Article ; Online: Neutron-encoded diubiquitins to profile linkage selectivity of deubiquitinating enzymes
Nature Communications, Vol 14, Iss 1, Pp 1-
2023 Volume 14
Abstract: Most insights into deubiquitinase (DUB) substrate specificity originate from studies with isolated di-ubiquitins (diUb), but in cells diUbs with different linkage types coexist. Here, the authors develop a mass spectrometric DUB activity assay that can ... ...
Abstract | Most insights into deubiquitinase (DUB) substrate specificity originate from studies with isolated di-ubiquitins (diUb), but in cells diUbs with different linkage types coexist. Here, the authors develop a mass spectrometric DUB activity assay that can probe all diUbs simultaneously under substrate competition conditions. |
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Keywords | Science ; Q |
Language | English |
Publishing date | 2023-03-01T00:00:00Z |
Publisher | Nature Portfolio |
Document type | Article ; Online |
Database | BASE - Bielefeld Academic Search Engine (life sciences selection) |
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