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  1. Article: Continuous ambulatory peritoneal dialysis and automated peritoneal dialysis: are there differences in outcome?

    Dell'Aquila, R / Berlingò, G / Pellanda, M V / Contestabile, A

    Contributions to nephrology

    2009  Volume 163, Page(s) 292–299

    Abstract: The proportion of peritoneal dialysis (PD) patients on automated peritoneal dialysis (APD) has been steadily increasing over the past decade. In the US, the percentage of PD patients on APD has steadily risen from 9% in 1993 to 54% in 2000. In continuous ...

    Abstract The proportion of peritoneal dialysis (PD) patients on automated peritoneal dialysis (APD) has been steadily increasing over the past decade. In the US, the percentage of PD patients on APD has steadily risen from 9% in 1993 to 54% in 2000. In continuous ambulatory peritoneal dialysis (CAPD), PD exchanges are performed manually, while in APD a mechanical device to assist the delivery and drainage of dialysate is employed. In CAPD, the patient or carer must perform at least 4-5 exchanges everyday. Many problems inherent to CAPD such as lack of sustained patient motivation over long periods of time, technique failure and recurrent peritonitis, led to a resurgence of interest in APD. APD has been reported to have several advantages over CAPD including lower incidence of peritonitis, better small solute clearances and reduced incidences of hernias. APD, especially in the form of nocturnal intermittent peritoneal dialysis (NIPD), has also been suggested to offer a number of psychosocial and physical benefits over CAPD mainly on account of fewer connections and being free of fluid in the abdomen during daytime. Such benefits relate to better dialysis acceptability for workers, school students or carers of elderly patients, pain and body image difficulties and reduced intra-abdominal pressures. APD is also considered to be more suitable form of PD in patients who have a rapid rate of solute transfer across their peritoneal membrane (high transporters) because of the ability to perform rapid frequent exchanges with shorter dwell times. It is not still clear if, with APD when compared to CAPD, a more rapid decline in residual renal function is present. Since the direct costs of APD are over 20% greater than CAPD and given this increasing trend towards greater use of APD, the aim of this paper is to understand if there are really differences in terms of quality of life and outcomes in favor of APD when compared to CAPD.
    MeSH term(s) Chronic Disease ; Humans ; Kidney Diseases/therapy ; Peritoneal Dialysis/methods ; Peritoneal Dialysis, Continuous Ambulatory/methods ; Peritonitis/epidemiology ; Quality of Life ; Risk Factors ; Treatment Outcome
    Language English
    Publishing date 2009-06-03
    Publishing country Switzerland
    Document type Comparative Study ; Journal Article
    ISSN 0302-5144
    ISSN 0302-5144
    DOI 10.1159/000223813
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Abdominal pain in a CAPD patient treated with intravenous adriamycin: a chemical peritonitis?

    Fabris, A / Contestabile, A / Pellanda, M V / Gardin, C / De Vivo, E / Guerini, A

    Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis

    2000  Volume 20, Issue 1, Page(s) 93–94

    MeSH term(s) Abdominal Pain/chemically induced ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/adverse effects ; Breast Neoplasms/drug therapy ; Doxorubicin/administration & dosage ; Doxorubicin/adverse effects ; Female ; Humans ; Injections, Intravenous ; Middle Aged ; Peritoneal Dialysis, Continuous Ambulatory ; Peritonitis/chemically induced
    Chemical Substances Antineoplastic Agents ; Doxorubicin (80168379AG)
    Language English
    Publishing date 2000-01
    Publishing country United States
    Document type Case Reports ; Letter
    ZDB-ID 645010-6
    ISSN 0896-8608
    ISSN 0896-8608
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Prune-belly syndrome in a geriatric patient.

    Fabris, A / Pellanda, M V / Gardin, C / Contestabile, A / De Vivo, E

    Nephron

    2000  Volume 86, Issue 2, Page(s) 251–252

    MeSH term(s) Aged ; Diuresis ; Humans ; Kidney Function Tests ; Male ; Prune Belly Syndrome/diagnosis ; Prune Belly Syndrome/physiopathology
    Language English
    Publishing date 2000-10
    Publishing country Switzerland
    Document type Case Reports ; Letter
    ZDB-ID 207121-6
    ISSN 1423-0186 ; 2235-3186 ; 1660-8151 ; 0028-2766
    ISSN (online) 1423-0186 ; 2235-3186
    ISSN 1660-8151 ; 0028-2766
    DOI 10.1159/000045775
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Vaccinazione anti epatite B in un servizio di emodialisi.

