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  1. Article ; Online: Effects of Synthesis Parameters on Structure and Antimicrobial Properties of Bacterial Cellulose/Hydroxyapatite/TiO

    Sknepnek, Aleksandra / Filipović, Suzana / Pavlović, Vladimir B / Mirković, Nemanja / Miletić, Dunja / Gržetić, Jelena / Mirković, Miljana

    Polymers

    2024  Volume 16, Issue 4

    Abstract: Bacterial cellulose (BC) is a highly pure polysaccharide biopolymer that can be produced by various bacterial genera. Even though BC lacks functional properties, its porosity, three-dimensional network, and high specific surface area make it a suitable ... ...

    Abstract Bacterial cellulose (BC) is a highly pure polysaccharide biopolymer that can be produced by various bacterial genera. Even though BC lacks functional properties, its porosity, three-dimensional network, and high specific surface area make it a suitable carrier for functional composite materials. In the present study, BC-producing bacteria were isolated from kombucha beverage and identified using a molecular method. Two sets of the BC hydrogels were produced in static conditions after four and seven days. Afterwards, two different synthesis pathways were applied for BC functionalization. The first method implied the incorporation of previously synthesized HAp/TiO
    Language English
    Publishing date 2024-02-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym16040470
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  2. Article ; Online: Anticancer effect of novel luteolin capped gold nanoparticles selectively cytotoxic towards human cervical adenocarcinoma HeLa cells: An in vitro approach.

    Matić, Ivana Z / Mraković, Ana / Rakočević, Zlatko / Stoiljković, Milovan / Pavlović, Vladimir B / Momić, Tatjana

    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)

    2023  Volume 80, Page(s) 127286

    Abstract: Background: Although luteolin has been confirmed as potent anticancer agent, its potential application as therapeutic is limited by its water solubility. To overcome this shortcoming nanoparticle technology approach was applied. Owing to their proven ... ...

    Abstract Background: Although luteolin has been confirmed as potent anticancer agent, its potential application as therapeutic is limited by its water solubility. To overcome this shortcoming nanoparticle technology approach was applied. Owing to their proven low toxicity and the possibility to be easily functionalized gold nanoparticles (AuNP) were the nanosystem of choice used in this study. Novel luteolin capped gold nanoparticles (AuNPL) were synthesized and their anticancer effect towards human cervical adenocarcinoma HeLa cells was investigated in vitro.
    Methods: AuNPL were synthesized by reducing chloroauric acid by trisodium citrate with subsequent addition of luteoline during synthesis and their physicochemical characterization was done. AuNPL cytotoxicity against HeLa, human malignant melanoma A375, and normal human keratinocytes HaCaT cells was tested by MTT cell survival assay, and their IC
    Results: Spherical AuNPL, stable in aqueous solution up to six months at 4 °C were obtained in the synthesis. The selectivity in the cytotoxic action of AuNPL on HeLa and A375 cancer cells compared with their cytotoxicity on normal keratinocytes HaCaT was observed. AuNPL exerted their cytotoxic activity against HeLa cells through accumulation of the cells in the subG1 phase of the cell cycle, inducing the apoptotic cell death mediated by the activation of caspase-3 - 8, and - 9. AuNPL antioxidative potential was confirmed by DPPH
    Conclusion: Synthesized AuNPL showed selective cytotoxic activity against HeLa cells, while being nontoxic and cytoprotective against HaCaT cells. The observed findings encourage further investigation of AuNPL as a promising novel anticancer agent.
    MeSH term(s) Humans ; HeLa Cells ; Luteolin/pharmacology ; Luteolin/chemistry ; Gold/pharmacology ; Gold/chemistry ; Reactive Oxygen Species/metabolism ; Hydrogen Peroxide/pharmacology ; Metal Nanoparticles/chemistry ; Apoptosis ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/chemistry ; Antioxidants/pharmacology ; Adenocarcinoma
    Chemical Substances Luteolin (KUX1ZNC9J2) ; Gold (7440-57-5) ; Reactive Oxygen Species ; 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid (28752-68-3) ; Hydrogen Peroxide (BBX060AN9V) ; Antineoplastic Agents ; Antioxidants
    Language English
    Publishing date 2023-08-22
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1236267-0
    ISSN 1878-3252 ; 1611-602X ; 0946-672X
    ISSN (online) 1878-3252 ; 1611-602X
    ISSN 0946-672X
    DOI 10.1016/j.jtemb.2023.127286
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2279: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article: Reduction in Pathogenic Biofilms by the Photoactive Composite of Bacterial Cellulose and Nanochitosan Dots under Blue and Green Light.

