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  1. Article ; Online: Research on Green and Low-Carbon Development Path of the Electric Power Industry

    Yaohua WANG / Peng XIA / Jun LIU

    Chinese Journal of Urban and Environmental Studies, Vol 11, Iss

    2023  Volume 02

    Abstract: In the analogy where achieving the “carbon peaking and carbon neutrality” goals (the “dual carbon” goals) is compared to a battle, energy is the main battlefield, and electric power the main force. The low-carbon transformation path of the electric power ...

    Abstract In the analogy where achieving the “carbon peaking and carbon neutrality” goals (the “dual carbon” goals) is compared to a battle, energy is the main battlefield, and electric power the main force. The low-carbon transformation path of the electric power industry exerts fundamental impact on progress towards carbon peaking and carbon neutrality of the whole society. Therefore, this paper first analyzes challenges and opportunities faced by the electric power industry to achieve the “dual carbon” goals; secondly, on the basis of deep low-carbon, zero-carbon and negative-carbon scenarios of the electric power industry, this paper quantifies and delves into the consumption structure of primary energy and final energy, as well as the future development positioning and trend of different categories of energy. Based on the research results, this paper proposes low-carbon transformation path of the electric power system at the stages of carbon peaking, deep low-carbon and carbon neutrality, and analyzes the trend of power supply cost changes in different scenarios. On this basis, a series of implementation key points and measures are proposed to adapt to green and low-carbon transformation of the electric power industry, covering areas such as coal-fired electric power development positioning, new energy development and utilization, diversified supply and demand, new energy industry chain, and power supply costs, and so forth.
    Keywords Carbon peaking ; carbon neutrality ; electric power ; green and low-carbon ; Urbanization. City and country ; HT361-384 ; Environmental sciences ; GE1-350
    Subject code 690
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher World Scientific Publishing Co. Pte Ltd.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Research on the stability evaluation method of anchored slopes based on group decision making and matter element analysis

    Peng Xia / Chunye Ying

    Scientific Reports, Vol 11, Iss 1, Pp 1-

    2021  Volume 12

    Abstract: Abstract This research is focused on the evaluation method of anchored slope stability, and an accurate evaluation method with a simple operation is proposed. Group decision theory and the analytic hierarchy process are used to determine the weight of ... ...

    Abstract Abstract This research is focused on the evaluation method of anchored slope stability, and an accurate evaluation method with a simple operation is proposed. Group decision theory and the analytic hierarchy process are used to determine the weight of each evaluation element, the correlation degree of each indicator is determined based on matter element analysis theory, and inverse hierarchical calculations are performed based on the obtained weight value and correlation degree to finally obtain the criteria layer correlation degree used for stability evaluation. The results show the following: (1) the evaluation method better integrates the effects of multiple factors on the stability of the anchored slope, and the evaluation results are accurate and consistent with the actual situation of the project; (2) the evaluation method can make full use of the experience of the expert group and effectively avoid the evaluation error caused by the subjective deviation of a single expert; (3) the group decision theory-entropy model was introduced to realize the quantitative evaluation of the reliability of expert scoring and effectively improve the efficiency of expert discussion; and (4) the evaluation result is intuitive, and the correlation degree obtained can not only reflect the stability grade of the anchored slope but also reflect the "distance" between the anchored slope and other stability grades.
    Keywords Medicine ; R ; Science ; Q
    Subject code 650
    Language English
    Publishing date 2021-08-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: A six lipid metabolism related gene signature for predicting the prognosis of hepatocellular carcinoma

    Kequan Xu / Peng Xia / Pan Liu / Xiao Zhang

    Scientific Reports, Vol 12, Iss 1, Pp 1-

    2022  Volume 12

    Abstract: Abstract Globally, hepatocellular carcinoma (HCC) is one of the most lethal malignant tumors. Studies have shown that alterations in the tumor immune microenvironment (TIME) play a significant role in the pathogenesis and progression of HCC, and notably, ...