    Faggion, G / Pellanda, M V / Martimbianco, L

    Minerva urologica e nefrologica = The Italian journal of urology and nephrology

    1987  Volume 39, Issue 4, Page(s) 429–432

    Title translation Anti-hepatitis B vaccination in a hemodialysis service.
    MeSH term(s) Female ; Hepatitis B/immunology ; Hepatitis B/prevention & control ; Hepatitis B Surface Antigens/immunology ; Hepatitis B Vaccines ; Humans ; Male ; Renal Dialysis ; Viral Hepatitis Vaccines/administration & dosage ; Viral Hepatitis Vaccines/immunology
    Chemical Substances Hepatitis B Surface Antigens ; Hepatitis B Vaccines ; Viral Hepatitis Vaccines
    Language Italian
    Publishing date 1987-10
    Publishing country Italy
    Document type English Abstract ; Journal Article
    ZDB-ID 632505-1
    ISSN 1827-1758 ; 0393-2249 ; 0026-4989
    ISSN (online) 1827-1758
    ISSN 0393-2249 ; 0026-4989
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Pharmacokinetics of antifungal agents.

    Fabris, A / Pellanda, M V / Gardin, C / Contestabile, A / Bolzonella, R

    Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis

    1993  Volume 13 Suppl 2, Page(s) S380–2

    Abstract: The authors have evaluated the pharmacokinetics of four antifungal agents used in the therapy of fungal peritonitis. Amphotericin B (Amph B) poorly diffuses from blood into peritoneal fluid, which intraperitoneal administration induces severe abdominal ... ...

    Abstract The authors have evaluated the pharmacokinetics of four antifungal agents used in the therapy of fungal peritonitis. Amphotericin B (Amph B) poorly diffuses from blood into peritoneal fluid, which intraperitoneal administration induces severe abdominal pain. 5-Fluorocytosine (5FC) easily crosses peritoneum, but resistance may appear when the drug is used alone. Ketoconazole (K) poorly penetrates into peritoneal fluid, while Fluconazole (F), used per os or intraperitoneally, shows a good antifungal activity both in serum and in the peritoneal fluid. In conclusion, from a pharmacokinetic point of view, all the antifungal agents examined, perhaps with the exception of F, do not offer, when used alone, sufficient guarantees in curing peritonitis. Therefore, for treating fungal infections in CAPD, drug combinations such as AmphB + 5FC, K + 5FC or 5FC+F have to be used.
    MeSH term(s) Amphotericin B/pharmacokinetics ; Antifungal Agents/pharmacokinetics ; Fluconazole/pharmacokinetics ; Flucytosine/pharmacokinetics ; Humans ; Ketoconazole/pharmacokinetics ; Mycoses/drug therapy ; Mycoses/etiology ; Peritoneal Dialysis, Continuous Ambulatory/adverse effects ; Peritonitis/drug therapy ; Peritonitis/etiology
    Chemical Substances Antifungal Agents ; Amphotericin B (7XU7A7DROE) ; Fluconazole (8VZV102JFY) ; Flucytosine (D83282DT06) ; Ketoconazole (R9400W927I)
    Language English
    Publishing date 1993
    Publishing country United States
    Document type Journal Article
    ZDB-ID 645010-6
    ISSN 0896-8608
    ISSN 0896-8608
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Fluctuation of vasopressin secretion in chronic hypernatremia.

    Fabris, A / Ronco, C / Pellanda, M V / Gardin, C / Chiaramonte, S / Feriani, M / La Greca, G

    Nephron

    1990  Volume 54, Issue 3, Page(s) 245–248

    Abstract: Herein we will describe a case of chronic hypernatremic-hyperosmolar syndrome with cerebral localization of systemic sarcoidosis. Several determinations of plasma arginine vasopressin (p-AVP) at various plasma sodium levels were carried out in this ... ...

