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  1. Article ; Online: The Continuum of Severity of Functional Impairment Due to Indoor Air Symptoms: Prevalence and Determinants.

    Eidstø, Einar / Selinheimo, Sanna / Lampi, Jussi / Salmela, Anniina / Pekkanen, Juha

    Journal of occupational and environmental medicine

    2023  Volume 65, Issue 9, Page(s) 717–724

    Abstract: Objective: The aim of the study is to study functional impairment due to indoor air-related symptoms and associated characteristics.: Methods: A questionnaire survey of a random sample of Finnish people aged 25 to 64 years. Analyses were done using ... ...

    Abstract Objective: The aim of the study is to study functional impairment due to indoor air-related symptoms and associated characteristics.
    Methods: A questionnaire survey of a random sample of Finnish people aged 25 to 64 years. Analyses were done using multivariate multinomial logistic regression.
    Results: A total of 23.1% reported indoor air-related symptoms, 1.8% severe functional impairment due to symptoms, 5.3% moderate, 11.1% mild, and 4.9% reported no impairment. Those with severe functional impairment showed the strongest associations with comorbid diseases, for example, asthma and irritable bowel syndrome, perceived sensitivities to several environmental factors, like chemicals, and likelihood of having symptoms in multiple organs, while those with no or little functional impairment showed weak or even inverse associations. Similar results emerged with severity of indoor air-related symptoms.
    Conclusions: Individuals with indoor air-related symptoms are a very heterogeneous group. This should be better considered in future research and clinical practice.
    MeSH term(s) Humans ; Air Pollution, Indoor/analysis ; Prevalence ; Asthma/epidemiology ; Surveys and Questionnaires ; Logistic Models
    Language English
    Publishing date 2023-05-23
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1223932-x
    ISSN 1536-5948 ; 1076-2752
    ISSN (online) 1536-5948
    ISSN 1076-2752
    DOI 10.1097/JOM.0000000000002884
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Tracking an occluded visual target with sequences of saccades.

    Tammi, Tuisku / Pekkanen, Jami / Tuhkanen, Samuel / Oksama, Lauri / Lappi, Otto

    Journal of vision

    2022  Volume 22, Issue 1, Page(s) 9

    Abstract: Gaze behavior during visual tracking consists of a combination of pursuit and saccadic movements. When the tracked object is intermittently occluded, the role of smooth pursuit is reduced, with a corresponding increase in the role of saccades. However, ... ...

    Abstract Gaze behavior during visual tracking consists of a combination of pursuit and saccadic movements. When the tracked object is intermittently occluded, the role of smooth pursuit is reduced, with a corresponding increase in the role of saccades. However, studies of visual tracking during occlusion have focused only on the first few saccades, usually with occlusion periods of less than 1 second in duration. We investigated tracking on a circular trajectory with random occlusions and found that an occluded object can be tracked reliably for up to several seconds with mainly anticipatory saccades and very little smooth pursuit. Furthermore, we investigated the accumulation of uncertainty in prediction and found that prediction errors seem to accumulate faster when an absolute reference frame is not available during tracking. We suggest that the observed saccadic tracking reflects the use of a time-based internal estimate of object position that is anchored to the environment via fixations.
    MeSH term(s) Humans ; Psychomotor Performance ; Pursuit, Smooth ; Saccades ; Sensation
    Language English
    Publishing date 2022-02-02
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2106064-2
    ISSN 1534-7362 ; 1534-7362
    ISSN (online) 1534-7362
    ISSN 1534-7362
    DOI 10.1167/jov.22.1.9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Parent's self-reported indoor environment-related symptoms and health worry increase symptom reports among their children at school-Study in two independent populations.

    Selinheimo, Sanna / Lampi, Jussi / Pekkanen, Juha

    Indoor air

    2021  Volume 31, Issue 5, Page(s) 1298–1307

    Abstract: Little is known whether parent's indoor environment quality (IEQ)-related symptoms or health perceptions influence the risk of self- or parent-reported symptoms in their children. We assessed (i) the association of parents' IEQ-related symptoms with IEQ- ... ...