    Abstract Abstract Globally, hepatocellular carcinoma (HCC) is one of the most lethal malignant tumors. Studies have shown that alterations in the tumor immune microenvironment (TIME) play a significant role in the pathogenesis and progression of HCC, and notably, lipid metabolism has been shown to regulate TIME. Therefore, in predicting the prognosis and efficacy of immunotherapy in patients with HCC, lipid metabolism-related prognostic factors are highly relevant. mRNA expression data of HCC were obtained from the Cancer Genome Atlas (TCGA), International Cancer Genome Consortium (ICGC), and gene expression omnibus (GEO) databases. and lipid metabolism-related genes were also obtained from the GSEA databases. Least absolute shrinkage and selection operator regression analysis, univariate and multivariate Cox proportional hazards analysis were used to explore lipid metabolism-related prognostic genes and further construct a prognostic signature in the training set, ICGC and GSE54236 were used to validate the accuracy of the signature. qRT-PCR was used to detect the mRNA levels of lipid metabolism-related prognostic genes in HCC tissues and their paired adjacent tissues. Nile red staining was used to demonstrate lipid content in HCC tissues. Immunofluores-cence and ELISA were used to detect immune cells and immune responses in HCC tissues and serum. Six lipid metabolism-related genes (ADH1C, APEX1, ME1, S100A10, ACACA and CYP2C9) were identified as independent prognostic factors, which were used for risk model construction for HCC patients. The areas under the 1-, 2-, and 3-year ROC curves for the TCGA cohort were 0.758, 0.701 and 0.671, respectively. Compared with paired paracancerous tissues, qRT-PCR revealed that APEX1, ME1, S100A10 and ACACA were up-regulated in HCC tissues, whereas ADH1C and CYP2C9 were down-regulated in HCC tissues. Nile red staining indicated that this study showed that both the HCC tissue and serum of patients in the high-risk group exhibited lipid accumulation. Our identified prognostic model ...
    Keywords Medicine ; R ; Science ; Q
    Subject code 616
    Language English
    Publishing date 2022-12-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Design and Evaluation of a Polymer Support Fluid in a Soil–Rock Mixture

    Chunye Ying / Xinli Hu / Peng Xia / Haiyan Zhang

    Polymers, Vol 14, Iss 1402, p

    2022  Volume 1402

    Abstract: Soil–rock mixtures are commonly encountered in the construction of bored piles. Conventional bentonite support fluids have disadvantages, such as more significant environmental impacts, more complex mixing, bigger site footprint, weaker foundation ... ...

    Abstract Soil–rock mixtures are commonly encountered in the construction of bored piles. Conventional bentonite support fluids have disadvantages, such as more significant environmental impacts, more complex mixing, bigger site footprint, weaker foundation performance, and overall low economies. The present study conducted a comprehensive investigation of partially hydrolyzed polyacrylamide (PHPA) polymer fluids, an alternative to bentonite ones, to drill into a soil-limestone mixture. The fluid flow pattern, aging behavior, and the influence of finer silty clay on polymer fluid were explored. The test results showed that polymer fluids were reasonably well fitted to the power-law model and were a good alternative to the conventional bentonite ones. In terms of their aging behavior, the remaining active viscosity of the polymer was at least 70% after a prolonged aging time of up to 30 days, showing the effective on-site use of polymer fluids. The mixing of silty clay significantly reduced the apparent viscosity of polymer fluids, with 10% silty clay causing a viscosity reduction of 76%, indicating the importance of fluid control in drilling these materials. A polymer formula, water + 0.08%PHPA + 0.1~0.5%Na 2 CO 3 , was proposed and was verified by drilling into a soil–limestone mixture. The polymer fluids led to small radial displacements around the boreholes with a high drilling quality. This work would be helpful for consultants and contractors designing and constructing bored piles in soil and rock mixtures utilizing polymer fluids.
    Keywords polymer ; soil–rock mixture ; bored piles ; viscosity ; Organic chemistry ; QD241-441
    Language English
    Publishing date 2022-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Hardness-Dependent Water Quality Criteria for Protection of Freshwater Aquatic Organisms for Silver in China

    Qi Jin / Chenglian Feng / Peng Xia / Yingchen Bai

    International Journal of Environmental Research and Public Health, Vol 19, Iss 6067, p

    2022  Volume 6067

    Abstract: Silver is toxic to freshwater aquatic organisms and aquatic ecosystems, and it is necessary to develop regional water quality criteria (WQC) for silver to protect the freshwater aquatic organisms in China. The toxicity database of silver for freshwater ... ...