    Abstract Herein we will describe a case of chronic hypernatremic-hyperosmolar syndrome with cerebral localization of systemic sarcoidosis. Several determinations of plasma arginine vasopressin (p-AVP) at various plasma sodium levels were carried out in this patient. During the study p-AVP values varied between 2.6 and 9.5 pg/ml. A high percentage of them was related to plasma osmolality, pointing out that p-AVP secretion was osmotically mediated. This behavior is in contrast with the tendency of hypernatremic patients previously reported in the literature, in whom p-AVP values were inappropriately low for the corresponding degree of plasma osmolality, suggesting that vasopressin secretion was not influenced by osmotic stimulation. Furthermore, our case, unlike those previously described, showed high values of urinary osmolality. In conclusion, our patient represents, in essence, the 'middle' of the spectrum of the hypodipsic-hypernatremic syndrome, because she is to be inserted between the majority of patients who have little or no osmotically mediated AVP release and the case of a child, recently described, who had completely normal AVP secretion.
    MeSH term(s) Arginine Vasopressin/secretion ; Brain Diseases/complications ; Brain Diseases/physiopathology ; Chronic Disease ; Female ; Humans ; Hypernatremia/complications ; Hypernatremia/physiopathology ; Middle Aged ; Osmolar Concentration ; Sarcoidosis/complications ; Sarcoidosis/physiopathology ; Syndrome ; Thirst/physiology ; Vasopressins/secretion
    Chemical Substances Vasopressins (11000-17-2) ; Arginine Vasopressin (113-79-1)
    Language English
    Publishing date 1990
    Publishing country Switzerland
    Document type Case Reports ; Journal Article
    ZDB-ID 207121-6
    ISSN 1423-0186 ; 2235-3186 ; 1660-8151 ; 0028-2766
    ISSN (online) 1423-0186 ; 2235-3186
    ISSN 1660-8151 ; 0028-2766
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Fluctuation of Vasopressin Secretion in Chronic Hypernatremia

    Fabris, A. / Ronco, C. / Pellanda, M. V. / Gardin, C. / Chiaramonte, S. / Feriani, M. / La Greca, G.

    Nephron

    1990  Volume 54, Issue 3, Page(s) 245–248

    Abstract: Herein we will describe a case of chronic hypernatremic-hyperosmolar syndrome with cerebral localization of systemic sarcoidosis. Several determinations of plasma arginine vasopressin (p-AVP) at various plasma sodium levels were carried out in this ... ...

    Abstract Herein we will describe a case of chronic hypernatremic-hyperosmolar syndrome with cerebral localization of systemic sarcoidosis. Several determinations of plasma arginine vasopressin (p-AVP) at various plasma sodium levels were carried out in this patient. During the study p-AVP values varied between 2.6 and 9.5 pg/ml. A high percentage of them was related to plasma osmolality, pointing out that p-AVP secretion was osmotically mediated. This behavior is in contrast with the tendency of hypernatremic patients previously reported in the literature, in whom p-AVP values were inappropriately low for the corresponding degree of plasma osmolality, suggesting that vasopressin secretion was not influenced by osmotic stimulation. Furthermore, our case, unlike those previously described, showed high values of urinary osmolality. In conclusion, our patient represents, in essence, the ‘middle’ of the spectrum of the hypodipsic-hypernatremic syndrome, because she is to be inserted between the majority of patients who have little or no osmotically mediated AVP release and the case of a child, recently described, who had completely normal AVP secretion.
    Keywords Chronic hypernatremia ; Hypo-adipsia ; Plasma arginine vasopressin ; Plasma hyperosmolality
    Language English
    Publisher S. Karger AG
    Publishing place Basel
    Publishing country Switzerland
    Document type Article ; Online
    ZDB-ID 207121-6
    ISSN 1423-0186 ; 0028-2766 ; 1660-8151 ; 0028-2766 ; 1660-8151
    ISSN (online) 1423-0186
    ISSN 0028-2766 ; 1660-8151
    DOI 10.1159/000185863
    Database Karger publisher's database

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  8. Article: The importance of ultrafiltration on acid-base status in a dialysis population.

