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  1. Article: A musculoskeletal multifactorial individualised programme for hamstring muscle injury risk reduction in professional football: results of a prospective cohort study.

    Edouard, Pascal / Lahti, Johan / Fleres, Luca / Ahtiainen, Juha / Ulvila, Juha-Jaakko / Lehtinen, Tiitus / Virtanen, Niklas / Taipale, Toni / Bellver, Michel / Peltonen, Ville / Thibault, Max / Huuhka, Toni / Toivonen, Risto-Matti / Morin, Jean-Benoit / Mendiguchia, Jurdan

    BMJ open sport & exercise medicine

    2024  Volume 10, Issue 1, Page(s) e001866

    Abstract: Objective: To test whether a musculoskeletal multifactorial and individualised hamstring muscle injury (HMI) risk reduction programme could reduce HMI risk in professional football.: Methods: We conducted a prospective cohort study in Finnish premier ...

    Abstract Objective: To test whether a musculoskeletal multifactorial and individualised hamstring muscle injury (HMI) risk reduction programme could reduce HMI risk in professional football.
    Methods: We conducted a prospective cohort study in Finnish premier football league teams, with the 2019 season used as a control and an intervention conducted in the 2021 season. Screening was conducted to provide individualised programmes and monitor progress. Cox regression with hazard ratio (HR) was used with HMI as outcome and season as explanatory variable, including all players for primary analysis and those who performed the two seasons for secondary analysis.
    Results: 90 players were included in the control and 87 in the intervention seasons; 31 players performed in the 2 seasons. Twenty HMIs were recorded during the control and 16 during the intervention seasons. Cox regression analyses revealed that HMI risk at any given time was not significantly different between control and intervention seasons (for all players: HR 0.77 (95% CI 0.39 to 1.51), p=0.444; for the 31 players: HR 0.32 (95% CI 0.01 to 1.29), p=0.110)). For the 31 players, the HMI burden was significantly reduced in the intervention compared with the control season (RR 0.67 (95% CI 0.53 to 0.85)). Higher compliance with knee strength training, maximal velocity exposure and lower performance reductions in maximal theoretical horizontal force and knee flexor force were associated with lower HMI incidence.
    Conclusions: Although the primary analysis did not reveal any significant effect of the intervention to reduce HMI risk in professional football, the programme was feasible, and additional secondary analyses showed a significant association between the intervention and lower HMI burden, incidence and risk.
    Language English
    Publishing date 2024-02-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2817580-3
    ISSN 2055-7647
    ISSN 2055-7647
    DOI 10.1136/bmjsem-2023-001866
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Randomized controlled trial comparing pit crew resuscitation model against standard advanced life support training.

    Peltonen, Ville / Peltonen, Laura-Maria / Rantanen, Matias / Säämänen, Jari / Vänttinen, Olli / Koskela, Jaana / Perkonoja, Katariina / Salanterä, Sanna / Tommila, Miretta

    Journal of the American College of Emergency Physicians open

    2022  Volume 3, Issue 3, Page(s) e12721

    Abstract: Objectives: Pit crew models are designed to improve teamwork in critical medical situations, like advanced life support (ALS). We investigated if a pit crew model training improves performance assessment and ALS skills retention when compared to ... ...

    Abstract Objectives: Pit crew models are designed to improve teamwork in critical medical situations, like advanced life support (ALS). We investigated if a pit crew model training improves performance assessment and ALS skills retention when compared to standard ALS education.
    Methods: This was a prospective, blinded, randomized, and controlled, parallel-group trial. We recruited students to 4-person resuscitation teams. We video recorded simulated ALS-situations after the ALS education and after 6-month follow-up. We analyzed technical skills (TS) and non-technical skills (NTS) demonstrated in them with an instrument measuring TS and NTS, and used a linear mixed model to model the difference between the groups in the TS and NTS. Another linear model was used to explore the difference between the groups in hands-on ratio and hands-free time. The difference in the total assessment score was analyzed with the Mann-Whitney U-test. The primary outcome was the difference in the total assessment score between the groups at follow-up. ALS skills were considered to be a secondary outcome.
    Results: Twenty-six teams underwent randomization. Twenty-two teams received the allocated education. Fifteen teams were evaluated at 6-month follow-up: 7 in the intervention group and 8 in the control group. At 6-month follow-up, the median (Q
    Conclusion: We found no difference in overall performance between the study arms. However, trends indicate that the pit crew model may help to retain ALS skills in different areas like chest compression quality.
    Language English
    Publishing date 2022-05-16
    Publishing country United States
    Document type Journal Article
    ISSN 2688-1152
    ISSN (online) 2688-1152
    DOI 10.1002/emp2.12721
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: An observational study of technical and non-technical skills in advanced life support in the clinical setting.

