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  1. Article ; Online: Monte Carlo techniques for in-situ specific activity estimation of radionuclides with a portable coaxial HPGe: preliminary results.

    Tarabini, Enrico / Cremonesi, Oliviero / Di Stefano, Elena / Pedrini, Daniele / Clemenza, Massimiliano

    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine

    2023  Volume 196, Page(s) 110768

    Abstract: In this work, gamma-ray spectrometry with HPGe detectors is used to measure radionuclides' specific activity ( ... ...

    Abstract In this work, gamma-ray spectrometry with HPGe detectors is used to measure radionuclides' specific activity (A
    Language English
    Publishing date 2023-03-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 1142596-9
    ISSN 1872-9800 ; 0883-2889 ; 0969-8043
    ISSN (online) 1872-9800
    ISSN 0883-2889 ; 0969-8043
    DOI 10.1016/j.apradiso.2023.110768
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The effect of toothpaste with reduced concentration of fluoride-containing sodium trimetaphosphate and polyols on initial enamel erosion.

    de Toledo, Priscila Toninatto Alves / Delbem, Alberto Carlos Botazzo / Cannon, Mark Lloyd / Sakamoto, Amanda Eliane / Pedrini, Denise

    Clinical oral investigations

    2022  Volume 26, Issue 12, Page(s) 7243–7252

    Abstract: Objectives: This in vitro study evaluated the efficacy of toothpaste containing fluoride (F), sodium trimetaphosphate (TMP), and xylitol and erythritol (XE) to inhibit or repair initial enamel erosion lesions.: Materials and methods: Bovine enamel ... ...

    Abstract Objectives: This in vitro study evaluated the efficacy of toothpaste containing fluoride (F), sodium trimetaphosphate (TMP), and xylitol and erythritol (XE) to inhibit or repair initial enamel erosion lesions.
    Materials and methods: Bovine enamel blocks (n = 120) were selected according to surface hardness (SH) and randomly divided into 5 experimental groups (n = 24 blocks/group): Placebo (no F, TMP, XE); 1100 ppm F; 16% xylitol + 4% erythritol (XE); 200 ppm F + 0.2% TMP (200 ppm F/TMP); and 200 ppm F + 0.2% TMP + 16% xylitol + 4% erythritol (200 ppm F/TMP/XE). The sound and softened blocks were immersed in toothpaste slurry in human saliva for 2 min. The blocks were then submitted to 4 erosive challenges in citric acid (0.75%, pH 3.5), each challenge for 1 min, with stirring. The SH of the blocks was determined after treatment (t) and after the 4 erosive challenges. In addition, the precipitates were analyzed by scanning electron microscopy (SEM). Variables were submitted to a two-way repeated-measures analysis of variance followed by a Student-Newman-Keuls test (p < 0.05).
    Results: Toothpaste containing 200 ppm F/TMP/XE led to the highest protective and repair effect compared to the other groups (p < 0.001). The protective and repair effect was XE > 200 ppm F/TMP > 1100 ppm F > placebo (p < 0.001). All groups produced precipitates with a thicker layer for XE and TMP groups.
    Conclusions: Toothpaste containing 200 ppm F, TMP, and polyols demonstrated a superior protective and repair effect in initial enamel erosive lesions in vitro.
    Clinical relevance: Toothpaste containing F and polyols could be an advantage in patients affected by dental erosion, due to its higher preventive potential, mainly in individuals who frequently drink acidic beverages. However, future studies are needed to confirm these results.
    MeSH term(s) Animals ; Cattle ; Humans ; Cariostatic Agents/pharmacology ; Dental Enamel ; Erythritol/pharmacology ; Fluorides/analysis ; Hardness ; Hydrogen-Ion Concentration ; Sodium Fluoride/pharmacology ; Toothpastes/pharmacology ; Toothpastes/therapeutic use ; Xylitol/pharmacology
    Chemical Substances Cariostatic Agents ; Erythritol (RA96B954X6) ; Fluorides (Q80VPU408O) ; polyol ; Sodium Fluoride (8ZYQ1474W7) ; Toothpastes ; trimetaphosphoric acid (H6C6T4285H) ; Xylitol (VCQ006KQ1E)
    Language English
    Publishing date 2022-08-19
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1364490-7
    ISSN 1436-3771 ; 1432-6981
    ISSN (online) 1436-3771
    ISSN 1432-6981
    DOI 10.1007/s00784-022-04684-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: A study on the possible merits of using symptomatic cases to trace the development of the COVID-19 pandemic.

    Bonifazi, Gianluca / Lista, Luca / Menasce, Dario / Mezzetto, Mauro / Pedrini, Daniele / Spighi, Roberto / Zoccoli, Antonio

    European physical journal plus

    2021  Volume 136, Issue 5, Page(s) 481

    Abstract: In a recent work, we introduced a novel method to compute the effective reproduction ... ...

