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  1. Article ; Online: Author's reply: "Assessing ChatGPT and perplexity AI performance".

    Pellegrino, Raffaele / Gravina, Antonietta Gerarda

    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

    2024  

    Abstract: None. ...

    Abstract None.
    Language English
    Publishing date 2024-04-20
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1459373-7
    ISSN 1878-3562 ; 1125-8055
    ISSN (online) 1878-3562
    ISSN 1125-8055
    DOI 10.1016/j.dld.2024.04.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Emerging space for non-polyethene-glycol bowel preparations in inflammatory bowel disease-related colonoscopy: Veering toward better adherence and palatability.

    Pellegrino, Raffaele / Gravina, Antonietta Gerarda

    World journal of gastroenterology

    2023  Volume 29, Issue 46, Page(s) 6022–6027

    Abstract: Patients with inflammatory bowel diseases (IBDs) require repeated endoscopic evaluations over time by colonoscopy to weigh disease activity but also for different and additional indications ( ...

    Abstract Patients with inflammatory bowel diseases (IBDs) require repeated endoscopic evaluations over time by colonoscopy to weigh disease activity but also for different and additional indications (
    MeSH term(s) Humans ; Cathartics/adverse effects ; Polyethylene Glycols/adverse effects ; Colonoscopy/methods ; Inflammatory Bowel Diseases/drug therapy
    Chemical Substances Cathartics ; Polyethylene Glycols (3WJQ0SDW1A)
    Language English
    Publishing date 2023-12-07
    Publishing country United States
    Document type Editorial
    ZDB-ID 2185929-2
    ISSN 2219-2840 ; 1007-9327
    ISSN (online) 2219-2840
    ISSN 1007-9327
    DOI 10.3748/wjg.v29.i46.6022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Editorial: Challenges in inflammatory bowel disease: current, future and unmet needs, volume II.

    Gravina, Antonietta Gerarda / Pellegrino, Raffaele / Bodini, Giorgia

    Frontiers in medicine

    2023  Volume 10, Page(s) 1326126

    Language English
    Publishing date 2023-11-13
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2023.1326126
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Charting new AI education in gastroenterology: Cross-sectional evaluation of ChatGPT and perplexity AI in medical residency exam.

    Gravina, Antonietta Gerarda / Pellegrino, Raffaele / Palladino, Giovanna / Imperio, Giuseppe / Ventura, Andrea / Federico, Alessandro

    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

    2024  

    Abstract: Background: Conversational chatbots, fueled by large language models, spark debate over their potential in education and medical career exams. There is debate in the literature about the scientific integrity of the outputs produced by these chatbots.: ...

    Abstract Background: Conversational chatbots, fueled by large language models, spark debate over their potential in education and medical career exams. There is debate in the literature about the scientific integrity of the outputs produced by these chatbots.
    Aims: This study evaluates ChatGPT 3.5 and Perplexity AI's cross-sectional performance in responding to questions from the 2023 Italian national residency admission exam (SSM23), comparing results and chatbots' concordance with previous years SSMs.
    Methods: Gastroenterology-related SSM23 questions were input into ChatGPT 3.5 and Perplexity AI, evaluating their performance in correct responses and total scores. This process was repeated with questions from the three preceding years. Additionally, chatbot concordance was assessed using Cohen's method.
    Results: In SSM23, ChatGPT 3.5 outperforms Perplexity AI with 94.11% correct responses, demonstrating consistency across years. Concordance weakened in 2023 (κ=0.203, P = 0.148), but ChatGPT consistently maintains a high standard compared to Perplexity AI.
    Conclusion: ChatGPT 3.5 and Perplexity AI exhibit promise in addressing gastroenterological queries, emphasizing potential educational roles. However, their variable performance mandates cautious use as supplementary tools alongside conventional study methods. Clear guidelines are crucial for educators to balance traditional approaches and innovative systems, enhancing educational standards.
    Language English
    Publishing date 2024-03-18
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1459373-7
    ISSN 1878-3562 ; 1125-8055
    ISSN (online) 1878-3562
    ISSN 1125-8055
    DOI 10.1016/j.dld.2024.02.019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Endoscopic calcium electroporation for unfit-for-surgery bleeding colorectal cancer: the dawn of a new treatment?

