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  1. Article ; Online: Interactive Patient Safety and Quality Improvement capstone during transition-to-residency program

    Catherine Chen / Kristen M. Coppola / Paul Weber / Payal Parikh

    BMC Medical Education, Vol 23, Iss 1, Pp 1-

    virtual and in-person focused workshop for EPA 13

    2023  Volume 6

    Abstract: Abstract Identifying systems failures and contributing to a safety culture is the Association of American Colleges (AAMC’s) thirteenth Entrustable Professional Activity (EPA). While most curricula teach Patient Safety (PS) and Quality Improvement (QI) ... ...

    Abstract Abstract Identifying systems failures and contributing to a safety culture is the Association of American Colleges (AAMC’s) thirteenth Entrustable Professional Activity (EPA). While most curricula teach Patient Safety (PS) and Quality Improvement (QI) principles, student participation in live QI/PS activities remains limited. This workshop enabled late Clerkship phase students to apply these Health Systems Science (HSS) principles to real adverse patient event cases through team-based simulation. This 3-h capstone included both a didactic review of QI, PS, and TeamSTEPPS® tools and an experiential component where student-led interactive small group discussions were augmented by resident and faculty preceptors. Collaboratively, students composed an adverse patient event report, conducted a Root Cause Analysis (RCA) during role-play, and proposed error prevention ideas after identifying systems problems. In April 2020, the in-person workshop became fully virtual due to the COVID-19 pandemic. A statistically significant increase in ability to identify Serious Safety Events, Escalation Chain of Command, and define a Plan-Do-Study-Act (PDSA) cycle was observed. Comfort with RCA increased from 48 to 87% and comfort with TeamSTEPPS® principles increased from 68% to 85.5% This novel capstone provided students with the tools to synthesize HSS concepts through problem-solving processes and recognize EPA 13’s importance. Their increased capability to identify appropriate chain of command, escalate concerns, and recognize serious adverse patient events also has training and practice readiness implications.
    Keywords Communication ; Medical education ; Patient safety ; Quality improvement ; Transition to residency ; Team-based learning ; Special aspects of education ; LC8-6691 ; Medicine ; R
    Subject code 360
    Language English
    Publishing date 2023-04-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Reconstructing the Little Ice Age extent of Langfjordjøkelen, Arctic mainland Norway, as a baseline for assessing centennial-scale icefield recession

    Paul Weber / Harold Lovell / Liss M. Andreassen / Clare M. Boston

    Polar Research, Vol 39, Iss 0, Pp 1-

    2020  Volume 21

    Abstract: Current warming in the Arctic is occurring at a rate two to three times higher than that of the rest of the world, leading to rapid glacier wastage. In Arctic mainland Norway, the plateau icefield Langfjordjøkelen has experienced the greatest mass loss ... ...

    Abstract Current warming in the Arctic is occurring at a rate two to three times higher than that of the rest of the world, leading to rapid glacier wastage. In Arctic mainland Norway, the plateau icefield Langfjordjøkelen has experienced the greatest mass loss of all Norwegian glaciers (excluding Svalbard) in recent decades. In this article, we examine this decline in a centennial-scale context through geomorphological mapping and the analysis of historical aerial photographs and maps. This allows Langfjordjøkelen’s maximum Little Ice Age extent (ca. 1925) to be reconstructed, providing an important baseline for a long-term assessment of icefield change. At the LIA maximum, Langfjordjøkelen covered an area of 14.9 km2. A comparison of the LIA dimensions with the icefield extent in 1891/1902, as displayed on a historical map, reveals a substantial overestimation of the map-based glacier outline. The post-LIA evolution of Langfjordjøkelen has been characterized by sustained high rates of glacier recession. By 2018, the icefield had lost 57% (8.5 km2) of its original LIA area, at a decadal rate of 9%, and its outlet glaciers had reduced in average length by 42% (1 km), at an annual rate of 11 m. Langfjordjøkelen’s percentage area decline has been greater than that of Norwegian ice masses at lower latitudes where comparable long-term glacier change data are available. This indicates that there is a significant latitudinal variation in Norwegian glacier response to 20th century warming, likely influenced by an enhanced warming signal in Arctic Norway compared to the rest of the Norwegian mainland.
    Keywords glacier change ; glacier reconstruction ; glacial geomorphology ; historical maps ; plateau icefield ; Environmental sciences ; GE1-350 ; Oceanography ; GC1-1581
    Subject code 550
    Language English
    Publishing date 2020-08-01T00:00:00Z
    Publisher Norwegian Polar Institute
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Comfort With Telehealth Among Residents of an Underserved Urban Area

    Ann D. Bagchi / Kasny Damas / Nayeli Salazar de Noguera / Benjamin Melamed / Charles Menifield / Alok Baveja / Paul Weber / Shobha Swaminathan

    Journal of Primary Care & Community Health, Vol

    2022  Volume 13

    Abstract: Background: Deployment of telehealth has been touted as a means of reducing health disparities in underserved groups. However, efforts to reduce regulatory barriers have not been associated with greater telehealth uptake. The goal of this study was to ... ...

