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Article: Histiocytic sarcoma of the spleen without thrombocytopenia.

Peng, Ying-Jie / He, Ya-Qiong

Revista espanola de enfermedades digestivas

2024

Abstract: One case of histiocytic sarcoma of the spleen is reported. The patient, a 54-year-old female, presented with a huge soft tissue mass with a clear border and pseudo capsule in the splenic parenchyma on CT. The density of the mass was uneven, multifocal ... ...

Abstract	One case of histiocytic sarcoma of the spleen is reported. The patient, a 54-year-old female, presented with a huge soft tissue mass with a clear border and pseudo capsule in the splenic parenchyma on CT. The density of the mass was uneven, multifocal cystic necrosis and irregular bleeding were observed inside, but no calcification could be seen. On contrast-enhancement scan, the solid component of tumor exhibited moderate progressive enhancement, and area of cystic necrosis exhibited no enhancement. In MRI, T1WI showed mixed low signal, and T2WI showed mixed slightly high signal. The pathological diagnosis was histiocytic sarcoma.
Language	English
Publishing date	2024-01-29
Publishing country	Spain
Document type	Journal Article
ZDB-ID	1070381-0
ISSN	1130-0108 ; 0212-7512
ISSN	1130-0108 ; 0212-7512
DOI	10.17235/reed.2024.10249/2024
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Zs.B 199: Show issues

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Article ; Online: Enhanced treatment of acute organophosphorus pesticide poisoning using activated charcoal-embedded sodium alginate-polyvinyl alcohol hydrogel.

Yan, Li / Peng, Ying

Bio-medical materials and engineering

2024

Abstract: Background: The adsorption of activated charcoal is currently a major clinical treatment for acute organophosphorus pesticide poisoning (AOPP). However, the adsorption duration and efficiency of this method is unstable.: Objective: In this study, a ... ...

Abstract	Background: The adsorption of activated charcoal is currently a major clinical treatment for acute organophosphorus pesticide poisoning (AOPP). However, the adsorption duration and efficiency of this method is unstable. Objective: In this study, a hydrogel embedding activated charcoal was prepared and its alleviating effects on AOPP were investigated. Methods: A composite hydrogel using sodium alginate and polyvinyl alcohol (SA-PVA) hydrogel was prepared in this study. The structural properties of the SA-PVA hydrogel were characterized via multiple analysis including FTIR, TGA, XRD, SEM, tensile strength and expansion rate. Based on these, activated charcoal (AC) was embedded within the SA-PVA hydrogel (SA-PVA-AC) and it was used for the treatment of AOPP. Results: Structural characterization indicated SA-PVA hydrogel possesses excellent mechanical properties and biocompatibility. The in vivo study demonstrated that SA-PVA-AC significantly alleviated the inflammation and oxidative damage in the liver, as evidenced by reduced levels of IL-6, TNF-α, and, IL-1β, SOD, and MDA. Furthermore, SA-PVA-AC treatment effectively re-regulated the activities of serum AST and ALT, exhibiting an improved effect on liver function. Conclusion: The findings suggest that activated charcoal embedded within SA-PVA hydrogel has significant potential as a therapeutic agent in treating AOPP, and offering a novel approach to managing pesticide-induced toxicity.
Language	English
Publishing date	2024-04-11
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1066216-9
ISSN	1878-3619 ; 0959-2989
ISSN (online)	1878-3619
ISSN	0959-2989
DOI	10.3233/BME-240007
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Zs.A 3238: Show issues

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Article ; Online: Esophageal Liposarcoma of the Oropharyngeal-Esophageal Junction.

Dai, Ting / Peng, Ying-Jie / He, Ya-Qiong

The American journal of gastroenterology

2024

Language	English
Publishing date	2024-03-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	390122-1
ISSN	1572-0241 ; 0002-9270
ISSN (online)	1572-0241
ISSN	0002-9270
DOI	10.14309/ajg.0000000000002742
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Article ; Online: Mass Spectrometry Evidence for Forming Schiff Base 3'-DNA-Histone Cross-Links from Abasic Sites

Peng, Ying / Bryan, Cameron / Yang, Kun

Chemical research in toxicology

2024 Volume 37, Issue 2, Page(s) 216–219

Abstract: Histones catalyze DNA strand incision at apurinic/apyrimidinic (AP) sites accompanied by the formation of reversible but long-lived DNA-protein cross-links at 3'-termini (3'-histone-DPCs). However, the chemical structures of 3'-histone-DPCs are not well ... ...

