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  1. Article ; Online: A new minimal-invasive approach for total hip replacement in sheep.

    Melcher, Carolin / Gottschalk, Oliver / Mazoochian, Farhad / Pieper, Korbinian / Wegener, Veronika / Pellengahr, Christoph Schulze / Teske, Wolfram / Wegener, Bernd

    Technology and health care : official journal of the European Society for Engineering and Medicine

    2022  Volume 31, Issue 5, Page(s) 1867–1874

    Abstract: Background: Over the last 50 years arthroplasty became the gold-standard treatment for disabling conditions of the coxofemoral joint. Variations of anterior, lateral, and dorsal incision have been applied, but as each approach requires the incision and ... ...

    Abstract Background: Over the last 50 years arthroplasty became the gold-standard treatment for disabling conditions of the coxofemoral joint. Variations of anterior, lateral, and dorsal incision have been applied, but as each approach requires the incision and reflection of various muscles to gain adequate exposure of the joint results are still controversial.
    Objective: The purpose of this study was to develop a minimal-invasive, tissue-sparing approach in sheep with reduced risks in animal testing.
    Methods: 12 mature sheep underwent hip surgery as part of a study to evaluate a hip resurfacing system. In line with the preliminary cadaveric tests a modified, minimal-invasive, musclepreserving surgical approach was sought after.
    Results: We developed a surgical approach to the coxofemoral joint in sheep using only blunt tissue dissection after skin incision without any limitations in joint exposure or increased blood loss/duration of surgery.
    Conclusion: Even though limitations occur and femoral orientation in sheep differs from man, joint forces have similar relative directions to the bone with similar bony and vascular anatomy. Therefore, this minimal-invasive muscle preserving approach might be a safe and comparable alternative in still inevitable animal testing.
    MeSH term(s) Humans ; Animals ; Sheep ; Arthroplasty, Replacement, Hip/methods ; Minimally Invasive Surgical Procedures/methods ; Hip Joint ; Muscles/surgery ; Treatment Outcome
    Language English
    Publishing date 2022-11-15
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1159961-3
    ISSN 1878-7401 ; 0928-7329
    ISSN (online) 1878-7401
    ISSN 0928-7329
    DOI 10.3233/THC-220805
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3846: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Sympathetic dysfunction in long-term complex regional pain syndrome.

    Vogel, Tobias / Gradl, Georg / Ockert, Ben / Pellengahr, Christoph Schulze / Schürmann, Matthias

    The Clinical journal of pain

    2010  Volume 26, Issue 2, Page(s) 128–131

    Abstract: Objective: Malfunction of the sympathetic nervous system (SNS) is common in early complex regional pain syndrome type I (CRPS I). This study was designed to evaluate the function of the SNS in patients with chronic CRPS I and to correlate the obtained ... ...

    Abstract Objective: Malfunction of the sympathetic nervous system (SNS) is common in early complex regional pain syndrome type I (CRPS I). This study was designed to evaluate the function of the SNS in patients with chronic CRPS I and to correlate the obtained data with hand function measurements.
    Materials and methods: Thirty-two patients of both the sexes in whom the diagnosis of CRPS I of the upper extremity had been established for at least 3 years before they were included in the study. Besides a hand outcomes questionnaire [Michigan Hand Outcome Questionnaire, (MHQ)] the patients underwent a standardized testing of the peripheral sympathetic nervous system (pSNS) using laser Doppler flowmetry (LDF).
    Results: Mean time since initial diagnosis was 4.6+/-2.1 years. The mean MHQ score of the affected limb was 57.3+/-17 compared with 69.4+/-13.7 for the unaffected hand (P=0.002). Twenty patients (62.5%) still demonstrated pathologic results regarding the pSNS function (mean sympathetic reflex 0.18+/-0.11, normal range>0.38). We found no statistically significant correlation between pSNS function either with the clinical outcome as measured by MHQ (r=0.246; P=0.175), or with the level of pain (r=0.132; P=0.473).
    Conclusions: Even 5 years after the diagnosis of CRPS I of the upper extremity we detected significant impairments of the pSNS in nearly two thirds of our patients. Patients still have pain and present with a significant deterioration of their hand function in comparison with the not affected hand. In our study we could not identify any correlation between pSNS function and clinical outcome as measured by MHQ.
    MeSH term(s) Aged ; Autonomic Nervous System Diseases/etiology ; Female ; Functional Laterality ; Hand/physiopathology ; Hand Strength/physiology ; Humans ; Laser-Doppler Flowmetry ; Longitudinal Studies ; Male ; Middle Aged ; Pain Measurement/methods ; Reflex/physiology ; Reflex Sympathetic Dystrophy/complications ; Reflex Sympathetic Dystrophy/pathology ; Surveys and Questionnaires
    Language English
    Publishing date 2010-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632582-8
    ISSN 1536-5409 ; 0749-8047
    ISSN (online) 1536-5409
    ISSN 0749-8047
    DOI 10.1097/AJP.0b013e3181b5effc
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2078: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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