    Abstract Little is known whether parent's indoor environment quality (IEQ)-related symptoms or health perceptions influence the risk of self- or parent-reported symptoms in their children. We assessed (i) the association of parents' IEQ-related symptoms with IEQ-related symptoms in their children at school and (ii) whether parental IEQ-related health worry increases the risk for children's symptoms. We used two Finnish studies: a national, population-based survey of indoor air and related health problems (n = 611 parents) and a subset of survey for all primary school pupils (grade 3-6) and their parents in Helsinki, which also included school IEQ-related symptoms reported by children (n = 1617 parent-child dyads). In the school survey, parent's own symptoms increased strongly their reporting of their children's symptoms at school (aOR 4.0, 95% CI 2.7-6.0 for parents experiencing a lot of symptoms) and also symptoms reported by the child itself (aOR 2.2, 95% CI 1.5-3.1). Similar, but slightly weaker associations were seen with parental IEQ-related health worries. Results remained unchanged when adjusted for the IEQ of school buildings or parental and children's allergic diseases. Similar associations were seen in the national survey between parent's symptoms at work and child's symptoms at school. The results suggest that parents' health perceptions may increase the reporting of children's IEQ-related symptoms even more than is typically seen for many indoor air contaminants.
    MeSH term(s) Air Pollution, Indoor/statistics & numerical data ; Anxiety ; Environmental Exposure/statistics & numerical data ; Environmental Health ; Finland ; Humans ; Schools ; Self Report ; Students ; Surveys and Questionnaires ; Symptom Flare Up
    Language English
    Publishing date 2021-05-06
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1081722-0
    ISSN 1600-0668 ; 0905-6947
    ISSN (online) 1600-0668
    ISSN 0905-6947
    DOI 10.1111/ina.12836
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Comorbidities associated with adult asthma: a population-based matched cohort study in Finland.

    Lemmetyinen, Riikka Emilia / Toppila-Salmi, Sanna Katriina / But, Anna / Renkonen, Risto / Pekkanen, Juha / Haukka, Jari / Karjalainen, Jussi

    BMJ open respiratory research

    2024  Volume 11, Issue 1

    Abstract: Background: Asthma is a common chronic disease characterised by variable respiratory symptoms and airflow limitation, affecting roughly 4%-10% of the adult population. Adult asthma is associated with higher all-cause mortality compared to individuals ... ...

    Abstract Background: Asthma is a common chronic disease characterised by variable respiratory symptoms and airflow limitation, affecting roughly 4%-10% of the adult population. Adult asthma is associated with higher all-cause mortality compared to individuals without asthma. In this study, we investigate the comorbidities that may affect the management of asthma.
    Methods: Total of 1648 adults with asthma and 3310 individuals without asthma aged 30-93 were matched with age, gender and area of residency, and followed from 1 January 1997 to 31 December 2013. Baseline information was collected with questionnaires 1997 and follow-up register data from the national discharge registry Finnish Institute for Health and Welfare. Data included diagnoses from outpatient care and day surgery of specialised health care, and data from inpatient care of specialised and primary health care. We included all main diagnoses that had at minimum 200 events and number of diagnoses based on their common appearance with adult asthma.
    Results: The mean follow-up time varied between 14.2 and 15.1 years, and age at the time of enrolment was 53.9 years for subjects without asthma and 54.4 years for patients with asthma. Chronic obstructive pulmonary disease was 10 times more common among asthmatics. Risk of acute rhinosinusitis, chronic rhinosinusitis with nasal polyps, atopic dermatitis and vocal cord dysfunction was fourfold and risk of pneumonia, and chronic rhinosinusitis was 2.5 times more common among asthmatics. Sleep apnoea, gastro-oesophageal reflux disease, diabetes, allergic rhinitis and dysfunctional breathing were twofold and cataract nearly twofold higher in the asthmatic group. Adult asthma was also significantly associated with musculoskeletal diseases, incontinence and bronchiectasis.
    Conclusions: The most common and most severe comorbidity of adult asthma in this study was chronic obstructive pulmonary disease. Other common comorbidities of adult asthma include acute rhinosinusitis, chronic rhinosinusitis with nasal polyps, atopic dermatitis, allergic rhinitis, dysfunctional breathing, diabetes, pneumonia, sleep apnoea and gastro-oesophageal reflux disease.
    MeSH term(s) Adult ; Humans ; Finland/epidemiology ; Dermatitis, Atopic/complications ; Dermatitis, Atopic/epidemiology ; Cohort Studies ; Nasal Polyps/complications ; Nasal Polyps/epidemiology ; Asthma/epidemiology ; Asthma/complications ; Comorbidity ; Pulmonary Disease, Chronic Obstructive/epidemiology ; Pulmonary Disease, Chronic Obstructive/complications ; Sinusitis/epidemiology ; Sinusitis/complications ; Sinusitis/diagnosis ; Rhinitis, Allergic/complications ; Rhinitis, Allergic/epidemiology ; Chronic Disease ; Gastroesophageal Reflux/epidemiology ; Pneumonia/epidemiology ; Diabetes Mellitus/epidemiology ; Sleep Apnea Syndromes/complications
    Language English
    Publishing date 2024-03-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 2736454-9
    ISSN 2052-4439 ; 2052-4439
    ISSN (online) 2052-4439
    ISSN 2052-4439
    DOI 10.1136/bmjresp-2023-001959
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Can gaze control steering?