    Abstract In a recent work, we introduced a novel method to compute the effective reproduction number
    Language English
    Publishing date 2021-05-03
    Publishing country Germany
    Document type Journal Article
    ISSN 2190-5444
    ISSN (online) 2190-5444
    DOI 10.1140/epjp/s13360-021-01448-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Study on the effects of the restrictive measures for containment of the COVID-19 pandemic on the reproduction number

    Bonifazi, Gianluca / Lista, Luca / Menasce, Dario / Mezzetto, Mauro / Pedrini, Daniele / Spighi, Roberto / Zoccoli, Antonio

    European physical journal plus

    2021  Volume 136, Issue 12, Page(s) 1208

    Abstract: Since November 6th, 2020, Italian regions have been classified according to four levels, corresponding to specific risk scenarios, for which specific restrictive measures have been foreseen. By analyzing the time evolution of the reproduction ... ...

    Abstract Since November 6th, 2020, Italian regions have been classified according to four levels, corresponding to specific risk scenarios, for which specific restrictive measures have been foreseen. By analyzing the time evolution of the reproduction number
    Language English
    Publishing date 2021-12-03
    Publishing country Germany
    Document type Journal Article
    ISSN 2190-5444
    ISSN (online) 2190-5444
    DOI 10.1140/epjp/s13360-021-02076-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A simplified estimate of the effective reproduction number

    Bonifazi, Gianluca / Lista, Luca / Menasce, Dario / Mezzetto, Mauro / Pedrini, Daniele / Spighi, Roberto / Zoccoli, Antonio

    European physical journal plus

    2021  Volume 136, Issue 4, Page(s) 386

    Abstract: A simplified method to ... ...

    Abstract A simplified method to compute
    Language English
    Publishing date 2021-04-11
    Publishing country Germany
    Document type Journal Article
    ISSN 2190-5444
    ISSN (online) 2190-5444
    DOI 10.1140/epjp/s13360-021-01339-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: SARS-CoV-2 and finding of vein thrombosis: can IMPROVE and IMPROVEDD scores predict COVID-19 outcomes?

    Greco, S / Zenunaj, G / Bonsi, B / Bella, A / Lopreiato, M / Luciani, F / Pedrini, D / Vestita, G / Dalla Nora, E / Passaro, A

    European review for medical and pharmacological sciences

    2021  Volume 25, Issue 4, Page(s) 2123–2130

    Abstract: Objective: Diffuse thrombosis represents one of the most predominant causes of death by COVID-19 and SARS-CoV-2 infection seems to increase the risk of developing venous thromboembolic diseases (VTE). Aim of this study is to analyze the relationship ... ...

    Abstract Objective: Diffuse thrombosis represents one of the most predominant causes of death by COVID-19 and SARS-CoV-2 infection seems to increase the risk of developing venous thromboembolic diseases (VTE). Aim of this study is to analyze the relationship between validated predictive scores for VTE such as IMPROVE and IMPROVEDD and: (1) Intensification of Care (IoC, admission to Pulmonology Department or Intensive Care Unit) (2) in-hospital mortality rate 3) 30-days mortality rate.
    Patients and methods: We retrospectively evaluated 51 adult patients with laboratory diagnosis of SARS-CoV-2 infection and calculated IMPROVE and IMPROVEDD scores. All patients underwent venous color-Doppler ultrasound of the lower limbs to assess the presence of superficial vein thrombosis (SVT) and/or deep vein thrombosis (DVT). Patients with normal values of D-dimer did not receive heparin therapy (LMWH); patients with ≥ 4 ULN values of D-dimer or with a diagnosis of DVT were treated with therapeutic LMWH dosage, while the remaining patients were treated with prophylactic LMWH dosages.
    Results: We found strong relations between IMPROVE score and the need for IoC and with the in-hospital mortality rate and between the IMPROVEDD score and the need for IoC. We defined that an IMPROVE score greater than 4 points was significantly associated to in-hospital mortality rate (p = 0.05), while an IMPROVEDD score greater than 3 points was associated with the need for IoC (p = 0.04). Multivariate logistic analysis showed how IMPROVE score was significantly associated to in-hospital and 30-days mortality rates.
    Conclusions: IMPROVE score can be considered an independent predictor of in-hospital and 30-days mortality.
    MeSH term(s) Adult ; COVID-19/blood ; COVID-19/complications ; COVID-19/diagnostic imaging ; COVID-19/mortality ; Critical Care/statistics & numerical data ; Disease-Free Survival ; Fibrin Fibrinogen Degradation Products/analysis ; Fibrinolytic Agents/administration & dosage ; Fibrinolytic Agents/therapeutic use ; Heparin, Low-Molecular-Weight/administration & dosage ; Heparin, Low-Molecular-Weight/therapeutic use ; Humans ; Italy ; Logistic Models ; Lower Extremity/diagnostic imaging ; Multivariate Analysis ; Retrospective Studies ; Risk Assessment ; Risk Factors ; SARS-CoV-2 ; Ultrasonography, Doppler, Duplex ; Venous Thrombosis/diagnostic imaging ; Venous Thrombosis/etiology ; Venous Thrombosis/mortality ; Venous Thrombosis/prevention & control
    Chemical Substances Fibrin Fibrinogen Degradation Products ; Fibrinolytic Agents ; Heparin, Low-Molecular-Weight ; fibrin fragment D
    Language English
    Publishing date 2021-03-04
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 605550-3
    ISSN 2284-0729 ; 1128-3602 ; 0392-291X
    ISSN (online) 2284-0729
    ISSN 1128-3602 ; 0392-291X
    DOI 10.26355/eurrev_202102_25118
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Hydraulic conductance of dentin after treatment with fluoride toothpaste containing sodium trimetaphosphate microparticles or nanoparticles.

