LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 11

Search options

  1. Article ; Online: Complete chloroplast genome sequences of

    Xie, Jie-Nan / Wang, Da / Peng, Jing-Yi / Wang, Yi / Zhou, Qiang

    Mitochondrial DNA. Part B, Resources

    2022  Volume 7, Issue 7, Page(s) 1280–1281

    Abstract: In this study, we assembled and described the complete chloroplast genome (cp) ... ...

    Abstract In this study, we assembled and described the complete chloroplast genome (cp) of
    Language English
    Publishing date 2022-07-12
    Publishing country England
    Document type Journal Article
    ISSN 2380-2359
    ISSN (online) 2380-2359
    DOI 10.1080/23802359.2022.2097026
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Article ; Online: Early pheromone perception remodels neurodevelopment and accelerates neurodegeneration in adult C. elegans.

    Peng, Jing-Yi / Liu, Xuqing / Zeng, Xian-Ting / Hao, Yue / Zhang, Jia-Hui / Li, Qian / Tong, Xia-Jing

    Cell reports

    2023  Volume 42, Issue 6, Page(s) 112598

    Abstract: Age-associated neurodegenerative disorders such as Parkinson's and Alzheimer's diseases are mainly caused by protein aggregation. The etiologies of these neurodegenerative diseases share a chemical environment. However, how chemical cues modulate ... ...

    Abstract Age-associated neurodegenerative disorders such as Parkinson's and Alzheimer's diseases are mainly caused by protein aggregation. The etiologies of these neurodegenerative diseases share a chemical environment. However, how chemical cues modulate neurodegeneration remains unclear. Here, we found that in Caenorhabditis elegans, exposure to pheromones in the L1 stage accelerates neurodegeneration in adults. Perception of pheromones ascr#3 and ascr#10 is mediated by chemosensory neurons ASK and ASI. ascr#3 perceived by G protein-coupled receptor (GPCR) DAF-38 in ASK activates glutamatergic transmission into AIA interneurons. ascr#10 perceived by GPCR STR-2 in ASI activates the secretion of neuropeptide NLP-1, which binds to the NPR-11 receptor in AIA. Activation of both ASI and ASK is required and sufficient to remodel neurodevelopment via AIA, which triggers insulin-like signaling and inhibits autophagy in adult neurons non-cell-autonomously. Our work reveals how pheromone perception at the early developmental stage modulates neurodegeneration in adults and provides insights into how the external environment impacts neurodegenerative diseases.
    MeSH term(s) Animals ; Caenorhabditis elegans/metabolism ; Signal Transduction ; Pheromones/metabolism ; Caenorhabditis elegans Proteins/metabolism ; Insulin/metabolism ; Perception
    Chemical Substances Pheromones ; Caenorhabditis elegans Proteins ; Insulin
    Language English
    Publishing date 2023-06-07
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2649101-1
    ISSN 2211-1247 ; 2211-1247
    ISSN (online) 2211-1247
    ISSN 2211-1247
    DOI 10.1016/j.celrep.2023.112598
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article: 

    Peng, Jing-Yi / Zhang, Dai-Gui / Deng, Tao / Huang, Xian-Han / Chen, Jun-Tong / Meng, Ying / Wang, Yi / Zhou, Qiang

    PhytoKeys

    2022  Volume 210, Page(s) 1–13

    Abstract: ... A new ... ...

    Abstract A new species
    Language English
    Publishing date 2022-09-27
    Publishing country Bulgaria
    Document type Journal Article
    ZDB-ID 2579891-1
    ISSN 1314-2003 ; 1314-2011
    ISSN (online) 1314-2003
    ISSN 1314-2011
    DOI 10.3897/phytokeys.210.89480
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Newly reported chloroplast genome of Sinosenecio albonervius Y. Liu & Q. E. Yang and comparative analyses with other Sinosenecio species.

    Peng, Jing-Yi / Zhang, Xiao-Shuang / Zhang, Dai-Gui / Wang, Yi / Deng, Tao / Huang, Xian-Han / Kuang, Tian-Hui / Zhou, Qiang

    BMC genomics

    2022  Volume 23, Issue 1, Page(s) 639

    Abstract: Background: Sinosenecio B. Nordenstam (Asteraceae) currently comprises 44 species. To investigate the interspecific relationship, several chloroplast markers, including ndhC-trnV, rpl32-trnL, matK, and rbcL, are used to analyze the phylogeny of ... ...