    Tuhkanen, Samuel / Pekkanen, Jami / Mole, Callum / Wilkie, Richard M / Lappi, Otto

    Journal of vision

    2023  Volume 23, Issue 7, Page(s) 12

    Abstract: When steering a trajectory, we direct our gaze to locations (1-3 s ahead) that we want to steer through. How and why are these active gaze patterns conducive to successful steering? While various sources of visual information have been identified that ... ...

    Abstract When steering a trajectory, we direct our gaze to locations (1-3 s ahead) that we want to steer through. How and why are these active gaze patterns conducive to successful steering? While various sources of visual information have been identified that could support steering control, the role of stereotypical gaze patterns during steering remains unclear. Here, experimental and computational approaches are combined to investigate a possible direct connection between gaze and steering: Is there enough information in gaze direction that it could be used in isolation to steer through a series of waypoints? For this, we test steering models using waypoints supplied from human gaze data, as well as waypoints specified by optical features of the environment. Steering-by-gaze was modeled using a "pure-pursuit" controller (computing a circular trajectory toward a steering point), or a simple "proportional" controller (yaw-rate set proportional to the visual angle of the steering point). Both controllers produced successful steering when using human gaze data as the input. The models generalized using the same parameters across two scenarios: (a) steering through a slalom of three visible waypoints located within lane boundaries and (b) steering a series of connected S bends comprising visible waypoints without a visible road. While the trajectories on average broadly matched those generated by humans, the differences in individual trajectories were not captured by the models. We suggest that "looking where we are going" provides useful information and that this can often be adequate to guide steering. Capturing variation in human steering responses, however, likely requires more sophisticated models or additional sensory information.
    MeSH term(s) Humans ; Fixation, Ocular ; Eye Movements ; Automobile Driving ; Vision, Ocular ; Psychomotor Performance/physiology
    Language English
    Publishing date 2023-07-21
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2106064-2
    ISSN 1534-7362 ; 1534-7362
    ISSN (online) 1534-7362
    ISSN 1534-7362
    DOI 10.1167/jov.23.7.12
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Analyzing symptom data in indoor air questionnaires for primary schools.

    Ung-Lanki, S / Lampi, J / Pekkanen, J

    Indoor air

    2017  Volume 27, Issue 5, Page(s) 900–908

    Abstract: Questionnaires on symptoms and perceived quality of indoor environment are used to assess indoor environment problems, but mainly among adults. The aim of this article was to explore best ways to analyze and report such symptom data, as part of a project ...

    Abstract Questionnaires on symptoms and perceived quality of indoor environment are used to assess indoor environment problems, but mainly among adults. The aim of this article was to explore best ways to analyze and report such symptom data, as part of a project to develop a parent-administered indoor air questionnaire for primary school pupils. Indoor air questionnaire with 25 questions on child's symptoms in the last 4 weeks was sent to parents in five primary schools with indoor air problems and in five control schools. About 83% of parents (N=1470) in case schools and 82% (N=805) in control schools returned the questionnaire. In two schools, 351 (52%) parents answered the questionnaire twice with a 2-week interval. Based on prevalence of symptoms, their test-retest repeatability (ICC), and on principal component analysis (PCA), the number of symptoms was reduced to 17 and six symptoms scores were developed. Six variants of these six symptom scores were then formed and their ability to rank schools compared. Four symptom scores (respiratory, lower respiratory, eye, and general symptoms) analyzed dichotomized maintained sufficiently well the diversity of symptom data and captured the between-school differences in symptom prevalence, when compared to more complex and numerous scores.
    Language English
    Publishing date 2017-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 1081722-0
    ISSN 1600-0668 ; 0905-6947
    ISSN (online) 1600-0668
    ISSN 0905-6947
    DOI 10.1111/ina.12378
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book ; Thesis: Coronary heart disease during a 25-year [twenty-five year] follow-up

    Pekkanen, Juha

    risk factors and their secular trends in the Finnish cohorts of the seven countries study

    (Lääkintöhallituksen tutkimuksia ; 45)

    1987  

    Title variant Coronary heart disease during a 25-year follow-up
    Series title Lääkintöhallituksen tutkimuksia ; 45
    Collection
    Keywords Coronary Disease / epidemiology / Finland ; Follow-Up Studies ; Risk Factors
    Size 135, 5 S. : graph. Darst.
    Publishing country Finland
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Helsinki, Univ., Diss., 1987
    HBZ-ID HT003296758
    ISBN 951-860-616-1 ; 978-951-860-616-4
    Database Catalogue ZB MED Medicine, Health

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  8. Article: Persistence of chronic cough in a community-based population.