    Favretto, Carla Oliveira / Delbem, Alberto Carlos Botazzo / Toledo, Priscila Toninatto Alves / Pedrini, Denise

    Clinical oral investigations

    2020  Volume 25, Issue 4, Page(s) 2069–2076

    Abstract: Objectives: To evaluate the hydraulic conductance of dentin after treatment with fluoride toothpastes containing sodium trimetaphosphate microparticles (TMPmicro) or nanoparticles (TMPnano).: Materials and methods: The dentinal tubules of bovine ... ...

    Abstract Objectives: To evaluate the hydraulic conductance of dentin after treatment with fluoride toothpastes containing sodium trimetaphosphate microparticles (TMPmicro) or nanoparticles (TMPnano).
    Materials and methods: The dentinal tubules of bovine dentin blocks (4 × 4 × 1 mm) were unobstructed for determination of the maximum hydraulic conductance of the dentin. The dentin blocks were randomized into four groups (n = 15/group) of toothpastes (placebo, 1100 ppm F, and 1100 with 3% TMPmicro or 3% TMPnano) which were applied for 7 days (2×/day) using a brushing machine. The dentin surface (5/group) was analyzed by scanning electron microscopy. The hydraulic conductance post-treatment was measured in the other ten blocks. Thereafter, the same blocks were immersed in citric acid (pH 3.2) for 1 min, and the conductance was determined again. The data were submitted to 2-way ANOVA repeated measures, followed by the Student-Newman-Keuls test (p < 0.05).
    Results: The percentage conductance reduction post-treatment for the groups were placebo = 1100 ppm F < 1100 TMPnano < 1100 TMPmicro (p < 0.001). After acid attack, the percentage reduction was placebo < 1100 ppm F < 1100 TMPnano < 1100 TMPmicro (p < 0.001). The toothpastes containing TMP showed the highest obliteration of dentinal tubules.
    Conclusions: The addition of TMPmicro to fluoride toothpaste produced a greater reduction in hydraulic conductance when compared with 1100 ppm F toothpaste.
    Clinical relevance: The increased capacity of toothpastes containing TMP to reduce hydraulic conductance indicates their potential to reduce symptoms of dentinal hypersensitivity.
    MeSH term(s) Animals ; Cattle ; Dentin ; Fluorides/pharmacology ; Humans ; Nanoparticles ; Polyphosphates ; Sodium Fluoride ; Toothpastes/pharmacology
    Chemical Substances Polyphosphates ; Toothpastes ; Sodium Fluoride (8ZYQ1474W7) ; trimetaphosphoric acid (H6C6T4285H) ; Fluorides (Q80VPU408O)
    Language English
    Publishing date 2020-08-18
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1364490-7
    ISSN 1436-3771 ; 1432-6981
    ISSN (online) 1436-3771
    ISSN 1432-6981
    DOI 10.1007/s00784-020-03516-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: A Statistical Analysis of Death Rates in Italy for the Years 2015-2020 and a Comparison with the Casualties Reported from the COVID-19 Pandemic.

    Bonifazi, Gianluca / Lista, Luca / Menasce, Dario / Mezzetto, Mauro / Oliva, Alberto / Pedrini, Daniele / Spighi, Roberto / Zoccoli, Antonio

    Infectious disease reports

    2021  Volume 13, Issue 2, Page(s) 285–301

    Abstract: We analyze the data about casualties in Italy in the period 1 January 2015 to 30 September 2020 released by the Italian National Institute of Statistics (ISTAT). The aim of this article was the description of a statistically robust methodology to extract ...