    Peltonen, Ville / Peltonen, Laura-Maria / Salanterä, Sanna / Hoppu, Sanna / Elomaa, Jaana / Pappila, Tomi / Hevonoja, Eeva / Hurme, Saija / Perkonoja, Katariina / Elomaa, Teemu / Tommila, Miretta

    Resuscitation

    2020  Volume 153, Page(s) 162–168

    Abstract: Objective: Technical skills (TS) and non-technical skills (NTS) are the primary elements ensuring patient safety during advanced life support (ALS) and effective crisis resource management (CRM). Both skills are needed to perform high-quality ALS, ... ...

    Abstract Objective: Technical skills (TS) and non-technical skills (NTS) are the primary elements ensuring patient safety during advanced life support (ALS) and effective crisis resource management (CRM). Both skills are needed to perform high-quality ALS, though they are traditionally practiced separately. The evidence of the association between NTS and TS in high-quality ALS performance is insufficient. Hence, we aimed to evaluate the association between the skills in real-life in-hospital ALS situations.
    Methods: We video recorded real-life in-hospital ALS situations, analyzed TS and NTS demonstrated in them with an instrument measuring TS and NTS, and tested the linear association between NTS and TS using a linear mixed model.
    Results: Among 50 real-life in-hospital ALS situations that we recorded, 20 had adequate data for analysis. NTS and TS total scores were associated with one another (slope 0.48, P < 0.001). All NTS subcategories were associated with the TS total score (slopes ranging from 0.29 to 0.39, P < 0.001). The NTS total score and TS subcategories (chest compression quality, ventilation quality, rhythm control and defibrillation quality) were associated with one another (slopes ranging from 0.37 to 0.56, P < 0.01).
    Conclusions: The resuscitation teams who demonstrated good NTS also performed the technical aspects of ALS better. The results suggest that NTS and TS have an association with one another in real-life in-hospital ALS situations. NTS performance had the most evident association with chest compression quality and rhythm control and defibrillation quality; these are considered the most crucial elements affecting outcomes of ALS. The findings of the study present novel information of what and why to emphasize in ALS training.
    Clinical trial registration: ClinicalTrials.gov, NCT03017144.
    MeSH term(s) Clinical Competence ; Humans ; Patient Safety ; Resuscitation
    Language English
    Publishing date 2020-06-16
    Publishing country Ireland
    Document type Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 189901-6
    ISSN 1873-1570 ; 0300-9572
    ISSN (online) 1873-1570
    ISSN 0300-9572
    DOI 10.1016/j.resuscitation.2020.06.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Hemoglobin expression in rat experimental granulation tissue.

    Tommila, Miretta / Stark, Christoffer / Jokilammi, Anne / Peltonen, Ville / Penttinen, Risto / Ekholm, Erika

    Journal of molecular cell biology

    2011  Volume 3, Issue 3, Page(s) 190–196

    Abstract: The general opinion that hemoglobin is only a carrier protein for oxygen and carbon dioxide has been challenged by several recent studies showing hemoglobin expression in other cells than those of the erythroid series, for example, in macrophages. We ... ...

    Abstract The general opinion that hemoglobin is only a carrier protein for oxygen and carbon dioxide has been challenged by several recent studies showing hemoglobin expression in other cells than those of the erythroid series, for example, in macrophages. We discovered β-globin expression in rat experimental granulation tissue induced by subcutaneously implanted cellulose sponges. Closer investigation revealed also α-globin expression. The first peak of the biphasic globin expression noticed during granulation tissue formation correlated with the invasion of monocytes/macrophages, whereas the second one seemed to be connected to the appearance of hematopoietic progenitors. Data presented in this study indicate globin expression both in macrophages and in immature erythroid cells as validated by erythroid-specific markers.
    MeSH term(s) Animals ; Erythroid Cells/metabolism ; Erythropoiesis/genetics ; Gene Expression Profiling ; Gene Expression Regulation ; Granulation Tissue/metabolism ; Hemoglobins/genetics ; Hemoglobins/metabolism ; Macrophages/metabolism ; Male ; Nitric Oxide Synthase/genetics ; Nitric Oxide Synthase/metabolism ; RNA, Messenger/metabolism ; Rats ; Rats, Sprague-Dawley ; alpha-Globins/genetics ; alpha-Globins/metabolism ; beta-Globins/genetics ; beta-Globins/metabolism
    Chemical Substances Hemoglobins ; RNA, Messenger ; alpha-Globins ; beta-Globins ; Nitric Oxide Synthase (EC 1.14.13.39)
    Language English
    Publishing date 2011-06
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2500949-7
    ISSN 1759-4685 ; 1674-2788
    ISSN (online) 1759-4685
    ISSN 1674-2788
    DOI 10.1093/jmcb/mjq036
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book: Hämeenlinnan I Apteekin waiheita;

    Peltonen, Ville

    200 wuoden aialta

    1954  

    Institution Hämeenlinnan Apteeki (1st)
    MeSH term(s) Pharmacy/history
    Keywords Finland
    Language Finnish
    Size 7 p., ill., ports.
    Publishing place Hämeenlinna
    Document type Book
    Database Catalogue of the US National Library of Medicine (NLM)

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