    Abstract Background: Sinosenecio B. Nordenstam (Asteraceae) currently comprises 44 species. To investigate the interspecific relationship, several chloroplast markers, including ndhC-trnV, rpl32-trnL, matK, and rbcL, are used to analyze the phylogeny of Sinosenecio. However, the chloroplast genomes of this genus have not been thoroughly investigated. We sequenced and assembled the Sinosenecio albonervius chloroplast genome for the first time. A detailed comparative analysis was performed in this study using the previously reported chloroplast genomes of three Sinosenecio species.
    Results: The results showed that the chloroplast genomes of four Sinosenecio species exhibit a typical quadripartite structure. There are equal numbers of total genes, protein-coding genes and RNA genes among the annotated genomes. Per genome, 49-56 simple sequence repeats and 99 repeat sequences were identified. Thirty codons were identified as RSCU values greater than 1 in the chloroplast genome of S. albonervius based on 54 protein-coding genes, indicating that they showed biased usage. Among 18 protein-coding genes, 46 potential RNA editing sites were discovered. By comparing these chloroplast genomes' structures, inverted repeat regions and coding regions were more conserved than single-copy and non-coding regions. The junctions among inverted repeat and single-copy regions showed slight difference. Several hot spots of genomic divergence were detected, which can be used as new DNA barcodes for species identification. Phylogenetic analysis of the whole chloroplast genome showed that the four Sinosenecio species have close interspecific relationships.
    Conclusions: The complete chloroplast genome of Sinosenecio albonervius was revealed in this study, which included a comparison of Sinosenecio chloroplast genome structure, variation, and phylogenetic analysis for related species. These will help future research on Sinosenecio taxonomy, identification, origin, and evolution to some extent.
    MeSH term(s) Asteraceae/genetics ; Chloroplasts/genetics ; Genome, Chloroplast ; Microsatellite Repeats/genetics ; Phylogeny
    Language English
    Publishing date 2022-09-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041499-7
    ISSN 1471-2164 ; 1471-2164
    ISSN (online) 1471-2164
    ISSN 1471-2164
    DOI 10.1186/s12864-022-08872-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Sinosenecio yangii (Asteraceae), a new species from Guizhou, China

    Peng, Jing-Yi / Zhang, Dai-Gui / Deng, Tao / Huang, Xian-Han / Chen, Jun-Tong / Meng, Ying / Wang, Yi / Zhou, Qiang

    PhytoKeys. 2022 Sept. 27, v. 210 p.1-13

    2022  

    Abstract: AbstractA new species Sinosenecio yangii D.G. Zhang & Q. Zhou (Asteraceae, Senecioneae) from Guizhou Province, China, is described and illustrated based on its morphological characteristics and molecular evidence. It closely resembles S. confervifer and ...

    Abstract AbstractA new species Sinosenecio yangii D.G. Zhang & Q. Zhou (Asteraceae, Senecioneae) from Guizhou Province, China, is described and illustrated based on its morphological characteristics and molecular evidence. It closely resembles S. confervifer and S. guangxiensis, the former in the scapigerous habit and smooth and glabrous achene surface, the latter in the calyculate involucre and purple abaxial leaf surface, and both in the shape and indumentum of leaf lamina, but differs markedly from the latter two in having fewer capitula and epappose achenes. Phylogenetic analysis based on nrITS and ndhC-trnV sequences shows that this new species belongs to the S. latouchei clade and is sister to S. guangxiensis with moderate support.
    Keywords Asteraceae ; achenes ; leaves ; new species ; phylogeny ; China ; molecular evidence ; morphology ; pappus
    Language English
    Dates of publication 2022-0927
    Size p. 1-13.
    Publishing place Pensoft Publishers
    Document type Article ; Online
    ZDB-ID 2579891-1
    ISSN 1314-2003 ; 1314-2011
    ISSN (online) 1314-2003
    ISSN 1314-2011
    DOI 10.3897/phytokeys.210.89480
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article: Saxifraga viridiflora (Saxifragaceae), an unusual new species from Guangxi, China

    Zhang, Xin-Jian / Fu*, Quan-Sheng / Chen, Jun-Tong / Li, Li-Juan / Luo, Peng-Rui / Peng, Jing-Yi / Huang, Xian-Han / Sun, Hang / Deng, Tao

    PhytoKeys. 2021 Oct. 25, v. 184

    2021  

    Abstract: Saxifraga viridiflora, a remarkable new species of the genus Saxifragasect.Irregulares (Saxifragaceae) from Guangxi, is described and illustrated herein. This new species morphologically differs from all known S.sect.Irregulares taxa by its greenish ... ...