    Abstract We analyze the data about casualties in Italy in the period 1 January 2015 to 30 September 2020 released by the Italian National Institute of Statistics (ISTAT). The aim of this article was the description of a statistically robust methodology to extract quantitative values for the seasonal excesses of deaths featured by the data, accompanying them with correct estimates of the relative uncertainties. We will describe the advantages of the method adopted with respect to others listed in literature. The data exhibit a clear sinusoidal behavior, whose fit allows for a robust subtraction of the baseline trend of casualties in Italy, with a surplus of mortality in correspondence to the flu epidemics in winter and to the hottest periods in summer. The overall quality of the fit to the data turns out to be very good, an indication of the validity of the chosen model. We discuss the trend of casualties in Italy by different classes of ages and for the different genders. We finally compare the data-subtracted casualties, as reported by ISTAT, with those reported by the Italian Department for Civil Protection (DPC) relative to the deaths directly attributed to the Coronavirus Disease 2019 caused by the SARS-CoV-2 virus (COVID-19), and we point out the differences in the two samples, collected under different assumptions.
    Language English
    Publishing date 2021-04-01
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2036-7430
    ISSN 2036-7430
    DOI 10.3390/idr13020030
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: In vitro Evaluation of Surface Free Energy of Dentin after Treatment with Sodium Trimetaphosphate Associated or Not with Fluoride, Exposed or Not to Calcium.

    Oliveira, Lenara Queiroz Chaves / Delbem, Alberto Carlos Botazzo / Morais, Leonardo Antônio de / Gonçalves, Silvio César / Souza, José Antonio Santos / Pedrini, Denise

    Caries research

    2021  Volume 56, Issue 1, Page(s) 81–90

    Abstract: It has been stated that sodium trimetaphosphate (TMP) promotes a more anionic dentin surface inducing greater calcium (Ca) and phosphate precipitation. The aim of the present study was to evaluate in vitro the surface free energy (γs) of dentin after ... ...

    Abstract It has been stated that sodium trimetaphosphate (TMP) promotes a more anionic dentin surface inducing greater calcium (Ca) and phosphate precipitation. The aim of the present study was to evaluate in vitro the surface free energy (γs) of dentin after treatment with TMP associated or not with fluoride (F), exposed or not to Ca, as well as the adsorption of TMP, F, and Ca by dentin. Bovine dentin blocks (n = 12 blocks/group) were treated with solutions containing TMP at 0, 1, 3, or 9 (w/v) followed or not by the application of Ca. These solutions were or were not associated to 1,100 ppm F. F, Ca, and TMP were determined in the solutions before and after the treatment to calculate the adsorption by dentin. To analyze the γs of dentin, the apolar (γsLW), and polar (γsAB), components were determined by contact angle measurement. Data were submitted to 2-way ANOVA followed by the Student-Newman-Keuls test (p < 0.05). TMP reduces γs of dentin and increases electron donor sites (γs-). Higher values of γs- led to higher adsorption of Ca (p < 0.001). The F/TMP association did not change γs or γsLW and reduced the values of γs-, but the adsorption of Ca was higher. There was correlation between the adsorption of TMP and γs- (Pearson's r = 0.801; p < 0.001) and F (Pearson's r = 0.871, p < 0.001). It is possible to conclude that TMP increased γs- and Ca adsorption, and reduced γs. The association with F increased the adsorption of TMP without rising γs-; however, there was higher adsorption of Ca.
    MeSH term(s) Animals ; Calcium ; Cattle ; Dentin ; Fluorides/pharmacology ; Humans ; Polyphosphates/pharmacology ; Sodium Fluoride/pharmacology
    Chemical Substances Polyphosphates ; Sodium Fluoride (8ZYQ1474W7) ; trimetaphosphoric acid (H6C6T4285H) ; Fluorides (Q80VPU408O) ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2021-10-26
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 390575-5
    ISSN 1421-976X ; 0008-6568
    ISSN (online) 1421-976X
    ISSN 0008-6568
    DOI 10.1159/000520162
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book ; Online: CovidStat project data

    Lista, Luca / Menasce, Dario / Mezzetto, Mauro / Pedrini, Daniele / Spighi, Roberto

    2020  

    Abstract: This record contains the daily updated data of the CovidStat project. CovidStat is a project carried out by the CovidStat Working Group at INFN, whose creation was promoted within the Italian National Institute of Nuclear Physics with the aim of making a ...

    Abstract This record contains the daily updated data of the CovidStat project. CovidStat is a project carried out by the CovidStat Working Group at INFN, whose creation was promoted within the Italian National Institute of Nuclear Physics with the aim of making a statistical analysis of the data provided daily by the Civil Protection on the spread of the pandemic in Italy. CovidStat data can interactively be browsed at https://covid19.infn.it.
    Keywords COVID-19 ; CovidStat project ; FAIR data ; Open Science ; covid19
    Publishing date 2020-09-12
    Publishing country it
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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