    Fabris, A / LaGreca, G / Chiaramonte, S / Feriani, M / Brendolan, A / Bragantini, L / Dell'Aquila, R / Pellanda, M V / Crepaldi, C / Ronco, C

    ASAIO transactions

    1988  Volume 34, Issue 3, Page(s) 200–201

    Abstract: The amount of fluid withdrawn by ultrafiltration in a dialysis session plays an important role in regulating the acid-base status of patients. It has been previously demonstrated that an interdialytic weight gain of 3 kilograms requires the removal of 3 ... ...

    Abstract The amount of fluid withdrawn by ultrafiltration in a dialysis session plays an important role in regulating the acid-base status of patients. It has been previously demonstrated that an interdialytic weight gain of 3 kilograms requires the removal of 3 liters, mostly of extracellular fluid, which may contain 60-70 mMols of bicarbonate. Such losses require an increase in the buffer mass transfer to achieve a good buffer balance. The importance of interdialytic weight gain (IWG) on acid-base status was evaluated in two significantly different periods. In the period where the IWG was lower, predialytic pH and HCO3 were significantly higher than in the alternate period. Since dialysis schedule, dialysate buffer, daily protein intake and given medications did not differ during the two periods, we conclude that a reduced ultrafiltration due to less weight gain betters predialytic acid-base status.
    MeSH term(s) Acid-Base Equilibrium ; Bicarbonates/blood ; Body Weight ; Carbon Dioxide/blood ; Humans ; Hydrogen-Ion Concentration ; Renal Dialysis ; Ultrafiltration
    Chemical Substances Bicarbonates ; Carbon Dioxide (142M471B3J)
    Language English
    Publishing date 1988-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639129-1
    ISSN 0889-7190
    ISSN 0889-7190
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Total solute extraction versus clearance in the evaluation of standard and short hemodialysis.

    Fabris, A / La Greca, G / Chiaramonte, S / Feriani, M / Brendolan, A / Bragantini, L / Milan, M / Pellanda, M V / Crepaldi, C / Ronco, C

    ASAIO transactions

    1988  Volume 34, Issue 3, Page(s) 627–629

    Abstract: The authors compared the efficiency of standard HD (t = 240 minutes, Qb = 300 ml/min, Qd = 500 ml/min) with short HD (t = 150 minutes, Qb = 500 ml/min, Qd = 700 ml/min). The study was carried out in 11 patients in two sequential dialysis sessions, ... ...

    Abstract The authors compared the efficiency of standard HD (t = 240 minutes, Qb = 300 ml/min, Qd = 500 ml/min) with short HD (t = 150 minutes, Qb = 500 ml/min, Qd = 700 ml/min). The study was carried out in 11 patients in two sequential dialysis sessions, utilizing the same high surface area hollow fiber dialyzers, after a 2 day interdialytic period. With short HD, as expected, the clearance (Cl) of BUN, creatinine (Cr), and phosphates (P) was significantly higher than in standard HD:Cl BUN = 331 vs. 225, Cl Cr = 286 vs. 193, and Cl P = 231 vs. 176 ml/min. No significant difference in the total BUN extraction (measured on the total amount of exhausted dialysate) was found between the two techniques. As to Cr and P, despite higher Cl in short HD, the total extractions were significantly lower. In conclusion, in the evaluation of short HD efficiency, instantaneous Cl can be adequate for small molecules, while for larger solutes, other parameters, such as total extraction, must be considered.
    MeSH term(s) Blood Flow Velocity ; Blood Urea Nitrogen ; Creatinine/blood ; Dialysis Solutions/analysis ; Hemodialysis Solutions/analysis ; Hemodialysis Solutions/metabolism ; Humans ; Phosphates/blood ; Renal Dialysis/methods ; Time Factors
    Chemical Substances Dialysis Solutions ; Hemodialysis Solutions ; Phosphates ; Creatinine (AYI8EX34EU)
    Language English
    Publishing date 1988-07
    Publishing country United States
    Document type Comparative Study ; Journal Article
    ZDB-ID 639129-1
    ISSN 0889-7190
    ISSN 0889-7190
    Database MEDical Literature Analysis and Retrieval System OnLINE

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