    Lätti, Anne M / Pekkanen, Juha / Koskela, Heikki O

    ERJ open research

    2020  Volume 6, Issue 2

    Abstract: Chronic cough causes significant impairment in the quality of life and is often immune to treatment. Previous studies about its persistence have focused on patients managed in special cough clinics. Little is known about the persistence of chronic cough ... ...

    Abstract Chronic cough causes significant impairment in the quality of life and is often immune to treatment. Previous studies about its persistence have focused on patients managed in special cough clinics. Little is known about the persistence of chronic cough in unselected populations. In this prospective follow-up study, we investigated factors that predict the persistence of cough at 12-month follow-up in a community-based study of subjects with chronic cough. The first e-mail survey in 2017 included a questionnaire about current cough and its risk factors. The 264 subjects who reported chronic cough were sent a follow-up questionnaire 12 months later. The response rate was 77.7% (205 subjects), of whom 165 subjects (80.5%) still had cough in 2018. In multivariate analysis, the following baseline factors predicted the persistence of cough at 12 months; gastro-oesophageal reflux disease (adjusted OR (aOR) 5.02 (95% CI 1.10-22.83)), presence of a chemical trigger (aOR 2.88 (95% CI (1.20-7.00)), duration of cough more than 1 year (aOR 2.80 (95% CI 1.27-6.22)), frequent somatic symptoms (aOR 1.31 (95% CI 1.07-1.59)), and low number of family members (aOR 0.71 (95% CI 0.52-0.98)). In conclusion, most patients with chronic cough still suffer from cough 1 year later. The presence of gastro-oesophageal reflux disease is the main predictor for the persistence of cough.
    Language English
    Publishing date 2020-05-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2827830-6
    ISSN 2312-0541
    ISSN 2312-0541
    DOI 10.1183/23120541.00229-2019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Letter to the Study by Hyvönen et al. on Moisture Damage and MCS.

    Pekkanen, Juha / Karjalainen, Jussi / Lampi, Jussi

    Safety and health at work

    2020  Volume 11, Issue 3, Page(s) 378–379

    Abstract: Due to the significant methodological problems in the empirical part of the paper and the very selective literature review, the conclusions of the paper are mostly unsupported. ...

    Abstract Due to the significant methodological problems in the empirical part of the paper and the very selective literature review, the conclusions of the paper are mostly unsupported.
    Language English
    Publishing date 2020-06-12
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2592798-X
    ISSN 2093-7997 ; 2093-7911
    ISSN (online) 2093-7997
    ISSN 2093-7911
    DOI 10.1016/j.shaw.2020.05.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Dampness and student-reported social climate: two multilevel mediation models.

    Finell, Eerika / Tolvanen, Asko / Pekkanen, Juha / Ståhl, Timo / Luopa, Pauliina

    Environmental health : a global access science source

    2021  Volume 20, Issue 1, Page(s) 30

    Abstract: Background: Little previous research has analysed the relationship between schools' indoor air problems and schools' social climate. In this study, we analysed a) whether observed mould and dampness in a school building relates to students' perceptions ... ...

    Abstract Background: Little previous research has analysed the relationship between schools' indoor air problems and schools' social climate. In this study, we analysed a) whether observed mould and dampness in a school building relates to students' perceptions of school climate (i.e. teacher-student relationships and class spirit) and b) whether reported subjective indoor air quality (IAQ) at the school level mediates this relationship.
    Methods: The data analysed was created by merging two nationwide data sets: survey data from students, including information on subjective IAQ (N = 25,101 students), and data from schools, including information on mould and dampness in school buildings (N = 222). The data was analysed using multilevel mediational models.
    Results: After the background variables were adjusted, schools' observed mould and dampness was not significantly related to neither student-perceived teacher-student relationships nor class spirit. However, our mediational models showed that there were significant indirect effects from schools' observed mould and dampness to outcome variables via school-level subjective IAQ: a) in schools with mould and dampness, students reported significantly poorer subjective IAQ (standardised β = 0.34, p < 0.001) than in schools without; b) the worse the subjective IAQ at school level, the worse the student-reported teacher-student relationships (β = 0.31, p = 0.001) and class spirit (β = 0.25, p = 0.006).
    Conclusions: Problems in a school's indoor environment may impair the school's social climate to the degree that such problems decrease the school's perceived IAQ.
    MeSH term(s) Adolescent ; Air Pollution, Indoor ; Female ; Fungi ; Humans ; Humidity ; Male ; Multilevel Analysis ; Negotiating ; Schools ; Social Conditions ; Students/psychology
    Language English
    Publishing date 2021-03-19
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2092232-2
    ISSN 1476-069X ; 1476-069X
    ISSN (online) 1476-069X
    ISSN 1476-069X
    DOI 10.1186/s12940-021-00710-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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