique and bone graft: (1) modified buckle-down technique with clavicle graft, (2) modified buckle-down technique with acromion graft, (3) cross-link technique with acromion graft, (4) cross-link technique with clavicle graft. Testing was performed sequentially in (1) intact models, (2) after creation of a 30% by-width glenoid defect and (3) after repair. The shoulder joint was translated anteriorly, and glenohumeral contact pressures and load were measured to quantify the biomechanical stability. Results: Maximum contact pressures were restored to 42–56% of intact glenoid using acromion and clavicle grafts with novel fixation techniques. Acromion grafts attained higher maximum contact pressures than clavicle grafts in all groups. Peak translational forces increased by 171–368% after all repairs. Conclusions: This controlled laboratory study on sawbone models found that both the acromion and distal clavicle are suitable autologous bone graft options for treating large anterior glenoid defects, having appropriate dimensions and contours for reconstructing the glenoid arc. The modified buckle-down and cross-link techniques are two graft fixation techniques that restore stability to the shoulder joint upon repairing a large glenoid defect and are advantageous in being screw-free and simple to execute.
    Schlagwörter bony Bankart ; glenoid defect ; glenoid reconstruction ; bone graft ; biomechanics ; recurrent dislocation ; Medicine ; R
    Thema/Rubrik (Code) 610
    Sprache Englisch
    Erscheinungsdatum 2023-06-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  3. Artikel ; Online: There’s an App for That

    Jason Folt / Patrick Lam / Joseph Miller / Nikhil Goyal

    Western Journal of Emergency Medicine, Vol 22, Iss

    A Mobile Procedure Logging Application Using Quick Response Codes

    2020  Band 1

    Abstract: Emergency medicine residents are required to accurately log all procedures, yet it is estimated that many procedures are not logged. Traditional procedure logging platforms are often cumbersome and may contribute to procedures not being logged or being ... ...

    Abstract Emergency medicine residents are required to accurately log all procedures, yet it is estimated that many procedures are not logged. Traditional procedure logging platforms are often cumbersome and may contribute to procedures not being logged or being logged inaccurately. We designed a mobile procedure logging application (app) that uses quick response (QR) codes to input patient information quickly and accurately. The app integrates with our current procedure log database while maintaining information privacy standards. It scans the QR code displayed for patient identification, automatically extracting pertinent patient information. The user selects the procedure performed and the app uses data analytics to recommend logging other related procedures. A mobile procedure logging app using QR codes decreases time needed to log procedures and eliminates data entry errors. Improving the speed and convenience of procedure logging may decrease the discrepancy between performed and logged procedures. A similar app can be integrated into any residency program and may improve assessment of resident procedural competency.
    Schlagwörter Medicine ; R ; Medical emergencies. Critical care. Intensive care. First aid ; RC86-88.9
    Thema/Rubrik (Code) 005
    Sprache Englisch
    Erscheinungsdatum 2020-12-01T00:00:00Z
    Verlag eScholarship Publishing, University of California
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  4. Artikel ; Online: Ultrasound Guided Arthroscopic Removal of Calcific Tendonitis

    Syed Mohammed Taif Rizvi / David Qiu / Patrick Lam / Lisa Hackett / Judie Walton / George A. C. Murrell

    Journal of Clinical Medicine, Vol 12, Iss 3114, p

    A Minimum of 2-Year Followup

    2023  Band 3114

    Abstract: Background: We have developed a novel technique for managing rotator cuff calcific tendonitis, involving arthroscopic debridement of calcific tendonitis with localization assistance from a breast biopsy needle under ultrasound guidance. While we have ... ...