    Pellegrino, Raffaele / Nacca, Valeria / Paragliola, Fernando / Martinelli, Erika / Federico, Alessandro / Gravina, Antonietta G

    Minerva medica

    2024  

    Language English
    Publishing date 2024-04-10
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 123586-2
    ISSN 1827-1669 ; 0026-4806
    ISSN (online) 1827-1669
    ISSN 0026-4806
    DOI 10.23736/S0026-4806.24.09270-X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Editorial: Challenges in Inflammatory Bowel Disease: Current, Future and Unmet Needs.

    Gravina, Antonietta Gerarda / Pellegrino, Raffaele / Zingone, Fabiana

    Frontiers in medicine

    2022  Volume 9, Page(s) 979535

    Language English
    Publishing date 2022-07-18
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2022.979535
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Considering a Janus kinase inhibitor in patients with concomitant ulcerative colitis and hidradenitis suppurativa/acne inversa: is it really a gamble? Hints from a case report.

    Pellegrino, Raffaele / Palladino, Giovanna / Imperio, Giuseppe / Cipullo, Marina / Federico, Alessandro / Gravina, Antonietta G

    Minerva medica

    2023  

    Language English
    Publishing date 2023-09-21
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 123586-2
    ISSN 1827-1669 ; 0026-4806
    ISSN (online) 1827-1669
    ISSN 0026-4806
    DOI 10.23736/S0026-4806.23.08867-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: May ChatGPT be a tool producing medical information for common inflammatory bowel disease patients' questions? An evidence-controlled analysis.

    Gravina, Antonietta Gerarda / Pellegrino, Raffaele / Cipullo, Marina / Palladino, Giovanna / Imperio, Giuseppe / Ventura, Andrea / Auletta, Salvatore / Ciamarra, Paola / Federico, Alessandro

    World journal of gastroenterology

    2024  Volume 30, Issue 1, Page(s) 17–33

    Abstract: Artificial intelligence is increasingly entering everyday healthcare. Large language model (LLM) systems such as Chat Generative Pre-trained Transformer (ChatGPT) have become potentially accessible to everyone, including patients with inflammatory bowel ... ...

    Abstract Artificial intelligence is increasingly entering everyday healthcare. Large language model (LLM) systems such as Chat Generative Pre-trained Transformer (ChatGPT) have become potentially accessible to everyone, including patients with inflammatory bowel diseases (IBD). However, significant ethical issues and pitfalls exist in innovative LLM tools. The hype generated by such systems may lead to unweighted patient trust in these systems. Therefore, it is necessary to understand whether LLMs (trendy ones, such as ChatGPT) can produce plausible medical information (MI) for patients. This review examined ChatGPT's potential to provide MI regarding questions commonly addressed by patients with IBD to their gastroenterologists. From the review of the outputs provided by ChatGPT, this tool showed some attractive potential while having significant limitations in updating and detailing information and providing inaccurate information in some cases. Further studies and refinement of the ChatGPT, possibly aligning the outputs with the leading medical evidence provided by reliable databases, are needed.
    MeSH term(s) Humans ; Artificial Intelligence ; Databases, Factual ; Gastroenterologists ; Inflammatory Bowel Diseases ; Language
    Language English
    Publishing date 2024-01-25
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2185929-2
    ISSN 2219-2840 ; 1007-9327
    ISSN (online) 2219-2840
    ISSN 1007-9327
    DOI 10.3748/wjg.v30.i1.17
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: The JAK-STAT Pathway as a Therapeutic Strategy in Cancer Patients with Immune Checkpoint Inhibitor-Induced Colitis: A Narrative Review.

    Gravina, Antonietta Gerarda / Pellegrino, Raffaele / Esposito, Alfonso / Cipullo, Marina / Romeo, Mario / Palladino, Giovanna / Iodice, Patrizia / Federico, Alessandro / Troiani, Teresa

    Cancers

    2024  Volume 16, Issue 3

    Abstract: Immunotherapy has emerged as a pivotal component in the treatment of various malignancies, encompassing lung, skin, gastrointestinal, and head and neck cancers. The foundation of this therapeutic approach lies in immune checkpoint inhibitors (ICI). While ...