    Abstract Saxifraga viridiflora, a remarkable new species of the genus Saxifragasect.Irregulares (Saxifragaceae) from Guangxi, is described and illustrated herein. This new species morphologically differs from all known S.sect.Irregulares taxa by its greenish petals, verruculose sepals, and thick leathery leaf blade abaxially scarlet with white spots.
    Keywords Saxifraga ; leaf blade ; new species ; China
    Language English
    Dates of publication 2021-1025
    Size p. 19-26.
    Publishing place Pensoft Publishers
    Document type Article
    ZDB-ID 2579891-1
    ISSN 1314-2003 ; 1314-2011
    ISSN (online) 1314-2003
    ISSN 1314-2011
    DOI 10.3897/phytokeys.184.73421
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Piperlongumine conquers temozolomide chemoradiotherapy resistance to achieve immune cure in refractory glioblastoma via boosting oxidative stress-inflamation-CD8

    Liu, Feng / Zhou, Qian / Jiang, Hai-Feng / Zhang, Ting-Ting / Miao, Cheng / Xu, Xiao-Hong / Wu, Jia-Xing / Yin, Song-Lin / Xu, Shi-Jie / Peng, Jing-Yi / Gao, Pan-Pan / Cao, Xuan / Pan, Feng / He, Ximiao / Chen, Xiao Qian

    Journal of experimental & clinical cancer research : CR

    2023  Volume 42, Issue 1, Page(s) 118

    Abstract: Background: The failure of novel therapies effective in preclinical animal models largely reflects the fact that current models do not really mimic the pathological/therapeutic features of glioblastoma (GBM), in which the most effective temozolomide ... ...

    Abstract Background: The failure of novel therapies effective in preclinical animal models largely reflects the fact that current models do not really mimic the pathological/therapeutic features of glioblastoma (GBM), in which the most effective temozolomide chemoradiotherapy (RT/TMZ) regimen can only slightly extend survival. How to improve RT/TMZ efficacy remains a major challenge in clinic.
    Methods: Syngeneic G422
    Results: Here we identified that glutathione metabolism was most significantly altered in metabolomics analysis upon RT/TMZ therapies in a truly refractory and reliable mouse triple-negative GBM (G422
    Conclusion: Our findings demonstrate that PL reverses RT/TMZ-reduced ROS and synergistically resets tumor microenvironment to cure GBM. RT/TMZ/PL or RT/TMZ/PL/αPD1 exacts effective immune cure in refractory GBM, deserving a priority for clinical trials.
    MeSH term(s) Humans ; Animals ; Mice ; Glioblastoma/drug therapy ; Temozolomide/pharmacology ; Temozolomide/therapeutic use ; Reactive Oxygen Species ; CD8-Positive T-Lymphocytes ; Oxidative Stress ; Glioma ; Chemoradiotherapy ; Tumor Microenvironment
    Chemical Substances Temozolomide (YF1K15M17Y) ; piperlongumine (SGD66V4SVJ) ; Reactive Oxygen Species
    Language English
    Publishing date 2023-05-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 803138-1
    ISSN 1756-9966 ; 0392-9078
    ISSN (online) 1756-9966
    ISSN 0392-9078
    DOI 10.1186/s13046-023-02686-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2065: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article: Defects and asymmetries in the visual pathway of non-human primates with natural strabismus and amblyopia.

    Liu, Feng / Wang, Zhong-Hao / Huang, Wanjing / Xu, Ying / Sang, Xuan / Liu, Rui-Feng / Li, Zhou-Yue / Bi, Ya-Lan / Tang, Lei / Peng, Jing-Yi / Wei, Jia-Ru / Miao, Zhi-Chao / Yan, Jian-Hua / Liu, Sheng

    Zoological research

    2022  Volume 44, Issue 1, Page(s) 153–168

    Abstract: Strabismus and amblyopia are common ophthalmologic developmental diseases caused by abnormal visual experiences. However, the underlying pathogenesis and visual defects are still not fully understood. Most studies have used experimental interference to ... ...

