Article ; Online: Widespread dermatophytosis in a healthy adolescent: the first report of multidrug-resistant Trichophyton indotineae infection in the UAE.
Acta dermatovenerologica Alpina, Pannonica, et Adriatica
2024 Volume 33, Issue 1, Page(s) 53–55
Abstract: A multidrug-resistant dermatophyte species recently arose in India, first described as terbinafine-resistant Trichophyton interdigitale and soon given a separate name: T. indotineae. Thanks to its treatment recalcitrance, person-to-person spread, and ... ...
Abstract | A multidrug-resistant dermatophyte species recently arose in India, first described as terbinafine-resistant Trichophyton interdigitale and soon given a separate name: T. indotineae. Thanks to its treatment recalcitrance, person-to-person spread, and frequent travel, before long it was identified in many countries on all continents. We describe here the case of a boy with widespread, extremely pruritic, inflammatory dermatophytosis affecting his face, neck, trunk, and extremities, unsuccessfully treated for months with oral terbinafine and fluconazole and a range of topical antimycotics. Qualitative polymerase chain reaction of skin scrapings from his lesions identified a T. interdigitale complex fungus, highly probably T. indotineae due to conspecificity and antifungal resistance. Oral itraconazole, administered over 8 weeks, cleared the infection. Because the patient had not traveled outside the United Arab Emirates for months before the infection became obvious, it must have been acquired from a local source. |
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MeSH term(s) | Male ; Adolescent ; Humans ; Terbinafine/therapeutic use ; Antifungal Agents/therapeutic use ; Trichophyton ; Tinea/diagnosis ; Tinea/drug therapy ; Microbial Sensitivity Tests |
Chemical Substances | Terbinafine (G7RIW8S0XP) ; Antifungal Agents |
Language | English |
Publishing date | 2024-02-12 |
Publishing country | Slovenia |
Document type | Journal Article ; Case Reports |
ZDB-ID | 1235900-2 |
ISSN | 1581-2979 ; 1318-4458 ; 0302-4466 |
ISSN (online) | 1581-2979 |
ISSN | 1318-4458 ; 0302-4466 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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