    Abstract Immunotherapy has emerged as a pivotal component in the treatment of various malignancies, encompassing lung, skin, gastrointestinal, and head and neck cancers. The foundation of this therapeutic approach lies in immune checkpoint inhibitors (ICI). While ICIs have demonstrated remarkable efficacy in impeding the neoplastic progression of these tumours, their use may give rise to substantial toxicity, notably in the gastrointestinal domain, where ICI colitis constitutes a significant aspect. The optimal positioning of Janus kinase (JAK)-signal transducer and activator of transcription (STAT) pathway inhibitors in the therapeutic management of ICI colitis remains unclear. Numerous reports have highlighted notable improvements in ICI colitis through the application of pan-JAK-STAT inhibitors, with tofacitinib, in particular, reporting evident clinical remission of colitis. The precise mechanism by which JAK-STAT inhibitors may impact the pathogenetic process of ICI colitis remains inadequately understood. However, there is speculation regarding their potential role in modulating memory resident CD8
    Language English
    Publishing date 2024-01-31
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers16030611
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The use of bicarbonate-sulphate-calcium-magnesium and sodium-low drinkable water improves functional gastrointestinal symptoms in patients with non-alcoholic fatty liver disease: A prospective study

    Gravina, Antonietta Gerarda / Pellegrino, Raffaele / Romeo, Mario / Ventriglia, Lorenzo / Scognamiglio, Flavia / Tuccillo, Concetta / Loguercio, Carmelina / Federico, Alessandro

    European Society for Clinical Nutrition and Metabolism Clinical Nutrition ESPEN. 2023 Oct., v. 57 p.281-287

    2023  

    Abstract: Non-alcoholic fatty liver disease is increasingly gaining epidemiological ground in liver diseases. Among the proposed non-pharmacologic interventions, dietary interventions have been widely used. Several patients suffering from it complain of ... ...

    Abstract Non-alcoholic fatty liver disease is increasingly gaining epidemiological ground in liver diseases. Among the proposed non-pharmacologic interventions, dietary interventions have been widely used. Several patients suffering from it complain of gastrointestinal symptoms unrelated to organic gastrointestinal tract disease. However, the role of drinking water quality modifications in this regard has not been investigated in depth. Patients with upper or lower functional gastrointestinal symptoms were enrolled and divided into groups based on bright liver ultrasound relief's presence (SP) or absence (NSP). These patients were asked to drink bicarbonate-sulphate-calcium-magnesium and sodium-low drinkable water (Fonte Essenziale ®) for six months. Participants were assessed at baseline (T0), at the end of six months of drinking water intake (T6), and after an additional six months of washout (T12) by questionnaires designed to evaluate lower and upper gastrointestinal symptoms (Leeds dyspepsia score, short form) severity and frequency. A total of 61 patients were enrolled. In the SP population, the severity of lower gastrointestinal symptoms improved between T0–T6 (Z: −2.437; ES: 0.312) and worsened after the water washout (Z: −2.492; ES: 0.319). The same was for the Leeds score severity sub score in T0–T6 (Z: −2.850; ES: 0.364) and T6–T12 (Z: −2.921; ES: 0.374). These improvements seem unrelated to the severity of liver steatosis at baseline. Furthermore, no safety issues were recorded while taking the water nor during the six-month follow-up afterwards. Regular six-month intake of 400 mL of Fonte Essenziale® water was associated, in the absence of dietary regimen modifications, with an improvement in some qualitative and quantitative features of upper and lower functional gastrointestinal symptoms in both an SP and NSP sample.
    Keywords clinical nutrition ; digestive tract ; drinking water ; fatty liver ; gastrointestinal system ; indigestion ; liver ; prospective studies ; ultrasonics ; water quality ; Fatty liver disease ; Drinkable water ; Gastrointestinal symptoms ; Gut–liver axis
    Language English
    Dates of publication 2023-10
    Size p. 281-287.
    Publishing place Elsevier Ltd
    Document type Article ; Online
    ISSN 2405-4577
    DOI 10.1016/j.clnesp.2023.07.008
    Database NAL-Catalogue (AGRICOLA)

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