Abstract	Histones catalyze DNA strand incision at apurinic/apyrimidinic (AP) sites accompanied by the formation of reversible but long-lived DNA-protein cross-links at 3'-termini (3'-histone-DPCs). However, the chemical structures of 3'-histone-DPCs are not well characterized, and whether they are formed in cells is uncertain. In this study, we developed a liquid chromatography with tandem mass spectrometry workflow to characterize DPCs produced from the reaction of histones with AP sites and wish to report evidence that histones cross-link to incised AP sites via Schiff bases. We also demonstrated for the first time that 3'-histone-DPCs are produced endogenously in human embryonic kidney 293T cells.
MeSH term(s)	Humans ; Histones/metabolism ; Schiff Bases/chemistry ; DNA/chemistry ; DNA Damage ; Tandem Mass Spectrometry ; DNA Repair
Chemical Substances	Histones ; Schiff Bases ; DNA (9007-49-2)
Language	English
Publishing date	2024-01-17
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	639353-6
ISSN	1520-5010 ; 0893-228X
ISSN (online)	1520-5010
ISSN	0893-228X
DOI	10.1021/acs.chemrestox.3c00377
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Zs.A 2320: Show issues

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Article ; Online: Energy saving and emission reduction effects of urban digital economy: technology dividends or structural dividends?

Gao, Weilong / Peng, Ying

Environ Sci Pollut Res. 2023 Mar., v. 30, no. 13 p.36851-36871

2023

Abstract: As a new economic form, the digital economy provides new opportunities to save energy and reduce emissions, but it may also become a booster for increasing energy consumption and pollutant emissions, making the sustainable development of cities face ... ...

Abstract	As a new economic form, the digital economy provides new opportunities to save energy and reduce emissions, but it may also become a booster for increasing energy consumption and pollutant emissions, making the sustainable development of cities face serious challenges. It is controversial whether the digital economy contributes to energy saving and emission reduction, and it is unclear what role technological progress and structural transformation play in the relationship between the digital economy and energy saving and emission reduction. In this study, the energy saving and emission reduction effects of the digital economy in cities and its mechanisms are empirically examined from the perspective of technological progress and structural transformation using the two-way fixed effect model and the mediating effect model. The results show that the digital economy increases urban energy consumption and reduces pollution emissions. The energy saving and emission reduction effects of the digital economy are more significant in northeastern cities, large cities, and resource-based cities. The mechanism test shows that the digital economy promotes urban energy saving and emission reduction through green technological progress, mainly because the energy saving from green technological efficiency improvements exceeds the energy rebound from green technological innovation. However, the digital economy has not shown energy saving and emission reduction effects by promoting industrial structural transformation. Specifically, the structural transformation of the secondary industry contributes to urban emission reduction, while the structural transformation of the primary and tertiary industries leads to efficiency loss of energy saving and emission reduction. Our findings provide valuable insights into the synergistic governance of “energy saving” and “emissions reduction” in cities in the digital economy.
Keywords	energy ; governance ; industry ; models ; pollutants ; pollution ; sustainable development ; technology
Language	English
Dates of publication	2023-03
Size	p. 36851-36871.
Publishing place	Springer Berlin Heidelberg
Document type	Article ; Online
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-022-24780-1
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Energy saving and emission reduction effects of urban digital economy: technology dividends or structural dividends?