    Abstract Background: We have developed a novel technique for managing rotator cuff calcific tendonitis, involving arthroscopic debridement of calcific tendonitis with localization assistance from a breast biopsy needle under ultrasound guidance. While we have demonstrated encouraging results at six-month follow-up, the medium-term outcomes and the long-term outcomes of this technique at 2 years or beyond are unknown. The aim of this paper was to determine if this technique was successful in resolving symptoms after two years and beyond. Study Design: Retrospective Cohort Study. Methods : Patients who underwent arthroscopic debridement of calcific tendonitis with localization assistance from a breast biopsy needle under ultrasound guidance by a senior surgeon were evaluated using patient-rated pain scores and functional status with the use of the Likert scales and via examiner-rated shoulder range-of-motion and strength at the pre-operative visit, at 1, 6, 12, and 24 weeks post-operatively, and long-term at a mean of 249 weeks after surgery. Results: At a mean follow-up period of 4.8 years (range, 2–10 years), 31 patients (33 shoulders) experienced significant improvement in the severity of pain at rest, with overhead activities, and during sleep compared to their pre-operative presentation ( p < 0.001). The patient experienced less frequent pain during activities and sleep, and a decreased frequency of extreme pain ( p < 0.001). Passive range of abduction ( p = 0.003), forward flexion ( p < 0.001), and supraspinatus strength ( p = 0.018) improved compared to the presurgical presentation. Out of 27 patients, 24 patients (89%) had complete resolution of calcific tendonitis, and 26 patients (96%) had an intact rotator cuff. Conclusion: Arthroscopic debridement of calcific tendonitis with localization assistance from a breast biopsy needle under ultrasound guidance was very effective. Patients had significant pain relief, improved range of motion, and a reduction in stiffness at a mean post-operative period of 4.8 ...
    Schlagwörter calcific tendonitis ; ultrasound-guided removal ; localization ; biopsy needle ; pain ; stiffness ; Medicine ; R
    Thema/Rubrik (Code) 616
    Sprache Englisch
    Erscheinungsdatum 2023-04-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  5. Artikel ; Online: Prevalence of simian malaria parasites in macaques of Singapore.

    Meizhi Irene Li / Diyar Mailepessov / Indra Vythilingam / Vernon Lee / Patrick Lam / Lee Ching Ng / Cheong Huat Tan

    PLoS Neglected Tropical Diseases, Vol 15, Iss 1, p e

    2021  Band 0009110

    Abstract: Plasmodium knowlesi is a simian malaria parasite currently recognized as the fifth causative agent of human malaria. Recently, naturally acquired P. cynomolgi infection in humans was also detected in Southeast Asia. The main reservoir of both parasites ... ...

    Abstract Plasmodium knowlesi is a simian malaria parasite currently recognized as the fifth causative agent of human malaria. Recently, naturally acquired P. cynomolgi infection in humans was also detected in Southeast Asia. The main reservoir of both parasites is the long-tailed and pig-tailed macaques, which are indigenous in this region. Due to increased urbanization and changes in land use, there has been greater proximity and interaction between the long-tailed macaques and the general population in Singapore. As such, this study aims to determine the prevalence of simian malaria parasites in local macaques to assess the risk of zoonosis to the general human population. Screening for the presence of malaria parasites was conducted on blood samples from 660 peridomestic macaques collected between Jan 2008 and Mar 2017, and 379 wild macaques collected between Mar 2009 and Mar 2017, using a Pan-Plasmodium-genus specific PCR. Positive samples were then screened using a simian Plasmodium species-specific nested PCR assay to identify the species of parasites (P. knowlesi, P. coatneyi, P. fieldi, P. cynomolgi, and P. inui) present. All the peridomestic macaques sampled were tested negative for malaria, while 80.5% of the 379 wild macaques were infected. All five simian Plasmodium species were detected; P. cynomolgi being the most prevalent (71.5%), followed by P. knowlesi (47.5%), P. inui (42.0%), P. fieldi (32.5%), and P. coatneyi (28.5%). Co-infection with multiple species of Plasmodium parasites was also observed. The study revealed that Singapore's wild long-tailed macaques are natural hosts of the five simian malaria parasite species, while no malaria was detected in all peridomestic macaques tested. Therefore, the risk of simian malaria transmission to the general human population is concluded to be low. However, this can be better demonstrated with the incrimination of the vectors of simian malaria parasites in Singapore.
    Schlagwörter Arctic medicine. Tropical medicine ; RC955-962 ; Public aspects of medicine ; RA1-1270
    Thema/Rubrik (Code) 572
    Sprache Englisch
    Erscheinungsdatum 2021-01-01T00:00:00Z
    Verlag Public Library of Science (PLoS)
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  6. Artikel ; Online: Social Video Advertisement Replacement and its Evaluation in Convolutional Neural Networks

    Cheng Yang / Xiang Yu / Arun Kumar / G.G. Md. Nawaz Ali / Peter Han Joo Chong / Patrick Lam

    ELCVIA Electronic Letters on Computer Vision and Image Analysis, Vol 20, Iss

    2021  Band 1

    Abstract: This paper introduces a method to use deep convolutional neural networks (CNNs) to automatically replace advertisement (AD) photo on social (or self-media) videos and provides the suitable evaluation method to compare different CNNs. An AD photo can ... ...