    Zmejkoski, Danica Z / Zdravković, Nemanja M / Budimir Filimonović, Milica D / Pavlović, Vladimir B / Butulija, Svetlana V / Milivojević, Dušan D / Marković, Zoran M / Todorović Marković, Biljana M

    Journal of functional biomaterials

    2024  Volume 15, Issue 3

    Abstract: In this study, nanochitosan dots (ChiDs) were synthesized using gamma rays and encapsulated in bacterial cellulose (BC) polymer matrix for antibiofilm potential in photodynamic therapy. The composites were analyzed for structural changes using SEM, AFM, ... ...

    Abstract In this study, nanochitosan dots (ChiDs) were synthesized using gamma rays and encapsulated in bacterial cellulose (BC) polymer matrix for antibiofilm potential in photodynamic therapy. The composites were analyzed for structural changes using SEM, AFM, FTIR, XRD, EPR, and porosity measurements. Additionally, ChiD release was assessed. The results showed that the chemical composition remained unaltered, but ChiD agglomerates embedded in BC changed shape (1.5-2.5 µm). Bacterial cellulose fibers became deformed and interconnected, with increased surface roughness and porosity and decreased crystallinity. No singlet oxygen formation was observed, and the total amount of released ChiD was up to 16.10%. Antibiofilm activity was higher under green light, with reductions ranging from 48 to 57% under blue light and 78 to 85% under green light. Methicillin-resistant
    Language English
    Publishing date 2024-03-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2648525-4
    ISSN 2079-4983
    ISSN 2079-4983
    DOI 10.3390/jfb15030072
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  4. Article ; Online: Structural, Mechanical, and Barrier Properties of the Polyvinylidene Fluoride-Bacterial Nanocellulose-Based Hybrid Composite.

    Janićijević, Aleksandra / Filipović, Suzana / Sknepnek, Aleksandra / Salević-Jelić, Ana / Jančić-Heinemann, Radmila / Petrović, Miloš / Petronijević, Ivan / Stamenović, Marina / Živković, Predrag / Potkonjak, Nebojša / Pavlović, Vladimir B

    Polymers

    2024  Volume 16, Issue 8

    Abstract: This study presents an analysis of films which consist of two layers; one layer is PVDF as the matrix, along with fillers ... ...

    Abstract This study presents an analysis of films which consist of two layers; one layer is PVDF as the matrix, along with fillers BaTiO
    Language English
    Publishing date 2024-04-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym16081033
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  5. Article ; Online: Structural Characterization of Nanocellulose/Fe

    Janićijević, Aleksandra / Pavlović, Vera P / Kovačević, Danijela / Perić, Marko / Vlahović, Branislav / Pavlović, Vladimir B / Filipović, Suzana

    Polymers

    2022  Volume 14, Issue 9

    Abstract: The rise of innovation in the electrical industry is driven by the controlled design of new materials. The hybrid materials based on magnetite/nanocellulose are highly interesting due to their various applications in medicine, ecology, catalysis and ... ...

    Abstract The rise of innovation in the electrical industry is driven by the controlled design of new materials. The hybrid materials based on magnetite/nanocellulose are highly interesting due to their various applications in medicine, ecology, catalysis and electronics. In this study, the structure and morphology of nanocellulose/magnetite hybrid nanomaterials were investigated. The effect of nanocellulose loading on the crystal structure of synthesized composites was investigated by XRD and FTIR methods. The presented study reveals that the interaction between the cellulose and magnetic nanoparticles depends on the nanocellulose content. Further, a transition from cellulose II to cellulose I allomorph is observed. SEM and EDS are employed to determine the variation in morphology with changes in component concentrations. By the calculation of magnetic interactions between adjacent Fe
    Language English
    Publishing date 2022-04-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym14091819
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Goat milk proteins enriched with Agaricus blazei Murrill ss. Heinem extracts: Electrophoretic, FTIR, DLS and microstructure characterization

    Minić, Dušanka A. Popović / Milinčić, Danijel D. / Kolašinac, Stefan / Rac, Vladislav / Petrović, Jovana / Soković, Marina / Banjac, Nebojša / Lađarević, Jelena / Vidović, Bojana B. / Kostić, Aleksandar Ž / Pavlović, Vladimir B. / Pešić, Mirjana B.