    Abstract Silver is toxic to freshwater aquatic organisms and aquatic ecosystems, and it is necessary to develop regional water quality criteria (WQC) for silver to protect the freshwater aquatic organisms in China. The toxicity database of silver for freshwater aquatic organisms involved 121 acute toxicity values for 35 species (6 phyla and 27 families) and 15 chronic toxicity values for 4 species (2 phyla and 4 families). Teleost fish showed the most sensitivity to silver after both short-term and long-term exposure. Significant correlations between the natural logarithms of hardness and the natural logarithms of acute silver toxicity were found for Daphnia magna , Oncorhynchus mykiss , and Pimephales promelas . The criterion maximum concentration (CMC) was calculated by the species sensitivity distribution method with sigmoid as the best fitting model (Adj R 2 0.9797), and the criterion continuous concentration (CCC) was obtained by the acute-to-chronic ratio method. The CMC and CCC of silver were <math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msup><mi mathvariant="normal">e</mi><mrow><mn>1.58</mn><mi>ln</mi><mrow><mo>(</mo><mrow><msub><mi>H</mi><mrow><msub><mrow><mi>CaCO</mi></mrow><mn>3</mn></msub></mrow></msub></mrow><mo>)</mo></mrow><mo>−</mo><mn>8.68</mn></mrow></msup></mrow></semantics></math> , and <math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msup><mi ...<br />
    Keywords silver ; water hardness ; water quality criteria ; species sensitivity distribution ; Medicine ; R
    Subject code 333
    Language English
    Publishing date 2022-05-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Advances in the application of low-intensity pulsed ultrasound to mesenchymal stem cells

    Peng Xia / Yi Shi / Xiaoju Wang / Xueping Li

    Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-

    2022  Volume 14

    Abstract: Abstract Mesenchymal stem cells (MSCs) are stem cells that exhibit self-renewal capacity and multi-directional differentiation potential. They can be extracted from the bone marrow and umbilical cord, as well as adipose, amnion, and other tissues. They ... ...

    Abstract Abstract Mesenchymal stem cells (MSCs) are stem cells that exhibit self-renewal capacity and multi-directional differentiation potential. They can be extracted from the bone marrow and umbilical cord, as well as adipose, amnion, and other tissues. They are widely used in tissue engineering and are currently considered an important source of cells in the field of regenerative medicine. Since certain limitations, such as an insufficient cell source, mature differentiation, and low transplantation efficiency, are still associated with MSCs, researchers have currently focused on improving the efficacy of MSCs. Low-intensity pulsed ultrasound (LIPUS) has mechanical, cavitation, and thermal effects that can produce different biological effects on organs, tissues, and cells. It can be used for fracture treatment, cartilage repair, and stem cell applications. An in-depth study of the role and mechanism of action of LIPUS in MSC treatment would promote our understanding of LIPUS and promote research in this field. In this article, we have reviewed the progress in research on the use of LIPUS with various MSCs and comprehensively discussed the progress in the use of LIPUS for promoting the proliferation, differentiation, and migration of MSCs, as well as its future prospects.
    Keywords Mesenchymal stem cells ; Low-intensity pulsed ultrasound ; Microbubble ; Cell transplantation ; Medicine (General) ; R5-920 ; Biochemistry ; QD415-436
    Subject code 571
    Language English
    Publishing date 2022-05-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Mobility census for monitoring rapid urban development.

    Xiu, Gezhi / Wang, Jianying / Gross, Thilo / Kwan, Mei-Po / Peng, Xia / Liu, Yu

    Journal of the Royal Society, Interface

    2024  Volume 21, Issue 214, Page(s) 20230495

    Abstract: Monitoring urban structure and development requires high-quality data at high spatio-temporal resolution. While traditional censuses have provided foundational insights into demographic and socio-economic aspects of urban life, their pace may not always ... ...

    Abstract Monitoring urban structure and development requires high-quality data at high spatio-temporal resolution. While traditional censuses have provided foundational insights into demographic and socio-economic aspects of urban life, their pace may not always align with the pace of urban development. To complement these traditional methods, we explore the potential of analysing alternative big-data sources, such as human mobility data. However, these often noisy and unstructured big data pose new challenges. Here, we propose a method to extract meaningful explanatory variables and classifications from such data. Using movement data from Beijing, which are produced as a by-product of mobile communication, we show that meaningful features can be extracted, revealing, for example, the emergence and absorption of subcentres. This method allows the analysis of urban dynamics at a high-spatial resolution (here 500 m) and near real-time frequency, and high computational efficiency, which is especially suitable for tracing event-driven mobility changes and their impact on urban structures.
    MeSH term(s) Humans ; Censuses ; Beijing ; Urban Renewal ; Urban Population ; Population Dynamics
    Language English
    Publishing date 2024-05-08
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2156283-0
    ISSN 1742-5662 ; 1742-5689
    ISSN (online) 1742-5662
    ISSN 1742-5689
    DOI 10.1098/rsif.2023.0495
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Magnetic Microrobot Swarms with Polymeric Hands Catching Bacteria and Microplastics in Water.