    Abstract This paper introduces a method to use deep convolutional neural networks (CNNs) to automatically replace advertisement (AD) photo on social (or self-media) videos and provides the suitable evaluation method to compare different CNNs. An AD photo can replace a picture inside a video. However, if a human being occludes the replaced picture in the original video, the newly pasted AD photo will block the human occluded part. The deep learning algorithm is implemented to segment the human being from the video. The segmented human pixels are then pasted back to the occluded area, so that the AD photo replacement becomes natural and perfect appearance in the video. This process requires the predicted occlusion edge to be closed to the ground truth occlusion edge, so that the AD photo can be occluded naturally. Therefore, this research introduces a curve fitting method to measure the predicted occlusion edge’s error. By using this method, three CNN methods are applied and compared for the AD replacement. They are mask of regions convolutional neural network (Mask RCNN), a recurrent network for video object segmentation (ROVS) and DeeplabV3. The experimental results show the comparative segmentation accuracy of the different models and DeeplabV3 shows the best performance.
    Schlagwörter Deep Learning ; Image Processing ; Image Segmentation ; Video Advertisement Replacement ; Computer engineering. Computer hardware ; TK7885-7895 ; Electronic computers. Computer science ; QA75.5-76.95
    Thema/Rubrik (Code) 004
    Sprache Englisch
    Erscheinungsdatum 2021-05-01T00:00:00Z
    Verlag Computer Vision Center Press
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  7. Artikel ; Online: Survey of rodent-borne pathogens in Singapore reveals the circulation of Leptospira spp., Seoul hantavirus, and Rickettsia typhi

    Jane Griffiths / Hui Ling Yeo / Grace Yap / Diyar Mailepessov / Patrik Johansson / Hwee Teng Low / Chern-Chiang Siew / Patrick Lam / Lee Ching Ng

    Scientific Reports, Vol 12, Iss 1, Pp 1-

    2022  Band 14

    Abstract: Abstract Rodents living alongside humans increases the probability of encounter and also the transmission of rodent-borne diseases. Singapore’s cosmopolitan urban landscape provides a perfect setting to study the prevalence of four rodent-borne pathogens: ...

    Abstract Abstract Rodents living alongside humans increases the probability of encounter and also the transmission of rodent-borne diseases. Singapore’s cosmopolitan urban landscape provides a perfect setting to study the prevalence of four rodent-borne pathogens: Seoul hantavirus (SEOV), Leptospira species, Rickettsia typhi and Yersinia pestis, and identify the potential risk factors which may influence rodent density and transmission of rodent-borne diseases. A total of 1143 rodents were trapped from 10 unique landscape structures throughout Singapore. Real-time quantitative Polymerase Chain Reactions were used to detect pathogenic and intermediate Leptospira spp. and Yersinia pestis, whereas the seroprevalence of SEOV and R. typhi were analysed by Enzyme-Linked Immunosorbent Assay and Immunofluorescence Assay respectively. Multivariable logistic regression analysis was used to evaluate the association between prevalence of infection in rodent reservoirs and risk factors. Most of the rodents were caught in public residential developments (62.2%). Among the tested rodents, 42.4% were infected with Leptospira spp., while 35.5% and 32.2% were seropositive for SEOV and R. typhi respectively, whereas Yersinia pestis was not detected. Furthermore, risk factors including habitat, species, gender, and weight of rodents, influenced prevalence of infection to a varying extent. This study highlights the presence of Leptospira spp., SEOV and R. typhi in Singapore’s rodent population, suggesting the need for effective rodent management and sanitation strategies to prevent further circulation and transmission to humans.
    Schlagwörter Medicine ; R ; Science ; Q
    Sprache Englisch
    Erscheinungsdatum 2022-02-01T00:00:00Z
    Verlag Nature Portfolio
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  8. Artikel ; Online: A radiolabeled drug tracing method to study neurotrophin-3 retention and distribution in the cochlea after nano-based local delivery

    Patrick Lam / Niliksha Gunewardene / Yutian Ma / Frank Caruso / Trung Nguyen / Brianna Flynn / Andrew K. Wise / Rachael T. Richardson

    MethodsX, Vol 7, Iss , Pp 101078- (2020)

    2020  

    Abstract: Hearing loss is the most common sensory deficit worldwide with no approved therapeutics for treatment. Local neurotrophin delivery into the cochlea has shown great potential in protecting and repairing the sensory cells important for hearing. However, ... ...

