LIVIVO - Das Suchportal für Lebenswissenschaften

switch to English language
Erweiterte Suche

Ihre letzten Suchen

  1. AU="Patruno, A."
  2. AU="Amrutha Nisthul, A"
  3. AU="Fischer, K." AU="Fischer, K."
  4. AU="Pushap Raj"
  5. AU="Martin-Vila, Alicia"
  6. AU="Houska, Jiri"
  7. AU="Uwer, Lionel"
  8. AU="Yoo, Heejin"

Suchergebnis

Treffer 1 - 10 von insgesamt 125

Suchoptionen

  1. Artikel ; Online: Are Gravitational Waves Spinning Down PSR J1023+0038?

    Haskell, B / Patruno, A

    Physical review letters

    2017  Band 119, Heft 16, Seite(n) 161103

    Abstract: The pulsar J1023+0038 rotates with a frequency ν≈592  Hz and has been observed to transition between a radio state, during which it is visible as a millisecond radio pulsar, and a low-mass x-ray binary (LMXB) state, during which accretion powered x-ray ... ...

    Abstract The pulsar J1023+0038 rotates with a frequency ν≈592  Hz and has been observed to transition between a radio state, during which it is visible as a millisecond radio pulsar, and a low-mass x-ray binary (LMXB) state, during which accretion powered x-ray pulsations are visible. Timing during the two phases reveals that during the LMXB phase the neutron star is spinning down at a rate of ν[over ˙]≈-3×10^{-15}  Hz/s, which is approximately 27% faster than the rate measured during the radio phase, ν[over ˙]≈-2.4×10^{-15}  Hz/s, and is at odds with the predictions of accretion models. We suggest that the increase in spin-down rate is compatible with gravitational wave emission, particularly with the creation of a "mountain" during the accretion phase. We show that asymmetries in pycnonuclear reaction rates in the crust can lead to a large enough mass quadrupole to explain the observed spin-down rate, which thus far has no other self-consistent explanation. We also suggest two observational tests of this scenario, involving radio timing at the onset of the next millisecond radio pulsar phase, when the mountain should dissipate, and accurate timing during the next LMXB phase to track the increase in torque as the mountain builds up. Another possibility is that an unstable r mode with an amplitude α≈5×10^{-8} may be present in the system.
    Sprache Englisch
    Erscheinungsdatum 2017-10-20
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.119.161103
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  2. Artikel ; Online: Cigarette smoke is associated with up-regulation of inducible NOS and COX-2 protein expression and activity in granulosa cells of women undergoing in vitro fertilization.

    Budani, M C / Gallorini, M / Elsallabi, O / Pino, V / La Fratta, I / Pesce, M / Ricciotti, E / Tiboni, G M / Patruno, A

    Reproductive toxicology (Elmsford, N.Y.)

    2022  Band 113, Seite(n) 128–135

    Abstract: Cigarette smoke exposure represents a well-established ovotoxic exogenous stress, but the molecular mechanisms underlying of this effect are still unclear. Cigarette smoke upregulates inflammatory genes in the female reproductive organs, therefore an ... ...

    Abstract Cigarette smoke exposure represents a well-established ovotoxic exogenous stress, but the molecular mechanisms underlying of this effect are still unclear. Cigarette smoke upregulates inflammatory genes in the female reproductive organs, therefore an abnormal inflammation response may contribute to the impairment of female fertility. In this study we investigated for the first time the effect of cigarette smoke exposure on NOS and COX expression and activity and on their transcription factors (CREB and NF-kB) in human GCs and on the release of NO and PGE
    Mesh-Begriff(e) Cigarette Smoking ; Cyclooxygenase 2/genetics ; Dinoprostone ; Female ; Fertilization in Vitro ; Granulosa Cells ; Humans ; NF-kappa B ; Nitric Oxide Synthase ; Nicotiana ; Up-Regulation
    Chemische Substanzen NF-kappa B ; Nitric Oxide Synthase (EC 1.14.13.39) ; Cyclooxygenase 2 (EC 1.14.99.1) ; Dinoprostone (K7Q1JQR04M)
    Sprache Englisch
    Erscheinungsdatum 2022-08-29
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 639342-1
    ISSN 1873-1708 ; 0890-6238
    ISSN (online) 1873-1708
    ISSN 0890-6238
    DOI 10.1016/j.reprotox.2022.08.013
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  3. Artikel ; Online: Probing neutron star physics using accreting neutron stars

    Patruno A.

