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  1. Article: Nasal Retainer 2.0: A New, Cheap, and Reliable Method to Prepare Custom-made Nostril Retainer for Nasal Reconstruction.

    Torresetti, Matteo / Pau, Alberto / Pelliccioni, Michele / Di Benedetto, Giovanni

    Plastic and reconstructive surgery. Global open

    2023  Volume 11, Issue 5, Page(s) e5023

    Abstract: Total nasal reconstruction always represents a challenge for the plastic surgeon, who must deal both with the reconstructive procedure and compliance of the patient. This kind of reconstruction often requires more than one step. Therefore, more prolonged ...

    Abstract Total nasal reconstruction always represents a challenge for the plastic surgeon, who must deal both with the reconstructive procedure and compliance of the patient. This kind of reconstruction often requires more than one step. Therefore, more prolonged and emphasized scarring than normal can occur, thus resulting in a higher risk of nostril stenosis. Although several nasal retainers have been described, traditional premade retainers could be poorly tolerated by patients and need to be adequately customized to improve patient compliance. Herein, the authors propose a new, cheap, and reliable method to prepare customized nasal retainers which can be used after every step of nasal reconstruction.
    Language English
    Publishing date 2023-05-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2851682-5
    ISSN 2169-7574 ; 2169-7574
    ISSN (online) 2169-7574
    ISSN 2169-7574
    DOI 10.1097/GOX.0000000000005023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: The impact of ICRP publication 92 on the conversion coefficients in use for cosmic ray dosimetry.

    Pelliccioni, M

    Radiation protection dosimetry

    2004  Volume 109, Issue 4, Page(s) 303–309

    Abstract: ICRP Publication 92 presents a proposal to achieve coherence between radiation weighting factors and quality factors. In particular, the radiation weighting factors for incident protons and neutrons have been revised and new values have been proposed. On ...

    Abstract ICRP Publication 92 presents a proposal to achieve coherence between radiation weighting factors and quality factors. In particular, the radiation weighting factors for incident protons and neutrons have been revised and new values have been proposed. On the basis of the proposed values, sets of conversion coefficients fluence-to-effective dose for protons and neutrons have been derived for the irradiation geometries of interest for cosmic ray dosimetry.
    MeSH term(s) Body Burden ; Cosmic Radiation ; Environmental Exposure/analysis ; Environmental Exposure/standards ; Humans ; International Cooperation ; Linear Energy Transfer ; Radiation Protection/methods ; Radiation Protection/standards ; Radiometry/instrumentation ; Radiometry/methods ; Radiometry/standards ; Relative Biological Effectiveness ; Societies, Scientific
    Language English
    Publishing date 2004
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 225912-6
    ISSN 1742-3406 ; 0144-8420
    ISSN (online) 1742-3406
    ISSN 0144-8420
    DOI 10.1093/rpd/nch306
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Radiation protection at Hadron therapy facilities.

    Pelliccioni, Maorizio

    Radiation protection dosimetry

    2011  Volume 146, Issue 4, Page(s) 407–413

    Abstract: The Italian National Centre for Oncological Hadrontherapy is currently under construction in Pavia. It is designed for the treatment of deep-seated tumours (up to a depth of 27 cm of water equivalent) with proton and C-ion beams as well as for both ... ...

    Abstract The Italian National Centre for Oncological Hadrontherapy is currently under construction in Pavia. It is designed for the treatment of deep-seated tumours (up to a depth of 27 cm of water equivalent) with proton and C-ion beams as well as for both clinical and radiobiological research. The particles will be accelerated by a 7-MeV u(-1) LINAC injector and a 400-MeV u(-1) synchrotron. In the first phase of the project, three treatment rooms will be in operation, equipped with four fixed beams, three horizontal and one vertical. The accelerators are currently undergoing commissioning. The main radiation protection problems encountered (shielding, activation, etc.) are hereby illustrated and discussed in relation to the constraints set by the Italian national authorities.
    MeSH term(s) Cancer Care Facilities ; Carbon Radioisotopes/therapeutic use ; Facility Design and Construction ; Humans ; Ions/chemistry ; Ions/therapeutic use ; Italy ; Neoplasms/radiotherapy ; Occupational Exposure/prevention & control ; Particle Accelerators/instrumentation ; Protons/therapeutic use ; Radiation Protection ; Synchrotrons/instrumentation
    Chemical Substances Carbon Radioisotopes ; Ions ; Protons
    Language English
    Publishing date 2011-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 225912-6
    ISSN 1742-3406 ; 0144-8420
    ISSN (online) 1742-3406
    ISSN 0144-8420
    DOI 10.1093/rpd/ncr242
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: The Role of Surgical Drainage on Complications after Sentinel Lymph Node Biopsy for Melanoma.