    Abstract Strabismus and amblyopia are common ophthalmologic developmental diseases caused by abnormal visual experiences. However, the underlying pathogenesis and visual defects are still not fully understood. Most studies have used experimental interference to establish disease-associated animal models, while ignoring the natural pathophysiological mechanisms. This study was designed to investigate whether natural strabismus and amblyopia are associated with abnormal neurological defects. We screened one natural strabismic monkey (
    MeSH term(s) Animals ; Humans ; Visual Pathways ; Evoked Potentials, Visual ; Retrospective Studies ; Haplorhini
    Language English
    Publishing date 2022-12-08
    Publishing country China
    Document type Journal Article
    ISSN 2095-8137
    ISSN 2095-8137
    DOI 10.24272/j.issn.2095-8137.2022.254
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Article: Saxifragaviridiflora

    Zhang, Xin-Jian / Fu, Quan-Sheng / Chen, Jun-Tong / Li, Li-Juan / Luo, Peng-Rui / Peng, Jing-Yi / Huang, Xian-Han / Sun, Hang / Deng, Tao

    PhytoKeys

    2021  Volume 184, Page(s) 19–26

    Abstract: ... ...

    Abstract Saxifragaviridiflora
    Language English
    Publishing date 2021-10-25
    Publishing country Bulgaria
    Document type Journal Article
    ZDB-ID 2579891-1
    ISSN 1314-2003 ; 1314-2011
    ISSN (online) 1314-2003
    ISSN 1314-2011
    DOI 10.3897/phytokeys.184.73421
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Characterization of carbapenem-resistant hypervirulent Acinetobacter baumannii strains isolated from hospitalized patients in the mid-south region of China.

    Li, Jun / Yu, Ting / Luo, Yi / Peng, Jing-Yi / Li, Yu-Jia / Tao, Xiao-Yan / Hu, Yong-Mei / Wang, Hai-Chen / Zou, Ming-Xiang

    BMC microbiology

    2020  Volume 20, Issue 1, Page(s) 281

    Abstract: Background: Acinetobacter baumannii has traditionally been considered an opportunistic pathogen with low virulence. In this study, we characterized the carbapenem-resistant hypervirulent A. baumannii (CR-hvAB) stains isolated from our hospital in mid- ... ...

    Abstract Background: Acinetobacter baumannii has traditionally been considered an opportunistic pathogen with low virulence. In this study, we characterized the carbapenem-resistant hypervirulent A. baumannii (CR-hvAB) stains isolated from our hospital in mid-south region of China.
    Results: Blood samples collected between January 2017 and May 2019 were used for virulence experiments and biofilm assays of individual carbapenem-resistant A. baumannii (CR-AB) strains, performed using a Galleria mellonella infection model and crystal violet staining method, respectively. CR-AB isolates that induced high mortality in the G. mellonella infection model were subjected to genotyping, susceptibility testing, and clinical data analysis, and the genetic characterization of these isolates was performed by whole-genome sequencing (WGS). Among the 109 CR-AB clinical strains, the survival rate of G. mellonella larvae infected with 7 (6.4%) CR-AB isolates (number of strains with mortality of 0, 10 and 20% was 4, 1, and 2, respectively), was significantly lower than that of A. baumannii ATCC 19606 (100.0%) and the remaining CR-AB isolates (> 80.0%). Consistent with these results, patients infected with these seven isolates had an average 7-day mortality rate of 42.9%, suggesting that the isolates were CR-hvAB. These seven isolates belonged to four sequence types (STs): ST457, ST195, ST369, and ST2088 (a new ST), and mainly ST457 (n = 4). The results of the biofilm study showed that eight strains had powerful biofilm ability (strong [n = 1] and moderate [n = 7] biofilm producers) including these seven CR-hvAB isolates.
    Conclusions: CR-hvAB isolates that induced a high mortality rate were cloned in our hospital, most of which belonged to ST457; thus, monitoring of these strains, particularly ST457, should be strengthened in the future. Meanwhile, A. baumannii, which was isolated from blood specimens and found to powerful biofilm-forming ability, is a probable hvAB isolate.
    MeSH term(s) Acinetobacter Infections/drug therapy ; Acinetobacter Infections/etiology ; Acinetobacter Infections/microbiology ; Acinetobacter baumannii/drug effects ; Acinetobacter baumannii/genetics ; Acinetobacter baumannii/isolation & purification ; Acinetobacter baumannii/pathogenicity ; Adolescent ; Adult ; Aged ; Animals ; Anti-Bacterial Agents/pharmacology ; Biofilms ; Carbapenems/pharmacology ; Child ; China ; Disease Models, Animal ; Drug Resistance, Bacterial/genetics ; Humans ; Microbial Sensitivity Tests ; Middle Aged ; Moths/microbiology ; Phylogeny ; Virulence/genetics ; Young Adult
    Chemical Substances Anti-Bacterial Agents ; Carbapenems
    Language English
    Publishing date 2020-09-14
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1471-2180
    ISSN (online) 1471-2180
    DOI 10.1186/s12866-020-01957-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top