    EPJ Web of Conferences, Vol 7, p

    2010  Band 03005

    Abstract: We give an obervational overview of the accreting neutron stars systems as probes of neutron star physics. In particular we focus on the results obtained from the periodic timing of accreting millisecond X-ray pulsars in outburst and from the measurement ...

    Abstract We give an obervational overview of the accreting neutron stars systems as probes of neutron star physics. In particular we focus on the results obtained from the periodic timing of accreting millisecond X-ray pulsars in outburst and from the measurement of X-ray spectra of accreting neutron stars during quiescence. In the first part of this overview we show that the X-ray pulses are contaminated by a large amount of noise of uncertain origin, and that all these neutron stars do not show evidence of spin variations during the outburst. We present also some recent developments on the presence of intermittency in three accreting millisecond X-ray pulsars and investigate the reason why only a small number of accreting neutron stars show X-ray pulsations and why none of these pulsars shows sub-millisecond spin periods. In the second part of the overview we introduce the observational technique that allows the study of neutron star cooling in accreting systems as probes of neutron star internal composition and equation of state. We explain the phenomenon of the deep crustal heating and present some recent developments on several quasi persistent X-ray sources where a cooling neutron star has been observed.
    Schlagwörter Physics ; QC1-999 ; Science ; Q ; DOAJ:Physics (General) ; DOAJ:Physics and Astronomy
    Thema/Rubrik (Code) 520
    Sprache Englisch
    Erscheinungsdatum 2010-10-01T00:00:00Z
    Verlag EDP Sciences
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Zusatzmaterialien

    Kategorien

  4. Artikel ; Online: Fisetin as a Senotherapeutic Agent: Biopharmaceutical Properties and Crosstalk between Cell Senescence and Neuroprotection.

    Elsallabi, Osama / Patruno, Antonia / Pesce, Mirko / Cataldi, Amelia / Carradori, Simone / Gallorini, Marialucia

    Molecules (Basel, Switzerland)

    2022  Band 27, Heft 3

    Abstract: Like other organs, brain functions diminish with age. Furthermore, for a variety of neurological disorders-including Alzheimer's disease-age is one of the higher-risk factors. Since in many Western countries the average age is increasing, determining ... ...

    Abstract Like other organs, brain functions diminish with age. Furthermore, for a variety of neurological disorders-including Alzheimer's disease-age is one of the higher-risk factors. Since in many Western countries the average age is increasing, determining approaches for decreasing the effects of aging on brain function is taking on a new urgency. Neuroinflammation and oxidative stress are two convoluted key factors in brain aging and chronic neurodegenerative diseases. The diverseness of factors, causing an age-related decrease in brain functions, requires identifying small molecules that have multiple biological activities that can affect all these factors. One great source of these small molecules is related to polyphenolic flavonoids. Recently, 3,3',4',7-tetrahydroxyflavone (fisetin) has been reported as a potent senotherapeutic capable of extending lifespan by reducing peroxidation levels and enhancing antioxidant cell responses. The neuroprotective effects of fisetin have been shown in several in vitro and in vivo models of neurological disorders due to its actions on multiple pathways associated with different neurological disorders. The present work aims to collect the most recent achievements related to the antioxidant and neuroprotective effects of fisetin. Moreover, in silico pharmacokinetics, pharmacodynamics, and toxicity of fisetin are also comprehensively described along with emerging novel drug delivery strategies for the amelioration of this flavonol bioavailability and chemical stability.
    Mesh-Begriff(e) Animals ; Antioxidants/pharmacology ; Cellular Senescence ; Flavonols/pharmacology ; Humans ; Nervous System Diseases ; Neuroprotective Agents/pharmacology
    Chemische Substanzen Antioxidants ; Flavonols ; Neuroprotective Agents ; fisetin (OO2ABO9578)
    Sprache Englisch
    Erscheinungsdatum 2022-01-23
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules27030738
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  5. Artikel ; Online: Microbiota in ICU, not only a gut problem.

    Alagna, L / Bandera, A / Patruno, A / Muscatello, A / Citerio, G / Gori, A

    Intensive care medicine

    2019  Band 45, Heft 5, Seite(n) 733–737

    Mesh-Begriff(e) Gastrointestinal Microbiome ; Hospitalization ; Humans ; Intensive Care Units ; Microbiota
    Sprache Englisch
    Erscheinungsdatum 2019-01-22
    Erscheinungsland United States
    Dokumenttyp Letter ; Comment
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-018-05516-7
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  6. Artikel ; Online: Ozone effect on the inflammatory and proteomic profile of human macrophages and airway epithelial cells.