    Abstract Hearing loss is the most common sensory deficit worldwide with no approved therapeutics for treatment. Local neurotrophin delivery into the cochlea has shown great potential in protecting and repairing the sensory cells important for hearing. However, delivery of these factors into the inner ear at therapeutic levels over a sustained period of time has remained a challenge restricting clinical translation. We have developed a method to test the pharmacokinetics of neurotrophin released from porous silica particles called ‘supraparticles’ that can provide sustained release of neurotrophins to the inner ear. • This report describes a radiolabeling method to examine neurotrophin retention and distribution in the cochlea. The neurotrophin was labeled with a radioactive tracer (iodine 125: 125I) and delivered into the cochlea via the supraparticle system. • Gamma counts reveal drug levels and clearance in the intact cochlea, as well as accumulation in off-target organs (safety test). Autoradiography analyses using film and emulsion permit quantification and visualization of drug distribution at the cellular level. The method has a detection limit of 0.8 pg of radiolabeled neurotrophin-3 in cochlear sections exposed to film. • The tracer 125I with a half-life of 59.4 days can be used to label other drugs/substances with a tyrosine residue and therefore be broadly applicable for long-term pharmacokinetic studies in other systems.
    Schlagwörter Drug delivery ; Nanoparticles ; Neurotrophins ; Hearing loss ; Inner ear ; Cochlea ; Science ; Q
    Sprache Englisch
    Erscheinungsdatum 2020-01-01T00:00:00Z
    Verlag Elsevier
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  9. Artikel ; Online: Channel Allocation Method for Multi-radio Wireless Mesh Networks based on a Genetic Algorithm

    Li Yingxiong / Henry C. B. Chan / Patrick Lam / Peter. H. J. Chong

    Lecture Notes in Engineering and Computer Science, Vol 2222, Iss 1, Pp 521-

    2016  Band 526

    Schlagwörter Electronic computers. Computer science ; QA75.5-76.95 ; Instruments and machines ; QA71-90 ; Mathematics ; QA1-939 ; Science ; Q
    Sprache Englisch
    Erscheinungsdatum 2016-03-01T00:00:00Z
    Verlag Newswood and International Association of Engineers
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  10. Artikel ; Online: Approach to the Evaluation and Management of Wide Complex Tachycardias.

    Patrick Lam / Samir Saba

    Indian Pacing and Electrophysiology Journal, Vol 2, Iss 4, Pp 120-

    2002  Band 126

    Abstract: Wide complex tachycardia (WCT) refers to a cardiac rhythm of more than 100 beats per minute with a QRS duration of 120 ms or more on the surface electrocardiogram (ECG). It often presents a diagnostic dilemma for the physician particularly in determining ...

    Abstract Wide complex tachycardia (WCT) refers to a cardiac rhythm of more than 100 beats per minute with a QRS duration of 120 ms or more on the surface electrocardiogram (ECG). It often presents a diagnostic dilemma for the physician particularly in determining its site of origin, which can be ventricular or supraventricular. In one series, only 32% of clinicians correctly diagnosed ventricular tachycardia (VT) in patients who presented with WCT1. Prompt diagnosis of the etiology of WCT is, however, essential since immediate care is frequently required. Diagnostic and therapeutic errors can produce poor outcome especially when ventricular tachycardia is not recognized.2,3 WCT that is grossly irregular typically represents atrial fibrillation with aberrant conduction or preexcitation. If its rate exceeds 200 beats per minute, the likelihood of atrial fibrillation with conduction over an accessory pathway should be entertained. In this article, we will discuss the approach to the evaluation and management of regular WCT.
    Schlagwörter wide QRS tachycardia ; differential diagnosis ; Diseases of the circulatory (Cardiovascular) system ; RC666-701 ; Specialties of internal medicine ; RC581-951 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Cardiovascular ; DOAJ:Medicine (General) ; DOAJ:Health Sciences ; Physiology ; QP1-981 ; Science ; Q ; DOAJ:Physiology ; DOAJ:Biology ; DOAJ:Biology and Life Sciences
    Sprache Englisch
    Erscheinungsdatum 2002-10-01T00:00:00Z
    Verlag Elsevier
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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