Gao, Weilong / Peng, Ying

Environmental science and pollution research international

2022 Volume 30, Issue 13, Page(s) 36851–36871

Abstract	As a new economic form, the digital economy provides new opportunities to save energy and reduce emissions, but it may also become a booster for increasing energy consumption and pollutant emissions, making the sustainable development of cities face serious challenges. It is controversial whether the digital economy contributes to energy saving and emission reduction, and it is unclear what role technological progress and structural transformation play in the relationship between the digital economy and energy saving and emission reduction. In this study, the energy saving and emission reduction effects of the digital economy in cities and its mechanisms are empirically examined from the perspective of technological progress and structural transformation using the two-way fixed effect model and the mediating effect model. The results show that the digital economy increases urban energy consumption and reduces pollution emissions. The energy saving and emission reduction effects of the digital economy are more significant in northeastern cities, large cities, and resource-based cities. The mechanism test shows that the digital economy promotes urban energy saving and emission reduction through green technological progress, mainly because the energy saving from green technological efficiency improvements exceeds the energy rebound from green technological innovation. However, the digital economy has not shown energy saving and emission reduction effects by promoting industrial structural transformation. Specifically, the structural transformation of the secondary industry contributes to urban emission reduction, while the structural transformation of the primary and tertiary industries leads to efficiency loss of energy saving and emission reduction. Our findings provide valuable insights into the synergistic governance of "energy saving" and "emissions reduction" in cities in the digital economy.
MeSH term(s)	China ; Cities ; Economic Development ; Environmental Pollutants ; Environmental Pollution ; Industry ; Technology
Chemical Substances	Environmental Pollutants
Language	English
Publishing date	2022-12-23
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-022-24780-1
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Article: Removal and reconstruction: Multi-period price effects on nearby housing from urban village redevelopment

Peng, Ying / Tian, Chuanhao

Land use policy. 2022 Feb., v. 113

2022

Abstract: The removal and reconstruction of urban villages can improve the residential environment in the vicinity and promote the willingness of buyers to pay. A detailed investigation of the price effects on nearby housing generated by urban village ... ...

Abstract	The removal and reconstruction of urban villages can improve the residential environment in the vicinity and promote the willingness of buyers to pay. A detailed investigation of the price effects on nearby housing generated by urban village redevelopment helps to capture the added value of public investment. Previous studies often ignore the temporal variation of the price effects. Furthermore, they confuse the price effects from the removal of dilapidated housing and the construction of new buildings. Based on the listing prices in 2017–2018 and transaction data in 2015 of secondhand residential housing in Hangzhou, China, this paper built a multi-period difference-in-differences model to examine the multi-period price effects from urban village redevelopment on nearby housing and to isolate the removal effects of old buildings and the amenity effects of reconstruction. The results show that (1) An anticipatory effect of up to 13% occurs before the urban village redevelopment; removal and reconstruction will bring a total premium of 20% to nearby housing prices; and the total price effects gradually increase in time and slightly fall back after four years. (2) Less than 15% of the added value comes from the removal of dilapidated housing in an urban village, while more than 85% comes from the reconstruction of new buildings. (3) The price effects of large-scale urban village redevelopment are much more obvious.
Keywords	land policy ; models ; prices ; public investment ; temporal variation ; villages ; China
Language	English
Dates of publication	2022-02
Publishing place	Elsevier Ltd
Document type	Article
ZDB-ID	852476-2
ISSN	0264-8377
ISSN	0264-8377
DOI	10.1016/j.landusepol.2021.105877
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Article ; Online: Causality between inflammatory bowel disease and the cerebral cortex: insights from Mendelian randomization and integrated bioinformatics analysis.

He, Shubei / Peng, Ying / Chen, Xiaofang / Ou, Ying

Frontiers in immunology

2023 Volume 14, Page(s) 1175873

Abstract: Background: Inflammatory bowel disease (IBD), which includes ulcerative colitis (UC) and Crohn's disease (CD), is a chronic, progressive, and recurrent intestinal condition that poses a significant global health burden. The high prevalence of ... ...

Abstract	Background: Inflammatory bowel disease (IBD), which includes ulcerative colitis (UC) and Crohn's disease (CD), is a chronic, progressive, and recurrent intestinal condition that poses a significant global health burden. The high prevalence of neuropsychiatric comorbidities in IBD necessitates the development of targeted management strategies. Methods: Leveraging genetic data from genome-wide association studies and Immunochip genotype analyses of nearly 150,000 individuals, we conducted a two-sample Mendelian randomization study to elucidate the driving force of IBD, UC, and CD on cortical reshaping. Genetic variants mediating the causality were collected to disclose the biological pathways linking intestinal inflammation to brain dysfunction. Results: Here, 115, 69, and 98 instrumental variables genetically predicted IBD, UC, and CD. We found that CD significantly decreased the surface area of the temporal pole gyrus (β = -0.946 mm Conclusion: We explore the causality between intestinal inflammation and altered cortical morphology. It is likely that neuroinflammation-induced damage, impaired neurological function, and persistent nociceptive input lead to morphological changes in the cerebral cortex, which may trigger neuropsychiatric disorders.
MeSH term(s)	Humans ; Genome-Wide Association Study ; Mendelian Randomization Analysis ; Inflammatory Bowel Diseases/genetics ; Crohn Disease ; Colitis, Ulcerative ; Cerebral Cortex ; Computational Biology ; Inflammation
Language	English
Publishing date	2023-07-27
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2606827-8
ISSN	1664-3224 ; 1664-3224
ISSN (online)	1664-3224
ISSN	1664-3224
DOI	10.3389/fimmu.2023.1175873
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Article ; Online: Synthesis and Excision Repair of Site-Specific 3'-End DNA-Histone Cross-Links Derived from Abasic Sites.