    Milillo, C / Falcone, L / Di Carlo, P / Aruffo, E / Del Boccio, P / Cufaro, M C / Patruno, A / Pesce, M / Ballerini, P

    Respiratory physiology & neurobiology

    2022  Band 307, Seite(n) 103979

    Abstract: ... Ozone ( ... ...

    Abstract Ozone (O
    Mesh-Begriff(e) Humans ; Ozone/toxicity ; Ozone/metabolism ; Interleukin-8 ; Tumor Necrosis Factor-alpha/metabolism ; Reactive Oxygen Species/metabolism ; Proteomics ; Epithelial Cells/metabolism ; Lung/metabolism ; Macrophages/metabolism
    Chemische Substanzen Ozone (66H7ZZK23N) ; Interleukin-8 ; Tumor Necrosis Factor-alpha ; Reactive Oxygen Species
    Sprache Englisch
    Erscheinungsdatum 2022-10-13
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2077867-3
    ISSN 1878-1519 ; 1569-9048
    ISSN (online) 1878-1519
    ISSN 1569-9048
    DOI 10.1016/j.resp.2022.103979
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  7. Artikel ; Online: Polystyrene nanoplastics mediate oxidative stress, senescence, and apoptosis in a human alveolar epithelial cell line.

    Milillo, Cristina / Aruffo, Eleonora / Di Carlo, Piero / Patruno, Antonia / Gatta, Marco / Bruno, Annalisa / Dovizio, Melania / Marinelli, Lisa / Dimmito, Marilisa Pia / Di Giacomo, Viviana / Paolini, Cecilia / Pesce, Mirko / Ballerini, Patrizia

    Frontiers in public health

    2024  Band 12, Seite(n) 1385387

    Abstract: Background: Nanoplastics, an emerging form of pollution, are easily consumed by organisms and pose a significant threat to biological functions due to their size, expansive surface area, and potent ability to penetrate biological systems. Recent ... ...

    Abstract Background: Nanoplastics, an emerging form of pollution, are easily consumed by organisms and pose a significant threat to biological functions due to their size, expansive surface area, and potent ability to penetrate biological systems. Recent findings indicate an increasing presence of airborne nanoplastics in atmospheric samples, such as polystyrene (PS), raising concerns about potential risks to the human respiratory system.
    Methods: This study investigates the impact of 800 nm diameter-PS nanoparticles (PS-NPs) on A549, a human lung adenocarcinoma cell line, examining cell viability, redox balance, senescence, apoptosis, and internalization. We also analyzed the expression of hallmark genes of these processes.
    Results: We demonstrated that PS-NPs of 800 nm in diameter significantly affected cell viability, inducing oxidative stress, cellular senescence, and apoptosis. PS-NPs also penetrated the cytoplasm of A549 cells. These nanoparticles triggered the transcription of genes comprised in the antioxidant network [SOD1 (protein name: superoxide dismutase 1, soluble), SOD2 (protein name: superoxide dismutase 2, mitochondrial), CAT (protein name: catalase), Gpx1 (protein name: glutathione peroxidase 1), and HMOX1 (protein name: heme oxygenase 1)], senescence-associated secretory phenotype [Cdkn1a (protein name: cyclin-dependent kinase inhibitor 1A), IL1A (protein name: interleukin 1 alpha), IL1B (protein name: interleukin 1 beta), IL6 (protein name: interleukin 6), and CXCL8 (protein name: C-X-C motif chemokine ligand 8)], and others involved in the apoptosis modulation [BAX (protein name: Bcl2 associated X, apoptosis regulator), CASP3 (protein name: caspase 3), and BCL2 (protein name: Bcl2, apoptosis regulator)].
    Conclusion: Collectively, this investigation underscores the importance of concentration (dose-dependent effect) and exposure duration as pivotal factors in assessing the toxic effects of PS-NPs on alveolar epithelial cells. Greater attention needs to be directed toward comprehending the risks of cancer development associated with air pollution and the ensuing environmental toxicological impacts on humans and other terrestrial mammals.
    Mesh-Begriff(e) Humans ; Oxidative Stress/drug effects ; Apoptosis/drug effects ; Polystyrenes/toxicity ; Cellular Senescence/drug effects ; A549 Cells ; Nanoparticles ; Alveolar Epithelial Cells/metabolism ; Alveolar Epithelial Cells/drug effects ; Cell Survival/drug effects ; Microplastics/toxicity
    Chemische Substanzen Polystyrenes ; Microplastics
    Sprache Englisch
    Erscheinungsdatum 2024-05-10
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2024.1385387
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  8. Artikel ; Online: A Review of Plant Extracts and Plant-Derived Natural Compounds in the Prevention/Treatment of Neonatal Hypoxic-Ischemic Brain Injury.