    Ussia, Martina / Urso, Mario / Oral, Cagatay M / Peng, Xia / Pumera, Martin

    ACS nano

    2024  

    Abstract: The forefront of micro- and nanorobot research involves the development of smart swimming micromachines emulating the complexity of natural systems, such as the swarming and collective behaviors typically observed in animals and microorganisms, for ... ...

    Abstract The forefront of micro- and nanorobot research involves the development of smart swimming micromachines emulating the complexity of natural systems, such as the swarming and collective behaviors typically observed in animals and microorganisms, for efficient task execution. This study introduces magnetically controlled microrobots that possess polymeric sequestrant "hands" decorating a magnetic core. Under the influence of external magnetic fields, the functionalized magnetic beads dynamically self-assemble from individual microparticles into well-defined rotating planes of diverse dimensions, allowing modulation of their propulsion speed, and exhibiting a collective motion. These mobile microrobotic swarms can actively capture free-swimming bacteria and dispersed microplastics "on-the-fly", thereby cleaning aquatic environments. Unlike conventional methods, these microrobots can be collected from the complex media and can release the captured contaminants in a second vessel in a controllable manner, that is, using ultrasound, offering a sustainable solution for repeated use in decontamination processes. Additionally, the residual water is subjected to UV irradiation to eliminate any remaining bacteria, providing a comprehensive cleaning solution. In summary, this study shows a swarming microrobot design for water decontamination processes.
    Language English
    Publishing date 2024-05-08
    Publishing country United States
    Document type Journal Article
    ISSN 1936-086X
    ISSN (online) 1936-086X
    DOI 10.1021/acsnano.4c02115
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Prenatal dexamethasone exposure impairs rat blood-testis barrier function and sperm quality in adult offspring via GR/KDM1B/FSTL3/TGFβ signaling.

    Liu, Yi / Chen, Si-Jia / Ai, Can / Yu, Peng-Xia / Fang, Man / Wang, Hui

    Acta pharmacologica Sinica

    2024  

    Abstract: Both epidemiological and animal studies suggest that adverse environment during pregnancy can change the offspring development programming, but it is difficult to achieve prenatal early warning. In this study we investigated the impact of prenatal ... ...

    Abstract Both epidemiological and animal studies suggest that adverse environment during pregnancy can change the offspring development programming, but it is difficult to achieve prenatal early warning. In this study we investigated the impact of prenatal dexamethasone exposure (PDE) on sperm quality and function of blood-testis barrier (BTB) in adult offspring and the underlying mechanisms. Pregnant rats were injected with dexamethasone (0.1, 0.2 and 0.4 mg·kg
    Language English
    Publishing date 2024-03-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1360774-1
    ISSN 1745-7254 ; 0253-9756 ; 1671-4083
    ISSN (online) 1745-7254
    ISSN 0253-9756 ; 1671-4083
    DOI 10.1038/s41401-024-01244-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Endosomal Sorting Complex Required for Transport: The Molecular Machine for Ensuring Proper Mitosis.

    Gao, Wu-Luyi / Yang, Yu / Zhang, Peng-Xia / Shang, Yu

    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae

    2023  

    Abstract: Mitosis is a key step of eukaryote proliferation.Endosomal sorting complex required for transport, a protein complex closely associated with membrane shearing, is involved in endosome maturation, virus budding, and autophagy.The structural and functional ...

    Abstract Mitosis is a key step of eukaryote proliferation.Endosomal sorting complex required for transport, a protein complex closely associated with membrane shearing, is involved in endosome maturation, virus budding, and autophagy.The structural and functional abnormalities of the complex are associated with the occurrence and progression of cancer and other diseases.In this paper, we summarized the roles of the endosomal sorting complex required for transport in different stages of mitosis and reviewed the studies about the role of the complex in regulating mitosis in diseases.
    Language English
    Publishing date 2023-08-03
    Publishing country China
    Document type Journal Article
    ZDB-ID 604853-5
    ISSN 1000-503X
    ISSN 1000-503X
    DOI 10.3881/j.issn.1000-503X.15609
    Database MEDical Literature Analysis and Retrieval System OnLINE

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