    Food chemistry. 2023 Feb. 15, v. 402

    2023  

    Abstract: This study aimed to characterize mixtures of goat milk proteins and Agaricus blazei Murrill (ABM) extracts (aqueous, AE and polysaccharides, PE). The mixtures showed stable particles with ζ-potential more negative than −41.1 mV. The addition of AMB ... ...

    Abstract This study aimed to characterize mixtures of goat milk proteins and Agaricus blazei Murrill (ABM) extracts (aqueous, AE and polysaccharides, PE). The mixtures showed stable particles with ζ-potential more negative than −41.1 mV. The addition of AMB extracts to goat milk did not result in a significant particle size change, whereas their addition to heated goat milk significantly increased mean particle diameter (from 194 nm to 225 nm). Fourier Transform Infrared Spectroscopy (FTIR) showed that ABM extracts provoked changes in the secondary structure of goat milk proteins and interactions between polysaccharides and milk proteins predominantly via hydrogen and/or glycoside bonds and hydrophobic interactions. The milk protein profiles revealed proteolytic activity in mixtures with AE resulting in the formation of five new polypeptides. The different microstructures of mixtures with AE and PE were found by Scanning Electron Microscopy (SEM). A schematic representation of possible milk proteins-ABM extracts interactions has been given.
    Keywords Agaricus subrufescens ; Fourier transform infrared spectroscopy ; electron microscopy ; electrophoresis ; food chemistry ; glycosides ; goat milk ; hydrogen ; hydrophobicity ; microstructure ; milk ; milk proteins ; particle size ; polypeptides ; polysaccharides ; proteolysis
    Language English
    Dates of publication 2023-0215
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 243123-3
    ISSN 1873-7072 ; 0308-8146
    ISSN (online) 1873-7072
    ISSN 0308-8146
    DOI 10.1016/j.foodchem.2022.134299
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 3634: Show issues

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  7. Article: Structural, optical, and bioimaging characterization of carbon quantum dots solvothermally synthesized from

    Marković, Zoran M / Budimir, Milica D / Danko, Martin / Milivojević, Dušan D / Kubat, Pavel / Zmejkoski, Danica Z / Pavlović, Vladimir B / Mojsin, Marija M / Stevanović, Milena J / Todorović Marković, Biljana M

    Beilstein journal of nanotechnology

    2023  Volume 14, Page(s) 165–174

    Abstract: Carbon quantum dots as a novel type of carbon nanomaterials have attracted the attention of many researchers because of their unique optical, antibacterial, and anticancer properties as well as their biocompatibility. In this study, for the first time, ... ...

    Abstract Carbon quantum dots as a novel type of carbon nanomaterials have attracted the attention of many researchers because of their unique optical, antibacterial, and anticancer properties as well as their biocompatibility. In this study, for the first time, carbon quantum dots were prepared from
    Language English
    Publishing date 2023-01-30
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2583584-1
    ISSN 2190-4286
    ISSN 2190-4286
    DOI 10.3762/bjnano.14.17
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  8. Article: Employing Gamma-Ray-Modified Carbon Quantum Dots to Combat a Wide Range of Bacteria.

    Marković, Zoran M / Mišović, Aleksandra S / Zmejkoski, Danica Z / Zdravković, Nemanja M / Kovač, Janez / Bajuk-Bogdanović, Danica V / Milivojević, Dušan D / Mojsin, Marija M / Stevanović, Milena J / Pavlović, Vladimir B / Marković, Biljana M Todorović

    Antibiotics (Basel, Switzerland)

    2023  Volume 12, Issue 5

    Abstract: Nowadays, it is a great challenge to develop new medicines for treating various infectious diseases. The treatment of these diseases is of utmost interest to further prevent the development of multi-drug resistance in different pathogens. Carbon quantum ... ...