    Torresetti, Matteo / Scalise, Alessandro / Pelliccioni, Michele / Taddei, Francesco Mauro Junior / Di Benedetto, Giovanni

    Plastic and reconstructive surgery. Global open

    2022  Volume 10, Issue 11, Page(s) e4642

    Abstract: The real benefit of using drains for reducing the risk of complications in sentinel lymph node biopsy (SLNB) has not been investigated yet. We aimed to evaluate the role of drain after SLNB and to determine if a correlation exists between drains and ... ...

    Abstract The real benefit of using drains for reducing the risk of complications in sentinel lymph node biopsy (SLNB) has not been investigated yet. We aimed to evaluate the role of drain after SLNB and to determine if a correlation exists between drains and early complications.
    Methods: This is a retrospective study of patients who underwent SLNB for melanoma from 2016 to 2021. Patients were dichotomized into two groups according to the use of drain. The between-group comparison (drainage group versus no drainage group) was performed by using Mann-Whitney U test and chi-square test. A regression analysis was conducted to identify predictors of complications.
    Results: Of 218 individuals analyzed, 18 (8.4%) had postoperative complications. The most common complications were seroma (5.1%) and wound dehiscence (1.4%). The between-group analysis showed no significant differences in complication rate, whereas the operative time was significantly higher in the drainage group (
    Conclusions: Drainage use in SLNB prolonged hospital stays and duration of postoperative antibiotic therapy, thus resulting in higher costs. The preemptive use of drainage is suggested in selected settings of patients.
    Language English
    Publishing date 2022-11-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2851682-5
    ISSN 2169-7574 ; 2169-7574
    ISSN (online) 2169-7574
    ISSN 2169-7574
    DOI 10.1097/GOX.0000000000004642
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Some useful data for narrow beam dosimetry.

    Pelliccioni, M

    Radiation protection dosimetry

    2001  Volume 93, Issue 2, Page(s) 135–142

    Abstract: Organ doses and effective dose have been estimated in the case of an anthropomorphic mathematical model exposed to monoenergetic narrow beams of various types of incident radiation (photons, electrons, protons) and energies. The target organs considered ... ...

    Abstract Organ doses and effective dose have been estimated in the case of an anthropomorphic mathematical model exposed to monoenergetic narrow beams of various types of incident radiation (photons, electrons, protons) and energies. The target organs considered were right eye, thyroid and breast. Calculations have been carried out using the latest version of the Monte Carlo transport code FLUKA. The investigated energy range was extended from 5 MeV to 10 GeV. In the case of photons, incident energies in the region between 30 keV and 1 MeV were also considered. Preliminary results are presented.
    MeSH term(s) Breast/radiation effects ; Electrons ; Eye/radiation effects ; Humans ; Models, Theoretical ; Photons ; Protons ; Radiation Dosage ; Radiometry/methods ; Thyroid Gland/radiation effects
    Chemical Substances Protons
    Language English
    Publishing date 2001
    Publishing country England
    Document type Journal Article
    ZDB-ID 225912-6
    ISSN 1742-3406 ; 0144-8420
    ISSN (online) 1742-3406
    ISSN 0144-8420
    DOI 10.1093/oxfordjournals.rpd.a006421
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Laboratory Automation in Microbiology: Impact on Turnaround Time of Microbiological Samples in COVID Time.

    Fontana, Carla / Favaro, Marco / Pelliccioni, Marco / Minelli, Silvia / Bossa, Maria Cristina / Altieri, Anna / D'Orazi, Carlo / Paliotta, Federico / Cicchetti, Oriana / Minieri, Marilena / Prezioso, Carla / Limongi, Dolores / D'agostini, Cartesio

    Diagnostics (Basel, Switzerland)

    2023  Volume 13, Issue 13

    Abstract: Background: Laboratory Automation (LA) is an innovative technology that is currently available for microbiology laboratories. LA can be a game changer by revolutionizing laboratory workflows through efficiency improvement and is also effective in the ... ...