    Mohsenpour, Hadi / Pesce, Mirko / Patruno, Antonia / Bahrami, Azam / Pour, Pardis Mohammadi / Farzaei, Mohammad Hosein

    International journal of molecular sciences

    2021  Band 22, Heft 2

    Abstract: Neonatal hypoxic-ischemic (HI) brain injury is one of the major drawbacks of mortality and causes significant short/long-term neurological dysfunction in newborn infants worldwide. To date, due to multifunctional complex mechanisms of brain injury, there ...

    Abstract Neonatal hypoxic-ischemic (HI) brain injury is one of the major drawbacks of mortality and causes significant short/long-term neurological dysfunction in newborn infants worldwide. To date, due to multifunctional complex mechanisms of brain injury, there is no well-established effective strategy to completely provide neuroprotection. Although therapeutic hypothermia is the proven treatment for hypoxic-ischemic encephalopathy (HIE), it does not completely chang outcomes in severe forms of HIE. Therefore, there is a critical need for reviewing the effective therapeutic strategies to explore the protective agents and methods. In recent years, it is widely believed that there are neuroprotective possibilities of natural compounds extracted from plants against HIE. These natural agents with the anti-inflammatory, anti-oxidative, anti-apoptotic, and neurofunctional regulatory properties exhibit preventive or therapeutic effects against experimental neonatal HI brain damage. In this study, it was aimed to review the literature in scientific databases that investigate the neuroprotective effects of plant extracts/plant-derived compounds in experimental animal models of neonatal HI brain damage and their possible underlying molecular mechanisms of action.
    Mesh-Begriff(e) Animals ; Animals, Newborn ; Apoptosis ; Biological Products/therapeutic use ; Brain Diseases/metabolism ; Brain Injuries/drug therapy ; Cytokines/metabolism ; Disease Models, Animal ; Free Radicals ; Humans ; Hypothermia, Induced/methods ; Hypoxia-Ischemia, Brain/drug therapy ; Inflammation ; Mice ; Neurons/metabolism ; Neuroprotective Agents/therapeutic use ; Oxidative Stress ; Plant Extracts/therapeutic use ; Polyphenols/chemistry ; Rats ; Swine
    Chemische Substanzen Biological Products ; Cytokines ; Free Radicals ; Neuroprotective Agents ; Plant Extracts ; Polyphenols
    Sprache Englisch
    Erscheinungsdatum 2021-01-15
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms22020833
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  9. Artikel ; Online: Irisin and Autophagy: First Update.

    Pesce, Mirko / Ballerini, Patrizia / Paolucci, Teresa / Puca, Iris / Farzaei, Mohammad Hosein / Patruno, Antonia

    International journal of molecular sciences

    2020  Band 21, Heft 20

    Abstract: Aging and sedentary life style are considered independent risk factors for many disorders. Under these conditions, accumulation of dysfunctional and damaged cellular proteins and organelles occurs, resulting in a cellular degeneration and cell death. ... ...

    Abstract Aging and sedentary life style are considered independent risk factors for many disorders. Under these conditions, accumulation of dysfunctional and damaged cellular proteins and organelles occurs, resulting in a cellular degeneration and cell death. Autophagy is a conserved recycling pathway responsible for the degradation, then turnover of cellular proteins and organelles. This process is a part of the molecular underpinnings by which exercise promotes healthy aging and mitigate age-related pathologies. Irisin is a myokine released during physical activity and acts as a link between muscles and other tissues and organs. Its main beneficial function is the change of subcutaneous and visceral adipose tissue into brown adipose tissue, with a consequential increase in thermogenesis. Irisin modulates metabolic processes, acting on glucose homeostasis, reduces systemic inflammation, maintains the balance between resorption and bone formation, and regulates the functioning of the nervous system. Recently, some of its pleiotropic and favorable properties have been attributed to autophagy induction, posing irisin as an important regulator of autophagy by exercise. This review article proposes to bring together for the first time the "state of the art" knowledge regarding the effects of irisin and autophagy. Furthermore, treatments on relation between exercise/myokines and autophagy have been also achieved.
    Mesh-Begriff(e) Animals ; Autophagy ; Exercise ; Fibronectins/genetics ; Fibronectins/metabolism ; Humans ; Muscle, Skeletal/metabolism ; Muscle, Skeletal/physiology ; Signal Transduction
    Chemische Substanzen FNDC5 protein, human ; Fibronectins
    Sprache Englisch
    Erscheinungsdatum 2020-10-14
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms21207587
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  10. Artikel ; Online: Short ELF-EMF Exposure Targets SIRT1/Nrf2/HO-1 Signaling in THP-1 Cells.