    Abstract Background: Deployment of telehealth has been touted as a means of reducing health disparities in underserved groups. However, efforts to reduce regulatory barriers have not been associated with greater telehealth uptake. The goal of this study was to examine engagement with technology among low-income people of color living in Newark, New Jersey. Methods: Using surveys and focus groups, we examined study participants’ daily use of technology (eg, Internet) and comfort with telehealth services (eg, use of teleconferencing for medication refills) before and after COVID-related social distancing mandates went into effect. Results: Use of technology was significantly lower in the pre-COVID period. However, prior months’ use of technology had a weak but significant correlation with comfort with telehealth ( r = .243, P = .005) in bivariate analyses and was the only significant predictor in multivariate analyses. Analyses of focus group discussions confirmed that lack of experience with technology and distrust of the security and privacy of digital systems were the most important barriers to comfort with telehealth in our sample. Conclusion: Our study found that approximately 20% of people in this under-resourced community lacked access to basic technologies necessary for successful deployment of telehealth services. The study’s timing provided an unexpected opportunity to compare experiences and attitudes relating to telehealth in 2 regulatory environments. Although uptake of telehealth services increased with the Federal governments’ relaxation of regulatory barriers, there was not a similar increase in comfort with telehealth use. Investments in broadband access and equipment should be accompanied by educational programs to increase day-to-day use of and comfort with associated technologies which would improve consumer confidence in telehealth.
    Keywords Computer applications to medicine. Medical informatics ; R858-859.7 ; Public aspects of medicine ; RA1-1270
    Subject code 303
    Language English
    Publishing date 2022-08-01T00:00:00Z
    Publisher SAGE Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Pulmonary Rehabilitation is Improved by In-Shoe Foot Orthosis Intervention

    Yves Jammes / Hanan Rkain / Jean Paul Weber / Patricia Griffon / Bruno Vie / Alain Palot / Pierre François Gallet

    European Medical Journal, Vol 5, Iss 1, Pp 41-

    2020  Volume 47

    Abstract: Some studies have found that patients with asthma have bilateral foot dorsal flexion limitations, contributing to impaired quality of life. The authors hypothesised that foot misalignments could also occur in patients with chronic obstructive pulmonary ... ...

    Abstract Some studies have found that patients with asthma have bilateral foot dorsal flexion limitations, contributing to impaired quality of life. The authors hypothesised that foot misalignments could also occur in patients with chronic obstructive pulmonary disease (COPD), and that foot orthoses could increase the motor benefits of their pulmonary rehabilitation (PR). Presented herein are the results from a nonrandomised controlled study in 40 patients with COPD. Twenty patients had foot misalignment (Group 1) and wore foot orthoses for a 1-month PR period. Their data were compared to those obtained in 20 other patients with COPD who had no foot misalignment and did not wear foot orthoses (Group 2). Bodily fatigue, 6-minute walk test (6MWT) distance, peak plantar flexion force (PFF), and oscillations of the centre of pressure (CoP) were measured. Measurements were performed prior to and following completion of PR (Groups 1 and 2), immediately after wearing the foot orthosis (Group 1), and after completion of PR plus foot orthoses (Group 1). In Group 2, PR increased the 6MWT distance, but did not increase PFF nor reduce CoP oscillations and fatigue scale. Wearing the foot orthosis for the first time significantly increased the 6MWT distance (+98+12 m). Following PR with foot orthoses (Group 1), a further increase in 6MWT distance occurred (+120+13 m), bodily fatigue was reduced, PFF increased, and CoP oscillations decreased. In patients with COPD and foot misalignment, foot orthoses enhanced the functional capacity and improved the postural control.
    Keywords 6-minute walk test (6mwt) ; foot orthosis ; plantar flexion force (pff) ; posturography ; pulmonary rehabilitation (pr) ; respiratory insufficiency ; Medicine ; R
    Subject code 796
    Language English
    Publishing date 2020-03-01T00:00:00Z
    Publisher European Medical Journal
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Adding body load modifies the vibratory sensation of the foot sole and affects the postural control

    Yves Jammes / Eva Ferrand / Corentin Fraud / Alain Boussuges / Jean Paul Weber

    Military Medical Research, Vol 5, Iss 1, Pp 1-

    2018  Volume 7

    Abstract: Abstract Background Heavy backpacks are often used by soldiers and firefighters. Weight carrying could reduce the speed and efficiency in task completion by altering the foot sole sensitivity and postural control. Methods In fifteen healthy subjects, we ... ...