    Abstract Background: Laboratory Automation (LA) is an innovative technology that is currently available for microbiology laboratories. LA can be a game changer by revolutionizing laboratory workflows through efficiency improvement and is also effective in the organization and standardization of procedures, enabling staff requalification. It can provide an important return on investment (time spent redefining the workflow as well as direct costs of instrumentation) in the medium to long term.
    Methods: Here, we present our experience with the WASPLab
    Results: TAT recorded over time showed a significant decrease: from 97 h to 53.5 h (Δ43.5 h) for BCs and from 73 h to 58 h (Δ20 h) for BLs. Despite the introduction of the WASPLab
    Conclusions: LA can significantly enhance laboratory performance and, due to the significant reduction in reporting time, can have an effective impact on clinical choices and therefore on patient outcomes. Therefore, the initial costs of LA adoption must be considered worthwhile.
    Language English
    Publishing date 2023-07-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics13132243
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The ICRU Proposal for New Operational Quantities for External Radiation.

    Otto, T / Hertel, N E / Bartlett, D T / Behrens, R / Bordy, J-M / Dietze, G / Endo, A / Gualdrini, G / Pelliccioni, M

    Radiation protection dosimetry

    2017  Volume 180, Issue 1-4, Page(s) 10–16

    Abstract: Report Committee 26 of the ICRU proposes a set of operational quantities for radiation protection for external radiation, directly based on effective dose and for an extended range of particles and energies. It is accompanied by quantities for estimating ...

    Abstract Report Committee 26 of the ICRU proposes a set of operational quantities for radiation protection for external radiation, directly based on effective dose and for an extended range of particles and energies. It is accompanied by quantities for estimating deterministic effects to the eye lens and the local skin. The operational quantities are designed to overcome the conceptual and technical shortcomings of those presently in use. This paper describes the proposed operational quantities, and highlights the improvements with respect to the present, legal monitoring quantities.
    MeSH term(s) Calibration ; Humans ; International Agencies ; Lens, Crystalline/radiation effects ; Radiation Dosage ; Radiation Exposure/adverse effects ; Radiation Injuries/etiology ; Radiation Injuries/prevention & control ; Radiation Monitoring/standards ; Radiation Protection/standards
    Language English
    Publishing date 2017-11-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 225912-6
    ISSN 1742-3406 ; 0144-8420
    ISSN (online) 1742-3406
    ISSN 0144-8420
    DOI 10.1093/rpd/ncx243
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  8. Article: On the conversion coefficients for cosmic ray dosimetry.

    Ferrari, A / Pelliccioni, M

    Radiation protection dosimetry

    2003  Volume 104, Issue 3, Page(s) 211–220

    Abstract: Calculations of fluence-to-effective dose conversion coefficients have typically been limited to the standard irradiation geometries of the human body: anterior-to-posterior (AP), posterior-to-anterior (PA), lateral from the right side to the left side ( ... ...

    Abstract Calculations of fluence-to-effective dose conversion coefficients have typically been limited to the standard irradiation geometries of the human body: anterior-to-posterior (AP), posterior-to-anterior (PA), lateral from the right side to the left side (RLAT), lateral from the left side to the right side (LLAT), rotational around the vertical axis (ROT), and isotropic incidence from all directions (ISO). In order to estimate the doses to air crew members exposed to cosmic radiation, the geometrical conditions of irradiation are usually assumed to be isotropic. However, the assumption of isotropic irradiation is in many cases invalid for the high energy component of the radiation field, which is often peaked in the forward direction. Therefore, it was considered useful to extend the calculations of conversion coefficients to other geometries. New sets of conversion coefficients fluence-to-effective dose are presented for the semi-isotropic irradiation of the human body and for the irradiation from the top. Their application to cosmic ray dosimetry is discussed.
    MeSH term(s) Aircraft ; Background Radiation ; Body Burden ; Calibration ; Computer Simulation ; Cosmic Radiation ; Environmental Exposure/analysis ; Environmental Exposure/standards ; Humans ; Linear Energy Transfer ; Models, Biological ; Occupational Exposure/analysis ; Occupational Exposure/standards ; Quality Control ; Radiation Protection/methods ; Radiation Protection/standards ; Radiometry/instrumentation ; Radiometry/methods ; Radiometry/standards ; Relative Biological Effectiveness ; Reproducibility of Results ; Risk Assessment/methods ; Risk Assessment/standards ; Sensitivity and Specificity ; Solar Energy
    Language English
    Publishing date 2003-07-11
    Publishing country England
    Document type Comparative Study ; Evaluation Studies ; Journal Article ; Validation Studies
    ZDB-ID 225912-6
    ISSN 1742-3406 ; 0144-8420
    ISSN (online) 1742-3406
    ISSN 0144-8420
    DOI 10.1093/oxfordjournals.rpd.a006184
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Musculo-skeletal phenotype of Costello syndrome and cardio-facio-cutaneous syndrome: insights on the functional assessment status.