Peng, Ying / Wei, Xiaoying / Yang, Kun

Bioconjugate chemistry

2023 Volume 34, Issue 6, Page(s) 983–987

Abstract: Histones catalyze the DNA strand incision at apurinic/apyrimidinic (AP) sites accompanied by formation of reversible but long-lived DNA-protein cross-links (DPCs) at 3'-DNA termini within single-strand breaks. These DPCs need to be removed because 3'- ... ...

Abstract	Histones catalyze the DNA strand incision at apurinic/apyrimidinic (AP) sites accompanied by formation of reversible but long-lived DNA-protein cross-links (DPCs) at 3'-DNA termini within single-strand breaks. These DPCs need to be removed because 3'-hydroxyl is required for gap-filling DNA repair synthesis but are challenging to study because of their reversible nature. Here we report a chemical approach to synthesize stable and site-specific 3'-histone-DPCs and their repair by three nucleases, human AP endonuclease 1, tyrosyl-DNA phosphodiesterase 1, and three-prime repair exonuclease 1. Our method employs oxime ligation to install an alkyne to 3'-DNA terminus, genetic incorporation of an azidohomoalanine to histone H4 at a defined position, and click reaction to conjugate DNA to H4 site-specifically. Using these model DPC substrates, we demonstrated that the DPC repair efficiency is highly affected by the local protein environment, and prior DPC proteolysis facilitates the repair.
MeSH term(s)	Humans ; Histones/metabolism ; DNA Repair ; DNA/metabolism ; DNA Damage
Chemical Substances	Histones ; DNA (9007-49-2)
Language	English
Publishing date	2023-05-15
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1024041-x
ISSN	1520-4812 ; 1043-1802
ISSN (online)	1520-4812
ISSN	1043-1802
DOI	10.1021/acs.bioconjchem.3c00156
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Zs.A 3400: Show issues

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Article: Enhancing Hot Air Drying Efficiency through Electrostatic Field-Ultrasonic Coupling Pretreatment.

Yang, Ri-Fu / Peng, Ying-Ying / Wang, Yu-Rong

Foods (Basel, Switzerland)

2023 Volume 12, Issue 8

Abstract: The drying of compact and biologically active materials presents significant challenges. In this study, we propose using electrostatic field-ultrasonic coupling pretreatment to enhance the drying efficiency of ginkgo fruits. We designed and constructed ... ...

Abstract	The drying of compact and biologically active materials presents significant challenges. In this study, we propose using electrostatic field-ultrasonic coupling pretreatment to enhance the drying efficiency of ginkgo fruits. We designed and constructed an experimental device to investigate the effects of ultrasonic power, pretreatment time, hot air drying temperature, and electrostatic field voltage on the moisture content of the fruits. We used the response surface methodology to identify optimal process conditions and further explored the kinetic model for the moisture content of the fruits under the pretreatment. The results showed that the optimal process parameters for electrostatic-ultrasound pretreatment and the drying of ginkgo fruits were: an electrostatic field voltage of 11.252 kV, an ultrasound power of 590.074 W, a pretreatment time of 32.799 min, and a hot air drying temperature of 85 °C. Under the optimized process conditions, the correlation between the moisture content of ginkgo fruits and the two-term drying kinetics model was the highest. After electrostatic-ultrasound coupling pretreatment, the drying rate of ginkgo fruits was significantly improved during hot air drying.
Language	English
Publishing date	2023-04-21
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2704223-6
ISSN	2304-8158
ISSN	2304-8158
DOI	10.3390/foods12081727
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