    Abstract Abstract Background Heavy backpacks are often used by soldiers and firefighters. Weight carrying could reduce the speed and efficiency in task completion by altering the foot sole sensitivity and postural control. Methods In fifteen healthy subjects, we measured the changes in sensitivity to vibrations applied to the foot sole when standing upright or walking after load carrying (30% body weight). The participants were asked to judge different vibration amplitudes applied on the 2nd or 5th metatarsal head and the heel at two frequencies (25 and 150 Hz) to determine the vibration threshold and the global perceptual representation (Ѱ)of the vibration amplitude (Ф) given by the Stevens power function (Ѱ = k × Фn). Any increase in negative k value indicated a reduction in sensitivity to the lowest loads. Pedobarographic measurements, with computation of the center of pressure (COP) and its deviations, were performed during weight carrying. Results The 25-Hz vibration threshold significantly increased after weight carrying when standing upright or walking. After standing with the added loads, the absolute negative k value increased for the 25 Hz frequency. After walking with the added loads, the k coefficient increased for the two vibration frequencies. Weight carrying significantly increased both the CoP surface and CoP lateral deviation. Conclusions Our data show that weight carrying reduces the sensory pathways from the foot sole and accentuates the center of pressure deviations.
    Keywords Foot sole sensitivity ; Vibration ; Weight carrying ; Postural control ; Medicine (General) ; R5-920 ; Military Science ; U
    Subject code 796
    Language English
    Publishing date 2018-08-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Assessing Entrepreneurial Characteristics of Healthcare Students Participating in an Entrepreneurial-Medicine Curriculum [Version 2]

    Alexander Watson / Camden MacDowell / Gregg Khodorov / Julia Tartaglia / Paul Weber

    MedEdPublish, Vol 7, Iss

    2018  Volume 2

    Abstract: As innovation transforms the healthcare industry, medical institutions are increasingly incorporating business skills and concepts into their curricula. The goal of this study was to characterize the types of students who engage in these supplemental ... ...

    Abstract As innovation transforms the healthcare industry, medical institutions are increasingly incorporating business skills and concepts into their curricula. The goal of this study was to characterize the types of students who engage in these supplemental curricula with respect to four entrepreneurial characteristics: entrepreneurial interest, support, confidence, and intention. We sampled students participating in a healthcare Innovation Summit using a validated survey to assess these characteristics. The sampled population reported significantly positive Interest and Support regarding an entrepreneurial career (5.18 and 5.80; p-values <0.01), whereas Intention and Confidence did not significantly differ from neutral (4.02 and 3.78; p>0.05). There were significant positive correlations between individuals' entrepreneurial Interest and all other characteristics; demonstrated by Pearson's Correlation Coefficients of 0.74, 0.62, and 0.59 when comparing sample means of Interest versus Intention, Confidence, and Support, (p-values <0.05). In addition, significant correlation between Intention and Confidence was observed (Pearson's R = 0.78: p-values <0.05). Conversely, sample means for entrepreneurial Support were not significantly correlated with either Intent or Confidence (p-values >0.05). Our findings supply foundational data for understanding the growing cohort of individuals engaging in entrepreneurial-medicine. These data demonstrate the integrated nature of various entrepreneurial characteristics in these populations and support the idea that investment, which promotes one area, would translate to increases in others.
    Keywords Medical education ; Entrepreneurship education ; Healthcare innovation ; Innovation curriculum ; Special aspects of education ; LC8-6691 ; Medicine ; R
    Subject code 310
    Language English
    Publishing date 2018-10-01T00:00:00Z
    Publisher F1000 Research Ltd
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Nectin-4 Expression Is an Independent Prognostic Biomarker and Associated With Better Survival in Triple-Negative Breast Cancer

    Jasmin Zeindler / Savas Deniz Soysal / Salvatore Piscuoglio / Charlotte K. Y. Ng / Robert Mechera / Andrej Isaak / Walter Paul Weber / Simone Muenst / Christian Kurzeder

    Frontiers in Medicine, Vol

    2019  Volume 6

    Abstract: Background: Triple-negative breast cancer (TNBC) represents about 10-20% of all invasive breast cancers and is associated with a poor prognosis. The nectin cell adhesion protein 4 (Nectin-4) is a junction protein involved in the formation and maintenance ...