    Patruno, Antonia / Costantini, Erica / Ferrone, Alessio / Pesce, Mirko / Diomede, Francesca / Trubiani, Oriana / Reale, Marcella

    International journal of molecular sciences

    2020  Band 21, Heft 19

    Abstract: Extremely low frequency electromagnetic fields (ELF-EMFs) have been known to modulate inflammatory responses by targeting signal transduction pathways and influencing cellular redox balance through the generation of oxidants and antioxidants. Here, we ... ...

    Abstract Extremely low frequency electromagnetic fields (ELF-EMFs) have been known to modulate inflammatory responses by targeting signal transduction pathways and influencing cellular redox balance through the generation of oxidants and antioxidants. Here, we studied the molecular mechanism underlying the anti-oxidative effect of ELF-EMF in THP-1 cells, particularly with respect to antioxidant enzymes, such as heme oxygenase-1 (HO-1), regulated transcriptionally through nuclear factor E2-related factor 2 (Nrf2) activation. Cells treated with lipopolysaccharides (LPS) were exposed to a 50 Hz, 1 mT extremely low frequency electromagnetic fields for 1 h, 6 h and, 24 h. Our results indicate that ELF-EMF induced HO-1 mRNA and protein expression in LPS-treated THP-1 cells, with peak expression at 6 h, accompanied with a concomitant migration to the nucleus of a truncated HO-1 protein form. The immunostaining analysis further verified a nuclear enrichment of HO-1. Moreover, ELF-EMF inhibited the protein expressions of the sirtuin1 (SIRT1) and nuclear factor kappa B (NF-kB) pathways, confirming their anti-inflammatory/antioxidative role. Pretreatment with LY294002 (Akt inhibitor) and PD980559 (ERK inhibitor) inhibited LPS-induced Nrf2 nuclear translocation and HO-1 protein expression in ELF-EMF-exposed cells. Taken together, our results suggest that short ELF-EMF exposure exerts a protective role in THP-1 cells treated with an inflammatory/oxidative insult such as LPS, via the regulation of Nrf-2/HO-1 and SIRT1 /NF-kB pathways associated with intracellular glutathione (GSH) accumulation.
    Mesh-Begriff(e) Cell Line ; Cell Movement/radiation effects ; Chromones/pharmacology ; Electromagnetic Fields ; Extracellular Signal-Regulated MAP Kinases/antagonists & inhibitors ; Gene Expression Regulation/radiation effects ; Glutathione/genetics ; Glutathione/metabolism ; Heme Oxygenase-1/genetics ; Humans ; Inflammation/chemically induced ; Inflammation/genetics ; Inflammation/pathology ; Inflammation/therapy ; Lipopolysaccharides/toxicity ; Morpholines/pharmacology ; NF-E2-Related Factor 2/genetics ; Organic Chemicals/pharmacology ; Oxidative Stress/radiation effects ; Proto-Oncogene Proteins c-akt/antagonists & inhibitors ; Signal Transduction/radiation effects ; Sirtuin 1/genetics
    Chemische Substanzen Chromones ; Lipopolysaccharides ; Morpholines ; NF-E2-Related Factor 2 ; NFE2L2 protein, human ; Organic Chemicals ; PD 98058 ; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (31M2U1DVID) ; HMOX1 protein, human (EC 1.14.14.18) ; Heme Oxygenase-1 (EC 1.14.14.18) ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1) ; Extracellular Signal-Regulated MAP Kinases (EC 2.7.11.24) ; SIRT1 protein, human (EC 3.5.1.-) ; Sirtuin 1 (EC 3.5.1.-) ; Glutathione (GAN16C9B8O)
    Sprache Englisch
    Erscheinungsdatum 2020-10-02
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms21197284
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

Zum Seitenanfang