    Abstract Nowadays, it is a great challenge to develop new medicines for treating various infectious diseases. The treatment of these diseases is of utmost interest to further prevent the development of multi-drug resistance in different pathogens. Carbon quantum dots, as a new member of the carbon nanomaterials family, can potentially be used as a highly promising visible-light-triggered antibacterial agent. In this work, the results of antibacterial and cytotoxic activities of gamma-ray-irradiated carbon quantum dots are presented. Carbon quantum dots (CQDs) were synthesized from citric acid by a pyrolysis procedure and irradiated by gamma rays at different doses (25, 50, 100 and 200 kGy). Structure, chemical composition and optical properties were investigated by atomic force microscopy, transmission electron microscopy, X-ray photoelectron spectroscopy, Fourier transform infrared spectroscopy, Raman spectroscopy, UV-Vis spectrometry and photoluminescence. Structural analysis showed that CQDs have a spherical-like shape and dose-dependent average diameters and heights. Antibacterial tests showed that all irradiated dots had antibacterial activity but CQDs irradiated with dose of 100 kGy had antibacterial activity against all seven pathogen-reference bacterial strains. Gamma-ray-modified CQDs did not show any cytotoxicity toward human fetal-originated MRC-5 cells. Moreover, fluorescence microscopy showed excellent cellular uptake of CQDs irradiated with doses of 25 and 200 kGy into MRC-5 cells.
    Language English
    Publishing date 2023-05-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics12050919
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  9. Article ; Online: Dielectric and Structural Properties of the Hybrid Material Polyvinylidene Fluoride-Bacterial Nanocellulose-Based Composite.

    Janićijević, Aleksandra / Filipović, Suzana / Sknepnek, Aleksandra / Vlahović, Branislav / Đorđević, Nenad / Kovacević, Danijela / Mirković, Miljana / Petronijević, Ivan / Zivković, Predrag / Rogan, Jelena / Pavlović, Vladimir B

    Polymers

    2023  Volume 15, Issue 20

    Abstract: In the search for environmentally friendly materials with a wide range of properties, polymer composites have emerged as a promising alternative due to their multifunctional properties. This study focuses on the synthesis of composite materials ... ...

    Abstract In the search for environmentally friendly materials with a wide range of properties, polymer composites have emerged as a promising alternative due to their multifunctional properties. This study focuses on the synthesis of composite materials consisting of four components: bacterial nanocellulose (BNC) modified with magnetic Fe
    Language English
    Publishing date 2023-10-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym15204080
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  10. Article ; Online: Freeze vs. Spray Drying for Dry Wild Thyme (

    Jovanović, Aleksandra A / Lević, Steva M / Pavlović, Vladimir B / Marković, Smilja B / Pjanović, Rada V / Đorđević, Verica B / Nedović, Viktor / Bugarski, Branko M

    Molecules (Basel, Switzerland)

    2021  Volume 26, Issue 13

    Abstract: Freeze drying was compared with spray drying regarding feasibility to process wild thyme drugs in order to obtain dry formulations at laboratory scale starting from liquid extracts produced by different extraction methods: maceration and heat-, ... ...

    Abstract Freeze drying was compared with spray drying regarding feasibility to process wild thyme drugs in order to obtain dry formulations at laboratory scale starting from liquid extracts produced by different extraction methods: maceration and heat-, ultrasound-, and microwave-assisted extractions. Higher total powder yield (based on the dry weight prior to extraction) was achieved by freeze than spray drying and lower loss of total polyphenol content (TPC) and total flavonoid content (TFC) due to the drying process. Gelatin as a coating agent (5%
    MeSH term(s) Freeze Drying ; Gelatin/chemistry ; Plant Extracts/chemistry ; Spray Drying ; Thymus Plant/chemistry
    Chemical Substances Plant Extracts ; Gelatin (9000-70-8)
    Language English
    Publishing date 2021-06-28
    Publishing country Switzerland
    Document type Comparative Study ; Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules26133933
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    In stock of ZB MED Cologne/Königswinter

    Zs.MO 81: Show issues

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