    Leoni, Chiara / Romeo, Domenico Marco / Pelliccioni, Michele / Di Già, Mariangela / Onesimo, Roberta / Giorgio, Valentina / Flex, Elisabetta / Tedesco, Marta / Tartaglia, Marco / Rigante, Donato / Valassina, Antonio / Zampino, Giuseppe

    Orphanet journal of rare diseases

    2021  Volume 16, Issue 1, Page(s) 43

    Abstract: Background: Costello syndrome (CS) and cardio-facio-cutaneous syndrome (CFCS) belong to the RASopathies, a group of neurodevelopmental disorders with skeletal anomalies. Due to their rarity, the characterization of the musculo-skeletal phenotype in both ...

    Abstract Background: Costello syndrome (CS) and cardio-facio-cutaneous syndrome (CFCS) belong to the RASopathies, a group of neurodevelopmental disorders with skeletal anomalies. Due to their rarity, the characterization of the musculo-skeletal phenotype in both disorders has been poorly characterized.
    Patients and methods: Herein we reported data on orthopedic findings and functional status of a large sample of CS and CFCS patients. Thirty-four patients (CS = 17 and CFCS = 17) were recruited. Functional and disability evaluations were performed by assessing the 6-min walking test (6MWT) and Pediatric Outcomes Data Collection Instrument (PODCI). Genotype/phenotype correlation was also provided.
    Results: Orthopedic manifestations are highly prevalent in CS and CFCS and overlap in the two disorders. Overall, patients with CS harboring the recurrent HRAS Gly12Ser substitution show a more severe skeletal phenotype compared to patients carrying the Gly12Ala and Gly13Cys variants. Among CFCS patients, those with the MAP2K1/2 variant show different skeletal characteristics compared to BRAF variants, with a higher prevalence of orthopedic abnormalities. Functional assessment showed that patients with CS and CFCS reached lower values compared to the general population, with CFCS patients displaying the lowest scores.
    Conclusions: Orthopedic manifestations appear universal features of CS and CFCS and they can evolve across patients' life. Longitudinal assessment of disability status by using 6MWT and PODCI could be useful to evaluate the functional impact of orthopedic manifestations on patients' outcome and help planning a tailored treatment of these comorbidities.
    MeSH term(s) Child ; Costello Syndrome/genetics ; Ectodermal Dysplasia ; Facies ; Failure to Thrive ; Heart Defects, Congenital/genetics ; Humans ; Phenotype
    Language English
    Publishing date 2021-01-22
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1750-1172
    ISSN (online) 1750-1172
    DOI 10.1186/s13023-021-01674-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: A mathematical model of aircraft for evaluating the effects of shielding structure on aircrew exposure.

    Ferrari, A / Pelliccioni, M / Villari, R

    Radiation protection dosimetry

    2006  Volume 116, Issue 1-4 Pt 2, Page(s) 331–335

    Abstract: To investigate the influence of the aircraft structures and contents on the exposure of aircrew to the galactic component of cosmic rays, a mathematical model of an aeroplane has been developed. The irradiation of the mathematical model in the cosmic ray ...

    Abstract To investigate the influence of the aircraft structures and contents on the exposure of aircrew to the galactic component of cosmic rays, a mathematical model of an aeroplane has been developed. The irradiation of the mathematical model in the cosmic ray environment has been simulated using the Monte Carlo transport code FLUKA. Effective dose andambient dose-equivalent rates have been determined inside the aircraft at several locations along the fuselage at a typicaI civil aviation altitude. A significant effect of the shielding of aircraft structures has been observed on the ambient dose-equivalent rates, while the impact on the effective dose rates seems to be minor. Care should be taken in positioning the detectors onboard when the measurements are aimed at validating the codes.
    MeSH term(s) Aerospace Medicine/instrumentation ; Aerospace Medicine/methods ; Aircraft/instrumentation ; Body Burden ; Computer Simulation ; Computer-Aided Design ; Cosmic Radiation ; Equipment Design ; Equipment Failure Analysis ; Humans ; Models, Statistical ; Monte Carlo Method ; Occupational Exposure/analysis ; Radiation Dosage ; Radiation Protection/methods ; Radiometry/instrumentation ; Radiometry/methods ; Relative Biological Effectiveness ; Risk Assessment/methods ; Risk Factors ; Software
    Language English
    Publishing date 2006-03-24
    Publishing country England
    Document type Evaluation Studies ; Journal Article
    ZDB-ID 225912-6
    ISSN 1742-3406 ; 0144-8420
    ISSN (online) 1742-3406
    ISSN 0144-8420
    DOI 10.1093/rpd/nci144
    Database MEDical Literature Analysis and Retrieval System OnLINE

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