    Abstract Background: Triple-negative breast cancer (TNBC) represents about 10-20% of all invasive breast cancers and is associated with a poor prognosis. The nectin cell adhesion protein 4 (Nectin-4) is a junction protein involved in the formation and maintenance of cell junctions. Nectin-4 has previously shown to be expressed in about 60% of TNBC as well as in TNBC metastases, but to be absent in normal breast tissue, which makes it a potential specific target for TNBC therapy. Previous studies have shown an association of Nectin-4 protein expression with worse prognosis in TNBC in a small patient cohort. The aim of our study was to explore the role of Nectin-4 in TNBC and confirm its impact on survival in a larger TNBC patient cohort.Material and Methods: We performed immunohistochemical staining for Nectin-4 on a tissue microarray encompassing 148 TNBC cases with detailed clinical annotation and outcomes data.Results: A high expression of Nectin-4 was present in 86 (58%) of the 148 TNBC cases. In multivariate survival analysis, high expression of Nectin-4 was associated with a significantly better overall survival when compared with low expression of Nectin-4 (p < 0.001). Nectin-4-high expression was also significantly associated with a lower tumor stage (p = 0.025) and pN0 lymph node stage (p = 0.034).Conclusion: Our results confirm that expression of Nectin-4 serves as a potential prognostic marker in TNBC and is associated with a significantly better overall survival. In addition, Nectin-4 represents a potential target in TNBC, and its role in molecular defined breast cancer subtype should be investigated in larger patient cohorts.
    Keywords Nectin-4 ; breast cancer ; biomarkers ; prognosis ; triple-negative breast cancer ; Medicine (General) ; R5-920
    Subject code 616
    Language English
    Publishing date 2019-09-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Effects of biosolids on biodiesel crop yield and belowground communities

    Adair, Karen L / Anna-Marie Barnes / Benjamin R. Waterhouse / Gavin Lear / Mark Pizey / Michael Smith / Paul Weber / Stéphane Boyer / Steve Wratten

    Ecological engineering. 2014 July, v. 68

    2014  

    Abstract: Biofuels are an attractive alternative for fossil fuels and demand is growing rapidly, however the environmental impacts of biofuel production must be minimized. Replacing conventional fertilizers with biosolids, processed solids from municipal ... ...

    Abstract Biofuels are an attractive alternative for fossil fuels and demand is growing rapidly, however the environmental impacts of biofuel production must be minimized. Replacing conventional fertilizers with biosolids, processed solids from municipal wastewater treatment plants, has the benefit of utilizing a waste stream and avoiding some of the environmental impacts associated with conventional fertilizers, but the impacts of heavy metals in biosolids must be assessed. In a pot trial, we grew two oilseed crop species, Brassica napus and Camelina sativa, in soil amended with two levels biosolids and soil amended with urea. Seed yield and oil content were compared between soil treatments, and effects on soil chemistry, activity of microfauna, and bacterial and fungal community structure were quantified. We also measured the impacts of biosolids addition on the growth, survival and tissue chemistry of earthworms. Seed yield of plants grown in biosolids was comparable to or greater than that of plants fertilized with urea. Biosolids addition increased soil concentrations of plant nutrients, but also heavy metals (e.g. arsenic, lead, chromium and nickel). Microfaunal activity, as well as soil microbial community structure, was impacted by both fertilizer type and oilseed plant species. Earthworm biomass was enhanced by addition of biosolids though earthworms exposed to biosolids had elevated levels of copper. Our results suggest biosolids could effectively fertilize these oilseed crops and may enhance soil health, but impacts of heavy metals should be considered.
    Keywords arsenic ; biodiesel ; biomass ; biosolids ; Brassica napus ; Camelina sativa ; chromium ; community structure ; copper ; crops ; earthworms ; environmental impact ; fuel production ; fungal communities ; heavy metals ; lead ; lipid content ; mineral fertilizers ; municipal wastewater ; nickel ; nutrients ; oilseed crops ; seed yield ; soil ; soil amendments ; soil chemistry ; soil microorganisms ; soil quality ; urea ; wastewater treatment
    Language English
    Dates of publication 2014-07
    Size p. 270-278.
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 1127407-4
    ISSN 0925-8574
    ISSN 0925-8574
    DOI 10.1016/j.ecoleng.2014.03.083
    Database NAL-Catalogue (AGRICOLA)

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